Click here to switch to the map view.

The map label for this gene is codA [H]

Identifier: 186476235

GI number: 186476235

Start: 1666382

End: 1667671

Strand: Reverse

Name: codA [H]

Synonym: Bphy_1477

Alternate gene names: 186476235

Gene position: 1667671-1666382 (Counterclockwise)

Preceding gene: 186476237

Following gene: 186476228

Centisome position: 47.93

GC content: 64.26

Gene sequence:

>1290_bases
ATGGATCTGATCATCCGTCGTGCCGCATTGCCGCGCAGCGCCTCGCAACAGCGTGGCCTCGTCGACATTGGCATCGAGGC
AGGCCGCATCGTCGCGGTCGAGCCGAAGCTCGCGGCAACTGCGCGTGAGGAAATCGATGCCGACGGTGGGCTCGTCACGC
CGCCTTTCGTCGATGCGCATTTCCACATGGACGCGACGCTGTCATATGGTCTGCCGCGTGTGAACGCGTCGGGCACCTTA
CTCGAAGGCATCGCGCTATGGGGCGAACTGAAGCCGCATCTGACGCAGGAGGCGCTGGTCGAGCGTGCGCTGCAATATTG
CGATTGGGCCGTCGCGCGCGGGTTGCTGGCCATCCGCACGCATGTCGACGTGTGCGACGAGCGTCTCTTTGCCGTCGAAG
CGCTGCTTGAGGTGAAGCGCCGCGTCGCGCCTTATCTGGTTCTGCAACTGGTTGCGTTTCCGCAAGACGGCCTGCTGCGC
AGCGCCGGCGCGTTCGACAACCTCAAGCGCGCGATCGCGATGGGCGTCGACGTGGTCGGTGGCATCCCGCATTTCGAACG
AACGATGGCGGACGGCGCCGAGTCGGTGCGGCTGCTCTGCGAGTTCGCCGCGCAGAAGGGCTTGCGCGTCGACATGCATT
GCGACGAATCCGACGATCCGATGTCGCGTCACATCGAAACGCTCGCCGCGCAAGCCCATCGGCTAGGCCTGCACGGACGC
GTGACGGGTTCGCATCTGACGTCGATGCATTCGATGGACAACTACTACGTCAGCAAGCTGCTGCCGTTGATGCGCGAATC
GGGCGTAGCGGCCATTGCGAACCCGCTCATCAACATCACGTTGCAGGGGCGCTCGGACACCTATCCGAAGCGGCGCGGTA
TGACGCGCGTGCCCGAGATGCTGGAGGCGGGAATCAATGTTGCGTTCGGCCACGACTGCGTGATGGACCCGTGGTACAGC
CTCGGCTCAGGCGACATGCTGGAAGTCGCGCATATGGGGTTGCACGTCGCGCAGATGACGGGCATCGACGCGATGCACAC
GTGCTTCGATGCCGTCACGGTGAACGCGGCGCGTATCCTGGGGTTGGAGCGTTATGGAATTGAGCCGGGATCCGACGCGA
ATCTTGTCTTGCTCGACGCACGCGACGCCGTCGAAGCGATACGCCTGCGCGCGGCGAGGCGCGCGGTGGTGAGTCGAGGG
AAAGTCGTTAGCCGTGCGCCGGCAGCACGCGCGTCGTTATCGCTGGAAGGGCGGCCAACGGAAGTGGACTTCAAGCTGCA
TCGCGAATGA

Upstream 100 bases:

>100_bases
CCAGGTCTCCCAACGACACGCATTTCTTCCTATGCCGTTGCGTTGGTCCACAAGCATTTCTTCCGCCGATAGAATCGATG
TCATGCAAAGGGAGCCCCTC

Downstream 100 bases:

>100_bases
AAAGGCGAGTTCGGTAAAACCGAGCCCGCTTCGCGTGTGCCCGAACGCCGACCTGATCGAAGCGCCGGAAGATGCAGGCG
CTTCGACAGGCGGCGGCTGA

Product: cytosine deaminase

Products: NA

Alternate protein names: Cytosine aminohydrolase [H]

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MDLIIRRAALPRSASQQRGLVDIGIEAGRIVAVEPKLAATAREEIDADGGLVTPPFVDAHFHMDATLSYGLPRVNASGTL
LEGIALWGELKPHLTQEALVERALQYCDWAVARGLLAIRTHVDVCDERLFAVEALLEVKRRVAPYLVLQLVAFPQDGLLR
SAGAFDNLKRAIAMGVDVVGGIPHFERTMADGAESVRLLCEFAAQKGLRVDMHCDESDDPMSRHIETLAAQAHRLGLHGR
VTGSHLTSMHSMDNYYVSKLLPLMRESGVAAIANPLINITLQGRSDTYPKRRGMTRVPEMLEAGINVAFGHDCVMDPWYS
LGSGDMLEVAHMGLHVAQMTGIDAMHTCFDAVTVNAARILGLERYGIEPGSDANLVLLDARDAVEAIRLRAARRAVVSRG
KVVSRAPAARASLSLEGRPTEVDFKLHRE

Sequences:

>Translated_429_residues
MDLIIRRAALPRSASQQRGLVDIGIEAGRIVAVEPKLAATAREEIDADGGLVTPPFVDAHFHMDATLSYGLPRVNASGTL
LEGIALWGELKPHLTQEALVERALQYCDWAVARGLLAIRTHVDVCDERLFAVEALLEVKRRVAPYLVLQLVAFPQDGLLR
SAGAFDNLKRAIAMGVDVVGGIPHFERTMADGAESVRLLCEFAAQKGLRVDMHCDESDDPMSRHIETLAAQAHRLGLHGR
VTGSHLTSMHSMDNYYVSKLLPLMRESGVAAIANPLINITLQGRSDTYPKRRGMTRVPEMLEAGINVAFGHDCVMDPWYS
LGSGDMLEVAHMGLHVAQMTGIDAMHTCFDAVTVNAARILGLERYGIEPGSDANLVLLDARDAVEAIRLRAARRAVVSRG
KVVSRAPAARASLSLEGRPTEVDFKLHRE
>Mature_429_residues
MDLIIRRAALPRSASQQRGLVDIGIEAGRIVAVEPKLAATAREEIDADGGLVTPPFVDAHFHMDATLSYGLPRVNASGTL
LEGIALWGELKPHLTQEALVERALQYCDWAVARGLLAIRTHVDVCDERLFAVEALLEVKRRVAPYLVLQLVAFPQDGLLR
SAGAFDNLKRAIAMGVDVVGGIPHFERTMADGAESVRLLCEFAAQKGLRVDMHCDESDDPMSRHIETLAAQAHRLGLHGR
VTGSHLTSMHSMDNYYVSKLLPLMRESGVAAIANPLINITLQGRSDTYPKRRGMTRVPEMLEAGINVAFGHDCVMDPWYS
LGSGDMLEVAHMGLHVAQMTGIDAMHTCFDAVTVNAARILGLERYGIEPGSDANLVLLDARDAVEAIRLRAARRAVVSRG
KVVSRAPAARASLSLEGRPTEVDFKLHRE

Specific function: Unknown

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786531, Length=411, Percent_Identity=46.7153284671533, Blast_Score=384, Evalue=1e-108,
Organism=Escherichia coli, GI1786517, Length=398, Percent_Identity=27.8894472361809, Blast_Score=87, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013108
- InterPro:   IPR011059 [H]

Pfam domain/function: PF07969 Amidohydro_3 [H]

EC number: =3.5.4.1 [H]

Molecular weight: Translated: 46750; Mature: 46750

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: PS01137 TATD_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLIIRRAALPRSASQQRGLVDIGIEAGRIVAVEPKLAATAREEIDADGGLVTPPFVDAH
CCCCHHHHCCCCCCHHHCCCEEECCCCCEEEEECCHHHHHHHHHHCCCCCCCCCCCCCCE
FHMDATLSYGLPRVNASGTLLEGIALWGELKPHLTQEALVERALQYCDWAVARGLLAIRT
EEECCHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
HVDVCDERLFAVEALLEVKRRVAPYLVLQLVAFPQDGLLRSAGAFDNLKRAIAMGVDVVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHHHHC
GIPHFERTMADGAESVRLLCEFAAQKGLRVDMHCDESDDPMSRHIETLAAQAHRLGLHGR
CCCHHHHHHHCCHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCE
VTGSHLTSMHSMDNYYVSKLLPLMRESGVAAIANPLINITLQGRSDTYPKRRGMTRVPEM
ECHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCEEEEEECCCCCCCHHHCCCHHHHHH
LEAGINVAFGHDCVMDPWYSLGSGDMLEVAHMGLHVAQMTGIDAMHTCFDAVTVNAARIL
HHCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
GLERYGIEPGSDANLVLLDARDAVEAIRLRAARRAVVSRGKVVSRAPAARASLSLEGRPT
HHHHHCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHCEEEECCCCC
EVDFKLHRE
EECEEEECC
>Mature Secondary Structure
MDLIIRRAALPRSASQQRGLVDIGIEAGRIVAVEPKLAATAREEIDADGGLVTPPFVDAH
CCCCHHHHCCCCCCHHHCCCEEECCCCCEEEEECCHHHHHHHHHHCCCCCCCCCCCCCCE
FHMDATLSYGLPRVNASGTLLEGIALWGELKPHLTQEALVERALQYCDWAVARGLLAIRT
EEECCHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
HVDVCDERLFAVEALLEVKRRVAPYLVLQLVAFPQDGLLRSAGAFDNLKRAIAMGVDVVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHHHHC
GIPHFERTMADGAESVRLLCEFAAQKGLRVDMHCDESDDPMSRHIETLAAQAHRLGLHGR
CCCHHHHHHHCCHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCE
VTGSHLTSMHSMDNYYVSKLLPLMRESGVAAIANPLINITLQGRSDTYPKRRGMTRVPEM
ECHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCEEEEEECCCCCCCHHHCCCHHHHHH
LEAGINVAFGHDCVMDPWYSLGSGDMLEVAHMGLHVAQMTGIDAMHTCFDAVTVNAARIL
HHCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
GLERYGIEPGSDANLVLLDARDAVEAIRLRAARRAVVSRGKVVSRAPAARASLSLEGRPT
HHHHHCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHCEEEECCCCC
EVDFKLHRE
EECEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1640834; 8450832; 9278503 [H]