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The map label for this gene is ychM [C]

Identifier: 186477148

GI number: 186477148

Start: 2692823

End: 2694541

Strand: Reverse

Name: ychM [C]

Synonym: Bphy_2397

Alternate gene names: 186477148

Gene position: 2694541-2692823 (Counterclockwise)

Preceding gene: 186477150

Following gene: 186477147

Centisome position: 77.45

GC content: 62.77

Gene sequence:

>1719_bases
ATGCGCGACCAGCCGTTGCCGCACCGCAGCTTCTCCCTCCCCATTCTCGACTGGGTTCGCCACTATGAGAAGTCGTGGGT
CAAGCCCGACATCATTGCGGGCGTCACGGCTGCCGCTGTCGTGTTGCCGAAGGCGATGGCTTACGCCACTGTTGCAGGGC
TTCCCGTGCAGGTGGGTCTCTACACAGCCTTCGTGCCCATGGTGGTCTATGCGCTGCTCGGCACGTCAAGGCCACTCAGC
GTCAGCACGAGTGCAACTCTAGCCATTCTAACGGCAGCCGCACTCGGGCAGGTCGCTCCGGGAGGCGGCGCGGCTCAACT
GGCCATTGCAACTGCGACCCTCACGGTACTGGTCGGTGGCATCCTCATTCTGGCCGCGCTGCTCAGATTTGGTTTCGTCG
CAAATTTCATTTCAGAGCCGGTGCTAACGGGCTTCAAGGGAGGCATTGCAATCGTCATTGTCCTAGACCAGTTGCCCAAG
CTGATCGGTCTCCATGTTGTGAAGGGTTCCTTCTTTCATAACGTGTATGCGTTAGTCACCGGGCTTCCACACCTTTCGAC
GGCGACCGTCGCTGTCGGACTTGTGACGATTGCGGTGCTGGTCGCGCTTGAACACTTCTATCCAAAGTCACCGGCCCCGC
TCATCGCGGTGGCGCTGGGGATTGCCGGTGTCGGCCTCTTAGGGCTGGGAAAGTATGGAGTCTCGGTCGTCGGCCACATT
CCGACGGGGCTGCCGTCGCTCGTGATGCCGGACCTCGCGCTCGTCGAGGCGCTCTGGCCGGCGGCGGCAGGTATCGCGCT
GATGAGCTTCACCGAAACGATCGCCTCGGGGCGCGCGTTCGCCCAGAGCGGTGAACCCGTTCCGCAGCCGAACCGTGAAC
TGCTGGCGACGGGGCTCGGCAACGCAGCAGGCGCGCTGCTGGGCGCCATGCCCGCAGGCGGCGGCACGACCCAGACGGCG
GTCAACCGGCTGGTGGGCGCGCATTCGCAGCTGGCGGAATTGGTGACGGCCGCCGTCACCCTCGCCACGATGGTCCTGCT
CGCGCCGCTGATCGGCCTCATGCCGCATGCGACGCTCGCCGGGGTCGTGATCGTCTATTCTGTAGGCCTTTTCAAGCCAG
CGGACTTCCGGGCGATTCTCTCCGTCAGGCGCACTGAGTTCGTCTGGGCCGTCGTGGCGCTCGCCGGCGTCGTGCTGCTC
GGTACGTTACAAGGCATTCTGATTGCCATCCTCGTTTCGCTGGTGGCGCTAGCGCACCAAGTGTCCGATCCTCCGATTTA
CGTCCTGCGTCGCAAGCGCGGCACGAACGTGTTCCGTCCCGTATCCGCCCAGCACCCCGACGATGAGGAATTCCCCGGGC
TCCTGCTTTTACGGCCCGAGGGGCGGATCTTTTTCGTTAATGCTTCCAACCTTGGTCATAAGATCGCGCCGCTGGTCGAA
AGGGCTCGGCCTCAAGTGGTCGCGCTGGATATGCGGGCGGTATTCGATCTCGAATATACCGCGCTGAAGATGTGGACCGA
GGCTGAAAAGAAATTCCGCGAGCACGGGATTGCCGTATGGCTCGTTGGCTTGAACCCAGATGTGTTCGCCGTCGTGGAGA
AGGCGCCACTCGGAAAGGCGCTTGGACACGAGCGGATGTTTCTCAATCTCGAGCAGGCGCTTGCTGCATGGCATGCCTTG
CAAGACAAGCAGAACGCGTCGCCGGGCCTCGTGCGGTGA

