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The map label for this gene is cysH1 [H]

Identifier: 186476984

GI number: 186476984

Start: 2505919

End: 2506659

Strand: Reverse

Name: cysH1 [H]

Synonym: Bphy_2233

Alternate gene names: 186476984

Gene position: 2506659-2505919 (Counterclockwise)

Preceding gene: 186476985

Following gene: 186476983

Centisome position: 72.05

GC content: 63.97

Gene sequence:

>741_bases
ATGACGGACGCTGCCGCTCTCACGCCCGAGCTTCAGGCGAAGATCGAGCGTCTCGACGCGCTGCTCGATACGATCGGCCA
GCGTCACGAGGCGGTCAAGTTCGCCAGCAGCCTCGCAGCCGAAGACATGCTGCTGACGCACGCAATTCTGTCCCGCGGCG
TCAAGATTGGCATCTTCTCCCTTAATACGGGTCGCCTTCATGCGGAAACGCTCGGTATGATCGAGCGCGTGCGCGAACGC
TATGGATACGACATCGAACAGTTTCATCCGCAAGCGGCCGCGGTCGACGAATACGTCGCGCAGCATGGCTTGAATGCGTT
CTACGAAAGCATCGACCTGCGCAAGCGGTGCTGCGAAATCCGCAAGGTCGAGCCGCTGAACCGCGCGCTTGCCGACGTCG
GCGCATGGGTCACCGGTCAGCGTCGCGAGCAGTCGGTGACGCGTGCGGAACTGCACGAGGAAGAGCACGACGGCGCGCGC
AACATCGCGAAGTACAACCCGCTCGCCGACTGGACGGAAGCCGACGTATGGGCTTACCTGAAGGCGTTCGACGTGCCCGT
GAATCCGCTGCATGCACGCGGCTATCCGAGCATCGGCTGCGAGCCGTGCACGCGGGCCGTGCGCCCTGGCGAAGACAGCC
GGGCAGGGCGCTGGTGGTGGGAATCGCGCGACACGAAGGAATGCGGTTTGCACATTACGACGATCCCGGTGACGGTGATC
GGCGAGAACGCCTCGGCCTGA

Upstream 100 bases:

>100_bases
CATTCACCGAATTCACCGTGCAATACCAGGGTGCGTTCGACGATCCGTCGCCGCTGTTCCGTCGGCGCGAAGCGGCCGCT
GCTGCGCAAAAGGCCACGGC

Downstream 100 bases:

>100_bases
TGTGCATCCCCACGCCGACGACGCAGATTTCGATTGAATCTTTACGTGTCGCATGCATCGGGTGAGAGCCCGACCATGCG
ACACGAACCAACGAAGGACC

Product: phosphoadenosine phosphosulfate reductase

Products: NA

Alternate protein names: 3'-phosphoadenylylsulfate reductase; PAPS reductase, thioredoxin dependent; PAPS sulfotransferase; PAdoPS reductase [H]

Number of amino acids: Translated: 246; Mature: 245

Protein sequence:

>246_residues
MTDAAALTPELQAKIERLDALLDTIGQRHEAVKFASSLAAEDMLLTHAILSRGVKIGIFSLNTGRLHAETLGMIERVRER
YGYDIEQFHPQAAAVDEYVAQHGLNAFYESIDLRKRCCEIRKVEPLNRALADVGAWVTGQRREQSVTRAELHEEEHDGAR
NIAKYNPLADWTEADVWAYLKAFDVPVNPLHARGYPSIGCEPCTRAVRPGEDSRAGRWWWESRDTKECGLHITTIPVTVI
GENASA

Sequences:

>Translated_246_residues
MTDAAALTPELQAKIERLDALLDTIGQRHEAVKFASSLAAEDMLLTHAILSRGVKIGIFSLNTGRLHAETLGMIERVRER
YGYDIEQFHPQAAAVDEYVAQHGLNAFYESIDLRKRCCEIRKVEPLNRALADVGAWVTGQRREQSVTRAELHEEEHDGAR
NIAKYNPLADWTEADVWAYLKAFDVPVNPLHARGYPSIGCEPCTRAVRPGEDSRAGRWWWESRDTKECGLHITTIPVTVI
GENASA
>Mature_245_residues
TDAAALTPELQAKIERLDALLDTIGQRHEAVKFASSLAAEDMLLTHAILSRGVKIGIFSLNTGRLHAETLGMIERVRERY
GYDIEQFHPQAAAVDEYVAQHGLNAFYESIDLRKRCCEIRKVEPLNRALADVGAWVTGQRREQSVTRAELHEEEHDGARN
IAKYNPLADWTEADVWAYLKAFDVPVNPLHARGYPSIGCEPCTRAVRPGEDSRAGRWWWESRDTKECGLHITTIPVTVIG
ENASA

Specific function: Reduction of activated sulfate into sulfite [H]

COG id: COG0175

COG function: function code EH; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAPS reductase family. CysH subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789121, Length=231, Percent_Identity=29.004329004329, Blast_Score=78, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6325425, Length=114, Percent_Identity=42.1052631578947, Blast_Score=83, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011798
- InterPro:   IPR004511
- InterPro:   IPR002500
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01507 PAPS_reduct [H]

EC number: =1.8.4.8 [H]

Molecular weight: Translated: 27560; Mature: 27429

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDAAALTPELQAKIERLDALLDTIGQRHEAVKFASSLAAEDMLLTHAILSRGVKIGIFS
CCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
LNTGRLHAETLGMIERVRERYGYDIEQFHPQAAAVDEYVAQHGLNAFYESIDLRKRCCEI
ECCCCHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RKVEPLNRALADVGAWVTGQRREQSVTRAELHEEEHDGARNIAKYNPLADWTEADVWAYL
HCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCHHHHHHHHH
KAFDVPVNPLHARGYPSIGCEPCTRAVRPGEDSRAGRWWWESRDTKECGLHITTIPVTVI
HHHCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCHHHCEEEEEEEEEEE
GENASA
CCCCCC
>Mature Secondary Structure 
TDAAALTPELQAKIERLDALLDTIGQRHEAVKFASSLAAEDMLLTHAILSRGVKIGIFS
CCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
LNTGRLHAETLGMIERVRERYGYDIEQFHPQAAAVDEYVAQHGLNAFYESIDLRKRCCEI
ECCCCHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RKVEPLNRALADVGAWVTGQRREQSVTRAELHEEEHDGARNIAKYNPLADWTEADVWAYL
HCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCHHHHHHHHH
KAFDVPVNPLHARGYPSIGCEPCTRAVRPGEDSRAGRWWWESRDTKECGLHITTIPVTVI
HHHCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCHHHCEEEEEEEEEEE
GENASA
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10710307 [H]