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The map label for this gene is xanB [H]

Identifier: 186475821

GI number: 186475821

Start: 1184705

End: 1186222

Strand: Reverse

Name: xanB [H]

Synonym: Bphy_1056

Alternate gene names: 186475821

Gene position: 1186222-1184705 (Counterclockwise)

Preceding gene: 186475834

Following gene: 186475818

Centisome position: 34.09

GC content: 62.52

Gene sequence:

>1518_bases
ATGACTGCTACGGCGTCAGCCGTCGAGAATCGACAGGCGAATTCATCCTGCCTCAACGTGAAGCTCAAGGTTCATCCTGT
GATCCTTGCCGGCGGATCAGGCACGCGCCTGTGGCCGATGTCGCGCGAACAGCATCCGAAGCAGCTGATCGGCCTGCTTG
GCGAAGACTCGCTGCTGCAATCGACGACCCGTCGCCTCGACGGACTCGATGCCGGCTACCCCGTCGCGGAACAGCTGGTG
GTGGTCTGCAACGAAGAGCACCGCTTCACGACGGCCGAACAGCTTCGCCTGAGCGGCGTGCAGAGCCGTCTGATTCTCGA
ACCGTGCGCCCGCGACACGGCGCCGGCGCTGACGATCGCCGCGCTCTCGGTACTCGCGCACGACGAGGACGGCATTATGG
TCGTGATGCCCGCCGATCACGCTGTCACCCATCCCGAAGGATTTCATGCCGCCGTTGCTACCGGCGTGCAGCACGCGGCC
AACGGCCACATCGTGACGATGGGCATCGTGCCCTCGCGTGCGGAAACGGGTTATGGCTACATTCGCATCGGCGCACGGTT
GCCTGCGCGCGAAGGCGTAATCGACGCGCATCAACTGGATCGCTTCGTCGAAAAGCCGCACTACGAACTCGCGCAGCACT
ATGTCGAGTCGAAAGAGTACTGGTGGAACAGCGGCATCTTCATTCTGCGTGCGTCGACGTGGCTCCAGGCGGTGCGCCAT
TTCCAGCCTGAGATTGCCGAAGCCTGCGAAGCCGCGTATGCGCAAGGCACGACCGACGGCGAATTCTTTCGCGTGCGGCG
CGACGCGTTTGGCGGCTGTCCGTCGAATTCGATCGACTACGCGGTGATGGAAAAACTCGGCAACGACACGTCTGTCTGCT
CCGGTGTCGTCGTGCCGCTCGAGGCCGGCTGGTCCGATGTCGGTTCATGGGACGCGATCTGGGACATCCTGCCGAAAGAC
GGCGACCAGAACGTCGCCCGCGGCAATGTGATGTTCGAAGGCGCGGCATCGACGTTCGCGCATTCCGAAGGACGCCTGAT
CGCCTGCGTGGGCACGCAGGATCTCGTCGTCGTCGAAACGGACGACGCGATTCTTGTCGCCGACAAGCGCCGCGTGCAGG
ACGTGAAGAAAGTGGTTGGCCGAATCCGCGAGAAGCACGGCGCGGAAGCCGTGAACCATCGCAAGGTGCACCGCCCGTGG
GGCCACTACGATTCCGTCGACATGGGCGAACGCTTCCAGGTGAAGCGCATTGTGGTGAAGCCGGGCGCGCAGTTGTCGCT
GCAGATGCATCACCATCGCGCGGAACACTGGATCGTTGTACGCGGCACGGCACTTGTCACGCGCGGCGAAGAGCGCTTCA
TCGTCTCCGAAAACGAATCGGCGTACATTCCGCTTGGCATCAAGCATCGGCTGGAAAATCCCGGCAAGATGCCGCTCGAG
ATCATCGAGGTGCAATCGGGCTCGTATCTCGGCGAAGACGACATTGTGCGCTTCGACGACACGTACGGACGTCAATAA

Upstream 100 bases:

>100_bases
TTTTATCGTAATTATTTAATAGAAATTGAACGCGGATTTATTGACGCATTACGACGTGATAAAAACGGAGCCATTCATCC
CGCTTCGAGGAGTTATCACC

Downstream 100 bases:

