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The map label for this gene is epsA [H]

Identifier: 186476448

GI number: 186476448

Start: 1923974

End: 1925260

Strand: Reverse

Name: epsA [H]

Synonym: Bphy_1690

Alternate gene names: 186476448

Gene position: 1925260-1923974 (Counterclockwise)

Preceding gene: 186476449

Following gene: 186476447

Centisome position: 55.34

GC content: 65.73

Gene sequence:

>1287_bases
ATGCAACTCAATCGAGTTTGCGAGCAGTGGAGGACTCAGGCGCGCGCTGCGCGCCTGTCTTCGTGGTGGCGAACGGTTCG
CTCACGGGCGAGGCTCGACCTTGCACGCGTGAACTGTCTGGCCGCGTCCCGATGGGCAGCGCCCGCAGCCGCCGCTGTGC
TGCTGTCGGGCTGCGCGCTGTCGCCGGGGATGACTTTCCGGGGCATGCCTTCGGGCGATGCGGCGCAAGCGGTGAGTGCC
GCGCACGGCGCGGCGGCTGGTACAGGTTCGCAACAGGCGTCGGGCAGCGATCGCGCACCCACGGGTTCGCTGGTCGAAAT
TACCGATGACCTCGTCGCAAAGCAGCAGCAGGAACGGCCGACGGGCGTGCCGGACGACGTGCGCAGCCTGTTCGCCAAGC
CGGAGCCCTATGTGATCGGGCCGGGTGACGTCCTCAGCATCGTCGTGTGGGACCACCCGGAACTCAGCATGCCGGCCGCC
ACGACGGGAGGCGGACAGAGCACGTCCGGGGCGCCGCTCGTCGCGCCCGGCTATACGGTCGATGTGAATGGTTTTATCCA
GTACGCCTATATCGGACCCATCAAGGTCGAGGGCCTCTCGGAAATGGGCGTGCGGGATCTGCTCACGAGCAAGCTGGGCC
GCTATGTGAGACAGCCGCAGATGACGGTGCGCGTCGAGACTTACCGCAGCAAGCGCGTTTATCTCGACGGCGAAGTGAAA
TCGCCGGGCGTGCAGGTGCTCAACGACGTGGTGATGACGCTTCCCGAAGCGATCAACCGGGCAGGCGGCTTTACCGACAA
GTCGGACCGGTCGAAGGTGACGCTGACGCGCGGGGACAGGACGGTGGTGGTGGATATGCCGGACATGATCCGCAACAACG
TGAACCCGGACCGGATCATCGTGCGCGACGGCGACCTGATACGCGTCTATGGGCAAAACGACAGCAAGGTCTTTGTGATT
GGCGAAGTGCAGCGTCCCGGCGGGCTACCGTTCAACAACGGGCGCATGACGCTGAACCAGGCGCTGGGCGACGCGGGCGG
CATCAGCCAGACTTCCGGCGACGCGTCGCAGGTCTACGTCGTGCGGGGACGCGATGTGGGCAGGCGCGTGGTCTATCACC
TCGACGCGACCTCGGCTTCCGCGATGGCCACGGCCGATTCGTTCGAACTCAAGCCGAACGATGTGGTGTTCGTCGATGCG
TCGTCACTGGTGAAATGGAGCCGCGTCATCGGACTGATCCTGCCTGCGACCCAGGCGGCGTCGGCGACGCGAGCACTCGG
CTACTGA

Upstream 100 bases:

>100_bases
CGAGCGGGCATCACCAGGCATCGTGAAATGAGCAGCATCGGACCTGATTCGCCGCGCACCGTACGCCGCGGACTGGCCGC
ACGCAATATGGGGGTTTGAC

Downstream 100 bases:

>100_bases
TCGTTATATATCGATGCACGTGCCCGGCACCTCGTGGCGGGCACCGACGGAGAGACAGATTGAAACAGCGCGAATATCTG
CTAGAGGGGTCGCTTGACGA

Product: polysaccharide export protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MQLNRVCEQWRTQARAARLSSWWRTVRSRARLDLARVNCLAASRWAAPAAAAVLLSGCALSPGMTFRGMPSGDAAQAVSA
AHGAAAGTGSQQASGSDRAPTGSLVEITDDLVAKQQQERPTGVPDDVRSLFAKPEPYVIGPGDVLSIVVWDHPELSMPAA
TTGGGQSTSGAPLVAPGYTVDVNGFIQYAYIGPIKVEGLSEMGVRDLLTSKLGRYVRQPQMTVRVETYRSKRVYLDGEVK
SPGVQVLNDVVMTLPEAINRAGGFTDKSDRSKVTLTRGDRTVVVDMPDMIRNNVNPDRIIVRDGDLIRVYGQNDSKVFVI
GEVQRPGGLPFNNGRMTLNQALGDAGGISQTSGDASQVYVVRGRDVGRRVVYHLDATSASAMATADSFELKPNDVVFVDA
SSLVKWSRVIGLILPATQAASATRALGY

Sequences:

>Translated_428_residues
MQLNRVCEQWRTQARAARLSSWWRTVRSRARLDLARVNCLAASRWAAPAAAAVLLSGCALSPGMTFRGMPSGDAAQAVSA
AHGAAAGTGSQQASGSDRAPTGSLVEITDDLVAKQQQERPTGVPDDVRSLFAKPEPYVIGPGDVLSIVVWDHPELSMPAA
TTGGGQSTSGAPLVAPGYTVDVNGFIQYAYIGPIKVEGLSEMGVRDLLTSKLGRYVRQPQMTVRVETYRSKRVYLDGEVK
SPGVQVLNDVVMTLPEAINRAGGFTDKSDRSKVTLTRGDRTVVVDMPDMIRNNVNPDRIIVRDGDLIRVYGQNDSKVFVI
GEVQRPGGLPFNNGRMTLNQALGDAGGISQTSGDASQVYVVRGRDVGRRVVYHLDATSASAMATADSFELKPNDVVFVDA
SSLVKWSRVIGLILPATQAASATRALGY
>Mature_428_residues
MQLNRVCEQWRTQARAARLSSWWRTVRSRARLDLARVNCLAASRWAAPAAAAVLLSGCALSPGMTFRGMPSGDAAQAVSA
AHGAAAGTGSQQASGSDRAPTGSLVEITDDLVAKQQQERPTGVPDDVRSLFAKPEPYVIGPGDVLSIVVWDHPELSMPAA
TTGGGQSTSGAPLVAPGYTVDVNGFIQYAYIGPIKVEGLSEMGVRDLLTSKLGRYVRQPQMTVRVETYRSKRVYLDGEVK
SPGVQVLNDVVMTLPEAINRAGGFTDKSDRSKVTLTRGDRTVVVDMPDMIRNNVNPDRIIVRDGDLIRVYGQNDSKVFVI
GEVQRPGGLPFNNGRMTLNQALGDAGGISQTSGDASQVYVVRGRDVGRRVVYHLDATSASAMATADSFELKPNDVVFVDA
SSLVKWSRVIGLILPATQAASATRALGY

Specific function: Probably involved in polymerization and/or export of exopolysaccharide EPS I which functions as a virulence factor [H]

COG id: COG1596

COG function: function code M; Periplasmic protein involved in polysaccharide export

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BexD/CtrA/VexA family [H]

Homologues:

Organism=Escherichia coli, GI1788376, Length=287, Percent_Identity=36.5853658536585, Blast_Score=186, Evalue=3e-48,
Organism=Escherichia coli, GI1787218, Length=284, Percent_Identity=38.0281690140845, Blast_Score=179, Evalue=4e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003715
- InterPro:   IPR019554 [H]

Pfam domain/function: PF02563 Poly_export; PF10531 SLBB [H]

EC number: NA

Molecular weight: Translated: 45716; Mature: 45716

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLNRVCEQWRTQARAARLSSWWRTVRSRARLDLARVNCLAASRWAAPAAAAVLLSGCAL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCC
SPGMTFRGMPSGDAAQAVSAAHGAAAGTGSQQASGSDRAPTGSLVEITDDLVAKQQQERP
CCCCEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHCCC
TGVPDDVRSLFAKPEPYVIGPGDVLSIVVWDHPELSMPAATTGGGQSTSGAPLVAPGYTV
CCCCHHHHHHHCCCCCEEECCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCEEECCCEEE
DVNGFIQYAYIGPIKVEGLSEMGVRDLLTSKLGRYVRQPQMTVRVETYRSKRVYLDGEVK
ECCCEEEEEEECCEEECCCHHCCHHHHHHHHHHHHHCCCCEEEEEEEECCCEEEECCCCC
SPGVQVLNDVVMTLPEAINRAGGFTDKSDRSKVTLTRGDRTVVVDMPDMIRNNVNPDRII
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCEEEEEECHHHHHCCCCCCEEE
VRDGDLIRVYGQNDSKVFVIGEVQRPGGLPFNNGRMTLNQALGDAGGISQTSGDASQVYV
EECCCEEEEEECCCCEEEEEEEECCCCCCCCCCCCEEHHHHCCCCCCCCCCCCCCEEEEE
VRGRDVGRRVVYHLDATSASAMATADSFELKPNDVVFVDASSLVKWSRVIGLILPATQAA
EECCCCCCEEEEEECCCCCCCEEECCCCCCCCCCEEEEEHHHHHHHHHHHHHEECCCHHH
SATRALGY
HHHHHCCC
>Mature Secondary Structure
MQLNRVCEQWRTQARAARLSSWWRTVRSRARLDLARVNCLAASRWAAPAAAAVLLSGCAL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCC
SPGMTFRGMPSGDAAQAVSAAHGAAAGTGSQQASGSDRAPTGSLVEITDDLVAKQQQERP
CCCCEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHCCC
TGVPDDVRSLFAKPEPYVIGPGDVLSIVVWDHPELSMPAATTGGGQSTSGAPLVAPGYTV
CCCCHHHHHHHCCCCCEEECCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCEEECCCEEE
DVNGFIQYAYIGPIKVEGLSEMGVRDLLTSKLGRYVRQPQMTVRVETYRSKRVYLDGEVK
ECCCEEEEEEECCEEECCCHHCCHHHHHHHHHHHHHCCCCEEEEEEEECCCEEEECCCCC
SPGVQVLNDVVMTLPEAINRAGGFTDKSDRSKVTLTRGDRTVVVDMPDMIRNNVNPDRII
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCEEEEEECHHHHHCCCCCCEEE
VRDGDLIRVYGQNDSKVFVIGEVQRPGGLPFNNGRMTLNQALGDAGGISQTSGDASQVYV
EECCCEEEEEECCCCEEEEEEEECCCCCCCCCCCCEEHHHHCCCCCCCCCCCCCCEEEEE
VRGRDVGRRVVYHLDATSASAMATADSFELKPNDVVFVDASSLVKWSRVIGLILPATQAA
EECCCCCCEEEEEECCCCCCCEEECCCCCCCCCCEEEEEHHHHHHHHHHHHHEECCCHHH
SATRALGY
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]