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The map label for this gene is aceE [H]

Identifier: 186476228

GI number: 186476228

Start: 1653718

End: 1656417

Strand: Reverse

Name: aceE [H]

Synonym: Bphy_1470

Alternate gene names: 186476228

Gene position: 1656417-1653718 (Counterclockwise)

Preceding gene: 186476235

Following gene: 186476227

Centisome position: 47.61

GC content: 62.56

Gene sequence:

>2700_bases
ATGTCCGCTGTACCTGACGAAGTGATGAAGTACGTCGCCAACGCCAAAGACGATAGCGACCCGCAAGAAACGGCCGAGTG
GCTCGAAGCGCTTGATGGCGTGATTTCTGCTGTCGGACCCGACCGCGCTCACTACCTCATCGAAAAGCAGATCGAATTTG
CACGCGTGCATGGCGAGCATCTGCCTTTCTCTGCGAACACCCCGTACATCAATACGATCCCCGTCGCGAATCAGGCGAAG
ATTCCGGGCGACCAGGACGTCGAACACCGCATCCGCTCGTACACGCGCTGGAACGCGATGGCGATGGTGCTGCGCGCTGG
CAAGGACACCAACGTCGGCGGCCACATCGCATCGTTCGCCTCGGCCGCGACGCTGTACGACGTCGGCTTCAACCACTTCT
GGCACGCGCCGTCGAAAGATCACGGCGGCGACCTCGTGTTCGTGCAGGGCCACTCGTCGCCGGGCGTCTACTCGCGCGCG
TTCCTGCTCGGCCGACTGTCGGAGAACCAGCTCGACAACTTCCGTCAGGAAGTGGGCGGCGAGGGCATCTCGTCGTACCC
GCATCCCTGGCTGATGCCGGACTTCTGGCAGTTCCCGACGGTGTCGATGGGTCTCGGCCCGATCATGGCGATCTATCAGG
CCCGCTTCATGAAGTACCTGCAGGCGCGCGGCATCGCGAAGACCGACGGCCGCAAAGTGTGGGCGTTCCTCGGCGACGGC
GAAACGGATGAACCGGAATCGCTCGGTGCAATCGGCATGGCCGGCCGCGAGCGTCTCGACAACCTCGTGTTCGTCATCAA
CTGCAACCTGCAGCGCCTCGACGGCCCGGTGCGCGGCAACGGCAAAATCATTCAGGAACTCGAAAGCGAGTTCCGCGGCG
CCGGCTGGAACGTCATCAAGGTGGTCTGGGGCAGCCGCTGGGATGCCCTGTTCGCACGCGACAAGTCGGGCGCACTGATG
CGCCGGATGATGGAAGTCGTCGACGGCGAATATCAGACGTACAAGTCCGAGTCGGGCGCGTTCGTTCGCGAGCACTTCTT
CAACACGCCCGAACTGAAGGCGCTGGTTGCCGACTGGTCCGATGACGATGTGTGGAGCCTGAACCGCGGCGGCCACGATC
CGCACAAGATCTACGCGGCGTTCAAGCAGGCGACGCAGGCGCAGGGCCAGCCGACTGTGATACTCGCGAAGACGATCAAG
GGCTACGGCATGGGCGAAGCCGGCCAGGCGATGAACATCACCCACCAGCAGAAGAAGATGCAGGTGGAAGCGCTCAAGCA
TTTCCGCGACCAGTTCCGCCTGCCCATTTCGGACGACGAGATTGCGCACGTGCCGTATCTGAAGTTCGAGGAAGGCTCGA
AGGAACTTGAATACATGCGCGCCCGCCGCCAGGAACTGGGCGGCTATCTGCCGGCGCGCCGCCAGAAGGCGGAATCGCTG
CCCGTTCCGGGGCTCGACGCATTCGAGCCGCTGCTGAAGGGCACGGGCGAAGGCCGCGAAATTTCCACGACGATGGCGTT
CGTGCGGATTCTCAACATCGTGTTGAAGGACAAGGCAATCGGCAAGCGCGTCGTGCCCATCGTGCCGGACGAGTCGCGTA
CCTTCGGCATGGAAGGTCTGTTCCGCCAGATCGGCATCTGGAATCAGGACGGCCAGAAGTACATCCCGGAAGATTCCGAC
CAGCTGATGTTCTACCGTGAGTCGGAAACGGGCCAGATCCTGCAGGAAGGCATCAACGAAGCAGGCGGCATGTCGGACTG
GATCGCAGCGGCGACGTCGTATTCGACGCACGGCGAGATCATGATCCCGTTCTACATCTTCTACTCGATGTTCGGCATGC
AGCGCATCGGCGACCTGGTGTGGGCCGCAGGCGACATGCGTTCGCGCGGCTTCCTGTTGGGCGGCACGGCGGGCCGGACG
ACGCTCAACGGCGAAGGCCTGCAGCACGAAGACGGCCACTCGCTGCTGTGGGCTGCATCGGTGCCGAACTGCCTGAGCTA
TGACCCGACGTTTGGCTACGAACTCGCTGTCATCATGCAGGACGGTCTGCGCCGCATGGTGCAGGAACAGGAAGACGTGT
TCTATTACATCACGGTGATGAATGAGAACTACGAGCACCCGGCGATCCCGCAGGGCGAGCACGTGGCGAAGGACATCATC
AAGGGGATGTACGCGTTCCGCAAGGGCGCCGACAACGCGAAGGCGCCGCGCGTGCAGCTGATGGGCGCGGGCACGATCTT
CAACGAAGTGATCGCCGCCGCCGACCTGCTGAAGAACGACTGGGGCGTCGAAGCCGACCTGTGGAGCGTGCCGAGCTTCA
CGGAACTGGCGCGCGAAGGTCACGAAGTGCAGCGTCAAAACCTGCTGAACCCGCTCGCCGAAAAGAAGCTCTCGCATGTC
GAGACGCTGCTGAAGGACGCAAAGGGTCCTGTGATCGCGTCGACCGACTACGTCCGAGCGCTGGTCGACCAGATCCGTGC
GTTTGTCCCGCAACGCTTCGTCGTGCTGGGCACCGACGGTTTCGGCCGCTCGGACACGCGCGAAAAGCTGCGTCACTTCT
TTGAAGTCGACCGCTACTGGACGACGGTTGCTGCGCTGAATGCGCTGGCCGATGAGGGTACGATTGAGCGCAAGGTGGTG
GCCGACGCGCTGAAGAAGTACAACCTCGATCCGTCCAAACCCAACCCGATGACCGTCTAA

Upstream 100 bases:

>100_bases
CAGGCGTTGTGGGCCTTATTACAATCGCCCGGAAGCTGCCGCGGTCGCCGTTCGTCCGCGTCGCCTGTTCACAGAGCGTT
CCCATATCCAGGAGACGAGC

Downstream 100 bases:

>100_bases
GGCATCGACCCGCGAGCCCCAATGTGTACCTCGCCGCCCGAAGCGGGCGGCGAGGTGCGCGCGGCCCTGGAGACAGAAAA
CAATGAGCCAAGCGATCGAA

Product: pyruvate dehydrogenase subunit E1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 899; Mature: 898

Protein sequence:

>899_residues
MSAVPDEVMKYVANAKDDSDPQETAEWLEALDGVISAVGPDRAHYLIEKQIEFARVHGEHLPFSANTPYINTIPVANQAK
IPGDQDVEHRIRSYTRWNAMAMVLRAGKDTNVGGHIASFASAATLYDVGFNHFWHAPSKDHGGDLVFVQGHSSPGVYSRA
FLLGRLSENQLDNFRQEVGGEGISSYPHPWLMPDFWQFPTVSMGLGPIMAIYQARFMKYLQARGIAKTDGRKVWAFLGDG
ETDEPESLGAIGMAGRERLDNLVFVINCNLQRLDGPVRGNGKIIQELESEFRGAGWNVIKVVWGSRWDALFARDKSGALM
RRMMEVVDGEYQTYKSESGAFVREHFFNTPELKALVADWSDDDVWSLNRGGHDPHKIYAAFKQATQAQGQPTVILAKTIK
GYGMGEAGQAMNITHQQKKMQVEALKHFRDQFRLPISDDEIAHVPYLKFEEGSKELEYMRARRQELGGYLPARRQKAESL
PVPGLDAFEPLLKGTGEGREISTTMAFVRILNIVLKDKAIGKRVVPIVPDESRTFGMEGLFRQIGIWNQDGQKYIPEDSD
QLMFYRESETGQILQEGINEAGGMSDWIAAATSYSTHGEIMIPFYIFYSMFGMQRIGDLVWAAGDMRSRGFLLGGTAGRT
TLNGEGLQHEDGHSLLWAASVPNCLSYDPTFGYELAVIMQDGLRRMVQEQEDVFYYITVMNENYEHPAIPQGEHVAKDII
KGMYAFRKGADNAKAPRVQLMGAGTIFNEVIAAADLLKNDWGVEADLWSVPSFTELAREGHEVQRQNLLNPLAEKKLSHV
ETLLKDAKGPVIASTDYVRALVDQIRAFVPQRFVVLGTDGFGRSDTREKLRHFFEVDRYWTTVAALNALADEGTIERKVV
ADALKKYNLDPSKPNPMTV

Sequences:

>Translated_899_residues
MSAVPDEVMKYVANAKDDSDPQETAEWLEALDGVISAVGPDRAHYLIEKQIEFARVHGEHLPFSANTPYINTIPVANQAK
IPGDQDVEHRIRSYTRWNAMAMVLRAGKDTNVGGHIASFASAATLYDVGFNHFWHAPSKDHGGDLVFVQGHSSPGVYSRA
FLLGRLSENQLDNFRQEVGGEGISSYPHPWLMPDFWQFPTVSMGLGPIMAIYQARFMKYLQARGIAKTDGRKVWAFLGDG
ETDEPESLGAIGMAGRERLDNLVFVINCNLQRLDGPVRGNGKIIQELESEFRGAGWNVIKVVWGSRWDALFARDKSGALM
RRMMEVVDGEYQTYKSESGAFVREHFFNTPELKALVADWSDDDVWSLNRGGHDPHKIYAAFKQATQAQGQPTVILAKTIK
GYGMGEAGQAMNITHQQKKMQVEALKHFRDQFRLPISDDEIAHVPYLKFEEGSKELEYMRARRQELGGYLPARRQKAESL
PVPGLDAFEPLLKGTGEGREISTTMAFVRILNIVLKDKAIGKRVVPIVPDESRTFGMEGLFRQIGIWNQDGQKYIPEDSD
QLMFYRESETGQILQEGINEAGGMSDWIAAATSYSTHGEIMIPFYIFYSMFGMQRIGDLVWAAGDMRSRGFLLGGTAGRT
TLNGEGLQHEDGHSLLWAASVPNCLSYDPTFGYELAVIMQDGLRRMVQEQEDVFYYITVMNENYEHPAIPQGEHVAKDII
KGMYAFRKGADNAKAPRVQLMGAGTIFNEVIAAADLLKNDWGVEADLWSVPSFTELAREGHEVQRQNLLNPLAEKKLSHV
ETLLKDAKGPVIASTDYVRALVDQIRAFVPQRFVVLGTDGFGRSDTREKLRHFFEVDRYWTTVAALNALADEGTIERKVV
ADALKKYNLDPSKPNPMTV
>Mature_898_residues
SAVPDEVMKYVANAKDDSDPQETAEWLEALDGVISAVGPDRAHYLIEKQIEFARVHGEHLPFSANTPYINTIPVANQAKI
PGDQDVEHRIRSYTRWNAMAMVLRAGKDTNVGGHIASFASAATLYDVGFNHFWHAPSKDHGGDLVFVQGHSSPGVYSRAF
LLGRLSENQLDNFRQEVGGEGISSYPHPWLMPDFWQFPTVSMGLGPIMAIYQARFMKYLQARGIAKTDGRKVWAFLGDGE
TDEPESLGAIGMAGRERLDNLVFVINCNLQRLDGPVRGNGKIIQELESEFRGAGWNVIKVVWGSRWDALFARDKSGALMR
RMMEVVDGEYQTYKSESGAFVREHFFNTPELKALVADWSDDDVWSLNRGGHDPHKIYAAFKQATQAQGQPTVILAKTIKG
YGMGEAGQAMNITHQQKKMQVEALKHFRDQFRLPISDDEIAHVPYLKFEEGSKELEYMRARRQELGGYLPARRQKAESLP
VPGLDAFEPLLKGTGEGREISTTMAFVRILNIVLKDKAIGKRVVPIVPDESRTFGMEGLFRQIGIWNQDGQKYIPEDSDQ
LMFYRESETGQILQEGINEAGGMSDWIAAATSYSTHGEIMIPFYIFYSMFGMQRIGDLVWAAGDMRSRGFLLGGTAGRTT
LNGEGLQHEDGHSLLWAASVPNCLSYDPTFGYELAVIMQDGLRRMVQEQEDVFYYITVMNENYEHPAIPQGEHVAKDIIK
GMYAFRKGADNAKAPRVQLMGAGTIFNEVIAAADLLKNDWGVEADLWSVPSFTELAREGHEVQRQNLLNPLAEKKLSHVE
TLLKDAKGPVIASTDYVRALVDQIRAFVPQRFVVLGTDGFGRSDTREKLRHFFEVDRYWTTVAALNALADEGTIERKVVA
DALKKYNLDPSKPNPMTV

Specific function: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components:pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydroge

COG id: COG2609

COG function: function code C; Pyruvate dehydrogenase complex, dehydrogenase (E1) component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786304, Length=886, Percent_Identity=59.0293453724605, Blast_Score=1074, Evalue=0.0,

Paralogues:

None

Copy number: 1140 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 400 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004660
- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005474 [H]

Pfam domain/function: PF00456 Transketolase_N [H]

EC number: =1.2.4.1 [H]

Molecular weight: Translated: 100610; Mature: 100479

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAVPDEVMKYVANAKDDSDPQETAEWLEALDGVISAVGPDRAHYLIEKQIEFARVHGEH
CCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCC
LPFSANTPYINTIPVANQAKIPGDQDVEHRIRSYTRWNAMAMVLRAGKDTNVGGHIASFA
CCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
SAATLYDVGFNHFWHAPSKDHGGDLVFVQGHSSPGVYSRAFLLGRLSENQLDNFRQEVGG
HHHHHHHCCHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHCC
EGISSYPHPWLMPDFWQFPTVSMGLGPIMAIYQARFMKYLQARGIAKTDGRKVWAFLGDG
CCCCCCCCCCCCCCCCCCCCCHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCC
ETDEPESLGAIGMAGRERLDNLVFVINCNLQRLDGPVRGNGKIIQELESEFRGAGWNVIK
CCCCCHHCCHHCHHHHHHHCCEEEEEECCHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEE
VVWGSRWDALFARDKSGALMRRMMEVVDGEYQTYKSESGAFVREHFFNTPELKALVADWS
EEECCCCHHHHCCCCCCHHHHHHHHHHCCHHHHHCCCCCCHHHHHCCCCCHHHHHEECCC
DDDVWSLNRGGHDPHKIYAAFKQATQAQGQPTVILAKTIKGYGMGEAGQAMNITHQQKKM
CCCCEECCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHH
QVEALKHFRDQFRLPISDDEIAHVPYLKFEEGSKELEYMRARRQELGGYLPARRQKAESL
HHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHCC
PVPGLDAFEPLLKGTGEGREISTTMAFVRILNIVLKDKAIGKRVVPIVPDESRTFGMEGL
CCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHH
FRQIGIWNQDGQKYIPEDSDQLMFYRESETGQILQEGINEAGGMSDWIAAATSYSTHGEI
HHHCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCE
MIPFYIFYSMFGMQRIGDLVWAAGDMRSRGFLLGGTAGRTTLNGEGLQHEDGHSLLWAAS
EHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCEECCCCCCCCCCCCEEEECC
VPNCLSYDPTFGYELAVIMQDGLRRMVQEQEDVFYYITVMNENYEHPAIPQGEHVAKDII
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHH
KGMYAFRKGADNAKAPRVQLMGAGTIFNEVIAAADLLKNDWGVEADLWSVPSFTELAREG
HHHHHHHCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHH
HEVQRQNLLNPLAEKKLSHVETLLKDAKGPVIASTDYVRALVDQIRAFVPQRFVVLGTDG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHCCCCEEEEECCC
FGRSDTREKLRHFFEVDRYWTTVAALNALADEGTIERKVVADALKKYNLDPSKPNPMTV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
SAVPDEVMKYVANAKDDSDPQETAEWLEALDGVISAVGPDRAHYLIEKQIEFARVHGEH
CCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCC
LPFSANTPYINTIPVANQAKIPGDQDVEHRIRSYTRWNAMAMVLRAGKDTNVGGHIASFA
CCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
SAATLYDVGFNHFWHAPSKDHGGDLVFVQGHSSPGVYSRAFLLGRLSENQLDNFRQEVGG
HHHHHHHCCHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHCC
EGISSYPHPWLMPDFWQFPTVSMGLGPIMAIYQARFMKYLQARGIAKTDGRKVWAFLGDG
CCCCCCCCCCCCCCCCCCCCCHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCC
ETDEPESLGAIGMAGRERLDNLVFVINCNLQRLDGPVRGNGKIIQELESEFRGAGWNVIK
CCCCCHHCCHHCHHHHHHHCCEEEEEECCHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEE
VVWGSRWDALFARDKSGALMRRMMEVVDGEYQTYKSESGAFVREHFFNTPELKALVADWS
EEECCCCHHHHCCCCCCHHHHHHHHHHCCHHHHHCCCCCCHHHHHCCCCCHHHHHEECCC
DDDVWSLNRGGHDPHKIYAAFKQATQAQGQPTVILAKTIKGYGMGEAGQAMNITHQQKKM
CCCCEECCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHH
QVEALKHFRDQFRLPISDDEIAHVPYLKFEEGSKELEYMRARRQELGGYLPARRQKAESL
HHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHCC
PVPGLDAFEPLLKGTGEGREISTTMAFVRILNIVLKDKAIGKRVVPIVPDESRTFGMEGL
CCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHH
FRQIGIWNQDGQKYIPEDSDQLMFYRESETGQILQEGINEAGGMSDWIAAATSYSTHGEI
HHHCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCE
MIPFYIFYSMFGMQRIGDLVWAAGDMRSRGFLLGGTAGRTTLNGEGLQHEDGHSLLWAAS
EHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCEECCCCCCCCCCCCEEEECC
VPNCLSYDPTFGYELAVIMQDGLRRMVQEQEDVFYYITVMNENYEHPAIPQGEHVAKDII
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHH
KGMYAFRKGADNAKAPRVQLMGAGTIFNEVIAAADLLKNDWGVEADLWSVPSFTELAREG
HHHHHHHCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHH
HEVQRQNLLNPLAEKKLSHVETLLKDAKGPVIASTDYVRALVDQIRAFVPQRFVVLGTDG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHCCCCEEEEECCC
FGRSDTREKLRHFFEVDRYWTTVAALNALADEGTIERKVVADALKKYNLDPSKPNPMTV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8021225 [H]