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The map label for this gene is ynfJ [C]

Identifier: 186476017

GI number: 186476017

Start: 1408632

End: 1410365

Strand: Direct

Name: ynfJ [C]

Synonym: Bphy_1258

Alternate gene names: 186476017

Gene position: 1408632-1410365 (Clockwise)

Preceding gene: 186476016

Following gene: 186476018

Centisome position: 40.49

GC content: 65.11

Gene sequence:

>1734_bases
GTGCTTTCATTTCTGCTGAGACTGCGCACCCGCGCCGCCCATCTCTTCCGCCTGTCCGATGCGCACACGATGCTGGTTTG
GTCGGTGATCGTCGGGATCGCGGGCGCCTTCGCGACCATTGCCTTTCGCGAAGGCATCTCGCTGCTGCAGCGCGTATTCA
CCGGGCAGGACGGCAGTCTCGTTGAAATGGCGCGGCGACTGCCGCTCGCGATGCGCATCGGTTTGCCCGCATTCGGCGGC
CTGATCGCGGGCATGCTGCTGCTCCTCGCGCAACGCGGCGTCGACAGGAAGCTGCACACGGATTACATGGAAGCCGTCGT
GATCGGCGATGGCGTCGTGCCAGTGCGCGTCAGTCTGTGGCGCAGCGCGTCGTCGCTGTTCACCATTTCGAGCGGCGGTT
CGATCGGCCGCGAAGGTCCGATGGTGCAACTCGCGGCGCTCGGCGCGTCGCTGATCGGACGCGTCGTGCATTTCGATCCG
CCGCGTCTCAGGCTGCTTGTCGCGTGCGGCGCGGCGGCGGGCATCACGTCCGCATACAGCGCGCCCATCGCGGGCGCTTT
TTTCGTCACCGAAATCGTGCTTGGTTCGATCGCAATGGAAAGCTTCGGGCCCGTCGTGGTGTCCTCGGTGGTGTCGAACA
TCGTGATGCGCGAATTCGCCGGGTACAAGCCGCCGTACGAGATGCCCGTGTTTCCGCCCGTCGCCGGACTCGAAGTGCTG
CTCTTTGTCGCGCTCGGCCTGCTGTGCGGCGCGGCGGCGCCGCAGTTTCTGCGGCTCATCGACGCCAGCAAGTCGGCATT
CGGCCGTCTGCCCGTGCCCTTGCCTTTTCGGCTCGCGCTCGGCGGACTGGTCGTCGGCATTCTGTCCGTCTGGACACCCG
AGGTGTGGGGCAACGGCTATAGCGTCGTCAACTCGATCCTGCATTCGCCGTGGACATGGACGGCACTGCTTGTCGTGCTC
GCTTTCAAGCTGATCGCGACGGCGGCCACCGTGGGTTCGGGCGCAGTCGGCGGTGTGTTCACGCCGACGCTCTTCGTCGG
CGCCGTGATCGGCTCGCTGTTCGGCCTCGGCATGAATGGGCTGTGGCCGCATGCGACGTCCGCGCCGTTCGCCTACGCGA
TGGTCGGCATGGGCGCGTTTCTCGCGGGCGCGACGCAGGCGCCGCTGATGGCGATCCTGATGATCTTCGAAATGACGCTG
AGCTATCAGGTGGTGCTGCCGCTCATGCTGTCGTGCGTGGTCGCCTACTTCGCAGCGCGTGCGATCGGCAAGACCTCCAT
GTACGACATCACGCTGCACCGCAATCGCGAGGAACAGGAACGCATGCGGCTGCGCGCGACGCAGATGCGCGAACTGATCC
GCCCGCCGCAAACCGTCGTGCAGCCGAACGCGACCGTGCACGACATGACGCGCGTGTTCCTCGAATACCCCGTCAAATAT
CTGTACGTGACGGATGAGAGCGATGCGTTTCTCGGCGTGGTTGCGCTGAAGGACATCACGTCCGATCTGCTCGACAGACG
CGACACCTCGACCAAGACGGCCGCCGATTATCTGCAGCCGCATTTCGACGTGCTGACGCCGGACATGCCGCTCGGCGTCG
CGCTTCAGCATTTCATGGCATTCCAGGGCGAACGGCTACCCGTCGTCGAAAGCAGGGCGCGGCCGACGCTCGCGGGCGTC
GTCTACAAAACCTCGTTGCTCGACGCATACTTCCGGATGAACCCGGCGCGGTAG

Upstream 100 bases:

>100_bases
ACCCGAAGGGACGCGCCGCCTTTCAAACCGCCGCCGCGCGAGGCCGATACCATGCAGGCCGCACGTGTCCAATCAACCAC
CCTAAACGCCCGCTCCCGCC

Downstream 100 bases:

>100_bases
TCCGCCAACCTCGGTGCGTTGCCGTTCGCGCGCCTGGCAAAGCGCGGCAAGTTCCCTACAATGAATTGACCCGGCGCCGG
GCACGGCCCCGGGCACGAAA

Product: putative voltage-gated ClC-type chloride channel ClcB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 577; Mature: 577

Protein sequence:

>577_residues
MLSFLLRLRTRAAHLFRLSDAHTMLVWSVIVGIAGAFATIAFREGISLLQRVFTGQDGSLVEMARRLPLAMRIGLPAFGG
LIAGMLLLLAQRGVDRKLHTDYMEAVVIGDGVVPVRVSLWRSASSLFTISSGGSIGREGPMVQLAALGASLIGRVVHFDP
PRLRLLVACGAAAGITSAYSAPIAGAFFVTEIVLGSIAMESFGPVVVSSVVSNIVMREFAGYKPPYEMPVFPPVAGLEVL
LFVALGLLCGAAAPQFLRLIDASKSAFGRLPVPLPFRLALGGLVVGILSVWTPEVWGNGYSVVNSILHSPWTWTALLVVL
AFKLIATAATVGSGAVGGVFTPTLFVGAVIGSLFGLGMNGLWPHATSAPFAYAMVGMGAFLAGATQAPLMAILMIFEMTL
SYQVVLPLMLSCVVAYFAARAIGKTSMYDITLHRNREEQERMRLRATQMRELIRPPQTVVQPNATVHDMTRVFLEYPVKY
LYVTDESDAFLGVVALKDITSDLLDRRDTSTKTAADYLQPHFDVLTPDMPLGVALQHFMAFQGERLPVVESRARPTLAGV
VYKTSLLDAYFRMNPAR

Sequences:

>Translated_577_residues
MLSFLLRLRTRAAHLFRLSDAHTMLVWSVIVGIAGAFATIAFREGISLLQRVFTGQDGSLVEMARRLPLAMRIGLPAFGG
LIAGMLLLLAQRGVDRKLHTDYMEAVVIGDGVVPVRVSLWRSASSLFTISSGGSIGREGPMVQLAALGASLIGRVVHFDP
PRLRLLVACGAAAGITSAYSAPIAGAFFVTEIVLGSIAMESFGPVVVSSVVSNIVMREFAGYKPPYEMPVFPPVAGLEVL
LFVALGLLCGAAAPQFLRLIDASKSAFGRLPVPLPFRLALGGLVVGILSVWTPEVWGNGYSVVNSILHSPWTWTALLVVL
AFKLIATAATVGSGAVGGVFTPTLFVGAVIGSLFGLGMNGLWPHATSAPFAYAMVGMGAFLAGATQAPLMAILMIFEMTL
SYQVVLPLMLSCVVAYFAARAIGKTSMYDITLHRNREEQERMRLRATQMRELIRPPQTVVQPNATVHDMTRVFLEYPVKY
LYVTDESDAFLGVVALKDITSDLLDRRDTSTKTAADYLQPHFDVLTPDMPLGVALQHFMAFQGERLPVVESRARPTLAGV
VYKTSLLDAYFRMNPAR
>Mature_577_residues
MLSFLLRLRTRAAHLFRLSDAHTMLVWSVIVGIAGAFATIAFREGISLLQRVFTGQDGSLVEMARRLPLAMRIGLPAFGG
LIAGMLLLLAQRGVDRKLHTDYMEAVVIGDGVVPVRVSLWRSASSLFTISSGGSIGREGPMVQLAALGASLIGRVVHFDP
PRLRLLVACGAAAGITSAYSAPIAGAFFVTEIVLGSIAMESFGPVVVSSVVSNIVMREFAGYKPPYEMPVFPPVAGLEVL
LFVALGLLCGAAAPQFLRLIDASKSAFGRLPVPLPFRLALGGLVVGILSVWTPEVWGNGYSVVNSILHSPWTWTALLVVL
AFKLIATAATVGSGAVGGVFTPTLFVGAVIGSLFGLGMNGLWPHATSAPFAYAMVGMGAFLAGATQAPLMAILMIFEMTL
SYQVVLPLMLSCVVAYFAARAIGKTSMYDITLHRNREEQERMRLRATQMRELIRPPQTVVQPNATVHDMTRVFLEYPVKY
LYVTDESDAFLGVVALKDITSDLLDRRDTSTKTAADYLQPHFDVLTPDMPLGVALQHFMAFQGERLPVVESRARPTLAGV
VYKTSLLDAYFRMNPAR

Specific function: Unknown

COG id: COG0038

COG function: function code P; Chloride channel protein EriC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chloride channel (TC 2.A.49) family. ClcB subfamily [H]

Homologues:

Organism=Homo sapiens, GI55770838, Length=455, Percent_Identity=23.2967032967033, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI55770840, Length=455, Percent_Identity=23.2967032967033, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI189217923, Length=478, Percent_Identity=22.8033472803347, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI189217921, Length=478, Percent_Identity=22.8033472803347, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI4557473, Length=478, Percent_Identity=22.8033472803347, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI153252026, Length=493, Percent_Identity=23.5294117647059, Blast_Score=80, Evalue=7e-15,
Organism=Escherichia coli, GI87081943, Length=420, Percent_Identity=41.9047619047619, Blast_Score=219, Evalue=3e-58,
Organism=Escherichia coli, GI1786350, Length=325, Percent_Identity=28.9230769230769, Blast_Score=96, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI17532615, Length=497, Percent_Identity=21.5291750503018, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24665008, Length=450, Percent_Identity=23.7777777777778, Blast_Score=86, Evalue=9e-17,
Organism=Drosophila melanogaster, GI45551566, Length=436, Percent_Identity=23.1651376146789, Blast_Score=73, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014743
- InterPro:   IPR001807 [H]

Pfam domain/function: PF00654 Voltage_CLC [H]

EC number: NA

Molecular weight: Translated: 62177; Mature: 62177

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSFLLRLRTRAAHLFRLSDAHTMLVWSVIVGIAGAFATIAFREGISLLQRVFTGQDGSL
CHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
VEMARRLPLAMRIGLPAFGGLIAGMLLLLAQRGVDRKLHTDYMEAVVIGDGVVPVRVSLW
HHHHHHCCHHEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHH
RSASSLFTISSGGSIGREGPMVQLAALGASLIGRVVHFDPPRLRLLVACGAAAGITSAYS
HCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHEEEEECCCHHHHHHHHC
APIAGAFFVTEIVLGSIAMESFGPVVVSSVVSNIVMREFAGYKPPYEMPVFPPVAGLEVL
CCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHH
LFVALGLLCGAAAPQFLRLIDASKSAFGRLPVPLPFRLALGGLVVGILSVWTPEVWGNGY
HHHHHHHHHHCCHHHHHHHHHHCHHHCCCCCCCCHHHHHHHHHHHHHHHHHCHHHCCCCH
SVVNSILHSPWTWTALLVVLAFKLIATAATVGSGAVGGVFTPTLFVGAVIGSLFGLGMNG
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCC
LWPHATSAPFAYAMVGMGAFLAGATQAPLMAILMIFEMTLSYQVVLPLMLSCVVAYFAAR
CCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIGKTSMYDITLHRNREEQERMRLRATQMRELIRPPQTVVQPNATVHDMTRVFLEYPVKY
HHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHCCEEE
LYVTDESDAFLGVVALKDITSDLLDRRDTSTKTAADYLQPHFDVLTPDMPLGVALQHFMA
EEEECCCCCEEHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHCCCCCCHHHHHHHHHH
FQGERLPVVESRARPTLAGVVYKTSLLDAYFRMNPAR
HCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLSFLLRLRTRAAHLFRLSDAHTMLVWSVIVGIAGAFATIAFREGISLLQRVFTGQDGSL
CHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
VEMARRLPLAMRIGLPAFGGLIAGMLLLLAQRGVDRKLHTDYMEAVVIGDGVVPVRVSLW
HHHHHHCCHHEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHH
RSASSLFTISSGGSIGREGPMVQLAALGASLIGRVVHFDPPRLRLLVACGAAAGITSAYS
HCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHEEEEECCCHHHHHHHHC
APIAGAFFVTEIVLGSIAMESFGPVVVSSVVSNIVMREFAGYKPPYEMPVFPPVAGLEVL
CCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHH
LFVALGLLCGAAAPQFLRLIDASKSAFGRLPVPLPFRLALGGLVVGILSVWTPEVWGNGY
HHHHHHHHHHCCHHHHHHHHHHCHHHCCCCCCCCHHHHHHHHHHHHHHHHHCHHHCCCCH
SVVNSILHSPWTWTALLVVLAFKLIATAATVGSGAVGGVFTPTLFVGAVIGSLFGLGMNG
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCC
LWPHATSAPFAYAMVGMGAFLAGATQAPLMAILMIFEMTLSYQVVLPLMLSCVVAYFAAR
CCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIGKTSMYDITLHRNREEQERMRLRATQMRELIRPPQTVVQPNATVHDMTRVFLEYPVKY
HHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHCCEEE
LYVTDESDAFLGVVALKDITSDLLDRRDTSTKTAADYLQPHFDVLTPDMPLGVALQHFMA
EEEECCCCCEEHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHCCCCCCHHHHHHHHHH
FQGERLPVVESRARPTLAGVVYKTSLLDAYFRMNPAR
HCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]