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The map label for this gene is cobQ

Identifier: 186476954

GI number: 186476954

Start: 2477214

End: 2478668

Strand: Reverse

Name: cobQ

Synonym: Bphy_2203

Alternate gene names: 186476954

Gene position: 2478668-2477214 (Counterclockwise)

Preceding gene: 186476959

Following gene: 186476953

Centisome position: 71.24

GC content: 67.84

Gene sequence:

>1455_bases
ATGATTCAAGGCACGACTTCCGACGCGGGCAAGAGCACGCTCGTCGCCGGTCTATGCCGTCTCGCGCGGCGCGCGGGCGT
GCGGGTTGCGCCGTTCAAGCCGCAGAACATGGCCCTGAACAGCGCGGTGACGATAGACGGCGGCGAGATCGGCCGTGCGC
AGGCGTTGCAGGCGGTGGCGGCGGGCATCGACGCGCATACCGATCTGAACCCGGTGCTGCTCAAGCCGACCAGCGACCGC
GGCGCGCAAGTGATCATCCACGGCAAGGCGCGCATGAATCTCGACGCGCGTGCGTATCACGACTACAAGCCTGTCGCGTT
CGAGGCCGTGCTGGCGTCGTATGCGCGGCTGAAGGCGTCGTACGACACGATCTTCGTCGAAGGCGCGGGCAGTCCCGCCG
AAATCAATCTGCGCGAACGCGATATCGCGAACATGGGCTTTGCGGAGGCGGTGGATTGCCCCGTCGTGCTCGTCTCCGAT
ATCGATCGCGGCGGCGTGTTCGCGCATCTGACGGGCACGCTGGCGTGTCTGTCCGACAGTGAACAGGCGCGCGTGCGCGG
TTTCGTGATCAACCGCTTTCGCGGCGACGTGAGCTTGTTGCAGCCGGGGCTCGACTGGCTCGAGGCGAAGACGGGCAAGC
CCGTGCTCGGCGTCGTGCCGTATCTGCATGGCCTCACGCTCGATGCCGAAGACATGCTGCCGCGGGAATTGCGCGCCGCG
CAGGCGAGTGCGGACGCGCTGCGCGTCGTCGTGCCCGCGCTGCCGCACATCAGCAATCACACGGATTTCGACGCACTGCG
TGCGCATCCGCAAGTCGACTTCCACTATGTCCGCGCGGGCAGCGCGCCGCCGCCCGCCGATCTGATCATCTTGCCGGGGT
CGAAGAACGTGCAGGGCGACCTGGCGTTCCTGCGCGCGCAAGGTTGGGACGCCGTGCTCCAGCGCCATCTGCGTTACGGC
GGACGTGTGATCGGCATTTGCGGCGGCATGCAGATGCTCGGCCGCGAAGTGGCCGATCCGTATGGCGTGGAAGGCCCGCC
CGGGACGGTCGAGGGGCTCGGCTGGCTCGACTTCTCGACGACGCTCACCCGCGACAAGACGCTGAAGAACGTAACGGGAC
GGCTGGCGACGGACGCGGGCCGCATCGCGGGCTATGAGATCCACATGGGCGAAACGCAAGGGCCCGCGCTCGACGCGCCT
GCGCTGCTGCTCGCCGACGAAATGGGCGGCGTGCGTCCCGACGGCGCCCGTTCCGCCGACGGCCAGATCCTCGCCACCTA
CGTGCACGGCCTGTTCGACACGCCGGCCGCCTGCGCGTCGCTACTGGCGTGGGCCGGGCTGAAAAACGCCGATGCGATCG
ACTATCCGGCGCTGCGCGAAGCGTCGCTGGAGCGCCTCGCCGACACGCTCGCCGTACATCTCGATCTGAAGCGTTTCTGG
GAGGCTATCGGCTGA

Upstream 100 bases:

>100_bases
ATAATGCGGGCTTCCCTTTTTTCCGCTTGCGCTCGTGGCCACCGTGTCCGCTTCACTCAACTCTTCGCCTGATTCCCCAG
ACGTGCCACGCGGCACGCTG

Downstream 100 bases:

>100_bases
TTCGTTCTTGAGGAGAATTAATGTAAGTCATTCAGGCGATTTTTCGACCGCTACGGTTCGAATACAGTCCGTTCCATCGA
CGACGCAGCCCGCGCCGTCA

Product: cobyric acid synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 484; Mature: 484

