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The map label for this gene is yecS [H]

Identifier: 186477119

GI number: 186477119

Start: 2660468

End: 2661124

Strand: Reverse

Name: yecS [H]

Synonym: Bphy_2368

Alternate gene names: 186477119

Gene position: 2661124-2660468 (Counterclockwise)

Preceding gene: 186477120

Following gene: 186477118

Centisome position: 76.49

GC content: 60.43

Gene sequence:

>657_bases
ATGTTTTTGCAGAACGCAATCGACTTTCTGCCGATCCTGCTGAAGGGCGCTGTCATCACCATCGAGATCACAGCCTGTGC
ATTTGTGCTCAGCTCCATTCTCGGTCTCGTGCTGGCGCTGTTGAAGGTGTCGCGCAACCGCGCGGCATCGACGTTCGGCA
GCACCGTGATCAATCTGATTCGCGGGCTGCCGATCATCGTCCAGCTGTTTTATATCTACTTCGTGCTGCCCGACCTGGGC
GTGCAACTGTCGGCGTTCCAGGCTGGCGTGATCGGTCTCGGTATCGCGTACTCGGCGTATCAGGCTGAGAACTTCCGCGC
GGGCATCGAGGCGATCGATCACGGGCAGATCGAAGCCGCGCACGCGATCGGCATGCGCGGCCCGCTGATCATGCGGCGCG
TGGTGTTGCCGCAGGCCTTCAGGATCGCGCTGCCGCCTTACGGCAATACGCTGGTGATGCTGCTGAAAGATTCCTCGGTG
GCATCGACGATCACCGTCGCTGAAATTACGCGCGCCGGGCAACTGATTGCATCGTCGACGTTCCAGAACATGACGGTCTA
CACGCTCGTCGCGCTGCTCTACCTGGTGCTGAGCCTGCCGCTGATGTTCGGCGTCAACCAGATCGGCAAGCGGCTCGCCT
TGAGGAAAAGCCGATGA

Upstream 100 bases:

>100_bases
GAAGTGGCACATGGGCTGACAGGGCAGCCGTATCGCTGCATTCGAAACTGTCCGCGTGTGAACGCGCGCGGACGATTTGC
CATGCGTGTCGGGAGCCGCG

Downstream 100 bases:

>100_bases
TCGAGATCAACGCAATACACAAGCGCTTTCACAATCAGGAAGTGCTCAAGGGCGTGAGCCTGAGCGTAAAGGCGGGTGAA
GTCGTATGCCTGATCGGACC

Product: polar amino acid ABC transporter inner membrane subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MFLQNAIDFLPILLKGAVITIEITACAFVLSSILGLVLALLKVSRNRAASTFGSTVINLIRGLPIIVQLFYIYFVLPDLG
VQLSAFQAGVIGLGIAYSAYQAENFRAGIEAIDHGQIEAAHAIGMRGPLIMRRVVLPQAFRIALPPYGNTLVMLLKDSSV
ASTITVAEITRAGQLIASSTFQNMTVYTLVALLYLVLSLPLMFGVNQIGKRLALRKSR

Sequences:

>Translated_218_residues
MFLQNAIDFLPILLKGAVITIEITACAFVLSSILGLVLALLKVSRNRAASTFGSTVINLIRGLPIIVQLFYIYFVLPDLG
VQLSAFQAGVIGLGIAYSAYQAENFRAGIEAIDHGQIEAAHAIGMRGPLIMRRVVLPQAFRIALPPYGNTLVMLLKDSSV
ASTITVAEITRAGQLIASSTFQNMTVYTLVALLYLVLSLPLMFGVNQIGKRLALRKSR
>Mature_218_residues
MFLQNAIDFLPILLKGAVITIEITACAFVLSSILGLVLALLKVSRNRAASTFGSTVINLIRGLPIIVQLFYIYFVLPDLG
VQLSAFQAGVIGLGIAYSAYQAENFRAGIEAIDHGQIEAAHAIGMRGPLIMRRVVLPQAFRIALPPYGNTLVMLLKDSSV
ASTITVAEITRAGQLIASSTFQNMTVYTLVALLYLVLSLPLMFGVNQIGKRLALRKSR

Specific function: Probably part of the binding-protein-dependent transport system yecCS for an amino acid; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788226, Length=196, Percent_Identity=42.3469387755102, Blast_Score=159, Evalue=1e-40,
Organism=Escherichia coli, GI1787030, Length=209, Percent_Identity=33.9712918660287, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1787087, Length=235, Percent_Identity=31.4893617021277, Blast_Score=110, Evalue=6e-26,
Organism=Escherichia coli, GI1788646, Length=201, Percent_Identity=32.3383084577114, Blast_Score=104, Evalue=3e-24,
Organism=Escherichia coli, GI1786874, Length=213, Percent_Identity=30.9859154929577, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1786873, Length=219, Percent_Identity=29.6803652968037, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788645, Length=206, Percent_Identity=31.5533980582524, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1787086, Length=220, Percent_Identity=28.6363636363636, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI48994930, Length=169, Percent_Identity=30.1775147928994, Blast_Score=75, Evalue=2e-15,
Organism=Escherichia coli, GI87082239, Length=185, Percent_Identity=27.027027027027, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 23565; Mature: 23565

Theoretical pI: Translated: 10.38; Mature: 10.38

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLQNAIDFLPILLKGAVITIEITACAFVLSSILGLVLALLKVSRNRAASTFGSTVINLI
CCHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGLPIIVQLFYIYFVLPDLGVQLSAFQAGVIGLGIAYSAYQAENFRAGIEAIDHGQIEAA
CCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
HAIGMRGPLIMRRVVLPQAFRIALPPYGNTLVMLLKDSSVASTITVAEITRAGQLIASST
HHHCCCCHHHHHHHHHCHHHEEECCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHH
FQNMTVYTLVALLYLVLSLPLMFGVNQIGKRLALRKSR
HHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCC
>Mature Secondary Structure
MFLQNAIDFLPILLKGAVITIEITACAFVLSSILGLVLALLKVSRNRAASTFGSTVINLI
CCHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGLPIIVQLFYIYFVLPDLGVQLSAFQAGVIGLGIAYSAYQAENFRAGIEAIDHGQIEAA
CCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
HAIGMRGPLIMRRVVLPQAFRIALPPYGNTLVMLLKDSSVASTITVAEITRAGQLIASST
HHHCCCCHHHHHHHHHCHHHEEECCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHH
FQNMTVYTLVALLYLVLSLPLMFGVNQIGKRLALRKSR
HHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]