Upstream 100 bases:

>100_bases
GTGCTAAGGTTGGCGGACTTTGCGCTCTGCACGCGGCATCAGGGACCCGACGCCAGCGTCGCACTCCCTGGTGCGTTTTG
GCTTTTCCCGGAGACCAGTC

Downstream 100 bases:

>100_bases
GCAGGGTGGCGCCGCGCGATGAGCCAGCGGTGGATTTGACGGCACCCGCTACTTGACGGGCAGGTGCCAGTTGTCGCGAG
CGGTTCAACTCGGGGTAAGG

Product: sulfate transporter

Products: Proton [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 572; Mature: 572

Protein sequence:

>572_residues
MRDQPLPHRSFSLPILDWVRHYEKSWVKPDIIAGVTAAAVVLPKAMAYATVAGLPVQVGLYTAFVPMVVYALLGTSRPLS
VSTSATLAILTAAALGQVAPGGGAAQLAIATATLTVLVGGILILAALLRFGFVANFISEPVLTGFKGGIAIVIVLDQLPK
LIGLHVVKGSFFHNVYALVTGLPHLSTATVAVGLVTIAVLVALEHFYPKSPAPLIAVALGIAGVGLLGLGKYGVSVVGHI
PTGLPSLVMPDLALVEALWPAAAGIALMSFTETIASGRAFAQSGEPVPQPNRELLATGLGNAAGALLGAMPAGGGTTQTA
VNRLVGAHSQLAELVTAAVTLATMVLLAPLIGLMPHATLAGVVIVYSVGLFKPADFRAILSVRRTEFVWAVVALAGVVLL
GTLQGILIAILVSLVALAHQVSDPPIYVLRRKRGTNVFRPVSAQHPDDEEFPGLLLLRPEGRIFFVNASNLGHKIAPLVE
RARPQVVALDMRAVFDLEYTALKMWTEAEKKFREHGIAVWLVGLNPDVFAVVEKAPLGKALGHERMFLNLEQALAAWHAL
QDKQNASPGLVR

Sequences:

