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The map label for this gene is atoS [C]

Identifier: 186477108

GI number: 186477108

Start: 2645022

End: 2646623

Strand: Reverse

Name: atoS [C]

Synonym: Bphy_2357

Alternate gene names: 186477108

Gene position: 2646623-2645022 (Counterclockwise)

Preceding gene: 186477110

Following gene: 186477107

Centisome position: 76.07

GC content: 62.23

Gene sequence:

>1602_bases
ATGGATACCAACCTTACTGTCACGACCATCCGGAGCGGCGCGCACCGTATTACCGATCATCAGGACGACATCTTCTTCGC
CGCCGTATCGACGACCCGCATGCCGATGGTCGTCACCGATCCGCATCTGCCCGACCACCCCGTGATCTTCGCGAACCATG
CGTTCTTGCGCATGACGGGTTACGAGCTGACGGAGATCATCGGCAGCAATTGCCGCTTTCTGCAAGGACCGGAGACGGAC
CGCGCGACCATCGACGAAGTGCGGGCCGCAGTCGCGGATCGCCGCGAGCTCGCCACAGAGATACTCAATTATCGCAAGGA
CGGCTCGACGTTCTGGAACGCGCTGTTTATTTCGCCTGTGTTCAACGAACAGGGCGAACTGGTCTATTTCTTCGGCTCGC
AACTGGATGTCAGCCGCCGCCGCGACGCCGAAGACGCGCTGCATCAGGCGCAGAAGATGGAGGCGCTCGGCCAGTTGACG
GGCGGCATCGCGCACGACTTCAACAACCTGCTGCAGGTGATGGCAGGCTACGTGGATGTGCTGCAAATGGGCATCGAAGG
CCATGCGCAAAGCGCGGTGATGGCGCAAAGCCTGGATCGCATCCGCGGCGCGGTCGCGAAGGCGACCACGCTGACGCAAC
AGTTGCTTGCGTTCGCGCGCAAGCAGAAGCTCGTGGGGCGCACGGTCAATCTGAACACGCTGGCGGACGGCATGGTCGAG
CTCGCGCGGCGCACGCTTGGCGGCAACATATCGCTGAAGACGGAATACGAAGAAGGACTCGGCAATTGCCGCGTCGACTC
GACCCAGCTCGAAGTCGCGTTGCTGAACGTGCTGCTCAATGCGCGCGACGCGCTCGCCTCGCGGCGCGACGGCGTGGTGA
CGGTGCGCACGGAGACCGTTGAGTTGGAACAGCAGGAGACAGTCGGCTTCGCCGACTTGCGCTCGGGTTGCTATGTGACC
ATCGCCATTTCCGACAACGGCTGCGGCATCCCGCCCGAAATACTCGACCGCGTGATGGACCCGTTCTTCACGACCAAGGG
CGAGGGCAAGGGTACGGGTCTGGGGCTGTCGATGGTATATGGCTTTGCCAAACAGTCGGGCGGCGCGGTCAACCTGTATT
CGGAGCCCGGTGTCGGCACAACGCTGCGGCTTTACTTCCCCGCTGTGGGCGGCATTGCGCAACGCCGTCCGTCCGCGCCG
AAAGCGATTGAAAAGGCGGGCAACGAAATGATCCTGATCGTCGACGATCGCGTGGAAGTGGCCGAGGTCGCACAAGCGAT
GCTCGAGCAGATCGGCTATCGCACGCGAGTCGTGCTGAATACGAAAGAGGCGATGGACATCCTGCAGGAGGGCGCGCACC
TCGACCTGCTGTTCACCGACCTCATCATGCCCGGCAACATGAACGGTGTGATGCTCGCGCGCGAGGCGCGGCGTCTGCAT
CCGAAGATCAAGGTGCTGCTGACCACGGGTTACGCCGACGCGTCGATGGAACGGACCGATGCAAACGGCAGCGAGTTCGA
CATCATTCACAAGCCATACAGGCGAGCGGAACTGGCGCGCAAGGTGAGGATCGTTCTGAATGGGCCGACGGGGGTTGGAT
AA

Upstream 100 bases:

>100_bases
GGACCGATGTGGCCTTTTTCGAACCGGAGTGTGACCTGCCCACGTAAAGCGTCGAGCGAGAAGAACCGTGGCTTGTCGCA
CCATTGATGCGTCAAATGTC

Downstream 100 bases:

>100_bases
CTTTCCATGCAATGCGGATCGATGGGCGCAGGTTGTAGATGAACACGTTGTGATCCATTTCATTTGTGGTCGCTCGCGGA
TAAAATTCATGTTTGGTTCC

Product: histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 533; Mature: 533