>100_bases
CGCATCGCGCGGTGACGGGTTGCTGCCCGTCACCGCTTCTCCATGTCGTCGGAAGTGCGTCGAGTGAAATGCGCAAGCGA
CGCGCGTGATGCGCGAGCTT

Product: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase

Products: NA

Alternate protein names: Mannose-6-phosphate isomerase; Phosphohexomutase; Phosphomannose isomerase; PMI; Mannose-1-phosphate guanylyl transferase; GDP-mannose pyrophosphorylase; GMP; GMPP [H]

Number of amino acids: Translated: 505; Mature: 504

Protein sequence:

>505_residues
MTATASAVENRQANSSCLNVKLKVHPVILAGGSGTRLWPMSREQHPKQLIGLLGEDSLLQSTTRRLDGLDAGYPVAEQLV
VVCNEEHRFTTAEQLRLSGVQSRLILEPCARDTAPALTIAALSVLAHDEDGIMVVMPADHAVTHPEGFHAAVATGVQHAA
NGHIVTMGIVPSRAETGYGYIRIGARLPAREGVIDAHQLDRFVEKPHYELAQHYVESKEYWWNSGIFILRASTWLQAVRH
FQPEIAEACEAAYAQGTTDGEFFRVRRDAFGGCPSNSIDYAVMEKLGNDTSVCSGVVVPLEAGWSDVGSWDAIWDILPKD
GDQNVARGNVMFEGAASTFAHSEGRLIACVGTQDLVVVETDDAILVADKRRVQDVKKVVGRIREKHGAEAVNHRKVHRPW
GHYDSVDMGERFQVKRIVVKPGAQLSLQMHHHRAEHWIVVRGTALVTRGEERFIVSENESAYIPLGIKHRLENPGKMPLE
IIEVQSGSYLGEDDIVRFDDTYGRQ

Sequences:

>Translated_505_residues
MTATASAVENRQANSSCLNVKLKVHPVILAGGSGTRLWPMSREQHPKQLIGLLGEDSLLQSTTRRLDGLDAGYPVAEQLV
VVCNEEHRFTTAEQLRLSGVQSRLILEPCARDTAPALTIAALSVLAHDEDGIMVVMPADHAVTHPEGFHAAVATGVQHAA
NGHIVTMGIVPSRAETGYGYIRIGARLPAREGVIDAHQLDRFVEKPHYELAQHYVESKEYWWNSGIFILRASTWLQAVRH
FQPEIAEACEAAYAQGTTDGEFFRVRRDAFGGCPSNSIDYAVMEKLGNDTSVCSGVVVPLEAGWSDVGSWDAIWDILPKD
GDQNVARGNVMFEGAASTFAHSEGRLIACVGTQDLVVVETDDAILVADKRRVQDVKKVVGRIREKHGAEAVNHRKVHRPW
GHYDSVDMGERFQVKRIVVKPGAQLSLQMHHHRAEHWIVVRGTALVTRGEERFIVSENESAYIPLGIKHRLENPGKMPLE
IIEVQSGSYLGEDDIVRFDDTYGRQ
>Mature_504_residues
TATASAVENRQANSSCLNVKLKVHPVILAGGSGTRLWPMSREQHPKQLIGLLGEDSLLQSTTRRLDGLDAGYPVAEQLVV
VCNEEHRFTTAEQLRLSGVQSRLILEPCARDTAPALTIAALSVLAHDEDGIMVVMPADHAVTHPEGFHAAVATGVQHAAN
GHIVTMGIVPSRAETGYGYIRIGARLPAREGVIDAHQLDRFVEKPHYELAQHYVESKEYWWNSGIFILRASTWLQAVRHF
QPEIAEACEAAYAQGTTDGEFFRVRRDAFGGCPSNSIDYAVMEKLGNDTSVCSGVVVPLEAGWSDVGSWDAIWDILPKDG
DQNVARGNVMFEGAASTFAHSEGRLIACVGTQDLVVVETDDAILVADKRRVQDVKKVVGRIREKHGAEAVNHRKVHRPWG
HYDSVDMGERFQVKRIVVKPGAQLSLQMHHHRAEHWIVVRGTALVTRGEERFIVSENESAYIPLGIKHRLENPGKMPLEI
IEVQSGSYLGEDDIVRFDDTYGRQ

Specific function: Involved in xanthan production [H]

COG id: COG0836

COG function: function code M; Mannose-1-phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannose-6-phosphate isomerase type 2 family [H]

Homologues:

Organism=Escherichia coli, GI1788362, Length=485, Percent_Identity=50.7216494845361, Blast_Score=478, Evalue=1e-136,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR006375
- InterPro:   IPR001538
- InterPro:   IPR005835
- InterPro:   IPR014710 [H]