>Translated_572_residues
MRDQPLPHRSFSLPILDWVRHYEKSWVKPDIIAGVTAAAVVLPKAMAYATVAGLPVQVGLYTAFVPMVVYALLGTSRPLS
VSTSATLAILTAAALGQVAPGGGAAQLAIATATLTVLVGGILILAALLRFGFVANFISEPVLTGFKGGIAIVIVLDQLPK
LIGLHVVKGSFFHNVYALVTGLPHLSTATVAVGLVTIAVLVALEHFYPKSPAPLIAVALGIAGVGLLGLGKYGVSVVGHI
PTGLPSLVMPDLALVEALWPAAAGIALMSFTETIASGRAFAQSGEPVPQPNRELLATGLGNAAGALLGAMPAGGGTTQTA
VNRLVGAHSQLAELVTAAVTLATMVLLAPLIGLMPHATLAGVVIVYSVGLFKPADFRAILSVRRTEFVWAVVALAGVVLL
GTLQGILIAILVSLVALAHQVSDPPIYVLRRKRGTNVFRPVSAQHPDDEEFPGLLLLRPEGRIFFVNASNLGHKIAPLVE
RARPQVVALDMRAVFDLEYTALKMWTEAEKKFREHGIAVWLVGLNPDVFAVVEKAPLGKALGHERMFLNLEQALAAWHAL
QDKQNASPGLVR
>Mature_572_residues
MRDQPLPHRSFSLPILDWVRHYEKSWVKPDIIAGVTAAAVVLPKAMAYATVAGLPVQVGLYTAFVPMVVYALLGTSRPLS
VSTSATLAILTAAALGQVAPGGGAAQLAIATATLTVLVGGILILAALLRFGFVANFISEPVLTGFKGGIAIVIVLDQLPK
LIGLHVVKGSFFHNVYALVTGLPHLSTATVAVGLVTIAVLVALEHFYPKSPAPLIAVALGIAGVGLLGLGKYGVSVVGHI
PTGLPSLVMPDLALVEALWPAAAGIALMSFTETIASGRAFAQSGEPVPQPNRELLATGLGNAAGALLGAMPAGGGTTQTA
VNRLVGAHSQLAELVTAAVTLATMVLLAPLIGLMPHATLAGVVIVYSVGLFKPADFRAILSVRRTEFVWAVVALAGVVLL
GTLQGILIAILVSLVALAHQVSDPPIYVLRRKRGTNVFRPVSAQHPDDEEFPGLLLLRPEGRIFFVNASNLGHKIAPLVE
RARPQVVALDMRAVFDLEYTALKMWTEAEKKFREHGIAVWLVGLNPDVFAVVEKAPLGKALGHERMFLNLEQALAAWHAL
QDKQNASPGLVR

Specific function: Expression in E.coli induces sulfate uptake during early-to mid-log phase growth. Uptake is maximal at pH 6.0, is sulfate-specific, requires E.coli CysA and the transmembrane segment but not the STAS domain of the protein [H]

COG id: COG0659

COG function: function code P; Sulfate permease and related transporters (MFS superfamily)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

Organism=Homo sapiens, GI94721259, Length=484, Percent_Identity=29.5454545454545, Blast_Score=178, Evalue=1e-44,
Organism=Homo sapiens, GI94721257, Length=484, Percent_Identity=29.5454545454545, Blast_Score=178, Evalue=2e-44,
Organism=Homo sapiens, GI94721253, Length=484, Percent_Identity=29.5454545454545, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI94721255, Length=484, Percent_Identity=29.5454545454545, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI262206105, Length=590, Percent_Identity=28.9830508474576, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI262206075, Length=590, Percent_Identity=28.9830508474576, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI262206069, Length=590, Percent_Identity=28.9830508474576, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI262206063, Length=590, Percent_Identity=28.9830508474576, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI39752683, Length=487, Percent_Identity=26.694045174538, Blast_Score=169, Evalue=5e-42,
Organism=Homo sapiens, GI45827800, Length=487, Percent_Identity=26.694045174538, Blast_Score=169, Evalue=6e-42,
Organism=Homo sapiens, GI45827802, Length=451, Percent_Identity=27.7161862527716, Blast_Score=155, Evalue=1e-37,
Organism=Homo sapiens, GI269784651, Length=486, Percent_Identity=26.3374485596708, Blast_Score=149, Evalue=9e-36,
Organism=Homo sapiens, GI100913030, Length=629, Percent_Identity=23.8473767885533, Blast_Score=139, Evalue=9e-33,
Organism=Homo sapiens, GI4505697, Length=397, Percent_Identity=27.7078085642317, Blast_Score=136, Evalue=6e-32,
Organism=Homo sapiens, GI47131207, Length=508, Percent_Identity=27.9527559055118, Blast_Score=133, Evalue=4e-31,
Organism=Homo sapiens, GI20336272, Length=508, Percent_Identity=27.9527559055118, Blast_Score=133, Evalue=4e-31,
Organism=Homo sapiens, GI16418413, Length=386, Percent_Identity=26.6839378238342, Blast_Score=126, Evalue=5e-29,
Organism=Homo sapiens, GI217272867, Length=386, Percent_Identity=26.6839378238342, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI4557535, Length=501, Percent_Identity=22.5548902195609, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI16306483, Length=519, Percent_Identity=24.0847784200385, Blast_Score=118, Evalue=2e-26,
Organism=Homo sapiens, GI20336282, Length=519, Percent_Identity=24.0847784200385, Blast_Score=118, Evalue=2e-26,
Organism=Homo sapiens, GI16418457, Length=623, Percent_Identity=20.2247191011236, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI301601599, Length=623, Percent_Identity=20.2247191011236, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI65506789, Length=380, Percent_Identity=27.8947368421053, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI45827804, Length=261, Percent_Identity=29.5019157088123, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI301601602, Length=595, Percent_Identity=19.327731092437, Blast_Score=74, Evalue=5e-13,
Organism=Escherichia coli, GI87081859, Length=346, Percent_Identity=31.5028901734104, Blast_Score=100, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI86564196, Length=503, Percent_Identity=25.4473161033797, Blast_Score=158, Evalue=7e-39,
Organism=Caenorhabditis elegans, GI17566848, Length=564, Percent_Identity=25.177304964539, Blast_Score=154, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17562578, Length=497, Percent_Identity=24.3460764587525, Blast_Score=145, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI17551690, Length=525, Percent_Identity=23.4285714285714, Blast_Score=142, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI86565215, Length=579, Percent_Identity=22.279792746114, Blast_Score=128, Evalue=8e-30,
Organism=Caenorhabditis elegans, GI193203292, Length=554, Percent_Identity=23.826714801444, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI86564876, Length=433, Percent_Identity=21.7090069284065, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI86565213, Length=271, Percent_Identity=25.830258302583, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI86565209, Length=230, Percent_Identity=24.7826086956522, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI86565211, Length=230, Percent_Identity=24.7826086956522, Blast_Score=69, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6325260, Length=569, Percent_Identity=23.3743409490334, Blast_Score=139, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6323121, Length=465, Percent_Identity=26.6666666666667, Blast_Score=135, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6319771, Length=395, Percent_Identity=24.5569620253165, Blast_Score=124, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24649801, Length=587, Percent_Identity=25.5536626916525, Blast_Score=155, Evalue=5e-38,
Organism=Drosophila melanogaster, GI24651449, Length=599, Percent_Identity=22.5375626043406, Blast_Score=152, Evalue=6e-37,
Organism=Drosophila melanogaster, GI21358229, Length=579, Percent_Identity=24.8704663212435, Blast_Score=150, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24666186, Length=422, Percent_Identity=28.6729857819905, Blast_Score=148, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24647160, Length=554, Percent_Identity=23.6462093862816, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI21355087, Length=549, Percent_Identity=23.3151183970856, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI85815873, Length=452, Percent_Identity=26.3274336283186, Blast_Score=129, Evalue=6e-30,
Organism=Drosophila melanogaster, GI21358633, Length=527, Percent_Identity=22.7703984819734, Blast_Score=127, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24663084, Length=571, Percent_Identity=25.9194395796848, Blast_Score=126, Evalue=4e-29,
Organism=Drosophila melanogaster, GI21357695, Length=571, Percent_Identity=25.9194395796848, Blast_Score=126, Evalue=4e-29,
Organism=Drosophila melanogaster, GI19922482, Length=450, Percent_Identity=24.6666666666667, Blast_Score=120, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645
- InterPro:   IPR001902
- InterPro:   IPR011547 [H]

Pfam domain/function: PF01740 STAS; PF00916 Sulfate_transp [H]

EC number: NA

Molecular weight: Translated: 59946; Mature: 59946

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: PS50801 STAS ; PS01130 SLC26A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HCCHHHHEEHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure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HCCHHHHEEHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; SO42- [Periplasm] [C]

Specific reaction: Proton [Periplasm] + SO42- [Periplasm] = Proton [Cytoplasm] + SO42- [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]