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The map label for this gene is hicA2 [H]

Identifier: 186476611

GI number: 186476611

Start: 2120849

End: 2121064

Strand: Direct

Name: hicA2 [H]

Synonym: Bphy_1856

Alternate gene names: 186476611

Gene position: 2120849-2121064 (Clockwise)

Preceding gene: 186476610

Following gene: 186476612

Centisome position: 60.96

GC content: 51.39

Gene sequence:

>216_bases
ATGTTTAATATAAACACATGTCAACAACACGGAGGGACGGTGAAACAGAGTGAGTTCAAGAGGTGGTTAGCTGATCAGGG
CGCGAGATTCAAGGAAGGATCGAATCACACGAAGGTCTACCTGAACGGCAAACAAACCACCCTGCCGAGGCACCCCGGCC
ACGAAATCGGGGAAGGTCTGAGGCAGAAGATTCTGAAGCAGCTCGGTCTGAAGTGA

Upstream 100 bases:

>100_bases
CAAGAACCCCACATATAGCAGGGCTGCACCGCTCGGGTTTGGACGGGCAGCAAAAGAATAAGCAAAAATGCTTGTACAGT
CCTTGCTTGTTTAAACATTA

Downstream 100 bases:

>100_bases
AGGGAGCCCCGAACGGGGCTTTCTCCGCACCGTCTCTCAAGCAATGGAGTGCACTATGTTGCGTTACCCCGCCCTGTTCG
AACCGGATGGCGACGGATTC

Product: YcfA family protein

Products: NA

Alternate protein names: Endoribonuclease HicA 2; Toxin HicA 2 [H]

Number of amino acids: Translated: 71; Mature: 71

Protein sequence:

>71_residues
MFNINTCQQHGGTVKQSEFKRWLADQGARFKEGSNHTKVYLNGKQTTLPRHPGHEIGEGLRQKILKQLGLK

Sequences:

>Translated_71_residues
MFNINTCQQHGGTVKQSEFKRWLADQGARFKEGSNHTKVYLNGKQTTLPRHPGHEIGEGLRQKILKQLGLK
>Mature_71_residues
MFNINTCQQHGGTVKQSEFKRWLADQGARFKEGSNHTKVYLNGKQTTLPRHPGHEIGEGLRQKILKQLGLK

Specific function: Part of a toxin-antitoxin (TA) module. A probable translation-independent mRNA interferase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HicA mRNA interferase family [H]

Homologues:

Organism=Escherichia coli, GI87081911, Length=57, Percent_Identity=56.140350877193, Blast_Score=71, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015146
- InterPro:   IPR012933 [H]

Pfam domain/function: PF07927 YcfA [H]

EC number: NA

Molecular weight: Translated: 8086; Mature: 8086

Theoretical pI: Translated: 10.82; Mature: 10.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNINTCQQHGGTVKQSEFKRWLADQGARFKEGSNHTKVYLNGKQTTLPRHPGHEIGEGL
CCCCCCHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHH
RQKILKQLGLK
HHHHHHHHCCC
>Mature Secondary Structure
MFNINTCQQHGGTVKQSEFKRWLADQGARFKEGSNHTKVYLNGKQTTLPRHPGHEIGEGL
CCCCCCHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHH
RQKILKQLGLK
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]