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The map label for this gene is ldcA [H]

Identifier: 186476062

GI number: 186476062

Start: 1463094

End: 1464020

Strand: Reverse

Name: ldcA [H]

Synonym: Bphy_1304

Alternate gene names: 186476062

Gene position: 1464020-1463094 (Counterclockwise)

Preceding gene: 186476063

Following gene: 186476061

Centisome position: 42.08

GC content: 64.08

Gene sequence:

>927_bases
ATGGCCAGGCATCGCACCATCGAACTGATTGCGCCCTCGGGCTATCCGCACGATCCCAATGCGATTCATCTCGCGCTGAA
GCGTCTGCGTGCGCAAGGGCATCACGTGAAGAACGTCAGCGCGGCGCAGCGTCGCTATCAGCGTTTTGCCGGCACGGACG
GCGAGCGCGCAGCGGAATTGAACCGTTTGGGCGACCCGTCGCGGGAACTGCCCGATATCGTGCTTGCCGTGCGCGGCGGA
TACGGCGCAGTGCGCATCCTGCACGGTCTCGACTACCGCGGCCTGCAACGCCGCCTGCGCGATCAGCCCATCGCGTTCTG
CGGCCACAGCGATTTCACGGCGCTACAACTCGCGCTGCTGTCTCAGGCCGGCGTGACGACGTTTGGCGGCCCCATGCTCG
CAGGCGATTTCGGCGCGGAAAACGTCAGCGACTTCACCATGAAAAACTTCTGGCACGCGCTGACGTCCGAGACTTTCACG
ATTTCCAGCACGACGCCGCAGGCGCAGACCATCGATGTCACGGGCACGCTATGGGGCGGCAACCTGGCCGTGCTCGCGTC
GCTGGTCGGCTCGCCGTATATGCCGCCCGTGGAAGGCGGCATCCTGTTCGTCGAGGACGTGAACGAACAGCCGTTCCGCA
TCGAGCGGCTGATCTATCAGCTGCATCTGGCCGGCATCCTTGAACGCCAGCAGGCGCTCATGCTCGGCGACTTCTCGGGC
GGCAAGCCTTTCGACTACGATAACGGCTACGACTTGTGCGCCATGGTCGAGCAGGTGAGGTCGGTGATCGGCATTCCCAT
CGTGACCGGCCTGCAATTCGGGCACATTCCCGATATGGTGACGCTGCCCGTCGGCGGCGATGCTCGGCTCGTCGGGGGGG
CGCATGGATTCAAACTCACGGTCTCGGGCCATCCTGTGCTCGATTGA

Upstream 100 bases:

>100_bases
CGACGCGCCTCGCGTGAGGCACGCGCCGCGCTGAAAAATGAATCCGGCGCCGCCGATCCGCTGCAGGACGGCACGGCCGT
CAACTGACCGCTTACCGCAC

Downstream 100 bases:

>100_bases
CTGCGGCGTTTCATGTCGCGATGCATAGAGGCGAGGCCGGCTCGCCTTAATTTTCAAGTATTAAATGCAACTAACGGTCG
GTTGTTCAACAATGCCGACA

Product: L,D-carboxypeptidase A

Products: NA

Alternate protein names: LD-carboxypeptidase A; Muramoyltetrapeptide carboxypeptidase [H]

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MARHRTIELIAPSGYPHDPNAIHLALKRLRAQGHHVKNVSAAQRRYQRFAGTDGERAAELNRLGDPSRELPDIVLAVRGG
YGAVRILHGLDYRGLQRRLRDQPIAFCGHSDFTALQLALLSQAGVTTFGGPMLAGDFGAENVSDFTMKNFWHALTSETFT
ISSTTPQAQTIDVTGTLWGGNLAVLASLVGSPYMPPVEGGILFVEDVNEQPFRIERLIYQLHLAGILERQQALMLGDFSG
GKPFDYDNGYDLCAMVEQVRSVIGIPIVTGLQFGHIPDMVTLPVGGDARLVGGAHGFKLTVSGHPVLD

Sequences:

>Translated_308_residues
MARHRTIELIAPSGYPHDPNAIHLALKRLRAQGHHVKNVSAAQRRYQRFAGTDGERAAELNRLGDPSRELPDIVLAVRGG
YGAVRILHGLDYRGLQRRLRDQPIAFCGHSDFTALQLALLSQAGVTTFGGPMLAGDFGAENVSDFTMKNFWHALTSETFT
ISSTTPQAQTIDVTGTLWGGNLAVLASLVGSPYMPPVEGGILFVEDVNEQPFRIERLIYQLHLAGILERQQALMLGDFSG
GKPFDYDNGYDLCAMVEQVRSVIGIPIVTGLQFGHIPDMVTLPVGGDARLVGGAHGFKLTVSGHPVLD
>Mature_307_residues
ARHRTIELIAPSGYPHDPNAIHLALKRLRAQGHHVKNVSAAQRRYQRFAGTDGERAAELNRLGDPSRELPDIVLAVRGGY
GAVRILHGLDYRGLQRRLRDQPIAFCGHSDFTALQLALLSQAGVTTFGGPMLAGDFGAENVSDFTMKNFWHALTSETFTI
SSTTPQAQTIDVTGTLWGGNLAVLASLVGSPYMPPVEGGILFVEDVNEQPFRIERLIYQLHLAGILERQQALMLGDFSGG
KPFDYDNGYDLCAMVEQVRSVIGIPIVTGLQFGHIPDMVTLPVGGDARLVGGAHGFKLTVSGHPVLD

Specific function: Releases the terminal D-alanine residue from the cytoplasmic tetrapeptide recycling product L-Ala-gamma-D-Glu-meso- Dap-D-Ala. Can also cleave D-Ala from murein derivatives containing the tetrapeptide, i.e. MurNAc-tetrapeptide, UDP-MurNAc- tetrapeptide, G

COG id: COG1619

COG function: function code V; Uncharacterized proteins, homologs of microcin C7 resistance protein MccF

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S66 family [H]

Homologues:

Organism=Escherichia coli, GI1787441, Length=303, Percent_Identity=51.1551155115512, Blast_Score=297, Evalue=7e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003507 [H]

Pfam domain/function: PF02016 Peptidase_S66 [H]

EC number: NA

Molecular weight: Translated: 33418; Mature: 33286

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARHRTIELIAPSGYPHDPNAIHLALKRLRAQGHHVKNVSAAQRRYQRFAGTDGERAAEL
CCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHH
NRLGDPSRELPDIVLAVRGGYGAVRILHGLDYRGLQRRLRDQPIAFCGHSDFTALQLALL
HHCCCCCCCCCEEEEEEECCCCEEEHHHCCCHHHHHHHHHCCCEEEECCCCHHHHHHHHH
SQAGVTTFGGPMLAGDFGAENVSDFTMKNFWHALTSETFTISSTTPQAQTIDVTGTLWGG
HHCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCEEEEEEEEECCC
NLAVLASLVGSPYMPPVEGGILFVEDVNEQPFRIERLIYQLHLAGILERQQALMLGDFSG
HHHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEECCC
GKPFDYDNGYDLCAMVEQVRSVIGIPIVTGLQFGHIPDMVTLPVGGDARLVGGAHGFKLT
CCCCCCCCCCHHHHHHHHHHHHHCCHHHHCCCCCCCCCEEEEECCCCEEEEECCCCEEEE
VSGHPVLD
ECCCCCCC
>Mature Secondary Structure 
ARHRTIELIAPSGYPHDPNAIHLALKRLRAQGHHVKNVSAAQRRYQRFAGTDGERAAEL
CCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHH
NRLGDPSRELPDIVLAVRGGYGAVRILHGLDYRGLQRRLRDQPIAFCGHSDFTALQLALL
HHCCCCCCCCCEEEEEEECCCCEEEHHHCCCHHHHHHHHHCCCEEEECCCCHHHHHHHHH
SQAGVTTFGGPMLAGDFGAENVSDFTMKNFWHALTSETFTISSTTPQAQTIDVTGTLWGG
HHCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCEEEEEEEEECCC
NLAVLASLVGSPYMPPVEGGILFVEDVNEQPFRIERLIYQLHLAGILERQQALMLGDFSG
HHHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEECCC
GKPFDYDNGYDLCAMVEQVRSVIGIPIVTGLQFGHIPDMVTLPVGGDARLVGGAHGFKLT
CCCCCCCCCCHHHHHHHHHHHHHCCHHHHCCCCCCCCCEEEEECCCCEEEEECCCCEEEE
VSGHPVLD
ECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]