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The map label for this gene is rnr [H]

Identifier: 186476455

GI number: 186476455

Start: 1931729

End: 1934182

Strand: Reverse

Name: rnr [H]

Synonym: Bphy_1697

Alternate gene names: 186476455

Gene position: 1934182-1931729 (Counterclockwise)

Preceding gene: 186476463

Following gene: 186476454

Centisome position: 55.59

GC content: 64.96

Gene sequence:

>2454_bases
TTGAGCAAATATCCGTATCCGATTCCAAGCCGCGAAGAAATCCTCGGCGTGCTGCGCACGAGTGAAACGCCGCTTGCAGC
GAACGACATCGCCGAAGCACTGTCGATCAAGCGCCAGGAGCGCGAAGGGTTTTTCAAGCGCCTCGCCGCGATGGAGCGCG
ATGGCCAGATCAGACTCGATCAGCGCGGGCATTACCAACTGACTCATCCGTCGAACTTCGTCGCGGGCCGCGTGCAGGGC
CATCGCGACGGCTACGGCTTTCTGATCCGCGACGACGGCCAGGACGACCTGTTCCTGCCGACGGGCGAAATGCAGAAGGT
CATGCACAACGACCGCGTGCTCGCGCGCATCGTCGGCTATGACCGGCGCGGCCGGCCCGAAGGCCATATCGTCGAGGTCA
CCGACCGCGCTAACAAGCGCGTGATCGGGCGTCTGTTGAATGAGAACGGCGCGCTGATCGTCGTGCCCGAAGAGAAGCGC
ATCGGCCACGACATCCTGATCACGCAGAACACGAAGAAGGCGAAGGTGGGGCAGGTGGTCGTCGTCGAACTGACGGACTT
TCCGAGCCGCCATTCGCAGCCGCTCGGACGCGTCATCGAAGTACTGGGCGACATCGACGACCCCGGCATGGAGATCGAAA
TCGCGGTGCGCAAGTACGGCGTGCCGCACGAGTTCAGCCAGGCCGCGCTCGACGCCGCCGCGAAGCTGCCCGACGAAGTG
CGGCCCGTCGACATCAAGCATCGCGTCGATCTGCGCGACGTGCCGCTCGTCACGATCGACGGCGAGGACGCACGCGATTT
CGACGATGCGGTGTACTGCGAGCCCATCAAGGTCGGGCGTGGCGACGGCTTCCGCCTGATTGTCGCAATCGCCGACGTGT
CACATTACGTGCTGCCCGACGGCGGCCTGGATGTCGACGCGATCGAGCGCAGCACGTCGGTATACTTCCCGCGCCGCGTG
ATTCCGATGCTGCCGGAAAAGCTGTCGAACGGTCTTTGCTCGCTGAACCCGCAAGTGGATCGCTGCGTGCTGGTCTGCGA
CATGGTCATCACCGCGCGCGGTGAGATCAAGGCGTATCAGTTCTATCCGGGCGTGATGCACTCGGCCGCGCGTCTCACGT
ACACGGAAGTCGCGGCCGTGCTGACCAACACGAAGGGGCCGGAAGCGACGCGCCGCGCGGCGTTGCTGCCGCAACTGCAA
AATCTGTACGGCGTCTATAAGTCGTTGTTTGCCGCCCGTCAGAAGCGTGGCGCGATCGACTTCGATACGACGGAGACGTA
CATCGTCTGCAACGCGCAGGGCAAGATCGAGCAGATCGTGCCGCGTCACCGCAACGACGCGCACAAGCTGATCGAGGAAT
GCATGCTGGCCGCGAACGTCTGCGCGGCCGACTTCATGAAGCGCAACAAGCATCCGGGTCTGTACCGCGTGCACGCCGGA
CCGACGGCCGAGCGCCTCGAGAATCTGCGCACGTTCCTGCGTGGAATGGGCCTCACGCTTGGCGGCGGCGACACGCCGCA
TGCCAGCGATTACGCCGCGCTGATGGCGCACATCCGCGACCGTCCCGACGCGCAGATGCTCCAGACGATGTTGCTGCGCT
CGATGCAGCAGGCCGTCTACAGTCCGGAGAACATTGGTCACTTCGGTCTCGCGTATGAGGCGTACGCGCACTTCACGAGC
CCGATCCGCCGCTATCCCGACCTGCTCACGCACCGCGCGATCTACGCGATTTTGCAAGGCCGCAAGTACGAGCCGAAGGC
GCCGCATGGCGTCGAGCTGAACACGGCGCTGTCGCCGCGCGCGCGCGCGCTGCAGGCGGAAGACGAGAAGCGGGGCAACC
GCGGCCGTCCAAACACGGCCATCTGGGAAGAACTCGGCTTGCACTGCTCGGCGAACGAGCGCCGTGCGGATGAGGCATCG
CGCGACGTCGAAGCCTGGCTCAAGTGCTACTTCATGCGCGACAAGCTCGGTGAAGAGTACGGCGGCATGGTGAGCGGCGT
GACGTCGTTCGGCATCTTCGTGCAGCTCGACGCGCTTTTTATCGAAGGGCTCGTGCACGTGACGGAACTCGGCTCCGACT
ACTTCCAGTACGACGAGATCAAGAACGAACTGCGCGGCGAGCGCACGGGCATCCGTTACCGGTTGTCGGACCGCGTGCGC
GTGCAGGTGAGCCGCGTCGATCTCGATGCGCGCAAGATCGACTTCCGCCTGGTGCGCGACACGCCCGTGAAGTCGCAGGC
GCATCGGGCGACCACTGCGGACAAAGCGAGCGATCTCGGCGGCCCGCGTGTGCGTTCGATCGAGCGTGCCGCGCAGGCCG
AAGGCGGCCGTCGCAAGAAAGCGCCTGCACAGACCGCGGCCGTGAAGGAAGCGCGCGCGGCGCGCAAGGCGGCGGTGTCG
AAGAAGCGCGCGGCGTCGAAATCGTCGGCAAAGCCGGCGCGCAAGAAGCGTTGA

Upstream 100 bases:

>100_bases
AGCAGTTGCAGTCACGAGCGCAGTTGCAGTTCAAGTTCAGATAGAGCCGCGTCAACCACCCGCCGACGTCCACGCAACGA
GAACAATCATCGACAAGCCC

Downstream 100 bases:

>100_bases
TCACGCAGTCGATGCCGCAGTGGATTCTGTTGTCACGCCGCGCGCACGTGCGCGGTGCTCATTCTCATCGGGCGCGCCGC
GATCGGACCAGTCGATACGA

Product: ribonuclease R

Products: NA

Alternate protein names: RNase R; VacB protein homolog [H]

Number of amino acids: Translated: 817; Mature: 816

Protein sequence:

>817_residues
MSKYPYPIPSREEILGVLRTSETPLAANDIAEALSIKRQEREGFFKRLAAMERDGQIRLDQRGHYQLTHPSNFVAGRVQG
HRDGYGFLIRDDGQDDLFLPTGEMQKVMHNDRVLARIVGYDRRGRPEGHIVEVTDRANKRVIGRLLNENGALIVVPEEKR
IGHDILITQNTKKAKVGQVVVVELTDFPSRHSQPLGRVIEVLGDIDDPGMEIEIAVRKYGVPHEFSQAALDAAAKLPDEV
RPVDIKHRVDLRDVPLVTIDGEDARDFDDAVYCEPIKVGRGDGFRLIVAIADVSHYVLPDGGLDVDAIERSTSVYFPRRV
IPMLPEKLSNGLCSLNPQVDRCVLVCDMVITARGEIKAYQFYPGVMHSAARLTYTEVAAVLTNTKGPEATRRAALLPQLQ
NLYGVYKSLFAARQKRGAIDFDTTETYIVCNAQGKIEQIVPRHRNDAHKLIEECMLAANVCAADFMKRNKHPGLYRVHAG
PTAERLENLRTFLRGMGLTLGGGDTPHASDYAALMAHIRDRPDAQMLQTMLLRSMQQAVYSPENIGHFGLAYEAYAHFTS
PIRRYPDLLTHRAIYAILQGRKYEPKAPHGVELNTALSPRARALQAEDEKRGNRGRPNTAIWEELGLHCSANERRADEAS
RDVEAWLKCYFMRDKLGEEYGGMVSGVTSFGIFVQLDALFIEGLVHVTELGSDYFQYDEIKNELRGERTGIRYRLSDRVR
VQVSRVDLDARKIDFRLVRDTPVKSQAHRATTADKASDLGGPRVRSIERAAQAEGGRRKKAPAQTAAVKEARAARKAAVS
KKRAASKSSAKPARKKR

