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The map label for this gene is arcD [H]

Identifier: 186475854

GI number: 186475854

Start: 1228794

End: 1230275

Strand: Direct

Name: arcD [H]

Synonym: Bphy_1089

Alternate gene names: 186475854

Gene position: 1228794-1230275 (Clockwise)

Preceding gene: 186475853

Following gene: 186475855

Centisome position: 35.32

GC content: 59.45

Gene sequence:

>1482_bases
ATGTCTGATTCAGTGTCTCAACCCGCATCCGGCTCGAAGGTGAGTCCGTCTAGTGCATCCGCGGCCGCTCCCAGGCTGCA
TCTCGGCGCACTGACAGCGCTGGTGGTGGGCTCCATGATCGGAGGCGGCATCTTCTCGTTGCCGCAGAACATGGCTGTCA
GCGCCGGCGCGGGCGCGGTGCTGATCGGATGGGCAATTACTGCCGTGGGCATGCTGACACTGGCCTTCGTGTTCCAGACG
CTCGCGAATCGCAAGCCCGAACTCGATGGCGGCGTGTATATCTACGCGAAGCAAGGGTTCGGCGACTATATGGGCTTCTC
GTCGGCGTGGGGCTACTGGATCAGCGCATGGCTCGGGAACGTCGGCTACTTCGTCCTGCTGTTCGGCACCTTCGGCTACT
TCTTTCCGGTTTTCGGCGAAGGCAATACGCCCGTCGCGATCGCCTGCGCCTCGGTGTTGCTGTGGGGCGTTCATTTCCTC
GTGCTGCAGGGCATCAAGGAAGCCGCGTTCGTGAACATGGTGACGACAATCGCCAAGGTCGTGCCAATCGTTTTATTCAT
CGTGATCTGCGCATTTGCGTTCAACGCACACTTTTTCGCGAACGACTTTTTCGGCCTGAACACGCCAAAACTCGGGAGCG
TAGCGAATCAGGTGCGAGGCACGATGCTCGTGACAGTCTGGGTTTTTATCGGCATCGAAGGCGCCAGCATTTTCTCTGCA
CGCGCAGAAAAACGGACGGACGTCGGCAAGGCGACGATCATGGGGTTCATTGGCGTACTGCTCGTTCTCGTACTCGTCAA
CGTGCTGTCGCTCGGGATCATGGCGCGACCTGATCTTGCCGCGCTGCAGAACCCGTCGATGGCTGGGGTGCTCGAGCATG
TCGTGGGTCACTGGGGTGCAATTCTGATCAGTGTCGGCCTCGTCATTTCGCTGCTGGGCGCCCTGCTCTCGTGGGTTCTG
CTTTGCGCCGAGATCATCTTTTCGGCTGCAAGGGACAACACGATGCCGAGCTTCGTGCGCAAGGAAAATGCGAAGAAGGT
TCCAGCGAATGCGCTGTGGCTTACCAACGGCCTGACGCAGGCATTCCTGCTCATCACGCTTTTCTCCAAAGGGACCTACC
TCTCGCTGATCTATCTGGCAACTTCAATGATCCTGTTGCCCTACTTCTGGTCCGCGGCTTATGCGTTGCGCGTCGCATGG
CGCCGCGAAACGTATGAGCAGGAGCCCGCCCAACGCAACAAGGACCTGGTGGTGGCAACCATCGCGGTGATCTATGCCGT
GTGGCTGCTCTACGCGGGTGGACTCAAGTATGTGTTGTTGTCGGCGCTTTTATATGCCCCCGGCGCCGTGCTGTTTGCCA
AGGCGAAGCGCGAAACCGGGCAACCCGTGTTCACGCTGATGGAAAAGCTGGTCTTCGCCGCGGTCGTGGCAGGAGCACTG
GTGGCGGCATTCGGCCTTTACAAGGGCTTCCTCACGCTCTGA

Upstream 100 bases:

>100_bases
GGCACGCGTCCTGATCCGCAGCGCTTGCTTATCGACTGTTCAATTCATTGAACGGCACGCTTCCTCGCCACGGATTCCAA
ACAGCTGAAGGAGAGGTTAC

Downstream 100 bases:

>100_bases
TGACAGGAGACACATGATGACCACGGAAACAATGAAGTATGGCGTTCATTCGGAGGCGGGCAAGCTTCGCAAGGTGATGG
TCTGCTCGCCGGGCCTCGCG

Product: arginine/ornithine antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 493; Mature: 492

Protein sequence:

>493_residues
MSDSVSQPASGSKVSPSSASAAAPRLHLGALTALVVGSMIGGGIFSLPQNMAVSAGAGAVLIGWAITAVGMLTLAFVFQT
LANRKPELDGGVYIYAKQGFGDYMGFSSAWGYWISAWLGNVGYFVLLFGTFGYFFPVFGEGNTPVAIACASVLLWGVHFL
VLQGIKEAAFVNMVTTIAKVVPIVLFIVICAFAFNAHFFANDFFGLNTPKLGSVANQVRGTMLVTVWVFIGIEGASIFSA
RAEKRTDVGKATIMGFIGVLLVLVLVNVLSLGIMARPDLAALQNPSMAGVLEHVVGHWGAILISVGLVISLLGALLSWVL
LCAEIIFSAARDNTMPSFVRKENAKKVPANALWLTNGLTQAFLLITLFSKGTYLSLIYLATSMILLPYFWSAAYALRVAW
RRETYEQEPAQRNKDLVVATIAVIYAVWLLYAGGLKYVLLSALLYAPGAVLFAKAKRETGQPVFTLMEKLVFAAVVAGAL
VAAFGLYKGFLTL

Sequences:

>Translated_493_residues
MSDSVSQPASGSKVSPSSASAAAPRLHLGALTALVVGSMIGGGIFSLPQNMAVSAGAGAVLIGWAITAVGMLTLAFVFQT
LANRKPELDGGVYIYAKQGFGDYMGFSSAWGYWISAWLGNVGYFVLLFGTFGYFFPVFGEGNTPVAIACASVLLWGVHFL
VLQGIKEAAFVNMVTTIAKVVPIVLFIVICAFAFNAHFFANDFFGLNTPKLGSVANQVRGTMLVTVWVFIGIEGASIFSA
RAEKRTDVGKATIMGFIGVLLVLVLVNVLSLGIMARPDLAALQNPSMAGVLEHVVGHWGAILISVGLVISLLGALLSWVL
LCAEIIFSAARDNTMPSFVRKENAKKVPANALWLTNGLTQAFLLITLFSKGTYLSLIYLATSMILLPYFWSAAYALRVAW
RRETYEQEPAQRNKDLVVATIAVIYAVWLLYAGGLKYVLLSALLYAPGAVLFAKAKRETGQPVFTLMEKLVFAAVVAGAL
VAAFGLYKGFLTL
>Mature_492_residues
SDSVSQPASGSKVSPSSASAAAPRLHLGALTALVVGSMIGGGIFSLPQNMAVSAGAGAVLIGWAITAVGMLTLAFVFQTL
ANRKPELDGGVYIYAKQGFGDYMGFSSAWGYWISAWLGNVGYFVLLFGTFGYFFPVFGEGNTPVAIACASVLLWGVHFLV
LQGIKEAAFVNMVTTIAKVVPIVLFIVICAFAFNAHFFANDFFGLNTPKLGSVANQVRGTMLVTVWVFIGIEGASIFSAR
AEKRTDVGKATIMGFIGVLLVLVLVNVLSLGIMARPDLAALQNPSMAGVLEHVVGHWGAILISVGLVISLLGALLSWVLL
CAEIIFSAARDNTMPSFVRKENAKKVPANALWLTNGLTQAFLLITLFSKGTYLSLIYLATSMILLPYFWSAAYALRVAWR
RETYEQEPAQRNKDLVVATIAVIYAVWLLYAGGLKYVLLSALLYAPGAVLFAKAKRETGQPVFTLMEKLVFAAVVAGALV
AAFGLYKGFLTL

Specific function: Catalyzes an electroneutral exchange between arginine and ornithine to allow high-efficiency energy conversion in the arginine deiminase pathway [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI1787890, Length=439, Percent_Identity=46.2414578587699, Blast_Score=379, Evalue=1e-106,
Organism=Escherichia coli, GI2367353, Length=427, Percent_Identity=28.5714285714286, Blast_Score=138, Evalue=9e-34,
Organism=Escherichia coli, GI1790575, Length=389, Percent_Identity=28.0205655526992, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1786908, Length=459, Percent_Identity=22.8758169934641, Blast_Score=88, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004754
- InterPro:   IPR022461 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 52592; Mature: 52461

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHCC
>Mature Secondary Structure 
SDSVSQPASGSKVSPSSASAAAPRLHLGALTALVVGSMIGGGIFSLPQNMAVSAGAGAV
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHCCCCCEECCCCCHH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HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2158926; 10984043; 1311296 [H]