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The map label for this gene is tadA [H]

Identifier: 186476063

GI number: 186476063

Start: 1464034

End: 1464675

Strand: Reverse

Name: tadA [H]

Synonym: Bphy_1305

Alternate gene names: 186476063

Gene position: 1464675-1464034 (Counterclockwise)

Preceding gene: 186476064

Following gene: 186476062

Centisome position: 42.1

GC content: 67.29

Gene sequence:

>642_bases
GTGAGCATTGGCGTCGGTCCGGCCGGGCTGCCGTCCGCGGATTCTGTTTCGTCTGGCGACTTGTCTGCCGATACCGTCGG
GCCCTGCCTGACGACGGCCGCCGTCATTTTTTCCGAGCGCGATCGCCGTTTCATGGCGCTTGCGCAAGCCGCCGCGGAAG
AGGCGCGCGCCGCAGGCGAAGTGCCCGTCGGCGCGGTGCTGGTGCGCGGCGATGAAGTCATTGCGAAGGGTTTCAATCAT
CCCATCGGCGGTCACGATCCATCTGCGCATGCCGAAATGGCCGCACTGCGCGCCGCCGCGCTGACACTCGAGAACTACCG
GCTGCCGGGTTGCGAACTCTACGTGACACTGGAGCCGTGCCTGATGTGCGCGGGTGCGATCATGCACGCGCGCATCGCTC
GCGTGGTGTACGGCGCGCGCGATCCGAAGACGGGCGCGTGTGGCAGCGTCGTCGATGCGTTTGCCAACACGCAGCTGAAC
CATCATACGACCGTGACGGGGGGCGTGCTCGAAGAGGAGTGCGCGGCCGCTCTGCGCGCGTTTTTTGCAGACCGCCGACG
CGCCTCGCGTGAGGCACGCGCCGCGCTGAAAAATGAATCCGGCGCCGCCGATCCGCTGCAGGACGGCACGGCCGTCAACT
GA

Upstream 100 bases:

>100_bases
GCGGCGGGCCGCTGGTCATGCCGCGCGAATACTGCCGACGGATTGCGGAGCGCCTGTCGGAGCGCGCCGCCGACGAACCG
GCGCCAAACGCGGGGCCGGC

Downstream 100 bases:

>100_bases
CCGCTTACCGCACATGGCCAGGCATCGCACCATCGAACTGATTGCGCCCTCGGGCTATCCGCACGATCCCAATGCGATTC
ATCTCGCGCTGAAGCGTCTG

Product: zinc-binding CMP/dCMP deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 213; Mature: 212

Protein sequence:

>213_residues
MSIGVGPAGLPSADSVSSGDLSADTVGPCLTTAAVIFSERDRRFMALAQAAAEEARAAGEVPVGAVLVRGDEVIAKGFNH
PIGGHDPSAHAEMAALRAAALTLENYRLPGCELYVTLEPCLMCAGAIMHARIARVVYGARDPKTGACGSVVDAFANTQLN
HHTTVTGGVLEEECAAALRAFFADRRRASREARAALKNESGAADPLQDGTAVN

Sequences:

>Translated_213_residues
MSIGVGPAGLPSADSVSSGDLSADTVGPCLTTAAVIFSERDRRFMALAQAAAEEARAAGEVPVGAVLVRGDEVIAKGFNH
PIGGHDPSAHAEMAALRAAALTLENYRLPGCELYVTLEPCLMCAGAIMHARIARVVYGARDPKTGACGSVVDAFANTQLN
HHTTVTGGVLEEECAAALRAFFADRRRASREARAALKNESGAADPLQDGTAVN
>Mature_212_residues
SIGVGPAGLPSADSVSSGDLSADTVGPCLTTAAVIFSERDRRFMALAQAAAEEARAAGEVPVGAVLVRGDEVIAKGFNHP
IGGHDPSAHAEMAALRAAALTLENYRLPGCELYVTLEPCLMCAGAIMHARIARVVYGARDPKTGACGSVVDAFANTQLNH
HTTVTGGVLEEECAAALRAFFADRRRASREARAALKNESGAADPLQDGTAVN

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=129, Percent_Identity=36.4341085271318, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI19923945, Length=69, Percent_Identity=53.6231884057971, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI145693172, Length=157, Percent_Identity=52.8662420382166, Blast_Score=166, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI17541138, Length=153, Percent_Identity=33.9869281045752, Blast_Score=81, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17554608, Length=98, Percent_Identity=39.7959183673469, Blast_Score=80, Evalue=6e-16,
Organism=Drosophila melanogaster, GI21355527, Length=145, Percent_Identity=36.551724137931, Blast_Score=86, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 21970; Mature: 21839

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIGVGPAGLPSADSVSSGDLSADTVGPCLTTAAVIFSERDRRFMALAQAAAEEARAAGE
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCC
VPVGAVLVRGDEVIAKGFNHPIGGHDPSAHAEMAALRAAALTLENYRLPGCELYVTLEPC
CCCCEEEEECCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHH
LMCAGAIMHARIARVVYGARDPKTGACGSVVDAFANTQLNHHTTVTGGVLEEECAAALRA
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHH
FFADRRRASREARAALKNESGAADPLQDGTAVN
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SIGVGPAGLPSADSVSSGDLSADTVGPCLTTAAVIFSERDRRFMALAQAAAEEARAAGE
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCC
VPVGAVLVRGDEVIAKGFNHPIGGHDPSAHAEMAALRAAALTLENYRLPGCELYVTLEPC
CCCCEEEEECCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHH
LMCAGAIMHARIARVVYGARDPKTGACGSVVDAFANTQLNHHTTVTGGVLEEECAAALRA
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHH
FFADRRRASREARAALKNESGAADPLQDGTAVN
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]