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The map label for this gene is tolR [H]

Identifier: 186477202

GI number: 186477202

Start: 2752244

End: 2752690

Strand: Direct

Name: tolR [H]

Synonym: Bphy_2453

Alternate gene names: 186477202

Gene position: 2752244-2752690 (Clockwise)

Preceding gene: 186477201

Following gene: 186477203

Centisome position: 79.11

GC content: 63.31

Gene sequence:

>447_bases
ATGGCCGGTTCAGTTCGTTCCAGCATGCGCGGCAGCCGCTCGCGCCGCGCGATGGCCGACATCAACGTCGTGCCGTACAT
CGACGTCATGCTCGTGCTGCTCGTGATTTTCATGGTGACCGCGCCGCTCGTGGCGCCGTCCATCGTGAACCTGCCGACGG
TCGGCGGCGCAGCGCCGCAGCAGCAGACGCCGCCCGTCGTCGTCAACATCAAGGCCGACGGCAACATGAGCGTCAAGTAC
AAGGACGACGCAGGCGCGACCCAGCAGGAGACGATGACGCAGGCGGATCTGCGCGGCTTCGTCACCGACCGTCAGGCCTC
GCATCCCGATCAGCCTGTCGTGATTGCCGCCGACAAGACGGTTAAATATGAAGTCGTGATGAACGTGATGTCCGACCTCA
AGGCTCGCGGCGTCAAGCGCGTTGGATTGCTCGTCAAATCGCAATGA

Upstream 100 bases:

>100_bases
GTTACGCGCACGACATCGATCGCCTCGCGATCCGCTTCGAAACCTTCATCGAAGAGTTCTCGAACATCCTGCAGCGTCAG
GCCCATTAAGGAGTCCCACG

Downstream 100 bases:

>100_bases
TCCGCCGACAGAACAACGCCTATCCGCTTCAGCCGCCGCGCGAACGCGGCACAGGGCGCGCCATTGCGCTCGCCGTGCTG
ATGCACGTGCTGCTCGGGTT

Product: protein TolR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 148; Mature: 147

Protein sequence:

>148_residues
MAGSVRSSMRGSRSRRAMADINVVPYIDVMLVLLVIFMVTAPLVAPSIVNLPTVGGAAPQQQTPPVVVNIKADGNMSVKY
KDDAGATQQETMTQADLRGFVTDRQASHPDQPVVIAADKTVKYEVVMNVMSDLKARGVKRVGLLVKSQ

Sequences:

>Translated_148_residues
MAGSVRSSMRGSRSRRAMADINVVPYIDVMLVLLVIFMVTAPLVAPSIVNLPTVGGAAPQQQTPPVVVNIKADGNMSVKY
KDDAGATQQETMTQADLRGFVTDRQASHPDQPVVIAADKTVKYEVVMNVMSDLKARGVKRVGLLVKSQ
>Mature_147_residues
AGSVRSSMRGSRSRRAMADINVVPYIDVMLVLLVIFMVTAPLVAPSIVNLPTVGGAAPQQQTPPVVVNIKADGNMSVKYK
DDAGATQQETMTQADLRGFVTDRQASHPDQPVVIAADKTVKYEVVMNVMSDLKARGVKRVGLLVKSQ

Specific function: Involved in the tonB-independent uptake of proteins [H]

COG id: COG0848

COG function: function code U; Biopolymer transport protein

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbD/tolR family [H]

Homologues:

Organism=Escherichia coli, GI1789380, Length=128, Percent_Identity=39.84375, Blast_Score=78, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014168
- InterPro:   IPR003400 [H]

Pfam domain/function: PF02472 ExbD [H]

EC number: NA

Molecular weight: Translated: 15894; Mature: 15763

Theoretical pI: Translated: 10.34; Mature: 10.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
6.1 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGSVRSSMRGSRSRRAMADINVVPYIDVMLVLLVIFMVTAPLVAPSIVNLPTVGGAAPQ
CCCCHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCC
QQTPPVVVNIKADGNMSVKYKDDAGATQQETMTQADLRGFVTDRQASHPDQPVVIAADKT
CCCCCEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCC
VKYEVVMNVMSDLKARGVKRVGLLVKSQ
CHHHHHHHHHHHHHHCCHHHHHEEEECC
>Mature Secondary Structure 
AGSVRSSMRGSRSRRAMADINVVPYIDVMLVLLVIFMVTAPLVAPSIVNLPTVGGAAPQ
CCCHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCC
QQTPPVVVNIKADGNMSVKYKDDAGATQQETMTQADLRGFVTDRQASHPDQPVVIAADKT
CCCCCEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCC
VKYEVVMNVMSDLKARGVKRVGLLVKSQ
CHHHHHHHHHHHHHHCCHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8955385; 10984043 [H]