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The map label for this gene is udg [H]

Identifier: 186475823

GI number: 186475823

Start: 1188289

End: 1189719

Strand: Direct

Name: udg [H]

Synonym: Bphy_1058

Alternate gene names: 186475823

Gene position: 1188289-1189719 (Clockwise)

Preceding gene: 186475822

Following gene: 186475824

Centisome position: 34.15

GC content: 65.69

Gene sequence:

>1431_bases
ATGAACCTGACGATCGTGGGAACCGGATACGTGGGCCTCGTGACGGGCGCCTGTCTGGCCGACATCGGTCACGACGTATT
CTGCCTCGACGTCGATCAGCGCAAGATCGACGTGCTGAATAACGGCGGCGTGCCGATTCATGAGCCGGGTCTGCTGGAAA
TCATCGCGCGCAACCGCAAGGCGGGGCGCCTGACGTTTTCGACGAATATCGAAGCGGCCGTCGCGCATGGCGACATCCAG
TTCATCGCCGTCGGCACGCCACCCGACGAGGACGGCTCGGCCGACCTGCAATACGTGCTGGCCGCCGCGCGCAACATCGG
CCGTCACATGAACGGCTTCAAGGTGATCGTCGACAAGTCGACGGTGCCCGTCGGCACCGCGCGCCGCGTCGCGCATGCCG
TGCAGGACGAGCTCGACCAGCGCGGCCTGCAGCAGATGTTCTCGGTCGTGTCGAATCCCGAATTTCTGAAAGAGGGCGCC
GCCGTCGAAGACTTCACGCGCCCGGACCGCATCATCCTTGGCTGCGACGACGATGTGCCGGGCGAAAAGGCACGCGAGCT
GATGAAGCGTCTCTACGCGCCGTTCAACCGCAATCGCGAGCGCACGCTGTACATGGACGTGCGCTCCGCCGAATTCACGA
AGTACGCGGCCAACGCCATGCTCGCCACGCGCATCTCGTTCATGAACGACCTCGCGAATCTCGCCGATCGCGTCGGTGCC
GATATCGAAGCTGTGCGCCGCGGCATGGGCTCGGACCCGCGCATCGGCTACGACTTCCTGTACGCGGGCTGCGGCTACGG
CGGCTCGTGCTTCCCGAAGGACGTGCAGGCGCTGATCCGCACGGGTAGCGAGATGGGCCACAGCCTGCGCATTCTCGAAG
CCGTGGAAGCCGTCAACGAGACGCAGAAGAGGATCGTCGCGCAGAAGATCGTCGCGCACATGGGCGAGGACTTGTCGGAC
CGCACGTTCGCCGTCTGGGGCCTGGCGTTCAAGCCGAACACGGACGACATGCGCGAAGCGCCGAGCCGTGCGCTGATCGC
CGAACTGCTCGCCCGCGGCGCGAAGGTCGTCGCCTATGACCCTGTTGCCATCGACGAAGCGAAGCGGGTGTTCGCGCTCG
ATCTGCAAGGCAAGCCGCAGCAGCTCGCGCGTCTCGCGTTCGCCGACGAAGAGATGCAGGCGGCCGCCCAGGCCGACGCG
CTCGTGATCCTCACCGAATGGAAGGTCTTCAAGAGCCCGGACTTCGACAGCCTGAAGGCGCAATTGAAGACGCCGCTGAT
TTTCGACGGCCGCAACCTGTACGAACCGGAGGCGATGCGCGAACTCGGCATCGAGTATCACGCGATCGGCCGTCGGGCCG
CGCAGCTGCAACGCACGCCGCACGACGCGGCCCCGTCGTTGACGACGCTGGCGACGGCCGCCGCGCTGTAA

Upstream 100 bases:

>100_bases
GGGCAGCAACGCGTACTGAGCGCCGCGCGCCACGCACAACACAGCGGCAACACCGGCCGTTCCGCATTCACTAAACCATT
CAATCTCCGAGGTGTAATTC

Downstream 100 bases:

>100_bases
CGCTGCAAGACCTCATCGACCTGTACGGAGGCCGCCCATGTTCGCGAACGTGCTGATCGTCTGCCATGCCAACGTGTGCC
GCTCGCCCGCCGCCGAGTGG

Product: nucleotide sugar dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 476; Mature: 476

Protein sequence:

>476_residues
MNLTIVGTGYVGLVTGACLADIGHDVFCLDVDQRKIDVLNNGGVPIHEPGLLEIIARNRKAGRLTFSTNIEAAVAHGDIQ
FIAVGTPPDEDGSADLQYVLAAARNIGRHMNGFKVIVDKSTVPVGTARRVAHAVQDELDQRGLQQMFSVVSNPEFLKEGA
AVEDFTRPDRIILGCDDDVPGEKARELMKRLYAPFNRNRERTLYMDVRSAEFTKYAANAMLATRISFMNDLANLADRVGA
DIEAVRRGMGSDPRIGYDFLYAGCGYGGSCFPKDVQALIRTGSEMGHSLRILEAVEAVNETQKRIVAQKIVAHMGEDLSD
RTFAVWGLAFKPNTDDMREAPSRALIAELLARGAKVVAYDPVAIDEAKRVFALDLQGKPQQLARLAFADEEMQAAAQADA
LVILTEWKVFKSPDFDSLKAQLKTPLIFDGRNLYEPEAMRELGIEYHAIGRRAAQLQRTPHDAAPSLTTLATAAAL

Sequences:

>Translated_476_residues
MNLTIVGTGYVGLVTGACLADIGHDVFCLDVDQRKIDVLNNGGVPIHEPGLLEIIARNRKAGRLTFSTNIEAAVAHGDIQ
FIAVGTPPDEDGSADLQYVLAAARNIGRHMNGFKVIVDKSTVPVGTARRVAHAVQDELDQRGLQQMFSVVSNPEFLKEGA
AVEDFTRPDRIILGCDDDVPGEKARELMKRLYAPFNRNRERTLYMDVRSAEFTKYAANAMLATRISFMNDLANLADRVGA
DIEAVRRGMGSDPRIGYDFLYAGCGYGGSCFPKDVQALIRTGSEMGHSLRILEAVEAVNETQKRIVAQKIVAHMGEDLSD
RTFAVWGLAFKPNTDDMREAPSRALIAELLARGAKVVAYDPVAIDEAKRVFALDLQGKPQQLARLAFADEEMQAAAQADA
LVILTEWKVFKSPDFDSLKAQLKTPLIFDGRNLYEPEAMRELGIEYHAIGRRAAQLQRTPHDAAPSLTTLATAAAL
>Mature_476_residues
MNLTIVGTGYVGLVTGACLADIGHDVFCLDVDQRKIDVLNNGGVPIHEPGLLEIIARNRKAGRLTFSTNIEAAVAHGDIQ
FIAVGTPPDEDGSADLQYVLAAARNIGRHMNGFKVIVDKSTVPVGTARRVAHAVQDELDQRGLQQMFSVVSNPEFLKEGA
AVEDFTRPDRIILGCDDDVPGEKARELMKRLYAPFNRNRERTLYMDVRSAEFTKYAANAMLATRISFMNDLANLADRVGA
DIEAVRRGMGSDPRIGYDFLYAGCGYGGSCFPKDVQALIRTGSEMGHSLRILEAVEAVNETQKRIVAQKIVAHMGEDLSD
RTFAVWGLAFKPNTDDMREAPSRALIAELLARGAKVVAYDPVAIDEAKRVFALDLQGKPQQLARLAFADEEMQAAAQADA
LVILTEWKVFKSPDFDSLKAQLKTPLIFDGRNLYEPEAMRELGIEYHAIGRRAAQLQRTPHDAAPSLTTLATAAAL

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=480, Percent_Identity=35.4166666666667, Blast_Score=268, Evalue=9e-72,
Organism=Homo sapiens, GI296040438, Length=383, Percent_Identity=35.509138381201, Blast_Score=215, Evalue=6e-56,
Organism=Homo sapiens, GI296040443, Length=329, Percent_Identity=35.5623100303951, Blast_Score=187, Evalue=2e-47,
Organism=Escherichia coli, GI1788340, Length=365, Percent_Identity=27.1232876712329, Blast_Score=148, Evalue=7e-37,
Organism=Escherichia coli, GI48994968, Length=449, Percent_Identity=26.7260579064588, Blast_Score=139, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI17560350, Length=469, Percent_Identity=35.6076759061834, Blast_Score=261, Evalue=7e-70,
Organism=Drosophila melanogaster, GI17136908, Length=473, Percent_Identity=35.0951374207188, Blast_Score=258, Evalue=7e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 52055; Mature: 52055

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLTIVGTGYVGLVTGACLADIGHDVFCLDVDQRKIDVLNNGGVPIHEPGLLEIIARNRK
CEEEEEECCHHHHHHHHHHHHCCCCEEEEECCCCEEEEECCCCCCCCCCCHHHHHHCCCC
AGRLTFSTNIEAAVAHGDIQFIAVGTPPDEDGSADLQYVLAAARNIGRHMNGFKVIVDKS
CCEEEEECCCCEEEEECCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECC
TVPVGTARRVAHAVQDELDQRGLQQMFSVVSNPEFLKEGAAVEDFTRPDRIILGCDDDVP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHCCCCCEEEEECCCCCC
GEKARELMKRLYAPFNRNRERTLYMDVRSAEFTKYAANAMLATRISFMNDLANLADRVGA
CHHHHHHHHHHHCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DIEAVRRGMGSDPRIGYDFLYAGCGYGGSCFPKDVQALIRTGSEMGHSLRILEAVEAVNE
CHHHHHHCCCCCCCCCHHHHEECCCCCCCCCHHHHHHHHHCCHHHCHHHHHHHHHHHHHH
TQKRIVAQKIVAHMGEDLSDRTFAVWGLAFKPNTDDMREAPSRALIAELLARGAKVVAYD
HHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCHHHHCCHHHHHHHHHHCCCEEEEEC
PVAIDEAKRVFALDLQGKPQQLARLAFADEEMQAAAQADALVILTEWKVFKSPDFDSLKA
CCCCCCCCEEEEEECCCCHHHHHHHHHCCHHHHHHHCCCEEEEEEECEEECCCCHHHHHH
QLKTPLIFDGRNLYEPEAMRELGIEYHAIGRRAAQLQRTPHDAAPSLTTLATAAAL
HHCCCEEECCCCCCCCHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure
MNLTIVGTGYVGLVTGACLADIGHDVFCLDVDQRKIDVLNNGGVPIHEPGLLEIIARNRK
CEEEEEECCHHHHHHHHHHHHCCCCEEEEECCCCEEEEECCCCCCCCCCCHHHHHHCCCC
AGRLTFSTNIEAAVAHGDIQFIAVGTPPDEDGSADLQYVLAAARNIGRHMNGFKVIVDKS
CCEEEEECCCCEEEEECCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECC
TVPVGTARRVAHAVQDELDQRGLQQMFSVVSNPEFLKEGAAVEDFTRPDRIILGCDDDVP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHCCCCCEEEEECCCCCC
GEKARELMKRLYAPFNRNRERTLYMDVRSAEFTKYAANAMLATRISFMNDLANLADRVGA
CHHHHHHHHHHHCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DIEAVRRGMGSDPRIGYDFLYAGCGYGGSCFPKDVQALIRTGSEMGHSLRILEAVEAVNE
CHHHHHHCCCCCCCCCHHHHEECCCCCCCCCHHHHHHHHHCCHHHCHHHHHHHHHHHHHH
TQKRIVAQKIVAHMGEDLSDRTFAVWGLAFKPNTDDMREAPSRALIAELLARGAKVVAYD
HHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCHHHHCCHHHHHHHHHHCCCEEEEEC
PVAIDEAKRVFALDLQGKPQQLARLAFADEEMQAAAQADALVILTEWKVFKSPDFDSLKA
CCCCCCCCEEEEEECCCCHHHHHHHHHCCHHHHHHHCCCEEEEEEECEEECCCCHHHHHH
QLKTPLIFDGRNLYEPEAMRELGIEYHAIGRRAAQLQRTPHDAAPSLTTLATAAAL
HHCCCEEECCCCCCCCHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]