Pfam domain/function: PF01050 MannoseP_isomer; PF00483 NTP_transferase [H]

EC number: =5.3.1.8; =2.7.7.13 [H]

Molecular weight: Translated: 55728; Mature: 55596

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATASAVENRQANSSCLNVKLKVHPVILAGGSGTRLWPMSREQHPKQLIGLLGEDSLLQ
CCCCHHHHHCCCCCCCEEEEEEEEEEEEEECCCCCEECCCCCCCCHHHHHHHCCCCHHHH
STTRRLDGLDAGYPVAEQLVVVCNEEHRFTTAEQLRLSGVQSRLILEPCARDTAPALTIA
HHHHHHCCCCCCCCHHHEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
ALSVLAHDEDGIMVVMPADHAVTHPEGFHAAVATGVQHAANGHIVTMGIVPSRAETGYGY
HHHHHEECCCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCEE
IRIGARLPAREGVIDAHQLDRFVEKPHYELAQHYVESKEYWWNSGIFILRASTWLQAVRH
EEECCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHEEECCCEEEEECHHHHHHHHH
FQPEIAEACEAAYAQGTTDGEFFRVRRDAFGGCPSNSIDYAVMEKLGNDTSVCSGVVVPL
CCHHHHHHHHHHHHCCCCCCHHEEEEHHHCCCCCCCCCCHHHHHHCCCCCHHHCCEEEEE
EAGWSDVGSWDAIWDILPKDGDQNVARGNVMFEGAASTFAHSEGRLIACVGTQDLVVVET
ECCCCCCCCHHHHHCCCCCCCCCCCCCCCEEEECCHHHHCCCCCCEEEEECCCCEEEEEC
DDAILVADKRRVQDVKKVVGRIREKHGAEAVNHRKVHRPWGHYDSVDMGERFQVKRIVVK
CCEEEEECHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCCCCEEEEEEEEC
PGAQLSLQMHHHRAEHWIVVRGTALVTRGEERFIVSENESAYIPLGIKHRLENPGKMPLE
CCCCEEEEEECCCCCEEEEEECEEEEECCCCEEEEECCCCEEEEECHHHHCCCCCCCCEE
IIEVQSGSYLGEDDIVRFDDTYGRQ
EEEECCCCCCCCCCEEEECCCCCCC
>Mature Secondary Structure 
TATASAVENRQANSSCLNVKLKVHPVILAGGSGTRLWPMSREQHPKQLIGLLGEDSLLQ
CCCHHHHHCCCCCCCEEEEEEEEEEEEEECCCCCEECCCCCCCCHHHHHHHCCCCHHHH
STTRRLDGLDAGYPVAEQLVVVCNEEHRFTTAEQLRLSGVQSRLILEPCARDTAPALTIA
HHHHHHCCCCCCCCHHHEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
ALSVLAHDEDGIMVVMPADHAVTHPEGFHAAVATGVQHAANGHIVTMGIVPSRAETGYGY
HHHHHEECCCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCEE
IRIGARLPAREGVIDAHQLDRFVEKPHYELAQHYVESKEYWWNSGIFILRASTWLQAVRH
EEECCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHEEECCCEEEEECHHHHHHHHH
FQPEIAEACEAAYAQGTTDGEFFRVRRDAFGGCPSNSIDYAVMEKLGNDTSVCSGVVVPL
CCHHHHHHHHHHHHCCCCCCHHEEEEHHHCCCCCCCCCCHHHHHHCCCCCHHHCCEEEEE
EAGWSDVGSWDAIWDILPKDGDQNVARGNVMFEGAASTFAHSEGRLIACVGTQDLVVVET
ECCCCCCCCHHHHHCCCCCCCCCCCCCCCEEEECCHHHHCCCCCCEEEEECCCCEEEEEC
DDAILVADKRRVQDVKKVVGRIREKHGAEAVNHRKVHRPWGHYDSVDMGERFQVKRIVVK
CCEEEEECHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCCCCEEEEEEEEC
PGAQLSLQMHHHRAEHWIVVRGTALVTRGEERFIVSENESAYIPLGIKHRLENPGKMPLE
CCCCEEEEEECCCCCEEEEEECEEEEECCCCEEEEECCCCEEEEECHHHHCCCCCCCCEE
IIEVQSGSYLGEDDIVRFDDTYGRQ
EEEECCCCCCCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1370280; 11589581 [H]