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The map label for this gene is xylH [H]

Identifier: 186476356

GI number: 186476356

Start: 1814207

End: 1815364

Strand: Direct

Name: xylH [H]

Synonym: Bphy_1598

Alternate gene names: 186476356

Gene position: 1814207-1815364 (Clockwise)

Preceding gene: 186476355

Following gene: 186476357

Centisome position: 52.14

GC content: 62.78

Gene sequence:

>1158_bases
ATGGGCGTAGCCGGCAAACACTTTCCATCGCAACGTCACGACGCGAAGGGCAACGAGGCACAACCTGCAACCGCATCCGA
TGAACGCATCCGCAAAGAATCGTTCTTCGGACACGTACTCAACAGGCCGGAATTCGCCGCCATCTCCGGCACCGTACTGG
TGTTCCTCGTGTTCGCCATCACCGCGGGCAACTCGGGAATGTTCAACCTCGACGGCGTAATGAACTGGTCGCAGGTCTCC
GCGTATCTCGGCATTCTCGCCGTCGGCGCATGTCTGCTAATGATCGCCGGCGAGTTCGATCTCTCCATCGGCTCGATGAT
CGGCTTCGCAGGCATGATGGTCGCCATACCCGCCGTCTACTTTCACTGGCCGATCTGGGCGTCCATCATCTTCGCGTTCG
CCGGCTCCATGGCGCTCGGCGCGCTCAACGGCTACCTCGTGATGCGCACCCGCCTGCCGTCGTTCATCGTGACGCTCGCG
TTCCTCTTCATTCTGCGCGGCCTGACGCTCGCACTGTCAATCATGGTCGCGGACCGCACCATCATCTCCGGTGTCGGCGA
TCTCGCCCAGTCCGATGCCGTGACCAACTTCCTGTTTCATGGCGTCGCGCTGCACAGCCTCTTCACGAGCCTCGCGCACA
TGGGCATCGGCACGCTGCTCGACAACGGTCAGCCGCTCGTGCCAGGCATTCCGAAGGTGCTGCTGTGGTGGTTCGCGCTG
GCCGCCGTCGGTGCGTTCGTGCTCGCCAAGACGCGCTACGGCAACTGGATGCTCGCAGTCGGCGGCGATGCGAATGCCGC
CAAGAACGTCGGCGTGCCCGTGCGACGCGTGAAGATCTCGCTGTTCGTGCTGACAGCCTTCTGCTCGTGCCTCTTCGCGG
TGCTGCAAGTGTGCGATATCGGTTCCGCCGCCGCCGACCGCGGTCTGCAGAAGGAATTCGAGGCGATCATCGCCGCGGTC
ATCGGCGGCACACTGCTGACGGGCGGCTATGGATCAGTGGTGGGCGCCTGCTTCGGCGCGCTCATCTTCGGCGTCGTGCA
GATCGGCATCACCTATACGAATGTCAGTTCCGACTGGTTCCGCGTGTTCCTCGGCGTGATGCTGCTGATCGCCGTGCTCT
TCAATCACTATGTGCGCCGCCGCGTCGCGCAATCGTAA

Upstream 100 bases:

>100_bases
CCGAGTAAGCGCTAAAGCGCTAACTCGGATCGACCGCACTGACGTGCATGGGATCCGAGTAAGCGCTAAAGCGCTAACTC
GGATCGACACAGGAGACATC

Downstream 100 bases:

>100_bases
CGCCACGGGAGACGACCATGTCCGATACTCCGAACCAAGACGACACCATCCTCTCGCTCGAAAACGTCAGCAAGTACTTC
GGCAAGGTGATCGCACTGTC

Product: monosaccharide-transporting ATPase

Products: ADP; phosphate; xylose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 384

Protein sequence:

>385_residues
MGVAGKHFPSQRHDAKGNEAQPATASDERIRKESFFGHVLNRPEFAAISGTVLVFLVFAITAGNSGMFNLDGVMNWSQVS
AYLGILAVGACLLMIAGEFDLSIGSMIGFAGMMVAIPAVYFHWPIWASIIFAFAGSMALGALNGYLVMRTRLPSFIVTLA
FLFILRGLTLALSIMVADRTIISGVGDLAQSDAVTNFLFHGVALHSLFTSLAHMGIGTLLDNGQPLVPGIPKVLLWWFAL
AAVGAFVLAKTRYGNWMLAVGGDANAAKNVGVPVRRVKISLFVLTAFCSCLFAVLQVCDIGSAAADRGLQKEFEAIIAAV
IGGTLLTGGYGSVVGACFGALIFGVVQIGITYTNVSSDWFRVFLGVMLLIAVLFNHYVRRRVAQS

Sequences:

>Translated_385_residues
MGVAGKHFPSQRHDAKGNEAQPATASDERIRKESFFGHVLNRPEFAAISGTVLVFLVFAITAGNSGMFNLDGVMNWSQVS
AYLGILAVGACLLMIAGEFDLSIGSMIGFAGMMVAIPAVYFHWPIWASIIFAFAGSMALGALNGYLVMRTRLPSFIVTLA
FLFILRGLTLALSIMVADRTIISGVGDLAQSDAVTNFLFHGVALHSLFTSLAHMGIGTLLDNGQPLVPGIPKVLLWWFAL
AAVGAFVLAKTRYGNWMLAVGGDANAAKNVGVPVRRVKISLFVLTAFCSCLFAVLQVCDIGSAAADRGLQKEFEAIIAAV
IGGTLLTGGYGSVVGACFGALIFGVVQIGITYTNVSSDWFRVFLGVMLLIAVLFNHYVRRRVAQS
>Mature_384_residues
GVAGKHFPSQRHDAKGNEAQPATASDERIRKESFFGHVLNRPEFAAISGTVLVFLVFAITAGNSGMFNLDGVMNWSQVSA
YLGILAVGACLLMIAGEFDLSIGSMIGFAGMMVAIPAVYFHWPIWASIIFAFAGSMALGALNGYLVMRTRLPSFIVTLAF
LFILRGLTLALSIMVADRTIISGVGDLAQSDAVTNFLFHGVALHSLFTSLAHMGIGTLLDNGQPLVPGIPKVLLWWFALA
AVGAFVLAKTRYGNWMLAVGGDANAAKNVGVPVRRVKISLFVLTAFCSCLFAVLQVCDIGSAAADRGLQKEFEAIIAAVI
GGTLLTGGYGSVVGACFGALIFGVVQIGITYTNVSSDWFRVFLGVMLLIAVLFNHYVRRRVAQS

Specific function: Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. AraH/rbsC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789992, Length=369, Percent_Identity=29.2682926829268, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1788896, Length=337, Percent_Identity=28.7833827893175, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI87082395, Length=295, Percent_Identity=29.4915254237288, Blast_Score=111, Evalue=9e-26,
Organism=Escherichia coli, GI1790191, Length=329, Percent_Identity=28.5714285714286, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI145693152, Length=299, Percent_Identity=27.7591973244147, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1790524, Length=312, Percent_Identity=26.2820512820513, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787794, Length=324, Percent_Identity=26.2345679012346, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI145693214, Length=273, Percent_Identity=30.03663003663, Blast_Score=69, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 40955; Mature: 40824

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVAGKHFPSQRHDAKGNEAQPATASDERIRKESFFGHVLNRPEFAAISGTVLVFLVFAI
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
TAGNSGMFNLDGVMNWSQVSAYLGILAVGACLLMIAGEFDLSIGSMIGFAGMMVAIPAVY
HCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
FHWPIWASIIFAFAGSMALGALNGYLVMRTRLPSFIVTLAFLFILRGLTLALSIMVADRT
HHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IISGVGDLAQSDAVTNFLFHGVALHSLFTSLAHMGIGTLLDNGQPLVPGIPKVLLWWFAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
AAVGAFVLAKTRYGNWMLAVGGDANAAKNVGVPVRRVKISLFVLTAFCSCLFAVLQVCDI
HHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
GSAAADRGLQKEFEAIIAAVIGGTLLTGGYGSVVGACFGALIFGVVQIGITYTNVSSDWF
CCHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEECCCHHHH
RVFLGVMLLIAVLFNHYVRRRVAQS
HHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GVAGKHFPSQRHDAKGNEAQPATASDERIRKESFFGHVLNRPEFAAISGTVLVFLVFAI
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
TAGNSGMFNLDGVMNWSQVSAYLGILAVGACLLMIAGEFDLSIGSMIGFAGMMVAIPAVY
HCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
FHWPIWASIIFAFAGSMALGALNGYLVMRTRLPSFIVTLAFLFILRGLTLALSIMVADRT
HHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IISGVGDLAQSDAVTNFLFHGVALHSLFTSLAHMGIGTLLDNGQPLVPGIPKVLLWWFAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
AAVGAFVLAKTRYGNWMLAVGGDANAAKNVGVPVRRVKISLFVLTAFCSCLFAVLQVCDI
HHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
GSAAADRGLQKEFEAIIAAVIGGTLLTGGYGSVVGACFGALIFGVVQIGITYTNVSSDWF
CCHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEECCCHHHH
RVFLGVMLLIAVLFNHYVRRRVAQS
HHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; xylose [Periplasm]; H2O [C]

Specific reaction: ATP + xylose [Periplasm] + H2O = ADP + phosphate + xylose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]