Protein sequence:

>533_residues
MDTNLTVTTIRSGAHRITDHQDDIFFAAVSTTRMPMVVTDPHLPDHPVIFANHAFLRMTGYELTEIIGSNCRFLQGPETD
RATIDEVRAAVADRRELATEILNYRKDGSTFWNALFISPVFNEQGELVYFFGSQLDVSRRRDAEDALHQAQKMEALGQLT
GGIAHDFNNLLQVMAGYVDVLQMGIEGHAQSAVMAQSLDRIRGAVAKATTLTQQLLAFARKQKLVGRTVNLNTLADGMVE
LARRTLGGNISLKTEYEEGLGNCRVDSTQLEVALLNVLLNARDALASRRDGVVTVRTETVELEQQETVGFADLRSGCYVT
IAISDNGCGIPPEILDRVMDPFFTTKGEGKGTGLGLSMVYGFAKQSGGAVNLYSEPGVGTTLRLYFPAVGGIAQRRPSAP
KAIEKAGNEMILIVDDRVEVAEVAQAMLEQIGYRTRVVLNTKEAMDILQEGAHLDLLFTDLIMPGNMNGVMLAREARRLH
PKIKVLLTTGYADASMERTDANGSEFDIIHKPYRRAELARKVRIVLNGPTGVG

Sequences:

>Translated_533_residues
MDTNLTVTTIRSGAHRITDHQDDIFFAAVSTTRMPMVVTDPHLPDHPVIFANHAFLRMTGYELTEIIGSNCRFLQGPETD
RATIDEVRAAVADRRELATEILNYRKDGSTFWNALFISPVFNEQGELVYFFGSQLDVSRRRDAEDALHQAQKMEALGQLT
GGIAHDFNNLLQVMAGYVDVLQMGIEGHAQSAVMAQSLDRIRGAVAKATTLTQQLLAFARKQKLVGRTVNLNTLADGMVE
LARRTLGGNISLKTEYEEGLGNCRVDSTQLEVALLNVLLNARDALASRRDGVVTVRTETVELEQQETVGFADLRSGCYVT
IAISDNGCGIPPEILDRVMDPFFTTKGEGKGTGLGLSMVYGFAKQSGGAVNLYSEPGVGTTLRLYFPAVGGIAQRRPSAP
KAIEKAGNEMILIVDDRVEVAEVAQAMLEQIGYRTRVVLNTKEAMDILQEGAHLDLLFTDLIMPGNMNGVMLAREARRLH
PKIKVLLTTGYADASMERTDANGSEFDIIHKPYRRAELARKVRIVLNGPTGVG
>Mature_533_residues
MDTNLTVTTIRSGAHRITDHQDDIFFAAVSTTRMPMVVTDPHLPDHPVIFANHAFLRMTGYELTEIIGSNCRFLQGPETD
RATIDEVRAAVADRRELATEILNYRKDGSTFWNALFISPVFNEQGELVYFFGSQLDVSRRRDAEDALHQAQKMEALGQLT
GGIAHDFNNLLQVMAGYVDVLQMGIEGHAQSAVMAQSLDRIRGAVAKATTLTQQLLAFARKQKLVGRTVNLNTLADGMVE
LARRTLGGNISLKTEYEEGLGNCRVDSTQLEVALLNVLLNARDALASRRDGVVTVRTETVELEQQETVGFADLRSGCYVT
IAISDNGCGIPPEILDRVMDPFFTTKGEGKGTGLGLSMVYGFAKQSGGAVNLYSEPGVGTTLRLYFPAVGGIAQRRPSAP
KAIEKAGNEMILIVDDRVEVAEVAQAMLEQIGYRTRVVLNTKEAMDILQEGAHLDLLFTDLIMPGNMNGVMLAREARRLH
PKIKVLLTTGYADASMERTDANGSEFDIIHKPYRRAELARKVRIVLNGPTGVG

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Homo sapiens, GI6912446, Length=95, Percent_Identity=38.9473684210526, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI38569493, Length=98, Percent_Identity=33.6734693877551, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI27886667, Length=94, Percent_Identity=31.9148936170213, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1788549, Length=271, Percent_Identity=29.1512915129151, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI1790436, Length=266, Percent_Identity=30.0751879699248, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1790300, Length=255, Percent_Identity=28.6274509803922, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI87081816, Length=210, Percent_Identity=27.1428571428571, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI48994928, Length=230, Percent_Identity=28.2608695652174, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788713, Length=441, Percent_Identity=22.6757369614512, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI145693157, Length=368, Percent_Identity=23.9130434782609, Blast_Score=63, Evalue=5e-11,
Organism=Drosophila melanogaster, GI17136946, Length=98, Percent_Identity=29.5918367346939, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 58412; Mature: 58412

