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The map label for this gene is hutI

Identifier: 186476568

GI number: 186476568

Start: 2069364

End: 2070584

Strand: Reverse

Name: hutI

Synonym: Bphy_1810

Alternate gene names: 186476568

Gene position: 2070584-2069364 (Counterclockwise)

Preceding gene: 186476569

Following gene: 186476567

Centisome position: 59.51

GC content: 66.34

Gene sequence:

>1221_bases
ATGAAGCAAACCGTCTGGAACCATCTGAAGCTCTGCCCTCAGGGCGATCCCGCTCAAACGATCGACGACGCCGCGATCGC
TGTCGAGAACGGCCGCATCGTGTGGCTCGGCGCGGTGCGCGAACTGCCAGCGCAGTATGCCGCGTGGCCGCGCGAAGACC
TTGGCGGCGCGTGGGTGACGCCGGGTCTCGTCGATTGCCATACGCATCTGGTGTATGGCGGCCAGCGCGCCGACGAATTT
GCACAGCGTCTCGCGGGCGTCAGCTACGAAGAGATTGCGAAGCAGGGCGGCGGCATCGTATCGACGGTACGCGCGACGCG
TGCCGCCGACGAGGCGTCGCTCTTCGCGCAATCGGCGGCGCGCCTTGAAGCGATGCTCGCCGAAGGCGTTACTGCCATCG
AAATCAAATCCGGCTATGGGCTCGATCTGCAAAGCGAGCGCAAGATGCTGCGCGTCGCGCGGCAACTCGGCGAACGTTAC
CCTGTGAAGGTCTATACGACGTTTCTCGGCGCGCATGCGTTGCCGCCCGAATTCGCGAGCCGCGCCGACGATTACATCGA
CGAAGTCTGCGAGGGCATGCTGCCCGCGCTCGCGGATGAAGGACTCGTCGATGCCGTCGACGTGTTCTGCGAACGCATCG
GCTTTTCGCTCGAACAGAGCGAGCGCGTGTTCAATGCGGCCGCGCGCCACGGGCTGCCCGTCAAGATGCATGCGGAGCAG
TTGTCGAATGCCGGCGGCACGGCGCTCGCCGCGCGCTACGGCGCCTTGTCGGCGGACCATCTGGAGTTTCTCGACGAAGC
GGGCGTCGCCGCGATGAAGGAGGCGGGCACGGTCGCCGTGCTGCTGCCGGGCGCTTACTACTTCATCCGCGAAACGCAGT
TGCCGCCCGTCGAACTGTTGCGCCGCTACGGCGTGCCCATCGCGATTTCGACGGACAGCAATCCGGGCACTTCGCCCGCC
ACGTCGTTGCCGCTCATGATGAACATGGCGACGACGCTGTTCCGGATGACGGTGCCCGAGGTGCTGCGAGGCGTGACGTG
CCACGCGGCGCAGGCGCTCGGCAAAGCCGATACGCATGGCACGCTCGCCGTGGGCCGGGCCGCCGACTTCGCAGTATGGT
CGGTGCAATCGCTCGCGGAACTTGCGTACTGGATCGGACGGCCGCTGTGCGAGCGCGTCGTGCGCGGCGGCGAAACCGTC
CATCTGCGTCACGCCCGATGA

Upstream 100 bases:

>100_bases
TGCTTGCCGTCAGCATCCGCTACACGAAACCACCGCGAGCCTGACCGCTCGCGCACCAGGCTCGCACACCAGGCCTGCAC
ACCACACGGACAGCCCGGCC

Downstream 100 bases:

>100_bases
GCCAGACCCGAACGGAATCGAACATGACTGAAGCCACTCAATCGCTATTTGCCGATCACGCGTATCTGCCCGAAGGCTGG
CGGCGCAATGTGCTGCTGCA

Product: imidazolonepropionase

Products: NA

Alternate protein names: Imidazolone-5-propionate hydrolase

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MKQTVWNHLKLCPQGDPAQTIDDAAIAVENGRIVWLGAVRELPAQYAAWPREDLGGAWVTPGLVDCHTHLVYGGQRADEF
AQRLAGVSYEEIAKQGGGIVSTVRATRAADEASLFAQSAARLEAMLAEGVTAIEIKSGYGLDLQSERKMLRVARQLGERY
PVKVYTTFLGAHALPPEFASRADDYIDEVCEGMLPALADEGLVDAVDVFCERIGFSLEQSERVFNAAARHGLPVKMHAEQ
LSNAGGTALAARYGALSADHLEFLDEAGVAAMKEAGTVAVLLPGAYYFIRETQLPPVELLRRYGVPIAISTDSNPGTSPA
TSLPLMMNMATTLFRMTVPEVLRGVTCHAAQALGKADTHGTLAVGRAADFAVWSVQSLAELAYWIGRPLCERVVRGGETV
HLRHAR

Sequences:

>Translated_406_residues
MKQTVWNHLKLCPQGDPAQTIDDAAIAVENGRIVWLGAVRELPAQYAAWPREDLGGAWVTPGLVDCHTHLVYGGQRADEF
AQRLAGVSYEEIAKQGGGIVSTVRATRAADEASLFAQSAARLEAMLAEGVTAIEIKSGYGLDLQSERKMLRVARQLGERY
PVKVYTTFLGAHALPPEFASRADDYIDEVCEGMLPALADEGLVDAVDVFCERIGFSLEQSERVFNAAARHGLPVKMHAEQ
LSNAGGTALAARYGALSADHLEFLDEAGVAAMKEAGTVAVLLPGAYYFIRETQLPPVELLRRYGVPIAISTDSNPGTSPA
TSLPLMMNMATTLFRMTVPEVLRGVTCHAAQALGKADTHGTLAVGRAADFAVWSVQSLAELAYWIGRPLCERVVRGGETV
HLRHAR
>Mature_406_residues
MKQTVWNHLKLCPQGDPAQTIDDAAIAVENGRIVWLGAVRELPAQYAAWPREDLGGAWVTPGLVDCHTHLVYGGQRADEF
AQRLAGVSYEEIAKQGGGIVSTVRATRAADEASLFAQSAARLEAMLAEGVTAIEIKSGYGLDLQSERKMLRVARQLGERY
PVKVYTTFLGAHALPPEFASRADDYIDEVCEGMLPALADEGLVDAVDVFCERIGFSLEQSERVFNAAARHGLPVKMHAEQ
LSNAGGTALAARYGALSADHLEFLDEAGVAAMKEAGTVAVLLPGAYYFIRETQLPPVELLRRYGVPIAISTDSNPGTSPA
TSLPLMMNMATTLFRMTVPEVLRGVTCHAAQALGKADTHGTLAVGRAADFAVWSVQSLAELAYWIGRPLCERVVRGGETV
HLRHAR

Specific function: Unknown

COG id: COG1228

COG function: function code Q; Imidazolonepropionase and related amidohydrolases

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hutI family

Homologues:

Organism=Homo sapiens, GI223972677, Length=393, Percent_Identity=35.8778625954198, Blast_Score=223, Evalue=3e-58,
Organism=Caenorhabditis elegans, GI17555004, Length=371, Percent_Identity=35.3099730458221, Blast_Score=228, Evalue=3e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HUTI_BURP8 (B2JCJ1)

Other databases:

- EMBL:   CP001043
- RefSeq:   YP_001858038.1
- ProteinModelPortal:   B2JCJ1
- GeneID:   6243301
- GenomeReviews:   CP001043_GR
- KEGG:   bph:Bphy_1810
- HOGENOM:   HBG686142
- OMA:   MNMACTL
- ProtClustDB:   PRK09356
- GO:   GO:0005737
- HAMAP:   MF_00372
- InterPro:   IPR006680
- InterPro:   IPR005920
- InterPro:   IPR011059
- TIGRFAMs:   TIGR01224

Pfam domain/function: PF01979 Amidohydro_1; SSF51338 Metalo_hydrolase

EC number: =3.5.2.7

Molecular weight: Translated: 43750; Mature: 43750

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: NA

Important sites: BINDING 76-76 BINDING 89-89 BINDING 139-139 BINDING 172-172 BINDING 240-240

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQTVWNHLKLCPQGDPAQTIDDAAIAVENGRIVWLGAVRELPAQYAAWPREDLGGAWVT
CCCCHHHHHHCCCCCCCCCCCCCCCEEEECCCEEEEECHHHCCHHHHCCCCHHCCCCCCC
PGLVDCHTHLVYGGQRADEFAQRLAGVSYEEIAKQGGGIVSTVRATRAADEASLFAQSAA
CCHHHHHHHHEECCCHHHHHHHHHHCCCHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHH
RLEAMLAEGVTAIEIKSGYGLDLQSERKMLRVARQLGERYPVKVYTTFLGAHALPPEFAS
HHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCEEEHHHHHCCCCCHHHHH
RADDYIDEVCEGMLPALADEGLVDAVDVFCERIGFSLEQSERVFNAAARHGLPVKMHAEQ
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEHHH
LSNAGGTALAARYGALSADHLEFLDEAGVAAMKEAGTVAVLLPGAYYFIRETQLPPVELL
HCCCCCHHHHHHHCCCCHHHHHHHHHCCHHHHHCCCCEEEEECCCEEEEECCCCCHHHHH
RRYGVPIAISTDSNPGTSPATSLPLMMNMATTLFRMTVPEVLRGVTCHAAQALGKADTHG
HHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCC
TLAVGRAADFAVWSVQSLAELAYWIGRPLCERVVRGGETVHLRHAR
CEEECCCCHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCEEEEECCC
>Mature Secondary Structure
MKQTVWNHLKLCPQGDPAQTIDDAAIAVENGRIVWLGAVRELPAQYAAWPREDLGGAWVT
CCCCHHHHHHCCCCCCCCCCCCCCCEEEECCCEEEEECHHHCCHHHHCCCCHHCCCCCCC
PGLVDCHTHLVYGGQRADEFAQRLAGVSYEEIAKQGGGIVSTVRATRAADEASLFAQSAA
CCHHHHHHHHEECCCHHHHHHHHHHCCCHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHH
RLEAMLAEGVTAIEIKSGYGLDLQSERKMLRVARQLGERYPVKVYTTFLGAHALPPEFAS
HHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCEEEHHHHHCCCCCHHHHH
RADDYIDEVCEGMLPALADEGLVDAVDVFCERIGFSLEQSERVFNAAARHGLPVKMHAEQ
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEHHH
LSNAGGTALAARYGALSADHLEFLDEAGVAAMKEAGTVAVLLPGAYYFIRETQLPPVELL
HCCCCCHHHHHHHCCCCHHHHHHHHHCCHHHHHCCCCEEEEECCCEEEEECCCCCHHHHH
RRYGVPIAISTDSNPGTSPATSLPLMMNMATTLFRMTVPEVLRGVTCHAAQALGKADTHG
HHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCC
TLAVGRAADFAVWSVQSLAELAYWIGRPLCERVVRGGETVHLRHAR
CEEECCCCHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA