Click here to switch to the map view.

The map label for this gene is dctS [H]

Identifier: 186476229

GI number: 186476229

Start: 1656683

End: 1659208

Strand: Direct

Name: dctS [H]

Synonym: Bphy_1471

Alternate gene names: 186476229

Gene position: 1656683-1659208 (Clockwise)

Preceding gene: 186476225

Following gene: 186476230

Centisome position: 47.62

GC content: 64.05

Gene sequence:

>2526_bases
ATGCGAGCCATGTTGACCGATCGACTTTTCGCACGCTCGGCACGCTCTGCCGGACCGTCGGCGGATTCGTCGCCGTCACG
CTGGCACCACGGACCTTGGTGGTCGAATTCCTATTTGCTGACGCCGCTGCTGTCGATCCTGGTCTTCCTGGTCGTCATGA
GCCTGATCCTGTGGAGCCTGAACCGGCGAGAACAGCAACAGCAGGAAGACACGCTTTATCGCAACGTCGCGTGGGCGCAG
CAGCAAATCCGCCTCTCGATGACGGGCGCGCAGGAACAGCTTCAGGCGCTCGCGCGCGACCTGGTTTCGGGCCGCGCGGA
CCCGCACTCCTTCCAGGTGTCGACGGCCGACATCATGCAGGGGCATCCCGAGATCCTCTACATGAACTGGTACACCAGCG
CGCAGCAGCCGCGCTGGCCGAACAACGCGTTGCCCGTGCTGGGCCAGCGCCTTGCCAAGCCCAATGACCAGCAGATGGAC
GAGGCCGTCAAGGCGGCCTTCGCCGAAGCGAAGAACACGCGCCGCCAGGTCTACTCGCCGCTGATGTACGACGACGTCGG
CAATGGCTACATCACCCTGCAAACACCCGTTTATCGCGACCGCGACTTTCTCGGCACAGTCGCGGCCGTGTTCTCGATCG
AAGGGATCCTGAAGCGCGACATCCCACCGGAGCTGTCCGCGAAGTACAAGATCTCGATCATCGACATCAACAACCGCGAG
CTCGCCACCACCTCGACGCGCCCCCGCCTGCCGCGCGACGCATACTACGACCTGCCCCTCGACCCGCCCGGCCAGGGCGT
GTCGGTGCGCGTCTATGCGTATCCGCAGATGACCAACTTCACGAACAACACGCTCGTGTGGCTGGTCGCGGGTCTGTCGT
GTTTTGTCCTGTGGAGCCTGTGGAGTCTGTGGAAGCACACGCGCCAGCGCTTCGAGGCGCAACAGGCGCTGTACGCGGAA
GCGTTTTTCCGCCGCGCGATGGAAAACTCCGTGCTGATCGGCATGCGCGTGCTCGATATGCATGGGCGCATCACGCACGT
GAACCCCGCCTTCTGCCGCATGACGGGCTGGGACGAAAGCGATCTGGTGGGCAAGAATGCACCGTTCCCGTACTGGCCGC
GCGACTCGTATCCCGAGATGCAGCGTCAGCTCGACATGACCTTGCGCGGCAAGGCGCCTTCGTCCGGCTTCGAGCTGCGC
GTGCGCCGCAAGGACGGCTCCCTGTTCCACGCACGCCTGTACGTGTCGCCGCTGATCGACAGCTCGGGCCGACAGACGGG
CTGGATGTCGTCGATGACGGACATCACAGAGCCGAAGCGCGCTCGCGAAGAACTCGCCGCCGCGCACGAGCGCTTCACGA
CGGTGCTCGAAAGCCTCGATGCCGCCGTGTCCGTGCTCGCCGCCGACGAAGCCGAGCTGCTGTTCGCGAATCGCTATTAC
CGCCACCTGTTCGGCATCCGCCCCGACGGCCATCTCGAACTCGCGGGAGGCGGCGGCTTCGACAGTTCGGCGGCCTCGTC
GGATTCGATCGACATGGTCGACGCGTTCGCCGGCCTGCCCGCCACCGCGCTCACGGAAAGCACGGCCGACGCGCAGGAAG
TCTACGTGCAGGGGATCCAGAAGTGGTTCGAAGTGCGACGCCAGTACATCCAGTGGGTGGACGGCCATCTCGCGCAGATG
CAGATTGCGACCGACATCACCACCCGCAAGCAGGCGCAGGAACTGGCGCGCCAGCAGGACGAGAAGCTGCAGTTCACGAG
CCGCCTGATGACGATGGGCGAAATGGCGTCGTCGCTCGCGCACGAACTAAACCAGCCTCTTGCGGCCATCAATAACTATT
GCTCTGGAACCGTCGCACTGGTTAAATCTGGTCGGACGACTCCCGACAACCTGCTACCTGTGCTCGAAAAGACGGCGCAA
CAAGCCGTGCGGGCCGGCATGATCATCAAGCGCATCCGCGAATTCGTGAAACGCAGCGAACCGAAACGCCAGGCCACCCG
GGTCTCCGACATCGTCGCGGACGCCGTGGGCCTTGCCGAGATCGAAGCGCGCAAGCGCCGCATCCGCATCGTGACGGACA
TGCGCTCGCGTCTGCCCGTGATCTACGTCGACCCCGTGCTGATCGAACAGGTGCTCGTCAACCTGCTGAAGAACGCGGCG
GAAGCCATGCACGACGCGCGCCCCGACGCCGTCGATCCCGTCATCCGCGTCGTCGTGAAGCTCGATTCCGGCTTCGTGTG
CATCAGCGTCGTCGACCAGGGTCCGGGCGTCGACGAAGCCACGGCCGAACGTCTCTTCGAACCGTTTTACAGCACCAAGT
CCGACGGCATGGGCATGGGGCTGAACATTTGCCGTTCGATCATCGAATCGCATCGCGGACGCCTGTGGGTGGTCAACAAC
GTCGAGTCCGACGGCCACATCACGGGTGCCACTTTCCATTGCAGTCTGCCTATTGGAGAGCCTGACGGCCCGAGCAACGG
CGGGTCCGAGGCGCCGACACCACAAACCGTTACGGGAGAGCTATGA

Upstream 100 bases:

>100_bases
GGTTTGACTGCCGATCAGCGAGTACGTCGGCTAGTTTGCGCCGAATTGCGTGACTTTCATCGCTTTTTTGCGGCAATTAC
GTGTCAGCCCCTGCGCTACA

Downstream 100 bases:

>100_bases
ACACCCCAGTTACCACACAGGAAACCGTGTTTGTCGTCGACGACGACGAAGCGGTGCGAGATTCGCTGCGCTGGCTGCTG
GAAGCAAACGGCTACCGCGT

Product: multi-sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 841; Mature: 841

Protein sequence:

>841_residues
MRAMLTDRLFARSARSAGPSADSSPSRWHHGPWWSNSYLLTPLLSILVFLVVMSLILWSLNRREQQQQEDTLYRNVAWAQ
QQIRLSMTGAQEQLQALARDLVSGRADPHSFQVSTADIMQGHPEILYMNWYTSAQQPRWPNNALPVLGQRLAKPNDQQMD
EAVKAAFAEAKNTRRQVYSPLMYDDVGNGYITLQTPVYRDRDFLGTVAAVFSIEGILKRDIPPELSAKYKISIIDINNRE
LATTSTRPRLPRDAYYDLPLDPPGQGVSVRVYAYPQMTNFTNNTLVWLVAGLSCFVLWSLWSLWKHTRQRFEAQQALYAE
AFFRRAMENSVLIGMRVLDMHGRITHVNPAFCRMTGWDESDLVGKNAPFPYWPRDSYPEMQRQLDMTLRGKAPSSGFELR
VRRKDGSLFHARLYVSPLIDSSGRQTGWMSSMTDITEPKRAREELAAAHERFTTVLESLDAAVSVLAADEAELLFANRYY
RHLFGIRPDGHLELAGGGGFDSSAASSDSIDMVDAFAGLPATALTESTADAQEVYVQGIQKWFEVRRQYIQWVDGHLAQM
QIATDITTRKQAQELARQQDEKLQFTSRLMTMGEMASSLAHELNQPLAAINNYCSGTVALVKSGRTTPDNLLPVLEKTAQ
QAVRAGMIIKRIREFVKRSEPKRQATRVSDIVADAVGLAEIEARKRRIRIVTDMRSRLPVIYVDPVLIEQVLVNLLKNAA
EAMHDARPDAVDPVIRVVVKLDSGFVCISVVDQGPGVDEATAERLFEPFYSTKSDGMGMGLNICRSIIESHRGRLWVVNN
VESDGHITGATFHCSLPIGEPDGPSNGGSEAPTPQTVTGEL

Sequences:

>Translated_841_residues
MRAMLTDRLFARSARSAGPSADSSPSRWHHGPWWSNSYLLTPLLSILVFLVVMSLILWSLNRREQQQQEDTLYRNVAWAQ
QQIRLSMTGAQEQLQALARDLVSGRADPHSFQVSTADIMQGHPEILYMNWYTSAQQPRWPNNALPVLGQRLAKPNDQQMD
EAVKAAFAEAKNTRRQVYSPLMYDDVGNGYITLQTPVYRDRDFLGTVAAVFSIEGILKRDIPPELSAKYKISIIDINNRE
LATTSTRPRLPRDAYYDLPLDPPGQGVSVRVYAYPQMTNFTNNTLVWLVAGLSCFVLWSLWSLWKHTRQRFEAQQALYAE
AFFRRAMENSVLIGMRVLDMHGRITHVNPAFCRMTGWDESDLVGKNAPFPYWPRDSYPEMQRQLDMTLRGKAPSSGFELR
VRRKDGSLFHARLYVSPLIDSSGRQTGWMSSMTDITEPKRAREELAAAHERFTTVLESLDAAVSVLAADEAELLFANRYY
RHLFGIRPDGHLELAGGGGFDSSAASSDSIDMVDAFAGLPATALTESTADAQEVYVQGIQKWFEVRRQYIQWVDGHLAQM
QIATDITTRKQAQELARQQDEKLQFTSRLMTMGEMASSLAHELNQPLAAINNYCSGTVALVKSGRTTPDNLLPVLEKTAQ
QAVRAGMIIKRIREFVKRSEPKRQATRVSDIVADAVGLAEIEARKRRIRIVTDMRSRLPVIYVDPVLIEQVLVNLLKNAA
EAMHDARPDAVDPVIRVVVKLDSGFVCISVVDQGPGVDEATAERLFEPFYSTKSDGMGMGLNICRSIIESHRGRLWVVNN
VESDGHITGATFHCSLPIGEPDGPSNGGSEAPTPQTVTGEL
>Mature_841_residues
MRAMLTDRLFARSARSAGPSADSSPSRWHHGPWWSNSYLLTPLLSILVFLVVMSLILWSLNRREQQQQEDTLYRNVAWAQ
QQIRLSMTGAQEQLQALARDLVSGRADPHSFQVSTADIMQGHPEILYMNWYTSAQQPRWPNNALPVLGQRLAKPNDQQMD
EAVKAAFAEAKNTRRQVYSPLMYDDVGNGYITLQTPVYRDRDFLGTVAAVFSIEGILKRDIPPELSAKYKISIIDINNRE
LATTSTRPRLPRDAYYDLPLDPPGQGVSVRVYAYPQMTNFTNNTLVWLVAGLSCFVLWSLWSLWKHTRQRFEAQQALYAE
AFFRRAMENSVLIGMRVLDMHGRITHVNPAFCRMTGWDESDLVGKNAPFPYWPRDSYPEMQRQLDMTLRGKAPSSGFELR
VRRKDGSLFHARLYVSPLIDSSGRQTGWMSSMTDITEPKRAREELAAAHERFTTVLESLDAAVSVLAADEAELLFANRYY
RHLFGIRPDGHLELAGGGGFDSSAASSDSIDMVDAFAGLPATALTESTADAQEVYVQGIQKWFEVRRQYIQWVDGHLAQM
QIATDITTRKQAQELARQQDEKLQFTSRLMTMGEMASSLAHELNQPLAAINNYCSGTVALVKSGRTTPDNLLPVLEKTAQ
QAVRAGMIIKRIREFVKRSEPKRQATRVSDIVADAVGLAEIEARKRRIRIVTDMRSRLPVIYVDPVLIEQVLVNLLKNAA
EAMHDARPDAVDPVIRVVVKLDSGFVCISVVDQGPGVDEATAERLFEPFYSTKSDGMGMGLNICRSIIESHRGRLWVVNN
VESDGHITGATFHCSLPIGEPDGPSNGGSEAPTPQTVTGEL

Specific function: Member of the two-component regulatory system dctS/dctR involved in the transport of C4-dicarboxylates. DctS functions as a membrane-associated protein kinase that phosphorylates dctR in response to environmental signals [H]

COG id: COG2202

COG function: function code T; FOG: PAS/PAC domain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=270, Percent_Identity=28.8888888888889, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1790436, Length=240, Percent_Identity=27.9166666666667, Blast_Score=97, Evalue=5e-21,
Organism=Escherichia coli, GI1790300, Length=232, Percent_Identity=27.5862068965517, Blast_Score=74, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 94233; Mature: 94233

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAMLTDRLFARSARSAGPSADSSPSRWHHGPWWSNSYLLTPLLSILVFLVVMSLILWSL
CCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
NRREQQQQEDTLYRNVAWAQQQIRLSMTGAQEQLQALARDLVSGRADPHSFQVSTADIMQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHC
GHPEILYMNWYTSAQQPRWPNNALPVLGQRLAKPNDQQMDEAVKAAFAEAKNTRRQVYSP
CCCCEEEEEEECCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
LMYDDVGNGYITLQTPVYRDRDFLGTVAAVFSIEGILKRDIPPELSAKYKISIIDINNRE
HHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCE
LATTSTRPRLPRDAYYDLPLDPPGQGVSVRVYAYPQMTNFTNNTLVWLVAGLSCFVLWSL
EEECCCCCCCCCCCEECCCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
WSLWKHTRQRFEAQQALYAEAFFRRAMENSVLIGMRVLDMHGRITHVNPAFCRMTGWDES
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCEEECCHHHEEECCCCCC
DLVGKNAPFPYWPRDSYPEMQRQLDMTLRGKAPSSGFELRVRRKDGSLFHARLYVSPLID
CCCCCCCCCCCCCCCCCHHHHHHHCCCEECCCCCCCCEEEEEECCCCEEEEEEEEEHHHC
SSGRQTGWMSSMTDITEPKRAREELAAAHERFTTVLESLDAAVSVLAADEAELLFANRYY
CCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
RHLFGIRPDGHLELAGGGGFDSSAASSDSIDMVDAFAGLPATALTESTADAQEVYVQGIQ
HHHHCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHH
KWFEVRRQYIQWVDGHLAQMQIATDITTRKQAQELARQQDEKLQFTSRLMTMGEMASSLA
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HELNQPLAAINNYCSGTVALVKSGRTTPDNLLPVLEKTAQQAVRAGMIIKRIREFVKRSE
HHHCCHHHHHHHHCCCHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PKRQATRVSDIVADAVGLAEIEARKRRIRIVTDMRSRLPVIYVDPVLIEQVLVNLLKNAA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHH
EAMHDARPDAVDPVIRVVVKLDSGFVCISVVDQGPGVDEATAERLFEPFYSTKSDGMGMG
HHHHCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCC
LNICRSIIESHRGRLWVVNNVESDGHITGATFHCSLPIGEPDGPSNGGSEAPTPQTVTGE
HHHHHHHHHHCCCCEEEEECCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCC
L
C
>Mature Secondary Structure
MRAMLTDRLFARSARSAGPSADSSPSRWHHGPWWSNSYLLTPLLSILVFLVVMSLILWSL
CCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
NRREQQQQEDTLYRNVAWAQQQIRLSMTGAQEQLQALARDLVSGRADPHSFQVSTADIMQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHC
GHPEILYMNWYTSAQQPRWPNNALPVLGQRLAKPNDQQMDEAVKAAFAEAKNTRRQVYSP
CCCCEEEEEEECCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
LMYDDVGNGYITLQTPVYRDRDFLGTVAAVFSIEGILKRDIPPELSAKYKISIIDINNRE
HHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCE
LATTSTRPRLPRDAYYDLPLDPPGQGVSVRVYAYPQMTNFTNNTLVWLVAGLSCFVLWSL
EEECCCCCCCCCCCEECCCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
WSLWKHTRQRFEAQQALYAEAFFRRAMENSVLIGMRVLDMHGRITHVNPAFCRMTGWDES
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCEEECCHHHEEECCCCCC
DLVGKNAPFPYWPRDSYPEMQRQLDMTLRGKAPSSGFELRVRRKDGSLFHARLYVSPLID
CCCCCCCCCCCCCCCCCHHHHHHHCCCEECCCCCCCCEEEEEECCCCEEEEEEEEEHHHC
SSGRQTGWMSSMTDITEPKRAREELAAAHERFTTVLESLDAAVSVLAADEAELLFANRYY
CCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
RHLFGIRPDGHLELAGGGGFDSSAASSDSIDMVDAFAGLPATALTESTADAQEVYVQGIQ
HHHHCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHH
KWFEVRRQYIQWVDGHLAQMQIATDITTRKQAQELARQQDEKLQFTSRLMTMGEMASSLA
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HELNQPLAAINNYCSGTVALVKSGRTTPDNLLPVLEKTAQQAVRAGMIIKRIREFVKRSE
HHHCCHHHHHHHHCCCHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PKRQATRVSDIVADAVGLAEIEARKRRIRIVTDMRSRLPVIYVDPVLIEQVLVNLLKNAA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHH
EAMHDARPDAVDPVIRVVVKLDSGFVCISVVDQGPGVDEATAERLFEPFYSTKSDGMGMG
HHHHCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCC
LNICRSIIESHRGRLWVVNNVESDGHITGATFHCSLPIGEPDGPSNGGSEAPTPQTVTGE
HHHHHHHHHHCCCCEEEEECCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCC
L
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8455557 [H]