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The map label for this gene is surA [C]

Identifier: 186475788

GI number: 186475788

Start: 1153203

End: 1153982

Strand: Reverse

Name: surA [C]

Synonym: Bphy_1023

Alternate gene names: 186475788

Gene position: 1153982-1153203 (Counterclockwise)

Preceding gene: 186475789

Following gene: 186475786

Centisome position: 33.17

GC content: 58.97

Gene sequence:

>780_bases
ATGACCTTGAAGAACACCCGCTACTGGGTTTCGCTGGCTGCATTCGCGGCCGCGCCTGCATTTGCACAGAACATCGCCGT
CGTGAACGGCACGCCGATTCCGAAGTCGCGCGCCGACGCGCTGGTTGCGCAACTCGTGCAACAGGGTCAACAGGATTCAC
CCAAGCTGCAACAGGCTGTTCGTGAAGAACTTGTGAACCGCGAAATCCTGATGCAGGAAGCGATCCGCGAAGGCATTCCG
TCGAAGCCGGAAGTCAAGGCGCAGGTTGCCGTTGCGCAGCAGACAGTCGTGTTGCGCGCGCTGATCGAGAGCTATGTGAA
GAAGAACCAGCCGACGGATGCCGAAGTGAAGGCGAAGTACGACGAGCTGGTGAAACAGATTGGCGGCAAGGAATATCACC
TGCACCACATCTTGGTGGAGAACGAGCAGCAGGCAAAGGATCTGATCGCGAAGATCAAGGGTGGCGCGAGCTTCGAAGAT
CTGGCGAAGCAGTTCTCGAAGGATCCGGGATCGGGCAAGAACGGTGGCGACCTCGACTGGTCGGACCCGAAGGCTTACGT
GCCCGAATTTGCCGCTGCCGCGGAGAAGCTGCAGAAAGGCCAGATGACGGACGAGCCGGTTCATACGCAGTTTGGCTGGC
ACATCATTCGTGTCGACGATGTGCGCCAGACGCCGCCTCCGCCGTTCGAGCAGGTGAAGGCGCAGATCGCGCAGCAGATG
CAGCAGGAAAAGCTGCAGGCTTTTGAAGAGAATCTGCGGGCCAAGGCAAAGGTTCAGTGA

Upstream 100 bases:

>100_bases
GATGCGCTGGCCGATGCCATGCAACGCGGCATTCACGCTCTCGCCATCACGGCTTATACGCCAGAAGAATTCAATTTGCT
GTCCCGTTAGGAAACTTCCG

Downstream 100 bases:

>100_bases
CCTTGGCAGTCTGGTTTGAAGGAAGCCGCCTTTGGGCGGCTTTTTTATTTTTTGCTTCAGGTTGTTTGCCTTCGCGAGGC
AATGTTTTTCTTGCAGATGC

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase; Rotamase [H]

Number of amino acids: Translated: 259; Mature: 258

Protein sequence:

>259_residues
MTLKNTRYWVSLAAFAAAPAFAQNIAVVNGTPIPKSRADALVAQLVQQGQQDSPKLQQAVREELVNREILMQEAIREGIP
SKPEVKAQVAVAQQTVVLRALIESYVKKNQPTDAEVKAKYDELVKQIGGKEYHLHHILVENEQQAKDLIAKIKGGASFED
LAKQFSKDPGSGKNGGDLDWSDPKAYVPEFAAAAEKLQKGQMTDEPVHTQFGWHIIRVDDVRQTPPPPFEQVKAQIAQQM
QQEKLQAFEENLRAKAKVQ

Sequences:

>Translated_259_residues
MTLKNTRYWVSLAAFAAAPAFAQNIAVVNGTPIPKSRADALVAQLVQQGQQDSPKLQQAVREELVNREILMQEAIREGIP
SKPEVKAQVAVAQQTVVLRALIESYVKKNQPTDAEVKAKYDELVKQIGGKEYHLHHILVENEQQAKDLIAKIKGGASFED
LAKQFSKDPGSGKNGGDLDWSDPKAYVPEFAAAAEKLQKGQMTDEPVHTQFGWHIIRVDDVRQTPPPPFEQVKAQIAQQM
QQEKLQAFEENLRAKAKVQ
>Mature_258_residues
TLKNTRYWVSLAAFAAAPAFAQNIAVVNGTPIPKSRADALVAQLVQQGQQDSPKLQQAVREELVNREILMQEAIREGIPS
KPEVKAQVAVAQQTVVLRALIESYVKKNQPTDAEVKAKYDELVKQIGGKEYHLHHILVENEQQAKDLIAKIKGGASFEDL
AKQFSKDPGSGKNGGDLDWSDPKAYVPEFAAAAEKLQKGQMTDEPVHTQFGWHIIRVDDVRQTPPPPFEQVKAQIAQQMQ
QEKLQAFEENLRAKAKVQ

Specific function: Assist In The Folding Of Extracytoplasmic Proteins. Essential For The Survival Of E.Coli In Stationary Phase. [C]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786238, Length=108, Percent_Identity=42.5925925925926, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1790211, Length=83, Percent_Identity=46.9879518072289, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1786645, Length=148, Percent_Identity=28.3783783783784, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17537235, Length=97, Percent_Identity=37.1134020618557, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 28795; Mature: 28664

Theoretical pI: Translated: 7.87; Mature: 7.87

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLKNTRYWVSLAAFAAAPAFAQNIAVVNGTPIPKSRADALVAQLVQQGQQDSPKLQQAV
CCCCCHHHHHHHHHHHHHHHHHHCEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHH
REELVNREILMQEAIREGIPSKPEVKAQVAVAQQTVVLRALIESYVKKNQPTDAEVKAKY
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
DELVKQIGGKEYHLHHILVENEQQAKDLIAKIKGGASFEDLAKQFSKDPGSGKNGGDLDW
HHHHHHHCCCEEEEEEEEECCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCC
SDPKAYVPEFAAAAEKLQKGQMTDEPVHTQFGWHIIRVDDVRQTPPPPFEQVKAQIAQQM
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHH
QQEKLQAFEENLRAKAKVQ
HHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TLKNTRYWVSLAAFAAAPAFAQNIAVVNGTPIPKSRADALVAQLVQQGQQDSPKLQQAV
CCCCHHHHHHHHHHHHHHHHHHCEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHH
REELVNREILMQEAIREGIPSKPEVKAQVAVAQQTVVLRALIESYVKKNQPTDAEVKAKY
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
DELVKQIGGKEYHLHHILVENEQQAKDLIAKIKGGASFEDLAKQFSKDPGSGKNGGDLDW
HHHHHHHCCCEEEEEEEEECCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCC
SDPKAYVPEFAAAAEKLQKGQMTDEPVHTQFGWHIIRVDDVRQTPPPPFEQVKAQIAQQM
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHH
QQEKLQAFEENLRAKAKVQ
HHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12910271 [H]