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The map label for this gene is uup-A [H]

Identifier: 186476878

GI number: 186476878

Start: 2388227

End: 2390152

Strand: Reverse

Name: uup-A [H]

Synonym: Bphy_2125

Alternate gene names: 186476878

Gene position: 2390152-2388227 (Counterclockwise)

Preceding gene: 186476879

Following gene: 186476877

Centisome position: 68.7

GC content: 64.8

Gene sequence:

>1926_bases
ATGTCGCTTTACACCATTACGGGCGCGCAACTGGCGTTCGGCCATGTCGCGCTGCTCGATCACGCGGATTTTTCACTCGA
AGCCGGCGAGCGCGTCGGGTTGATCGGCCGTAACGGCGCGGGCAAGTCGTCGCTGCTGAAAATCGTCGCGGAGCTGGCGA
GGCCGGACGACGGCCTGATCACGCGCCAGCAGGATCTCGTCACCGTGTACGTGCCACAGGAACCCGAGTTCGACGGCGAC
GTTACAGTCTTCGATACGGTGGCGGCAGGTCTCACGCGCGCGAGCGCGCTGCTCGACGAATACAACACGGTCGCGCACGA
ACTGGCGGAAACGCCTGAGGGCGCGCAGCACGACGCGTTGCTCGCGCGCATGAACGCGCTGCAATCGTCGCTCGATGCGA
CGGATGCCTGGAACTGGCGCACGCGCGTCGCCACAACCCTGGCGCAGATCGGTCTCGACGGCGATGCGCAGGTGGGCTCC
CTGTCGGGCGGCATGCAAAAGCGCGTCGCGCTGGCGCGCGCGCTCGTCGTGCAGCCCGACGTGCTGCTGCTCGACGAACC
GACCAACCATCTCGACTTCGACGGCATCCGCTGGCTGGAAGAGCTGCTGGTCTCGCAGCGTGCCGGTCTGCTGTTCATCA
CCCACGACCGCGCGTTTCTCGATCGCGTCGCGACGCGCATTGTCGAGCTGGATCGCGGGCGTCTGCTGTCGTATCCGGGC
AATTTCTCCGCGTATCAGACGCGCAAGGCGCAGCAGCTTGAAGTGGAGCGCGTCGAGAACGAGAAGTTCGACAAGCTTCT
CGCGCAGGAAGAAGTGTGGATCCGCAAGGGCGTCGAGGCGCGGCGCACGCGCAGCGTCGGCCGCATTGCGCGGCTCGTGC
AGATGCGTAAGGAGCGTGAAGAACGGCGCAACGTGCAGGGCAACGTCAAGCTCGACGTCGGACAGGGCGAGAAGTCCGGC
AAGATCGTCGCCGAACTCACGGACGTGACGAAGCGCTACGGCGAGCGCACCGTGGTCGACCGTTTTTCGACGACGGTCAT
GCGCGGCGACAAGATCGGTTTCGTCGGTCCGAATGGCGCGGGCAAAACGACGCTGCTCAAGCTGATCCTCGGCGAACTGC
AGCCGGACGACGGCGCGGTGCGTGTCGGCACCAACCTGCAGGTCGCTTACTTCGACCAGATGCGCGCGCAGCTCGATCTG
GAAAAGAGCCTCGCCGACACGATCAGCCCGGGTAGCGACTGGGTCGAGATCAACGGCCAGAAAAAGCACGTGATGAGCTA
TCTCGGCGACTTCCTGTTCGCGCCCGAGCGCGCGCGTTCGCCCGTCAAATCGCTGTCGGGCGGCGAGCGCAACCGCCTGC
TGCTGGCGCGTCTCTTTGCGCGGCCGGCCAACGTGCTGGTGCTCGACGAACCGACCAACGACCTCGACATTCCGACGCTC
GAACTGCTCGAGGAACTCCTGACGGACTACGACGGCACCGTGCTGCTGGTGAGCCACGACCGCGCGTTTCTCGACAACGT
GGTCACGTCGGTGATCGCTTCGGAAGACGCGGGCAAGTGGCGTGAATATGTCGGTGGCTTTACCGACTGGCAGATTCAGC
GCGAACGTTCGGAACAGATCGCGCAAAAGGATGCACCGAAAGAGCCGCCGAAGGAAGCCGCACCGAAGGAAAGCGCGGCG
GGTCGCAACGCGCAGCGCACGGTCAAGCTGTCGTTCAAGGAGCAGCGCGAACTCGAGGCGCTGCCCGAGCGGATCGCAGC
GCTGGAAGCGGAGCAGAAGGCGATCGGCGCGCAGATCGAGGAGGGCTCGATCTTCGTGAAGGACGCGCAGGAGGGGGCGC
GGCTGACAGAACGCTATGCGGCCATCGACGATGAATTGCTCGTGGCGATCGAGCGGTGGGATGAGTTGGAGAGCAAGAAG
AAGTAG

Upstream 100 bases:

>100_bases
TTCGTCCTATGACGTCTGCCCGTCCGCATCCCGTCAGCTCCCGCGCTGCCGACCGGTACAATGAGCGCTTCCGACTCATC
GCTGGTTTCTTCACTTTTCC

Downstream 100 bases:

>100_bases
CACGCCCATCGGTGTAGTACGCCTTTATACCAATCGTCCTACACCCCTCATCTAAATTGCCCCGCGCATCGAAATCAGTA
AAATACCCGCGGACCTGCTT

Product: ABC transporter-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 641; Mature: 640

Protein sequence:

>641_residues
MSLYTITGAQLAFGHVALLDHADFSLEAGERVGLIGRNGAGKSSLLKIVAELARPDDGLITRQQDLVTVYVPQEPEFDGD
VTVFDTVAAGLTRASALLDEYNTVAHELAETPEGAQHDALLARMNALQSSLDATDAWNWRTRVATTLAQIGLDGDAQVGS
LSGGMQKRVALARALVVQPDVLLLDEPTNHLDFDGIRWLEELLVSQRAGLLFITHDRAFLDRVATRIVELDRGRLLSYPG
NFSAYQTRKAQQLEVERVENEKFDKLLAQEEVWIRKGVEARRTRSVGRIARLVQMRKEREERRNVQGNVKLDVGQGEKSG
KIVAELTDVTKRYGERTVVDRFSTTVMRGDKIGFVGPNGAGKTTLLKLILGELQPDDGAVRVGTNLQVAYFDQMRAQLDL
EKSLADTISPGSDWVEINGQKKHVMSYLGDFLFAPERARSPVKSLSGGERNRLLLARLFARPANVLVLDEPTNDLDIPTL
ELLEELLTDYDGTVLLVSHDRAFLDNVVTSVIASEDAGKWREYVGGFTDWQIQRERSEQIAQKDAPKEPPKEAAPKESAA
GRNAQRTVKLSFKEQRELEALPERIAALEAEQKAIGAQIEEGSIFVKDAQEGARLTERYAAIDDELLVAIERWDELESKK
K

Sequences:

>Translated_641_residues
MSLYTITGAQLAFGHVALLDHADFSLEAGERVGLIGRNGAGKSSLLKIVAELARPDDGLITRQQDLVTVYVPQEPEFDGD
VTVFDTVAAGLTRASALLDEYNTVAHELAETPEGAQHDALLARMNALQSSLDATDAWNWRTRVATTLAQIGLDGDAQVGS
LSGGMQKRVALARALVVQPDVLLLDEPTNHLDFDGIRWLEELLVSQRAGLLFITHDRAFLDRVATRIVELDRGRLLSYPG
NFSAYQTRKAQQLEVERVENEKFDKLLAQEEVWIRKGVEARRTRSVGRIARLVQMRKEREERRNVQGNVKLDVGQGEKSG
KIVAELTDVTKRYGERTVVDRFSTTVMRGDKIGFVGPNGAGKTTLLKLILGELQPDDGAVRVGTNLQVAYFDQMRAQLDL
EKSLADTISPGSDWVEINGQKKHVMSYLGDFLFAPERARSPVKSLSGGERNRLLLARLFARPANVLVLDEPTNDLDIPTL
ELLEELLTDYDGTVLLVSHDRAFLDNVVTSVIASEDAGKWREYVGGFTDWQIQRERSEQIAQKDAPKEPPKEAAPKESAA
GRNAQRTVKLSFKEQRELEALPERIAALEAEQKAIGAQIEEGSIFVKDAQEGARLTERYAAIDDELLVAIERWDELESKK
K
>Mature_640_residues
SLYTITGAQLAFGHVALLDHADFSLEAGERVGLIGRNGAGKSSLLKIVAELARPDDGLITRQQDLVTVYVPQEPEFDGDV
TVFDTVAAGLTRASALLDEYNTVAHELAETPEGAQHDALLARMNALQSSLDATDAWNWRTRVATTLAQIGLDGDAQVGSL
SGGMQKRVALARALVVQPDVLLLDEPTNHLDFDGIRWLEELLVSQRAGLLFITHDRAFLDRVATRIVELDRGRLLSYPGN
FSAYQTRKAQQLEVERVENEKFDKLLAQEEVWIRKGVEARRTRSVGRIARLVQMRKEREERRNVQGNVKLDVGQGEKSGK
IVAELTDVTKRYGERTVVDRFSTTVMRGDKIGFVGPNGAGKTTLLKLILGELQPDDGAVRVGTNLQVAYFDQMRAQLDLE
KSLADTISPGSDWVEINGQKKHVMSYLGDFLFAPERARSPVKSLSGGERNRLLLARLFARPANVLVLDEPTNDLDIPTLE
LLEELLTDYDGTVLLVSHDRAFLDNVVTSVIASEDAGKWREYVGGFTDWQIQRERSEQIAQKDAPKEPPKEAAPKESAAG
RNAQRTVKLSFKEQRELEALPERIAALEAEQKAIGAQIEEGSIFVKDAQEGARLTERYAAIDDELLVAIERWDELESKKK

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=536, Percent_Identity=32.6492537313433, Blast_Score=223, Evalue=4e-58,
Organism=Homo sapiens, GI10947137, Length=533, Percent_Identity=31.1444652908068, Blast_Score=201, Evalue=2e-51,
Organism=Homo sapiens, GI27881506, Length=533, Percent_Identity=31.1444652908068, Blast_Score=201, Evalue=2e-51,
Organism=Homo sapiens, GI10947135, Length=507, Percent_Identity=30.5719921104536, Blast_Score=186, Evalue=8e-47,
Organism=Homo sapiens, GI69354671, Length=507, Percent_Identity=30.5719921104536, Blast_Score=186, Evalue=8e-47,
Organism=Escherichia coli, GI1787182, Length=643, Percent_Identity=47.5894245723173, Blast_Score=547, Evalue=1e-157,
Organism=Escherichia coli, GI2367384, Length=521, Percent_Identity=36.468330134357, Blast_Score=338, Evalue=5e-94,
Organism=Escherichia coli, GI1789751, Length=620, Percent_Identity=31.1290322580645, Blast_Score=260, Evalue=2e-70,
Organism=Escherichia coli, GI1787041, Length=510, Percent_Identity=31.5686274509804, Blast_Score=253, Evalue=3e-68,
Organism=Escherichia coli, GI87081782, Length=511, Percent_Identity=24.853228962818, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI1788165, Length=188, Percent_Identity=33.5106382978723, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI145693107, Length=532, Percent_Identity=23.8721804511278, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1789891, Length=252, Percent_Identity=29.3650793650794, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1788761, Length=243, Percent_Identity=29.6296296296296, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788225, Length=245, Percent_Identity=28.1632653061224, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1786398, Length=338, Percent_Identity=28.1065088757396, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI1786253, Length=197, Percent_Identity=34.010152284264, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1789672, Length=251, Percent_Identity=25.0996015936255, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI87081709, Length=233, Percent_Identity=28.755364806867, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1787029, Length=241, Percent_Identity=27.8008298755187, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1789864, Length=241, Percent_Identity=27.3858921161826, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1787089, Length=248, Percent_Identity=30.241935483871, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786872, Length=239, Percent_Identity=28.0334728033473, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1788644, Length=209, Percent_Identity=27.2727272727273, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1787712, Length=200, Percent_Identity=29.5, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1790544, Length=269, Percent_Identity=27.8810408921933, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1787164, Length=184, Percent_Identity=31.5217391304348, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1787758, Length=176, Percent_Identity=27.8409090909091, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1790467, Length=235, Percent_Identity=28.0851063829787, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI87081791, Length=197, Percent_Identity=27.4111675126904, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17559834, Length=545, Percent_Identity=30.4587155963303, Blast_Score=226, Evalue=3e-59,
Organism=Caenorhabditis elegans, GI17553372, Length=531, Percent_Identity=33.7099811676083, Blast_Score=211, Evalue=7e-55,
Organism=Caenorhabditis elegans, GI17555318, Length=515, Percent_Identity=29.3203883495146, Blast_Score=191, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI17511077, Length=253, Percent_Identity=28.0632411067194, Blast_Score=68, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320874, Length=539, Percent_Identity=30.2411873840445, Blast_Score=211, Evalue=2e-55,
Organism=Saccharomyces cerevisiae, GI6321121, Length=541, Percent_Identity=30.1293900184843, Blast_Score=192, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6325030, Length=397, Percent_Identity=30.7304785894207, Blast_Score=155, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6323278, Length=419, Percent_Identity=26.9689737470167, Blast_Score=122, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6324314, Length=423, Percent_Identity=26.9503546099291, Blast_Score=122, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6323959, Length=290, Percent_Identity=27.2413793103448, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24666836, Length=518, Percent_Identity=33.5907335907336, Blast_Score=226, Evalue=5e-59,
Organism=Drosophila melanogaster, GI24642252, Length=546, Percent_Identity=30.7692307692308, Blast_Score=216, Evalue=4e-56,
Organism=Drosophila melanogaster, GI18859989, Length=546, Percent_Identity=30.7692307692308, Blast_Score=216, Evalue=4e-56,
Organism=Drosophila melanogaster, GI24641342, Length=533, Percent_Identity=29.4559099437148, Blast_Score=208, Evalue=1e-53,
Organism=Drosophila melanogaster, GI221500365, Length=182, Percent_Identity=30.7692307692308, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI116007184, Length=182, Percent_Identity=30.7692307692308, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 71124; Mature: 70993