Sequences:

>Translated_817_residues
MSKYPYPIPSREEILGVLRTSETPLAANDIAEALSIKRQEREGFFKRLAAMERDGQIRLDQRGHYQLTHPSNFVAGRVQG
HRDGYGFLIRDDGQDDLFLPTGEMQKVMHNDRVLARIVGYDRRGRPEGHIVEVTDRANKRVIGRLLNENGALIVVPEEKR
IGHDILITQNTKKAKVGQVVVVELTDFPSRHSQPLGRVIEVLGDIDDPGMEIEIAVRKYGVPHEFSQAALDAAAKLPDEV
RPVDIKHRVDLRDVPLVTIDGEDARDFDDAVYCEPIKVGRGDGFRLIVAIADVSHYVLPDGGLDVDAIERSTSVYFPRRV
IPMLPEKLSNGLCSLNPQVDRCVLVCDMVITARGEIKAYQFYPGVMHSAARLTYTEVAAVLTNTKGPEATRRAALLPQLQ
NLYGVYKSLFAARQKRGAIDFDTTETYIVCNAQGKIEQIVPRHRNDAHKLIEECMLAANVCAADFMKRNKHPGLYRVHAG
PTAERLENLRTFLRGMGLTLGGGDTPHASDYAALMAHIRDRPDAQMLQTMLLRSMQQAVYSPENIGHFGLAYEAYAHFTS
PIRRYPDLLTHRAIYAILQGRKYEPKAPHGVELNTALSPRARALQAEDEKRGNRGRPNTAIWEELGLHCSANERRADEAS
RDVEAWLKCYFMRDKLGEEYGGMVSGVTSFGIFVQLDALFIEGLVHVTELGSDYFQYDEIKNELRGERTGIRYRLSDRVR
VQVSRVDLDARKIDFRLVRDTPVKSQAHRATTADKASDLGGPRVRSIERAAQAEGGRRKKAPAQTAAVKEARAARKAAVS
KKRAASKSSAKPARKKR
>Mature_816_residues
SKYPYPIPSREEILGVLRTSETPLAANDIAEALSIKRQEREGFFKRLAAMERDGQIRLDQRGHYQLTHPSNFVAGRVQGH
RDGYGFLIRDDGQDDLFLPTGEMQKVMHNDRVLARIVGYDRRGRPEGHIVEVTDRANKRVIGRLLNENGALIVVPEEKRI
GHDILITQNTKKAKVGQVVVVELTDFPSRHSQPLGRVIEVLGDIDDPGMEIEIAVRKYGVPHEFSQAALDAAAKLPDEVR
PVDIKHRVDLRDVPLVTIDGEDARDFDDAVYCEPIKVGRGDGFRLIVAIADVSHYVLPDGGLDVDAIERSTSVYFPRRVI
PMLPEKLSNGLCSLNPQVDRCVLVCDMVITARGEIKAYQFYPGVMHSAARLTYTEVAAVLTNTKGPEATRRAALLPQLQN
LYGVYKSLFAARQKRGAIDFDTTETYIVCNAQGKIEQIVPRHRNDAHKLIEECMLAANVCAADFMKRNKHPGLYRVHAGP
TAERLENLRTFLRGMGLTLGGGDTPHASDYAALMAHIRDRPDAQMLQTMLLRSMQQAVYSPENIGHFGLAYEAYAHFTSP
IRRYPDLLTHRAIYAILQGRKYEPKAPHGVELNTALSPRARALQAEDEKRGNRGRPNTAIWEELGLHCSANERRADEASR
DVEAWLKCYFMRDKLGEEYGGMVSGVTSFGIFVQLDALFIEGLVHVTELGSDYFQYDEIKNELRGERTGIRYRLSDRVRV
QVSRVDLDARKIDFRLVRDTPVKSQAHRATTADKASDLGGPRVRSIERAAQAEGGRRKKAPAQTAAVKEARAARKAAVSK
KRAASKSSAKPARKKR

Specific function: 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs [H]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI190014623, Length=471, Percent_Identity=29.2993630573248, Blast_Score=182, Evalue=8e-46,
Organism=Homo sapiens, GI190014625, Length=471, Percent_Identity=29.2993630573248, Blast_Score=182, Evalue=8e-46,
Organism=Homo sapiens, GI134288890, Length=443, Percent_Identity=30.2483069977427, Blast_Score=167, Evalue=5e-41,
Organism=Homo sapiens, GI19115966, Length=469, Percent_Identity=29.637526652452, Blast_Score=149, Evalue=1e-35,
Organism=Homo sapiens, GI219521928, Length=469, Percent_Identity=29.637526652452, Blast_Score=148, Evalue=2e-35,
Organism=Homo sapiens, GI156105693, Length=297, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=8e-11,
Organism=Homo sapiens, GI156105695, Length=297, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=9e-11,
Organism=Escherichia coli, GI87082383, Length=742, Percent_Identity=49.4609164420485, Blast_Score=686, Evalue=0.0,
Organism=Escherichia coli, GI1787542, Length=678, Percent_Identity=26.6961651917404, Blast_Score=195, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI212645896, Length=416, Percent_Identity=30.0480769230769, Blast_Score=173, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI17553506, Length=445, Percent_Identity=28.5393258426966, Blast_Score=143, Evalue=4e-34,
Organism=Saccharomyces cerevisiae, GI6324552, Length=654, Percent_Identity=25.5351681957187, Blast_Score=133, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24649634, Length=495, Percent_Identity=28.8888888888889, Blast_Score=180, Evalue=4e-45,
Organism=Drosophila melanogaster, GI24654592, Length=418, Percent_Identity=29.1866028708134, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI19922976, Length=418, Percent_Identity=29.1866028708134, Blast_Score=147, Evalue=3e-35,
Organism=Drosophila melanogaster, GI24654597, Length=418, Percent_Identity=29.1866028708134, Blast_Score=147, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013223
- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR004476
- InterPro:   IPR011805
- InterPro:   IPR013668 [H]

Pfam domain/function: PF08461 HTH_12; PF08206 OB_RNB; PF00773 RNB; PF00575 S1 [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 91383; Mature: 91251

Theoretical pI: Translated: 9.39; Mature: 9.39

Prosite motif: PS50126 S1 ; PS01175 RIBONUCLEASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKYPYPIPSREEILGVLRTSETPLAANDIAEALSIKRQEREGFFKRLAAMERDGQIRLD
CCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEC
QRGHYQLTHPSNFVAGRVQGHRDGYGFLIRDDGQDDLFLPTGEMQKVMHNDRVLARIVGY
CCCCEEEECCCCCEEECCCCCCCCEEEEEEECCCCCEEECCHHHHHHHHCCHHHHHHHCC
DRRGRPEGHIVEVTDRANKRVIGRLLNENGALIVVPEEKRIGHDILITQNTKKAKVGQVV
CCCCCCCCCEEEECCCCCHHHHHHHHCCCCCEEEEECCCCCCCEEEEECCCCCCCCCCEE
VVELTDFPSRHSQPLGRVIEVLGDIDDPGMEIEIAVRKYGVPHEFSQAALDAAAKLPDEV
EEEECCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCC
RPVDIKHRVDLRDVPLVTIDGEDARDFDDAVYCEPIKVGRGDGFRLIVAIADVSHYVLPD
CCCCEEECCCCCCCCEEEECCCCCCCCCCCEEECEEEECCCCCCEEEEEEECCCCEECCC
GGLDVDAIERSTSVYFPRRVIPMLPEKLSNGLCSLNPQVDRCVLVCDMVITARGEIKAYQ
CCCCHHHHHCCCCCCCCHHHHHHCHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEE
FYPGVMHSAARLTYTEVAAVLTNTKGPEATRRAALLPQLQNLYGVYKSLFAARQKRGAID
ECCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
FDTTETYIVCNAQGKIEQIVPRHRNDAHKLIEECMLAANVCAADFMKRNKHPGLYRVHAG
CCCCCEEEEECCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECC
PTAERLENLRTFLRGMGLTLGGGDTPHASDYAALMAHIRDRPDAQMLQTMLLRSMQQAVY
CHHHHHHHHHHHHHHCCEEECCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHC
SPENIGHFGLAYEAYAHFTSPIRRYPDLLTHRAIYAILQGRKYEPKAPHGVELNTALSPR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCH
ARALQAEDEKRGNRGRPNTAIWEELGLHCSANERRADEASRDVEAWLKCYFMRDKLGEEY
HHHHCCHHHHCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHH
GGMVSGVTSFGIFVQLDALFIEGLVHVTELGSDYFQYDEIKNELRGERTGIRYRLSDRVR
CCHHHHHHHHHHHEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEECCCEE
VQVSRVDLDARKIDFRLVRDTPVKSQAHRATTADKASDLGGPRVRSIERAAQAEGGRRKK
EEEEEECCCCCEEEEEEEECCCCCHHHHHHCCHHHHHCCCCHHHHHHHHHHHHCCCCCCC
APAQTAAVKEARAARKAAVSKKRAASKSSAKPARKKR
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCC
>Mature Secondary Structure 
SKYPYPIPSREEILGVLRTSETPLAANDIAEALSIKRQEREGFFKRLAAMERDGQIRLD
CCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEC
QRGHYQLTHPSNFVAGRVQGHRDGYGFLIRDDGQDDLFLPTGEMQKVMHNDRVLARIVGY
CCCCEEEECCCCCEEECCCCCCCCEEEEEEECCCCCEEECCHHHHHHHHCCHHHHHHHCC
DRRGRPEGHIVEVTDRANKRVIGRLLNENGALIVVPEEKRIGHDILITQNTKKAKVGQVV
CCCCCCCCCEEEECCCCCHHHHHHHHCCCCCEEEEECCCCCCCEEEEECCCCCCCCCCEE
VVELTDFPSRHSQPLGRVIEVLGDIDDPGMEIEIAVRKYGVPHEFSQAALDAAAKLPDEV
EEEECCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCC
RPVDIKHRVDLRDVPLVTIDGEDARDFDDAVYCEPIKVGRGDGFRLIVAIADVSHYVLPD
CCCCEEECCCCCCCCEEEECCCCCCCCCCCEEECEEEECCCCCCEEEEEEECCCCEECCC
GGLDVDAIERSTSVYFPRRVIPMLPEKLSNGLCSLNPQVDRCVLVCDMVITARGEIKAYQ
CCCCHHHHHCCCCCCCCHHHHHHCHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEE
FYPGVMHSAARLTYTEVAAVLTNTKGPEATRRAALLPQLQNLYGVYKSLFAARQKRGAID
ECCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
FDTTETYIVCNAQGKIEQIVPRHRNDAHKLIEECMLAANVCAADFMKRNKHPGLYRVHAG
CCCCCEEEEECCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECC
PTAERLENLRTFLRGMGLTLGGGDTPHASDYAALMAHIRDRPDAQMLQTMLLRSMQQAVY
CHHHHHHHHHHHHHHCCEEECCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHC
SPENIGHFGLAYEAYAHFTSPIRRYPDLLTHRAIYAILQGRKYEPKAPHGVELNTALSPR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCH
ARALQAEDEKRGNRGRPNTAIWEELGLHCSANERRADEASRDVEAWLKCYFMRDKLGEEY
HHHHCCHHHHCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHH
GGMVSGVTSFGIFVQLDALFIEGLVHVTELGSDYFQYDEIKNELRGERTGIRYRLSDRVR
CCHHHHHHHHHHHEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEECCCEE
VQVSRVDLDARKIDFRLVRDTPVKSQAHRATTADKASDLGGPRVRSIERAAQAEGGRRKK
EEEEEECCCCCEEEEEEEECCCCCHHHHHHCCHHHHHCCCCHHHHHHHHHHHHCCCCCCC
APAQTAAVKEARAARKAAVSKKRAASKSSAKPARKKR
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]