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The map label for this gene is hicB2 [H]

Identifier: 186476612

GI number: 186476612

Start: 2121120

End: 2121536

Strand: Direct

Name: hicB2 [H]

Synonym: Bphy_1857

Alternate gene names: 186476612

Gene position: 2121120-2121536 (Clockwise)

Preceding gene: 186476611

Following gene: 186476620

Centisome position: 60.97

GC content: 60.67

Gene sequence:

>417_bases
ATGTTGCGTTACCCCGCCCTGTTCGAACCGGATGGCGACGGATTCGCCGTGTCATTTCGGGACATCCCCGAAGCGCTGAC
CAGTGGCGAGACGATGGAAGAAGCTCGAGCGATGGCGGCAGACGCGCTGCTGACGGCGATGGACTTCTATTTCGAAGATC
GCCGCCCGGTGCCCGAGCCGTCGAAGGCCAAAAAGGGCGAGGAACTCGTCGCCCTGCCCGCCAGCGTATCGGCCAAGGTA
TTACTGCTGAACGAGATGATCCGCCAGCAGGTGACGCCATCCGAGCTCGCGCGTCGCCTCGGAACTAGTCCACAGGTCGT
GAATCGGATCGTCGACGTCAAGCACGCGACGAAGATTGATACTATTGCCGAGGCCCTCGAGGCCCTAGGCAAACATCTCG
AAATTGGAGTCGCTTGA

Upstream 100 bases:

>100_bases
GAAGGTCTGAGGCAGAAGATTCTGAAGCAGCTCGGTCTGAAGTGAAGGGAGCCCCGAACGGGGCTTTCTCCGCACCGTCT
CTCAAGCAATGGAGTGCACT

Downstream 100 bases:

>100_bases
CGCGCTGCCTGGTGGCACGCCAAGGAGATTGGATGAAACTGTCTCAATACATCGCCCAGCTGCAGTCAATTTTGGAAACC
GAGGGTGACCTGCAAGTTGT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 138; Mature: 138

Protein sequence:

>138_residues
MLRYPALFEPDGDGFAVSFRDIPEALTSGETMEEARAMAADALLTAMDFYFEDRRPVPEPSKAKKGEELVALPASVSAKV
LLLNEMIRQQVTPSELARRLGTSPQVVNRIVDVKHATKIDTIAEALEALGKHLEIGVA

Sequences:

>Translated_138_residues
MLRYPALFEPDGDGFAVSFRDIPEALTSGETMEEARAMAADALLTAMDFYFEDRRPVPEPSKAKKGEELVALPASVSAKV
LLLNEMIRQQVTPSELARRLGTSPQVVNRIVDVKHATKIDTIAEALEALGKHLEIGVA
>Mature_138_residues
MLRYPALFEPDGDGFAVSFRDIPEALTSGETMEEARAMAADALLTAMDFYFEDRRPVPEPSKAKKGEELVALPASVSAKV
LLLNEMIRQQVTPSELARRLGTSPQVVNRIVDVKHATKIDTIAEALEALGKHLEIGVA

Specific function: Part of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin preventing effects of the HicA 2 toxin [H]

COG id: COG1598

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH cro/C1-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693129, Length=135, Percent_Identity=48.8888888888889, Blast_Score=130, Evalue=3e-32,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005357 [H]

Pfam domain/function: PF03681 UPF0150 [H]

EC number: NA

Molecular weight: Translated: 15062; Mature: 15062

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRYPALFEPDGDGFAVSFRDIPEALTSGETMEEARAMAADALLTAMDFYFEDRRPVPEP
CCCCCCCCCCCCCCEEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
SKAKKGEELVALPASVSAKVLLLNEMIRQQVTPSELARRLGTSPQVVNRIVDVKHATKID
CCCCCCCCEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHH
TIAEALEALGKHLEIGVA
HHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLRYPALFEPDGDGFAVSFRDIPEALTSGETMEEARAMAADALLTAMDFYFEDRRPVPEP
CCCCCCCCCCCCCCEEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
SKAKKGEELVALPASVSAKVLLLNEMIRQQVTPSELARRLGTSPQVVNRIVDVKHATKID
CCCCCCCCEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHH
TIAEALEALGKHLEIGVA
HHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]