Click here to switch to the map view.

The map label for this gene is mtaD [H]

Identifier: 186476567

GI number: 186476567

Start: 2067937

End: 2069367

Strand: Reverse

Name: mtaD [H]

Synonym: Bphy_1809

Alternate gene names: 186476567

Gene position: 2069367-2067937 (Counterclockwise)

Preceding gene: 186476568

Following gene: 186476566

Centisome position: 59.48

GC content: 65.62

Gene sequence:

>1431_bases
ATGAGCCAGACCCGAACGGAATCGAACATGACTGAAGCCACTCAATCGCTATTTGCCGATCACGCGTATCTGCCCGAAGG
CTGGCGGCGCAATGTGCTGCTGCAATGGGACGCGCAGGGCGCGCTCGTCGCCGTCACGCCCGACGCGCCAGCGCCCGCAG
GCGTCGCTAAGGCGCACGGCCCGGTGTTGCCCGGCATGCCAAATCTGCATTCGCATGCATTCCAGCGCGCGATGGCGGGC
CTCACCGAATATCGCGCCGCATTGGGCAAGGGCGTCGTCGACAGCTTCTGGTCGTGGCGCGACCTGATGTACCGCTTTGC
CGCACGCATCACGCCGGAAGGACTCGCGTCGATCGCGCAATGGCTGTACATCGAGATGCTGAAGGCGGGGTACACGTCCG
TCTGCGAGTTCCATTATGTGCATCACATGCAGGACGGCGGGCGCTATGCGAACGAGGCCGAACTCGCGCAGCGCGTGGTC
GATGCTGCAAGCGAGAGCGGCATCGGCATCACGATGCTGCCCGTGCTGTATCAGTACGCAGGATTCGGCGCGCAGCCGCC
GCGCGACGATCAGCGCCGCTTCATCAACACGCCCGATAGTCTGCTCGCGTTGCTCGACACGCTGCGTCGCGCTCGCCCCG
AACATGGCGCGTTGCGCTATGGCGTCGCGCCGCATTCGTTGCGCGCGGTATCGAACGATTCGCTGCGCGCGCTGCTGAAT
GGGCTCGATGCGATGTCGCCAGGTGCACCCGTGCACATTCATATCGCCGAACAGACGGCGGAAGTGGACGCGTGCGTCGA
AACGGAAGGCGCGCGGCCGGTGCAATGGCTGCTCGATCGCTTCGACGTCGACGCGCACTGGTGCCTCGTGCACGCGACGC
ATGTCGATGCCGATGAAACTGCCAGGCTCGCGAAAAGCGGCGCGATCGCGGGGTTGTGCCTGACGACGGAAGCGAATCTC
GGCGACGGCATTTTCCCCGCGCATGATTATCTTGCGCTGAAGGGGCGCATCGGCGTCGGCAGCGACAGCCATATCGGCGT
CGACTGGCGCGCGGAACTGCGGCTGCTCGAATACGGTCAACGTCTGTCGAGGCGCCAGCGCAACGTGCTCGCGTCAGCGG
ACATGCCGCGCGTGGCGGACCGCCTCTATGCAGGGTCGCTGGAAGGCGGCGCGCTCGCGACGGGCCGCGCCGTCGGTGCA
TTGAAGGCGGGCGCGCGCGCCGATTTCATGGTGCTCGATGCGAACCATCCGAACCTCGCGGAACAGCCGGGCGACGCGTG
GCTATCGGGTGTCGTATTCTGCGAGCATGGCGAAACGCCTGTGCGCGACGTGTACGCGGGCGGCGCGAAAGTCGTCGACA
ATCGTCGACATCGCGACGAAGACGAGGCGTACGCGAACTATCGCGCGGCCCTCGCCGAACTGCTGAAGTGA

Upstream 100 bases:

>100_bases
GGTCGGTGCAATCGCTCGCGGAACTTGCGTACTGGATCGGACGGCCGCTGTGCGAGCGCGTCGTGCGCGGCGGCGAAACC
GTCCATCTGCGTCACGCCCG

Downstream 100 bases:

>100_bases
AGCGCAAGTCTCGCGCTGCCGCATGACGACTCAACCTTGGGAAGCACCGACGACATGACTGCTACCGACACCTTGCCCGT
CTTCTCGCTACATCGGGGAA

Product: N-formimino-L-glutamate deiminase

Products: NA

Alternate protein names: MTA/SAH deaminase [H]

Number of amino acids: Translated: 476; Mature: 475

Protein sequence:

>476_residues
MSQTRTESNMTEATQSLFADHAYLPEGWRRNVLLQWDAQGALVAVTPDAPAPAGVAKAHGPVLPGMPNLHSHAFQRAMAG
LTEYRAALGKGVVDSFWSWRDLMYRFAARITPEGLASIAQWLYIEMLKAGYTSVCEFHYVHHMQDGGRYANEAELAQRVV
DAASESGIGITMLPVLYQYAGFGAQPPRDDQRRFINTPDSLLALLDTLRRARPEHGALRYGVAPHSLRAVSNDSLRALLN
GLDAMSPGAPVHIHIAEQTAEVDACVETEGARPVQWLLDRFDVDAHWCLVHATHVDADETARLAKSGAIAGLCLTTEANL
GDGIFPAHDYLALKGRIGVGSDSHIGVDWRAELRLLEYGQRLSRRQRNVLASADMPRVADRLYAGSLEGGALATGRAVGA
LKAGARADFMVLDANHPNLAEQPGDAWLSGVVFCEHGETPVRDVYAGGAKVVDNRRHRDEDEAYANYRAALAELLK

Sequences:

>Translated_476_residues
MSQTRTESNMTEATQSLFADHAYLPEGWRRNVLLQWDAQGALVAVTPDAPAPAGVAKAHGPVLPGMPNLHSHAFQRAMAG
LTEYRAALGKGVVDSFWSWRDLMYRFAARITPEGLASIAQWLYIEMLKAGYTSVCEFHYVHHMQDGGRYANEAELAQRVV
DAASESGIGITMLPVLYQYAGFGAQPPRDDQRRFINTPDSLLALLDTLRRARPEHGALRYGVAPHSLRAVSNDSLRALLN
GLDAMSPGAPVHIHIAEQTAEVDACVETEGARPVQWLLDRFDVDAHWCLVHATHVDADETARLAKSGAIAGLCLTTEANL
GDGIFPAHDYLALKGRIGVGSDSHIGVDWRAELRLLEYGQRLSRRQRNVLASADMPRVADRLYAGSLEGGALATGRAVGA
LKAGARADFMVLDANHPNLAEQPGDAWLSGVVFCEHGETPVRDVYAGGAKVVDNRRHRDEDEAYANYRAALAELLK
>Mature_475_residues
SQTRTESNMTEATQSLFADHAYLPEGWRRNVLLQWDAQGALVAVTPDAPAPAGVAKAHGPVLPGMPNLHSHAFQRAMAGL
TEYRAALGKGVVDSFWSWRDLMYRFAARITPEGLASIAQWLYIEMLKAGYTSVCEFHYVHHMQDGGRYANEAELAQRVVD
AASESGIGITMLPVLYQYAGFGAQPPRDDQRRFINTPDSLLALLDTLRRARPEHGALRYGVAPHSLRAVSNDSLRALLNG
LDAMSPGAPVHIHIAEQTAEVDACVETEGARPVQWLLDRFDVDAHWCLVHATHVDADETARLAKSGAIAGLCLTTEANLG
DGIFPAHDYLALKGRIGVGSDSHIGVDWRAELRLLEYGQRLSRRQRNVLASADMPRVADRLYAGSLEGGALATGRAVGAL
KAGARADFMVLDANHPNLAEQPGDAWLSGVVFCEHGETPVRDVYAGGAKVVDNRRHRDEDEAYANYRAALAELLK

Specific function: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine [H]

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MTA/SAH deaminase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17540282, Length=438, Percent_Identity=28.9954337899543, Blast_Score=191, Evalue=1e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.4.28 [H]

Molecular weight: Translated: 51853; Mature: 51722

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQTRTESNMTEATQSLFADHAYLPEGWRRNVLLQWDAQGALVAVTPDAPAPAGVAKAHG
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCHHCCC
PVLPGMPNLHSHAFQRAMAGLTEYRAALGKGVVDSFWSWRDLMYRFAARITPEGLASIAQ
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
WLYIEMLKAGYTSVCEFHYVHHMQDGGRYANEAELAQRVVDAASESGIGITMLPVLYQYA
HHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCEEHHHHHHHHH
GFGAQPPRDDQRRFINTPDSLLALLDTLRRARPEHGALRYGVAPHSLRAVSNDSLRALLN
CCCCCCCCCCHHHHCCCHHHHHHHHHHHHHCCCCCCCEEECCCCHHHHHCCCHHHHHHHH
GLDAMSPGAPVHIHIAEQTAEVDACVETEGARPVQWLLDRFDVDAHWCLVHATHVDADET
HHHCCCCCCCEEEEEECCCHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEEEEEECCHHHH
ARLAKSGAIAGLCLTTEANLGDGIFPAHDYLALKGRIGVGSDSHIGVDWRAELRLLEYGQ
HHHHHCCCEEEEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHH
RLSRRQRNVLASADMPRVADRLYAGSLEGGALATGRAVGALKAGARADFMVLDANHPNLA
HHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCEECCHHHHHHHCCCCCCEEEEECCCCCCC
EQPGDAWLSGVVFCEHGETPVRDVYAGGAKVVDNRRHRDEDEAYANYRAALAELLK
CCCCHHHHCCEEEEECCCCCHHHHHCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
SQTRTESNMTEATQSLFADHAYLPEGWRRNVLLQWDAQGALVAVTPDAPAPAGVAKAHG
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCHHCCC
PVLPGMPNLHSHAFQRAMAGLTEYRAALGKGVVDSFWSWRDLMYRFAARITPEGLASIAQ
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
WLYIEMLKAGYTSVCEFHYVHHMQDGGRYANEAELAQRVVDAASESGIGITMLPVLYQYA
HHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCEEHHHHHHHHH
GFGAQPPRDDQRRFINTPDSLLALLDTLRRARPEHGALRYGVAPHSLRAVSNDSLRALLN
CCCCCCCCCCHHHHCCCHHHHHHHHHHHHHCCCCCCCEEECCCCHHHHHCCCHHHHHHHH
GLDAMSPGAPVHIHIAEQTAEVDACVETEGARPVQWLLDRFDVDAHWCLVHATHVDADET
HHHCCCCCCCEEEEEECCCHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEEEEEECCHHHH
ARLAKSGAIAGLCLTTEANLGDGIFPAHDYLALKGRIGVGSDSHIGVDWRAELRLLEYGQ
HHHHHCCCEEEEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHH
RLSRRQRNVLASADMPRVADRLYAGSLEGGALATGRAVGALKAGARADFMVLDANHPNLA
HHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCEECCHHHHHHHCCCCCCEEEEECCCCCCC
EQPGDAWLSGVVFCEHGETPVRDVYAGGAKVVDNRRHRDEDEAYANYRAALAELLK
CCCCHHHHCCEEEEECCCCCHHHHHCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA