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The map label for this gene is 186477260

Identifier: 186477260

GI number: 186477260

Start: 2829495

End: 2830073

Strand: Reverse

Name: 186477260

Synonym: Bphy_2512

Alternate gene names: NA

Gene position: 2830073-2829495 (Counterclockwise)

Preceding gene: 186477267

Following gene: 186477255

Centisome position: 81.34

GC content: 63.9

Gene sequence:

>579_bases
ATGGGCAACCGCTTGAGCAAGATTTCGACACGCACGGGCGACGACGGCACCACAGGTCTCGGAGACGGCAGCCGCGTGCG
CAAGGACGACGCGCGGATTGCGGCGATCGGCGATGTCGACGAGTTGAACTCGAACATCGGCGTCTTGCTGTGCGAAACCT
TGCCCAATGACCTGCGCGTCGCGCTGACGGCGATCCAGCACGATCTGTTCGATCTGGGCGGCGAGCTATGCATTCCGGGC
CATTCGATGATCGCCGATGCGCATCTTGCGCAACTCGATTCATGGCTTGCTGAATACAACGCGACGCTGCCGCCGCTCAG
GGAGTTCATCCTGCCTGCGGGCACGCGCGCAGCGTCGCTTGCACATGTGTGCCGGACGGTTTGCCGGCGCGCAGAGCGAT
CGATCGTCGCGTTGGGTGCCGTCGATGCGATCAACGACGCGCCGCGTCGATATGTGAACCGCTTGTCGGATCTGCTGTTC
GTACTGGCCCGCGTGCTGAACCGGGTGGACGGCGGCGACGACGTGCTGTGGCGCCACGATCGCAGCGCGCAGAAAGACGA
TGCGCAAAGCGGGGAATAG

Upstream 100 bases:

>100_bases
AGCGCGAGGCAGGGCTTCCTTATAATGGATCACAGCATGAACGACATGCCGCGCTGATCCGGATGGATGCATCGCGGACC
AACACGAGGACATGGACATC

Downstream 100 bases:

>100_bases
TGCGCGCCGCGCGGCGGCTCAGGCGGCAGCGAGCGTGACGGGCTCACCGATGCGGCTCATCCTTTCGACGAGTGTGTCGA
TGGTGAACCTGATGGTTTTC

Product: ATP--cobalamin adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase [H]

Number of amino acids: Translated: 192; Mature: 191

Protein sequence:

>192_residues
MGNRLSKISTRTGDDGTTGLGDGSRVRKDDARIAAIGDVDELNSNIGVLLCETLPNDLRVALTAIQHDLFDLGGELCIPG
HSMIADAHLAQLDSWLAEYNATLPPLREFILPAGTRAASLAHVCRTVCRRAERSIVALGAVDAINDAPRRYVNRLSDLLF
VLARVLNRVDGGDDVLWRHDRSAQKDDAQSGE

Sequences:

>Translated_192_residues
MGNRLSKISTRTGDDGTTGLGDGSRVRKDDARIAAIGDVDELNSNIGVLLCETLPNDLRVALTAIQHDLFDLGGELCIPG
HSMIADAHLAQLDSWLAEYNATLPPLREFILPAGTRAASLAHVCRTVCRRAERSIVALGAVDAINDAPRRYVNRLSDLLF
VLARVLNRVDGGDDVLWRHDRSAQKDDAQSGE
>Mature_191_residues
GNRLSKISTRTGDDGTTGLGDGSRVRKDDARIAAIGDVDELNSNIGVLLCETLPNDLRVALTAIQHDLFDLGGELCIPGH
SMIADAHLAQLDSWLAEYNATLPPLREFILPAGTRAASLAHVCRTVCRRAERSIVALGAVDAINDAPRRYVNRLSDLLFV
LARVLNRVDGGDDVLWRHDRSAQKDDAQSGE

Specific function: Unknown

COG id: COG2096

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI16418349, Length=196, Percent_Identity=37.7551020408163, Blast_Score=120, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI115534154, Length=167, Percent_Identity=33.5329341317365, Blast_Score=84, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017858
- InterPro:   IPR002779
- InterPro:   IPR016030
- ProDom:   PD007457 [H]

Pfam domain/function: PF01923 Cob_adeno_trans [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 20794; Mature: 20662

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNRLSKISTRTGDDGTTGLGDGSRVRKDDARIAAIGDVDELNSNIGVLLCETLPNDLRV
CCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEECCHHHHCCCCCEEECCCCCHHHHH
ALTAIQHDLFDLGGELCIPGHSMIADAHLAQLDSWLAEYNATLPPLREFILPAGTRAASL
HHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHH
AHVCRTVCRRAERSIVALGAVDAINDAPRRYVNRLSDLLFVLARVLNRVDGGDDVLWRHD
HHHHHHHHHHHHHCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCC
RSAQKDDAQSGE
CCCCCCCCCCCC
>Mature Secondary Structure 
GNRLSKISTRTGDDGTTGLGDGSRVRKDDARIAAIGDVDELNSNIGVLLCETLPNDLRV
CCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEECCHHHHCCCCCEEECCCCCHHHHH
ALTAIQHDLFDLGGELCIPGHSMIADAHLAQLDSWLAEYNATLPPLREFILPAGTRAASL
HHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHH
AHVCRTVCRRAERSIVALGAVDAINDAPRRYVNRLSDLLFVLARVLNRVDGGDDVLWRHD
HHHHHHHHHHHHHCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCC
RSAQKDDAQSGE
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]