Protein sequence:

>484_residues
MIQGTTSDAGKSTLVAGLCRLARRAGVRVAPFKPQNMALNSAVTIDGGEIGRAQALQAVAAGIDAHTDLNPVLLKPTSDR
GAQVIIHGKARMNLDARAYHDYKPVAFEAVLASYARLKASYDTIFVEGAGSPAEINLRERDIANMGFAEAVDCPVVLVSD
IDRGGVFAHLTGTLACLSDSEQARVRGFVINRFRGDVSLLQPGLDWLEAKTGKPVLGVVPYLHGLTLDAEDMLPRELRAA
QASADALRVVVPALPHISNHTDFDALRAHPQVDFHYVRAGSAPPPADLIILPGSKNVQGDLAFLRAQGWDAVLQRHLRYG
GRVIGICGGMQMLGREVADPYGVEGPPGTVEGLGWLDFSTTLTRDKTLKNVTGRLATDAGRIAGYEIHMGETQGPALDAP
ALLLADEMGGVRPDGARSADGQILATYVHGLFDTPAACASLLAWAGLKNADAIDYPALREASLERLADTLAVHLDLKRFW
EAIG

Sequences:

>Translated_484_residues
MIQGTTSDAGKSTLVAGLCRLARRAGVRVAPFKPQNMALNSAVTIDGGEIGRAQALQAVAAGIDAHTDLNPVLLKPTSDR
GAQVIIHGKARMNLDARAYHDYKPVAFEAVLASYARLKASYDTIFVEGAGSPAEINLRERDIANMGFAEAVDCPVVLVSD
IDRGGVFAHLTGTLACLSDSEQARVRGFVINRFRGDVSLLQPGLDWLEAKTGKPVLGVVPYLHGLTLDAEDMLPRELRAA
QASADALRVVVPALPHISNHTDFDALRAHPQVDFHYVRAGSAPPPADLIILPGSKNVQGDLAFLRAQGWDAVLQRHLRYG
GRVIGICGGMQMLGREVADPYGVEGPPGTVEGLGWLDFSTTLTRDKTLKNVTGRLATDAGRIAGYEIHMGETQGPALDAP
ALLLADEMGGVRPDGARSADGQILATYVHGLFDTPAACASLLAWAGLKNADAIDYPALREASLERLADTLAVHLDLKRFW
EAIG
>Mature_484_residues
MIQGTTSDAGKSTLVAGLCRLARRAGVRVAPFKPQNMALNSAVTIDGGEIGRAQALQAVAAGIDAHTDLNPVLLKPTSDR
GAQVIIHGKARMNLDARAYHDYKPVAFEAVLASYARLKASYDTIFVEGAGSPAEINLRERDIANMGFAEAVDCPVVLVSD
IDRGGVFAHLTGTLACLSDSEQARVRGFVINRFRGDVSLLQPGLDWLEAKTGKPVLGVVPYLHGLTLDAEDMLPRELRAA
QASADALRVVVPALPHISNHTDFDALRAHPQVDFHYVRAGSAPPPADLIILPGSKNVQGDLAFLRAQGWDAVLQRHLRYG
GRVIGICGGMQMLGREVADPYGVEGPPGTVEGLGWLDFSTTLTRDKTLKNVTGRLATDAGRIAGYEIHMGETQGPALDAP
ALLLADEMGGVRPDGARSADGQILATYVHGLFDTPAACASLLAWAGLKNADAIDYPALREASLERLADTLAVHLDLKRFW
EAIG

Specific function: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation

COG id: COG1492

COG function: function code H; Cobyric acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GATase cobBQ-type domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COBQ_BURP8 (B2JER3)

Other databases:

- EMBL:   CP001043
- RefSeq:   YP_001858424.1
- ProteinModelPortal:   B2JER3
- GeneID:   6243689
- GenomeReviews:   CP001043_GR
- KEGG:   bph:Bphy_2203
- HOGENOM:   HBG302271
- OMA:   AHTDLNP
- ProtClustDB:   PRK00784
- HAMAP:   MF_00028
- InterPro:   IPR002586
- InterPro:   IPR017929
- InterPro:   IPR004459
- InterPro:   IPR011698
- TIGRFAMs:   TIGR00313

