Click here to switch to the map view.

The map label for this gene is ompR [H]

Identifier: 186475955

GI number: 186475955

Start: 1337117

End: 1337863

Strand: Reverse

Name: ompR [H]

Synonym: Bphy_1190

Alternate gene names: 186475955

Gene position: 1337863-1337117 (Counterclockwise)

Preceding gene: 186475956

Following gene: 186475954

Centisome position: 38.45

GC content: 66.67

Gene sequence:

>747_bases
GTGGATAAAACGGATCACGTTCTGATCGTCGACGACGACCGCGACATTCGTGAGCTGGTCGGCACATACCTCACCCGCAA
CGGCGTGCGCGCGACGCTCGCGTCGGGTGGCCGGCAGATGCGCGCGGCGCTCGCTGCCGAGCGGCCCGATCTGATCGTGC
TCGATCTCATGTTGCCGGGCGAGAGCGGCCTTGACCTGTGCCGGGAGCTGCGCGCGGGCGAATTCCAGACCGTGCCGATC
CTGATGCTGACGGCGCTGAGCGAGGAGACCGATCGCGTCGTCGGACTGGAAATGGGCGCCGACGATTACCTCGCAAAGCC
CTTCGCGGTGCGCGAACTGCTCGCGCGCATCCGCGCCATTTTGCGCCGCTCGCGCATGATGCCGCCCGGCAACAGCAGCG
AGCAGCCGGCCTCCGCTCACTTCCTGCGTTTCGGCGACTGGCGCCTCGATACGATCGGCCGCAACCTGATCGACGGCGAC
GGCACGCTGGTCGCGCTGAGCGGCGCCGAGTACCGCCTGCTGCGTGTGTTTGTCGATCATCCGCAGCGCGTGCTGACGCG
CGACCAGTTGTTGACGCTCACGCAAGGCCGGCAGACAGAGCCATTCGACCGTTCGATCGATCTGCTCGTGAGCCGTGTGC
GCCAGCGCCTCGGCGACGACGCACGGGAGCCGCGCTACATCAAGACGCTGCGCAACGAGGGCTATGTATTCTCGTCGCTC
GTGACAGCCGAGGAAAACGGCGGATGA

Upstream 100 bases:

>100_bases
ACCCGTATGCGCTCGAGGCGTCGGTGGCGGACGGCAAGAGCCTGTCCGTGGTCGATGACGCGTAAGATAAGCGAACCCCC
GGCAGCCGAAGGAGCCTTGT

Downstream 100 bases:

>100_bases
GCACGCCAACGGTTCATATGCAGGATCGCATGACGGGCCTTTTACGCGGCCTGTGGCGACCGCGCACGCTGTTCGTGCGG
CTGTCGCTGATCTTCGTCGC

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MDKTDHVLIVDDDRDIRELVGTYLTRNGVRATLASGGRQMRAALAAERPDLIVLDLMLPGESGLDLCRELRAGEFQTVPI
LMLTALSEETDRVVGLEMGADDYLAKPFAVRELLARIRAILRRSRMMPPGNSSEQPASAHFLRFGDWRLDTIGRNLIDGD
GTLVALSGAEYRLLRVFVDHPQRVLTRDQLLTLTQGRQTEPFDRSIDLLVSRVRQRLGDDAREPRYIKTLRNEGYVFSSL
VTAEENGG

Sequences:

>Translated_248_residues
MDKTDHVLIVDDDRDIRELVGTYLTRNGVRATLASGGRQMRAALAAERPDLIVLDLMLPGESGLDLCRELRAGEFQTVPI
LMLTALSEETDRVVGLEMGADDYLAKPFAVRELLARIRAILRRSRMMPPGNSSEQPASAHFLRFGDWRLDTIGRNLIDGD
GTLVALSGAEYRLLRVFVDHPQRVLTRDQLLTLTQGRQTEPFDRSIDLLVSRVRQRLGDDAREPRYIKTLRNEGYVFSSL
VTAEENGG
>Mature_248_residues
MDKTDHVLIVDDDRDIRELVGTYLTRNGVRATLASGGRQMRAALAAERPDLIVLDLMLPGESGLDLCRELRAGEFQTVPI
LMLTALSEETDRVVGLEMGADDYLAKPFAVRELLARIRAILRRSRMMPPGNSSEQPASAHFLRFGDWRLDTIGRNLIDGD
GTLVALSGAEYRLLRVFVDHPQRVLTRDQLLTLTQGRQTEPFDRSIDLLVSRVRQRLGDDAREPRYIKTLRNEGYVFSSL
VTAEENGG

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=237, Percent_Identity=44.3037974683544, Blast_Score=190, Evalue=7e-50,
Organism=Escherichia coli, GI1790863, Length=236, Percent_Identity=36.4406779661017, Blast_Score=154, Evalue=4e-39,
Organism=Escherichia coli, GI1786599, Length=234, Percent_Identity=37.1794871794872, Blast_Score=144, Evalue=4e-36,
Organism=Escherichia coli, GI145693140, Length=234, Percent_Identity=34.6153846153846, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1788394, Length=243, Percent_Identity=36.6255144032922, Blast_Score=141, Evalue=4e-35,
Organism=Escherichia coli, GI1787229, Length=235, Percent_Identity=34.468085106383, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI2367329, Length=235, Percent_Identity=37.8723404255319, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI1786911, Length=232, Percent_Identity=35.7758620689655, Blast_Score=127, Evalue=6e-31,
Organism=Escherichia coli, GI1786784, Length=231, Percent_Identity=35.9307359307359, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1790860, Length=234, Percent_Identity=33.7606837606838, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI1789402, Length=231, Percent_Identity=33.3333333333333, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1790552, Length=240, Percent_Identity=33.75, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI87082012, Length=234, Percent_Identity=30.3418803418803, Blast_Score=97, Evalue=8e-22,
Organism=Escherichia coli, GI1787375, Length=232, Percent_Identity=28.448275862069, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788550, Length=113, Percent_Identity=32.7433628318584, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1790299, Length=126, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27818; Mature: 27818

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKTDHVLIVDDDRDIRELVGTYLTRNGVRATLASGGRQMRAALAAERPDLIVLDLMLPG
CCCCCEEEEEECCHHHHHHHHHHHHCCCCEEHHHCCCHHHHHHHHCCCCCEEEEEEEECC
ESGLDLCRELRAGEFQTVPILMLTALSEETDRVVGLEMGADDYLAKPFAVRELLARIRAI
CCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCEEEEEECCCHHHCCHHHHHHHHHHHHHH
LRRSRMMPPGNSSEQPASAHFLRFGDWRLDTIGRNLIDGDGTLVALSGAEYRLLRVFVDH
HHHHCCCCCCCCCCCCCHHHEEEECCEEHHHHCCCEECCCCCEEEECCCCEEEHHHHHHC
PQRVLTRDQLLTLTQGRQTEPFDRSIDLLVSRVRQRLGDDAREPRYIKTLRNEGYVFSSL
CHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCEEEEHE
VTAEENGG
EECCCCCC
>Mature Secondary Structure
MDKTDHVLIVDDDRDIRELVGTYLTRNGVRATLASGGRQMRAALAAERPDLIVLDLMLPG
CCCCCEEEEEECCHHHHHHHHHHHHCCCCEEHHHCCCHHHHHHHHCCCCCEEEEEEEECC
ESGLDLCRELRAGEFQTVPILMLTALSEETDRVVGLEMGADDYLAKPFAVRELLARIRAI
CCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCEEEEEECCCHHHCCHHHHHHHHHHHHHH
LRRSRMMPPGNSSEQPASAHFLRFGDWRLDTIGRNLIDGDGTLVALSGAEYRLLRVFVDH
HHHHCCCCCCCCCCCCCHHHEEEECCEEHHHHCCCEECCCCCEEEECCCCEEEHHHHHHC
PQRVLTRDQLLTLTQGRQTEPFDRSIDLLVSRVRQRLGDDAREPRYIKTLRNEGYVFSSL
CHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCEEEEHE
VTAEENGG
EECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]