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTNLTVTTIRSGAHRITDHQDDIFFAAVSTTRMPMVVTDPHLPDHPVIFANHAFLRMTG
CCCCEEEEEECCCCHHCCCCCCCEEEEEEECCCCCEEEECCCCCCCCEEEECCEEEEECC
YELTEIIGSNCRFLQGPETDRATIDEVRAAVADRRELATEILNYRKDGSTFWNALFISPV
HHHHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHEEEEECC
FNEQGELVYFFGSQLDVSRRRDAEDALHQAQKMEALGQLTGGIAHDFNNLLQVMAGYVDV
CCCCCCEEEEECCCCCCHHCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH
LQMGIEGHAQSAVMAQSLDRIRGAVAKATTLTQQLLAFARKQKLVGRTVNLNTLADGMVE
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHH
LARRTLGGNISLKTEYEEGLGNCRVDSTQLEVALLNVLLNARDALASRRDGVVTVRTETV
HHHHHCCCCEEEEECHHHCCCCCEECHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEE
ELEQQETVGFADLRSGCYVTIAISDNGCGIPPEILDRVMDPFFTTKGEGKGTGLGLSMVY
EECHHHCCCHHHHCCCCEEEEEECCCCCCCCHHHHHHHHCHHHCCCCCCCCCCCHHHHHH
GFAKQSGGAVNLYSEPGVGTTLRLYFPAVGGIAQRRPSAPKAIEKAGNEMILIVDDRVEV
HHHHCCCCEEEEECCCCCCCEEEEEECCCCCHHHCCCCCCHHHHHCCCCEEEEEECCCCH
AEVAQAMLEQIGYRTRVVLNTKEAMDILQEGAHLDLLFTDLIMPGNMNGVMLAREARRLH
HHHHHHHHHHCCCCEEEEEECHHHHHHHHCCCCEEEEEEHHCCCCCCCCEEEEHHHHHCC
PKIKVLLTTGYADASMERTDANGSEFDIIHKPYRRAELARKVRIVLNGPTGVG
CEEEEEEEECCCCCCCCCCCCCCCEEEEECCCHHHHHHHHEEEEEEECCCCCC
>Mature Secondary Structure
MDTNLTVTTIRSGAHRITDHQDDIFFAAVSTTRMPMVVTDPHLPDHPVIFANHAFLRMTG
CCCCEEEEEECCCCHHCCCCCCCEEEEEEECCCCCEEEECCCCCCCCEEEECCEEEEECC
YELTEIIGSNCRFLQGPETDRATIDEVRAAVADRRELATEILNYRKDGSTFWNALFISPV
HHHHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHEEEEECC
FNEQGELVYFFGSQLDVSRRRDAEDALHQAQKMEALGQLTGGIAHDFNNLLQVMAGYVDV
CCCCCCEEEEECCCCCCHHCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH
LQMGIEGHAQSAVMAQSLDRIRGAVAKATTLTQQLLAFARKQKLVGRTVNLNTLADGMVE
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHH
LARRTLGGNISLKTEYEEGLGNCRVDSTQLEVALLNVLLNARDALASRRDGVVTVRTETV
HHHHHCCCCEEEEECHHHCCCCCEECHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEE
ELEQQETVGFADLRSGCYVTIAISDNGCGIPPEILDRVMDPFFTTKGEGKGTGLGLSMVY
EECHHHCCCHHHHCCCCEEEEEECCCCCCCCHHHHHHHHCHHHCCCCCCCCCCCHHHHHH
GFAKQSGGAVNLYSEPGVGTTLRLYFPAVGGIAQRRPSAPKAIEKAGNEMILIVDDRVEV
HHHHCCCCEEEEECCCCCCCEEEEEECCCCCHHHCCCCCCHHHHHCCCCEEEEEECCCCH
AEVAQAMLEQIGYRTRVVLNTKEAMDILQEGAHLDLLFTDLIMPGNMNGVMLAREARRLH
HHHHHHHHHHCCCCEEEEEECHHHHHHHHCCCCEEEEEEHHCCCCCCCCEEEEHHHHHCC
PKIKVLLTTGYADASMERTDANGSEFDIIHKPYRRAELARKVRIVLNGPTGVG
CEEEEEEEECCCCCCCCCCCCCCCEEEEECCCHHHHHHHHEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA