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The map label for this gene is hscB

Identifier: 186476213

GI number: 186476213

Start: 1638249

End: 1638776

Strand: Reverse

Name: hscB

Synonym: Bphy_1455

Alternate gene names: 186476213

Gene position: 1638776-1638249 (Counterclockwise)

Preceding gene: 186476214

Following gene: 186476212

Centisome position: 47.1

GC content: 63.45

Gene sequence:

>528_bases
ATGGCCTCGCTCAACGACAGTCACTTCGCACTCTTCAACTTGCCCGAGCAGTTCGGACTGGACGTGTCCGCGCTCGATCG
CGCCTATCGCACGGTGCAGGCGCAGGTGCATCCGGACCGCTTTGCCGCGGCAGGCGACGCGCAAAAGCGCATCGCGATGC
AATGGGCGACCCGCACGAACGAGGCGTACCAGACGCTGCACGATCCATTGAAACGCGCGCGCTATCTGTTGTCGCTGCGC
GGCATCGACGTCGGCGCTGAAAACAACACAGCGATGGAACCGGCCTTCCTGATGCAGCAGATGGAATGGCGCGAGAGCAT
CGAGGATGCGTCGGCGGCGAAGAATGTGGACGCGCTCGACGCACTGTTGACCGATCTGCGCGACGAAGAGAAGGTGCGCT
TCACGAAGCTGGCCGCGCTGCTCGATAGCGGCTCGAATCAGGCCGCGAGCGAGGCGGTGCGGCAACTGATGTTCATCGAA
CGCGTGGCCGCGGAGATCGGCACGCAGATCGAGCGGCTAGACAACTAG

Upstream 100 bases:

>100_bases
AAAAGGCGGCCTGTGCCGCCTTTTTTCAATTTCGCCGCGTATTCAAACGCGCACATTTTCACGGCGTTGCGCTGCGCGCC
CTGGATGGACAAGTAAGCTG

Downstream 100 bases:

>100_bases
CGCCCGGCGCTGCCCGAAGCAGCGGCTCACATTCATCACGCGAACAACATGATCAGGACCGGGGCGAAACAGTCCCCGAA
GAAGACTCCAGATGGCTTTA

Product: co-chaperone HscB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 175; Mature: 174

Protein sequence:

>175_residues
MASLNDSHFALFNLPEQFGLDVSALDRAYRTVQAQVHPDRFAAAGDAQKRIAMQWATRTNEAYQTLHDPLKRARYLLSLR
GIDVGAENNTAMEPAFLMQQMEWRESIEDASAAKNVDALDALLTDLRDEEKVRFTKLAALLDSGSNQAASEAVRQLMFIE
RVAAEIGTQIERLDN

Sequences:

>Translated_175_residues
MASLNDSHFALFNLPEQFGLDVSALDRAYRTVQAQVHPDRFAAAGDAQKRIAMQWATRTNEAYQTLHDPLKRARYLLSLR
GIDVGAENNTAMEPAFLMQQMEWRESIEDASAAKNVDALDALLTDLRDEEKVRFTKLAALLDSGSNQAASEAVRQLMFIE
RVAAEIGTQIERLDN
>Mature_174_residues
ASLNDSHFALFNLPEQFGLDVSALDRAYRTVQAQVHPDRFAAAGDAQKRIAMQWATRTNEAYQTLHDPLKRARYLLSLRG
IDVGAENNTAMEPAFLMQQMEWRESIEDASAAKNVDALDALLTDLRDEEKVRFTKLAALLDSGSNQAASEAVRQLMFIER
VAAEIGTQIERLDN

Specific function: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward hscA

COG id: COG1076

COG function: function code O; DnaJ-domain-containing proteins 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain

Homologues:

Organism=Homo sapiens, GI50301234, Length=116, Percent_Identity=30.1724137931034, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI1788876, Length=155, Percent_Identity=36.7741935483871, Blast_Score=112, Evalue=1e-26,
Organism=Drosophila melanogaster, GI161084223, Length=161, Percent_Identity=32.2981366459627, Blast_Score=91, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HSCB_BURP8 (B2JIY6)

Other databases:

- EMBL:   CP001043
- RefSeq:   YP_001857683.1
- ProteinModelPortal:   B2JIY6
- SMR:   B2JIY6
- GeneID:   6242946
- GenomeReviews:   CP001043_GR
- KEGG:   bph:Bphy_1455
- HOGENOM:   HBG751004
- OMA:   AQRVAMQ
- ProtClustDB:   PRK03578
- HAMAP:   MF_00682
- InterPro:   IPR001623
- InterPro:   IPR009073
- InterPro:   IPR004640
- InterPro:   IPR015609
- Gene3D:   G3DSA:1.10.287.110
- Gene3D:   G3DSA:1.20.1280.20
- PANTHER:   PTHR11821
- SMART:   SM00271
- TIGRFAMs:   TIGR00714

Pfam domain/function: PF00226 DnaJ; PF07743 HSCB_C; SSF46565 DnaJ_N; SSF47144 HSC20_C

EC number: NA

Molecular weight: Translated: 19597; Mature: 19466

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS00636 DNAJ_1; PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASLNDSHFALFNLPEQFGLDVSALDRAYRTVQAQVHPDRFAAAGDAQKRIAMQWATRTN
CCCCCCCCEEEEECHHHHCCCHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHH
EAYQTLHDPLKRARYLLSLRGIDVGAENNTAMEPAFLMQQMEWRESIEDASAAKNVDALD
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHH
ALLTDLRDEEKVRFTKLAALLDSGSNQAASEAVRQLMFIERVAAEIGTQIERLDN
HHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ASLNDSHFALFNLPEQFGLDVSALDRAYRTVQAQVHPDRFAAAGDAQKRIAMQWATRTN
CCCCCCCEEEEECHHHHCCCHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHH
EAYQTLHDPLKRARYLLSLRGIDVGAENNTAMEPAFLMQQMEWRESIEDASAAKNVDALD
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHH
ALLTDLRDEEKVRFTKLAALLDSGSNQAASEAVRQLMFIERVAAEIGTQIERLDN
HHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA