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The map label for this gene is tas [H]

Identifier: 186476396

GI number: 186476396

Start: 1859480

End: 1860532

Strand: Reverse

Name: tas [H]

Synonym: Bphy_1638

Alternate gene names: 186476396

Gene position: 1860532-1859480 (Counterclockwise)

Preceding gene: 186476399

Following gene: 186476395

Centisome position: 53.48

GC content: 62.77

Gene sequence:

>1053_bases
ATGGAATACCGCAAGCTCGGCGAAACGGATGTACAGGTCAGCCTGATCGGTCTCGGCACGATGACGTGGGGCGAGCAGAA
TACGGAGCGCGATGCCCACGAGCAGATGGATTACGCACTCGCTCAGGGCATCACGCTAATCGATGCCGCCGAGATGTATC
CCGTGCCGCCGCGCCCGGAAACGCAAGGATCGACGGAACGCTATATCGGCACGTGGCTCGCGCAGCATCGTTCGATGCGC
GACAAGATCGTGCTCGCCACCAAGATCGCCGGCCCCGCGCGTCAGCCGCACAACCCGCGCCACATTCGCGGCGAGGGCAA
CCAGTTCGACCGCAAGAATCTCACCGAGGCGCTGAACGACAGCCTGAAGCGTCTGCAAACCGATTACGTCGACCTGTATC
AGTTGCACTGGCCCGATCGCAGCACGATGACGTTCGGCCGTCCCGCGTATCCGTGGATCGACGACGCGTACACGGTGCCC
ATCGAAGAGACGCTTTCCGTGCTCGCCGATTTCGTGAAAGAAGGGAAGGTGCGTCATATCGGTGTGTCGAACGAAACGCC
GTGGGGCGTTGCACAATTCCTGCGCGCGTCGGAGAAGCTTGGCTTGCCGCGCATCGTATCGATCCAGAATCCCTATAGCC
TCTTGAACCGGACGTTCGAAGCGGGGCTTTCGGAGTTCACGCATCGCGAGCATGTCGGTCTGCTGGCGTATTCGCCGCTC
GCGTTCGGCTGGCTCTCGGGCAAGTACGAGCGCGGGGCGCGCCCGGCAGGCGCGCGCATCACGCTGTTCGAGCGCTTCCA
GCGCTACAGCAAACCGCAGGCCGTGCATGCGACGAGCCGCTATGTCGAACTCGCCAGGCGCCACGGTCTGTCGCCCGCGC
AATTCGCGCTCGCGTTCGTGAACAGCCGGCCCTTCGTCACGAGCAATCTGATCGGCGCAACGTCGCTCGATCAGTTGAAA
GAGAACATTGCGAGCGTCGACGTGAAGCTCTCGGCGGACGCATTGGCCGAGATCGATGCGCTGCACGAATTGCAACCGAA
CCCGGCGCCCTGA

Upstream 100 bases:

>100_bases
TTCAGACGACATTCTATCCACGCACGCGTTTGACGCGGACATGGTAATTTCGCCGTTTACCGATGGATCACCCGTCAGAA
CACGAAACAGGAACGAATCG

Downstream 100 bases:

>100_bases
GCGCGGGATTCGACACGCTGCCAGACACGGCGTGCCGCGACGGCGGTACGCCGACACCCACAGAACGCTTGCGCCAGATG
CGTGAGCCCAACACCGCACC

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MEYRKLGETDVQVSLIGLGTMTWGEQNTERDAHEQMDYALAQGITLIDAAEMYPVPPRPETQGSTERYIGTWLAQHRSMR
DKIVLATKIAGPARQPHNPRHIRGEGNQFDRKNLTEALNDSLKRLQTDYVDLYQLHWPDRSTMTFGRPAYPWIDDAYTVP
IEETLSVLADFVKEGKVRHIGVSNETPWGVAQFLRASEKLGLPRIVSIQNPYSLLNRTFEAGLSEFTHREHVGLLAYSPL
AFGWLSGKYERGARPAGARITLFERFQRYSKPQAVHATSRYVELARRHGLSPAQFALAFVNSRPFVTSNLIGATSLDQLK
ENIASVDVKLSADALAEIDALHELQPNPAP

Sequences:

>Translated_350_residues
MEYRKLGETDVQVSLIGLGTMTWGEQNTERDAHEQMDYALAQGITLIDAAEMYPVPPRPETQGSTERYIGTWLAQHRSMR
DKIVLATKIAGPARQPHNPRHIRGEGNQFDRKNLTEALNDSLKRLQTDYVDLYQLHWPDRSTMTFGRPAYPWIDDAYTVP
IEETLSVLADFVKEGKVRHIGVSNETPWGVAQFLRASEKLGLPRIVSIQNPYSLLNRTFEAGLSEFTHREHVGLLAYSPL
AFGWLSGKYERGARPAGARITLFERFQRYSKPQAVHATSRYVELARRHGLSPAQFALAFVNSRPFVTSNLIGATSLDQLK
ENIASVDVKLSADALAEIDALHELQPNPAP
>Mature_350_residues
MEYRKLGETDVQVSLIGLGTMTWGEQNTERDAHEQMDYALAQGITLIDAAEMYPVPPRPETQGSTERYIGTWLAQHRSMR
DKIVLATKIAGPARQPHNPRHIRGEGNQFDRKNLTEALNDSLKRLQTDYVDLYQLHWPDRSTMTFGRPAYPWIDDAYTVP
IEETLSVLADFVKEGKVRHIGVSNETPWGVAQFLRASEKLGLPRIVSIQNPYSLLNRTFEAGLSEFTHREHVGLLAYSPL
AFGWLSGKYERGARPAGARITLFERFQRYSKPQAVHATSRYVELARRHGLSPAQFALAFVNSRPFVTSNLIGATSLDQLK
ENIASVDVKLSADALAEIDALHELQPNPAP

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=360, Percent_Identity=30.2777777777778, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI4504825, Length=358, Percent_Identity=30.1675977653631, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI27436964, Length=360, Percent_Identity=28.3333333333333, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI27436962, Length=360, Percent_Identity=28.3333333333333, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI27436966, Length=360, Percent_Identity=28.0555555555556, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI27436971, Length=362, Percent_Identity=28.4530386740331, Blast_Score=111, Evalue=8e-25,
Organism=Homo sapiens, GI41152114, Length=249, Percent_Identity=30.1204819277108, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI223718702, Length=323, Percent_Identity=28.1733746130031, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI41327764, Length=337, Percent_Identity=27.299703264095, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1789199, Length=350, Percent_Identity=59.1428571428571, Blast_Score=426, Evalue=1e-120,
Organism=Escherichia coli, GI87081735, Length=356, Percent_Identity=30.0561797752809, Blast_Score=137, Evalue=9e-34,
Organism=Escherichia coli, GI1789375, Length=348, Percent_Identity=30.7471264367816, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI1788070, Length=346, Percent_Identity=29.7687861271676, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1788081, Length=345, Percent_Identity=27.536231884058, Blast_Score=88, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI6323998, Length=324, Percent_Identity=26.5432098765432, Blast_Score=98, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6319958, Length=324, Percent_Identity=25.9259259259259, Blast_Score=95, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6325169, Length=356, Percent_Identity=24.7191011235955, Blast_Score=94, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6319951, Length=317, Percent_Identity=25.2365930599369, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6322615, Length=269, Percent_Identity=24.907063197026, Blast_Score=84, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6320079, Length=236, Percent_Identity=28.8135593220339, Blast_Score=67, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6320576, Length=311, Percent_Identity=24.7588424437299, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6324694, Length=191, Percent_Identity=31.9371727748691, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24646159, Length=334, Percent_Identity=26.0479041916168, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24646155, Length=340, Percent_Identity=27.9411764705882, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 39363; Mature: 39363

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYRKLGETDVQVSLIGLGTMTWGEQNTERDAHEQMDYALAQGITLIDAAEMYPVPPRPE
CCCCCCCCCCEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEHHHHCCCCCCCC
TQGSTERYIGTWLAQHRSMRDKIVLATKIAGPARQPHNPRHIRGEGNQFDRKNLTEALND
CCCCHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCEECCCCCCCCHHHHHHHHHH
SLKRLQTDYVDLYQLHWPDRSTMTFGRPAYPWIDDAYTVPIEETLSVLADFVKEGKVRHI
HHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHCCCEEEE
GVSNETPWGVAQFLRASEKLGLPRIVSIQNPYSLLNRTFEAGLSEFTHREHVGLLAYSPL
ECCCCCCHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCH
AFGWLSGKYERGARPAGARITLFERFQRYSKPQAVHATSRYVELARRHGLSPAQFALAFV
HHHHHCCCHHCCCCCCCCEEHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHH
NSRPFVTSNLIGATSLDQLKENIASVDVKLSADALAEIDALHELQPNPAP
CCCCCEECCCCCCCHHHHHHHHHHHCCEEECHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MEYRKLGETDVQVSLIGLGTMTWGEQNTERDAHEQMDYALAQGITLIDAAEMYPVPPRPE
CCCCCCCCCCEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEHHHHCCCCCCCC
TQGSTERYIGTWLAQHRSMRDKIVLATKIAGPARQPHNPRHIRGEGNQFDRKNLTEALND
CCCCHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCEECCCCCCCCHHHHHHHHHH
SLKRLQTDYVDLYQLHWPDRSTMTFGRPAYPWIDDAYTVPIEETLSVLADFVKEGKVRHI
HHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHCCCEEEE
GVSNETPWGVAQFLRASEKLGLPRIVSIQNPYSLLNRTFEAGLSEFTHREHVGLLAYSPL
ECCCCCCHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCH
AFGWLSGKYERGARPAGARITLFERFQRYSKPQAVHATSRYVELARRHGLSPAQFALAFV
HHHHHCCCHHCCCCCCCCEEHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHH
NSRPFVTSNLIGATSLDQLKENIASVDVKLSADALAEIDALHELQPNPAP
CCCCCEECCCCCCCHHHHHHHHHHHCCEEECHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9560382; 9278503 [H]