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLYTITGAQLAFGHVALLDHADFSLEAGERVGLIGRNGAGKSSLLKIVAELARPDDGLI
CEEEEECCCHHHHHHEEEEECCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCE
TRQQDLVTVYVPQEPEFDGDVTVFDTVAAGLTRASALLDEYNTVAHELAETPEGAQHDAL
EECCCEEEEECCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
LARMNALQSSLDATDAWNWRTRVATTLAQIGLDGDAQVGSLSGGMQKRVALARALVVQPD
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
VLLLDEPTNHLDFDGIRWLEELLVSQRAGLLFITHDRAFLDRVATRIVELDRGRLLSYPG
EEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHCCCCEECCCC
NFSAYQTRKAQQLEVERVENEKFDKLLAQEEVWIRKGVEARRTRSVGRIARLVQMRKERE
CCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
ERRNVQGNVKLDVGQGEKSGKIVAELTDVTKRYGERTVVDRFSTTVMRGDKIGFVGPNGA
HHCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEECCCCC
GKTTLLKLILGELQPDDGAVRVGTNLQVAYFDQMRAQLDLEKSLADTISPGSDWVEINGQ
CHHHHHHHHHHHCCCCCCCEEECCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCEEEECCC
KKHVMSYLGDFLFAPERARSPVKSLSGGERNRLLLARLFARPANVLVLDEPTNDLDIPTL
HHHHHHHHHHHHCCCHHHCCHHHHCCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCHH
ELLEELLTDYDGTVLLVSHDRAFLDNVVTSVIASEDAGKWREYVGGFTDWQIQRERSEQI
HHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHH
AQKDAPKEPPKEAAPKESAAGRNAQRTVKLSFKEQRELEALPERIAALEAEQKAIGAQIE
HHHCCCCCCCHHCCCCHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCEEC
EGSIFVKDAQEGARLTERYAAIDDELLVAIERWDELESKKK
CCCEEEECCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SLYTITGAQLAFGHVALLDHADFSLEAGERVGLIGRNGAGKSSLLKIVAELARPDDGLI
EEEEECCCHHHHHHEEEEECCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCE
TRQQDLVTVYVPQEPEFDGDVTVFDTVAAGLTRASALLDEYNTVAHELAETPEGAQHDAL
EECCCEEEEECCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
LARMNALQSSLDATDAWNWRTRVATTLAQIGLDGDAQVGSLSGGMQKRVALARALVVQPD
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
VLLLDEPTNHLDFDGIRWLEELLVSQRAGLLFITHDRAFLDRVATRIVELDRGRLLSYPG
EEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHCCCCEECCCC
NFSAYQTRKAQQLEVERVENEKFDKLLAQEEVWIRKGVEARRTRSVGRIARLVQMRKERE
CCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
ERRNVQGNVKLDVGQGEKSGKIVAELTDVTKRYGERTVVDRFSTTVMRGDKIGFVGPNGA
HHCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEECCCCC
GKTTLLKLILGELQPDDGAVRVGTNLQVAYFDQMRAQLDLEKSLADTISPGSDWVEINGQ
CHHHHHHHHHHHCCCCCCCEEECCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCEEEECCC
KKHVMSYLGDFLFAPERARSPVKSLSGGERNRLLLARLFARPANVLVLDEPTNDLDIPTL
HHHHHHHHHHHHCCCHHHCCHHHHCCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCHH
ELLEELLTDYDGTVLLVSHDRAFLDNVVTSVIASEDAGKWREYVGGFTDWQIQRERSEQI
HHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHH
AQKDAPKEPPKEAAPKESAAGRNAQRTVKLSFKEQRELEALPERIAALEAEQKAIGAQIE
HHHCCCCCCCHHCCCCHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCEEC
EGSIFVKDAQEGARLTERYAAIDDELLVAIERWDELESKKK
CCCEEEECCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Endonuclease; Excision [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]