Pfam domain/function: PF01656 CbiA; PF07685 GATase_3

EC number: NA

Molecular weight: Translated: 51489; Mature: 51489

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: PS51274 GATASE_COBBQ

Important sites: ACT_SITE 327-327 ACT_SITE 429-429

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQGTTSDAGKSTLVAGLCRLARRAGVRVAPFKPQNMALNSAVTIDGGEIGRAQALQAVA
CCCCCCCCCCHHHHHHHHHHHHHHCCCEECCCCCCCCEECCEEEECCCCCCHHHHHHHHH
AGIDAHTDLNPVLLKPTSDRGAQVIIHGKARMNLDARAYHDYKPVAFEAVLASYARLKAS
HCCCCCCCCCCEEEECCCCCCCEEEEECCEEECCCHHHHCCCCCHHHHHHHHHHHHHHCC
YDTIFVEGAGSPAEINLRERDIANMGFAEAVDCPVVLVSDIDRGGVFAHLTGTLACLSDS
CCEEEEECCCCCCEEEEHHHHHHCCCCHHHCCCCEEEEECCCCCCEEEEEEEEEEEECCC
EQARVRGFVINRFRGDVSLLQPGLDWLEAKTGKPVLGVVPYLHGLTLDAEDMLPRELRAA
CHHHHHHEEEEHHCCCHHHHHCCHHHHHCCCCCCHHHHHHHHHCCCCCHHHCCHHHHHHH
QASADALRVVVPALPHISNHTDFDALRAHPQVDFHYVRAGSAPPPADLIILPGSKNVQGD
HHCHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCEEEEECCCCCCCCCEEEECCCCCCCCC
LAFLRAQGWDAVLQRHLRYGGRVIGICGGMQMLGREVADPYGVEGPPGTVEGLGWLDFST
EEEEECCCHHHHHHHHHHHCCEEEEEECCHHHHHHHHCCCCCCCCCCCCCCCCEEEECCC
TLTRDKTLKNVTGRLATDAGRIAGYEIHMGETQGPALDAPALLLADEMGGVRPDGARSAD
HHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCHHEEEHHHCCCCCCCCCCCC
GQILATYVHGLFDTPAACASLLAWAGLKNADAIDYPALREASLERLADTLAVHLDLKRFW
CCCHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EAIG
HHCC
>Mature Secondary Structure
MIQGTTSDAGKSTLVAGLCRLARRAGVRVAPFKPQNMALNSAVTIDGGEIGRAQALQAVA
CCCCCCCCCCHHHHHHHHHHHHHHCCCEECCCCCCCCEECCEEEECCCCCCHHHHHHHHH
AGIDAHTDLNPVLLKPTSDRGAQVIIHGKARMNLDARAYHDYKPVAFEAVLASYARLKAS
HCCCCCCCCCCEEEECCCCCCCEEEEECCEEECCCHHHHCCCCCHHHHHHHHHHHHHHCC
YDTIFVEGAGSPAEINLRERDIANMGFAEAVDCPVVLVSDIDRGGVFAHLTGTLACLSDS
CCEEEEECCCCCCEEEEHHHHHHCCCCHHHCCCCEEEEECCCCCCEEEEEEEEEEEECCC
EQARVRGFVINRFRGDVSLLQPGLDWLEAKTGKPVLGVVPYLHGLTLDAEDMLPRELRAA
CHHHHHHEEEEHHCCCHHHHHCCHHHHHCCCCCCHHHHHHHHHCCCCCHHHCCHHHHHHH
QASADALRVVVPALPHISNHTDFDALRAHPQVDFHYVRAGSAPPPADLIILPGSKNVQGD
HHCHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCEEEEECCCCCCCCCEEEECCCCCCCCC
LAFLRAQGWDAVLQRHLRYGGRVIGICGGMQMLGREVADPYGVEGPPGTVEGLGWLDFST
EEEEECCCHHHHHHHHHHHCCEEEEEECCHHHHHHHHCCCCCCCCCCCCCCCCEEEECCC
TLTRDKTLKNVTGRLATDAGRIAGYEIHMGETQGPALDAPALLLADEMGGVRPDGARSAD
HHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCHHEEEHHHCCCCCCCCCCCC
GQILATYVHGLFDTPAACASLLAWAGLKNADAIDYPALREASLERLADTLAVHLDLKRFW
CCCHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EAIG
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA