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The map label for this gene is fecD [C]

Identifier: 186476963

GI number: 186476963

Start: 2485512

End: 2486561

Strand: Reverse

Name: fecD [C]

Synonym: Bphy_2212

Alternate gene names: 186476963

Gene position: 2486561-2485512 (Counterclockwise)

Preceding gene: 186476964

Following gene: 186476962

Centisome position: 71.47

GC content: 69.24

Gene sequence:

>1050_bases
ATGAGCGGCGTCGTACCACGTCAACGACTGCGGTCCGCGCGCGGCATGAGCGCTAAGCGTGCGCTCATCATCTGGTCTGC
CCTTGCGTTTGCCGCGCTCGCCGTGTTCGTCGCGTCGCTTGCGTTGGGCAGCGTGAGCGTCACCCCGCGGCAGGTGTTCG
ATGCATTGCTGCCGACGCAAGATGGATCGTCCGATCTCGTCGTGCAGATCGTACGCACGCTGCGCCTGCCGCGCTCGCTC
GCGGGCTTCGGCTGCGGGGCGCTGCTCGCGCTCGCGGGCGCGTTGCTTCAGGTATTGCTGCGCAATCCGCTTGCCGAGCC
GTATGTGCTCGGCGTATCGGGCGGCGCAGCAAGCTTCGCGCTCGTTGCGATGATTGCGGGCTGCGCGTGGTGGCTCGTCG
ATGCTTGCGCGTTCGCGGGTGCGTTCGCGTCGATTTTGCTGGTGCTCGGTCTTGCACGCGGTGCGCTGTGGCGCGGCGAG
CCGCAGGATGCCTCGCCGCGGCTCTTGCTGACGGGTGCCGTCATCGCGGCCGGGTGGGGCGCCATCATTACCTTGCTGCT
GACGGTCGCACCCGAGAGCCGCTTGCGCGGCATGCTGTTCTGGCTGACGGGCGATCTGAATGGCGGCGGCATGCCGTGGC
TTGCGCTCGCGGCGCTGTGCGTGGCGTTGATCGCGATCGCGCCCGTCGCGCCGCAACTGAACGTGCTGCTGCGCGGCGAT
GCCGCGGCGCAGGCGCTCGGCGTGCAAGTGTCGCGCACGCGGCTGCGCGTCTATCTGGTTGCGTCGCTCGCGGCGGCCGT
TGCCGTGACGACGGGCGGCACGATCGGTTTCGTCGGTCTCGTCGTGCCGCACGTGTTGCGCCTCGCGTTCGGCAACGATC
AGCGAATGCTGCTGCCTGCGGCTGCGCTCGGCGGGGGCGTCGCGGTGATGGCCGCCGACCTGATTGCGCGCACCGTGATC
GCGCCCGCGCAATTGCCCGTCGGCGTGATCACCGCGCTGATCGGCGTGCCCTTGTTCCTGTGGATGTTGCTGCGACGGAG
GCACGCATGA

Upstream 100 bases:

>100_bases
CCAGAATCTCTTCGACAAGGACTATGAACTCGCCTACACGTACAACACGCCGCGACGTGGCGCTTACCTCGCGCTCGGCT
GGCAGCAACAGTAACCGACG

Downstream 100 bases:

>100_bases
ACACCCGCGGTCCCGCCGACATCACATTGCGCGCCGATCAACTCACGCTGCGCGCCGGCGCGCGCACGCTGCTCGCCAAC
TTCACGCACACGTTCTATCC

Product: transport system permease

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MSGVVPRQRLRSARGMSAKRALIIWSALAFAALAVFVASLALGSVSVTPRQVFDALLPTQDGSSDLVVQIVRTLRLPRSL
AGFGCGALLALAGALLQVLLRNPLAEPYVLGVSGGAASFALVAMIAGCAWWLVDACAFAGAFASILLVLGLARGALWRGE
PQDASPRLLLTGAVIAAGWGAIITLLLTVAPESRLRGMLFWLTGDLNGGGMPWLALAALCVALIAIAPVAPQLNVLLRGD
AAAQALGVQVSRTRLRVYLVASLAAAVAVTTGGTIGFVGLVVPHVLRLAFGNDQRMLLPAAALGGGVAVMAADLIARTVI
APAQLPVGVITALIGVPLFLWMLLRRRHA

Sequences:

>Translated_349_residues
MSGVVPRQRLRSARGMSAKRALIIWSALAFAALAVFVASLALGSVSVTPRQVFDALLPTQDGSSDLVVQIVRTLRLPRSL
AGFGCGALLALAGALLQVLLRNPLAEPYVLGVSGGAASFALVAMIAGCAWWLVDACAFAGAFASILLVLGLARGALWRGE
PQDASPRLLLTGAVIAAGWGAIITLLLTVAPESRLRGMLFWLTGDLNGGGMPWLALAALCVALIAIAPVAPQLNVLLRGD
AAAQALGVQVSRTRLRVYLVASLAAAVAVTTGGTIGFVGLVVPHVLRLAFGNDQRMLLPAAALGGGVAVMAADLIARTVI
APAQLPVGVITALIGVPLFLWMLLRRRHA
>Mature_348_residues
SGVVPRQRLRSARGMSAKRALIIWSALAFAALAVFVASLALGSVSVTPRQVFDALLPTQDGSSDLVVQIVRTLRLPRSLA
GFGCGALLALAGALLQVLLRNPLAEPYVLGVSGGAASFALVAMIAGCAWWLVDACAFAGAFASILLVLGLARGALWRGEP
QDASPRLLLTGAVIAAGWGAIITLLLTVAPESRLRGMLFWLTGDLNGGGMPWLALAALCVALIAIAPVAPQLNVLLRGDA
AAQALGVQVSRTRLRVYLVASLAAAVAVTTGGTIGFVGLVVPHVLRLAFGNDQRMLLPAAALGGGVAVMAADLIARTVIA
PAQLPVGVITALIGVPLFLWMLLRRRHA

Specific function: Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=333, Percent_Identity=36.6366366366366, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1788004, Length=281, Percent_Identity=38.0782918149466, Blast_Score=130, Evalue=9e-32,
Organism=Escherichia coli, GI1790741, Length=339, Percent_Identity=35.1032448377581, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1786347, Length=278, Percent_Identity=31.294964028777, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1786805, Length=316, Percent_Identity=36.3924050632911, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1786804, Length=324, Percent_Identity=37.037037037037, Blast_Score=91, Evalue=9e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 35942; Mature: 35810

Theoretical pI: Translated: 12.01; Mature: 12.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGVVPRQRLRSARGMSAKRALIIWSALAFAALAVFVASLALGSVSVTPRQVFDALLPTQ
CCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCC
DGSSDLVVQIVRTLRLPRSLAGFGCGALLALAGALLQVLLRNPLAEPYVLGVSGGAASFA
CCCHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHH
LVAMIAGCAWWLVDACAFAGAFASILLVLGLARGALWRGEPQDASPRLLLTGAVIAAGWG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEHHHHHHHHH
AIITLLLTVAPESRLRGMLFWLTGDLNGGGMPWLALAALCVALIAIAPVAPQLNVLLRGD
HHHHHHHHHCCHHHHCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECC
AAAQALGVQVSRTRLRVYLVASLAAAVAVTTGGTIGFVGLVVPHVLRLAFGNDQRMLLPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEEEH
AALGGGVAVMAADLIARTVIAPAQLPVGVITALIGVPLFLWMLLRRRHA
HHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SGVVPRQRLRSARGMSAKRALIIWSALAFAALAVFVASLALGSVSVTPRQVFDALLPTQ
CCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCC
DGSSDLVVQIVRTLRLPRSLAGFGCGALLALAGALLQVLLRNPLAEPYVLGVSGGAASFA
CCCHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHH
LVAMIAGCAWWLVDACAFAGAFASILLVLGLARGALWRGEPQDASPRLLLTGAVIAAGWG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEHHHHHHHHH
AIITLLLTVAPESRLRGMLFWLTGDLNGGGMPWLALAALCVALIAIAPVAPQLNVLLRGD
HHHHHHHHHCCHHHHCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECC
AAAQALGVQVSRTRLRVYLVASLAAAVAVTTGGTIGFVGLVVPHVLRLAFGNDQRMLLPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEEEH
AALGGGVAVMAADLIARTVIAPAQLPVGVITALIGVPLFLWMLLRRRHA
HHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]