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The map label for this gene is adrA [H]

Identifier: 186477107

GI number: 186477107

Start: 2643894

End: 2644853

Strand: Reverse

Name: adrA [H]

Synonym: Bphy_2356

Alternate gene names: 186477107

Gene position: 2644853-2643894 (Counterclockwise)

Preceding gene: 186477108

Following gene: 186477104

Centisome position: 76.02

GC content: 62.81

Gene sequence:

>960_bases
ATGTTGCGACCGCCTATCCCCGACAACGAAAGCGAGCGCGTGGAGACGCTGCGTTCGCTGCATATCCTCGATACACCGCC
AGAAGAACGGTTCGACCGTCTGACGCGCCTCGCGCGACGCCTGTTCGGCGTGCCCATTGCCGCCGTGACGCTGGTCGACA
GCCATCGACAATGGTTCAAGTCGCATCCCGGCCTCGAAGCCTCCGAAACGCCGCGCGACGTGTCCTTCTGTGGTCATGCC
ATTGCCGACGACGACCTGTTTCTCGTGAACGACGCATCGCTCGACGTGCGCTTCGCCGACAATCCGCTGGTAACGGGCGA
CCCGAACATCCGCTTCTATGCGGGCTATCCGCTTACCGTCAGCAACGGCAGCCGGCTCGGCACACTGTGTCTGATCGATG
TGAAGCCACGTGCGCTCGATGACGAAGAGCGGGTGCTGTTGCGCGATCTTGCACGCATGGCCGAGCAGGAAATCGCCGCG
GTGCAGCTCGCAACCACCGACGAGCTGACGGGCCTGTCGAATCGCCGTGGCTTCGAAGCGCTCGCGCAGCACGCGATCAA
ACACTGCAAGCGTGCGCAGAAGCCTGCGTCGCTGCTGTTCTTCGATCTGAACGGTTTCAAGCAGATCAACGACGTGTTTG
GTCACGCGGAAGGGGACCGCGCGTTGATTGCATTTGCAGCGGTATTGCGCACGGCGCTGCGCGACAGCGATGTGATCGGC
CGGCTAGGCGGCGACGAGTTCGTCGTGCTGCTGACCGATTCGGATCAGCAAGGCACGCTGCAGACCATCGAGCGGCTCAG
GCATCAGCTGGACCTGCAGAACCAGTCGGCGCAGGCGCCTTATCAGCTGCATTGCAGCGTGGGCACGGCGACATACACGC
CCGACAGTCCGCGGAGCATCGATGATCTGCTCGCGCAAGCCGACGTCGCGATGTACGCGAACAAGCGCGCACAACGCTAA

Upstream 100 bases:

>100_bases
GTCGCTCGCGGATAAAATTCATGTTTGGTTCCGTTCAACCTGCGGCGACACGCGGGGTGCTAAACCAGCATCGCGCGTTC
GTGTTTTAACCGGACCTCGA

Downstream 100 bases:

>100_bases
AGGCCGCACTGCTGCGCACCTGTTCGCGCAGCCGATGGGCCGCCTGTGCGTGGTGCACGCTCAGCGGTTTTCCAGCACCC
ACCTTTCTTCACGTTCGAGC

Product: GAF sensor-containing diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MLRPPIPDNESERVETLRSLHILDTPPEERFDRLTRLARRLFGVPIAAVTLVDSHRQWFKSHPGLEASETPRDVSFCGHA
IADDDLFLVNDASLDVRFADNPLVTGDPNIRFYAGYPLTVSNGSRLGTLCLIDVKPRALDDEERVLLRDLARMAEQEIAA
VQLATTDELTGLSNRRGFEALAQHAIKHCKRAQKPASLLFFDLNGFKQINDVFGHAEGDRALIAFAAVLRTALRDSDVIG
RLGGDEFVVLLTDSDQQGTLQTIERLRHQLDLQNQSAQAPYQLHCSVGTATYTPDSPRSIDDLLAQADVAMYANKRAQR

Sequences:

>Translated_319_residues
MLRPPIPDNESERVETLRSLHILDTPPEERFDRLTRLARRLFGVPIAAVTLVDSHRQWFKSHPGLEASETPRDVSFCGHA
IADDDLFLVNDASLDVRFADNPLVTGDPNIRFYAGYPLTVSNGSRLGTLCLIDVKPRALDDEERVLLRDLARMAEQEIAA
VQLATTDELTGLSNRRGFEALAQHAIKHCKRAQKPASLLFFDLNGFKQINDVFGHAEGDRALIAFAAVLRTALRDSDVIG
RLGGDEFVVLLTDSDQQGTLQTIERLRHQLDLQNQSAQAPYQLHCSVGTATYTPDSPRSIDDLLAQADVAMYANKRAQR
>Mature_319_residues
MLRPPIPDNESERVETLRSLHILDTPPEERFDRLTRLARRLFGVPIAAVTLVDSHRQWFKSHPGLEASETPRDVSFCGHA
IADDDLFLVNDASLDVRFADNPLVTGDPNIRFYAGYPLTVSNGSRLGTLCLIDVKPRALDDEERVLLRDLARMAEQEIAA
VQLATTDELTGLSNRRGFEALAQHAIKHCKRAQKPASLLFFDLNGFKQINDVFGHAEGDRALIAFAAVLRTALRDSDVIG
RLGGDEFVVLLTDSDQQGTLQTIERLRHQLDLQNQSAQAPYQLHCSVGTATYTPDSPRSIDDLLAQADVAMYANKRAQR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1786584, Length=168, Percent_Identity=34.5238095238095, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI145693134, Length=157, Percent_Identity=36.3057324840764, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI87081977, Length=263, Percent_Identity=29.6577946768061, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1788381, Length=209, Percent_Identity=32.0574162679426, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1787541, Length=157, Percent_Identity=33.1210191082803, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI87082007, Length=177, Percent_Identity=31.638418079096, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI87081881, Length=181, Percent_Identity=33.1491712707182, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI87081974, Length=153, Percent_Identity=32.6797385620915, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787262, Length=161, Percent_Identity=28.5714285714286, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788085, Length=153, Percent_Identity=29.4117647058824, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1788956, Length=193, Percent_Identity=34.1968911917098, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787802, Length=158, Percent_Identity=29.1139240506329, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1787816, Length=159, Percent_Identity=27.0440251572327, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR007894 [H]

Pfam domain/function: PF00990 GGDEF; PF05230 MASE2 [H]

EC number: NA

Molecular weight: Translated: 35492; Mature: 35492

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRPPIPDNESERVETLRSLHILDTPPEERFDRLTRLARRLFGVPIAAVTLVDSHRQWFK
CCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
SHPGLEASETPRDVSFCGHAIADDDLFLVNDASLDVRFADNPLVTGDPNIRFYAGYPLTV
HCCCCCCCCCCCHHHHHCCCCCCCCEEEEECCCEEEEECCCCEEECCCCEEEEECCEEEE
SNGSRLGTLCLIDVKPRALDDEERVLLRDLARMAEQEIAAVQLATTDELTGLSNRRGFEA
CCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHEEEEECCHHHCCCCCCCCHHH
LAQHAIKHCKRAQKPASLLFFDLNGFKQINDVFGHAEGDRALIAFAAVLRTALRDSDVIG
HHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHC
RLGGDEFVVLLTDSDQQGTLQTIERLRHQLDLQNQSAQAPYQLHCSVGTATYTPDSPRSI
CCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCEECCCCCCCCH
DDLLAQADVAMYANKRAQR
HHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLRPPIPDNESERVETLRSLHILDTPPEERFDRLTRLARRLFGVPIAAVTLVDSHRQWFK
CCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
SHPGLEASETPRDVSFCGHAIADDDLFLVNDASLDVRFADNPLVTGDPNIRFYAGYPLTV
HCCCCCCCCCCCHHHHHCCCCCCCCEEEEECCCEEEEECCCCEEECCCCEEEEECCEEEE
SNGSRLGTLCLIDVKPRALDDEERVLLRDLARMAEQEIAAVQLATTDELTGLSNRRGFEA
CCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHEEEEECCHHHCCCCCCCCHHH
LAQHAIKHCKRAQKPASLLFFDLNGFKQINDVFGHAEGDRALIAFAAVLRTALRDSDVIG
HHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHC
RLGGDEFVVLLTDSDQQGTLQTIERLRHQLDLQNQSAQAPYQLHCSVGTATYTPDSPRSI
CCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCEECCCCCCCCH
DDLLAQADVAMYANKRAQR
HHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]