Click here to switch to the map view.

The map label for this gene is dapE [H]

Identifier: 186475761

GI number: 186475761

Start: 1115827

End: 1117005

Strand: Reverse

Name: dapE [H]

Synonym: Bphy_0996

Alternate gene names: 186475761

Gene position: 1117005-1115827 (Counterclockwise)

Preceding gene: 186475762

Following gene: 186475760

Centisome position: 32.11

GC content: 69.04

Gene sequence:

>1179_bases
ATGACGGACGCGGTCGACACGGCATCCATCGTCGAACTGTTGACGGCGCTCGTGCGCCTGCCGAGCCGCGGCGGCATCGA
TGCGTGCACGCCCGTGCTCGAATGCGTCGAAGCGTGGTTCGCCGCACGCGGGGTCGGCACGCGCCGCCTGCTTTGCGCCG
ATGGCGAACCGCTCGCGCTCTACGCCGAAATCCGCGGCGCCTCGCCGCGCCCGCATTACGTGCTCAACGCGACGCTCGAC
ACGGCCGGCTTCGGCGACGAATCGACCTGGACCTGGCCGCCGCTCAGCGCGCAGGTGGTCGACGGCTGGCTGCATGGACG
CGGCAGCGCCGACAGCAAGGCGGCCGTCGCGATCTTCGCGCACCTCGCCGTCGCGTTCGCGCGGCGCGCCGATTCATTCG
CGGGTACGCTCGGCGTGCTGTTCGATCTCGACGAGCACACGGGCCGTTTCGGGGGCGCCCGCGCGTTCTTCGACGAAACG
AGCGCGCCCAAACCCGACGGCGTATTCATCGGCTATCCGGGTATCGACCGCATCGTGGTCGGCGCGCGCGGATTCATGCG
CGCGAAACTGGTCGTGCGCGGCGTCGCGGCGCATTCGGGCGCGAGCAGCACGCGCGGACTCAACGCGGCGACACGCGGCG
CGCGCCTCGCTGCGGCGTTGAGCGACACGTCACTGCCCTTCGATCACGCCTTCGGACGCGCTGCCCAACTCACCGTCACG
GGCATTCGCGCGGGCGACGGCACCTTCACCCGCGTTCCCGAACGCTGCGAACTCGACATCGATTGCCGCCTCACGCCGGA
CTTCGATGCCGCGCACGCTCAGCGCGTGATCGAAGGCATGGTTCGCGAACAGGATGCGACCTACGACGCGTCGCTCGCGA
CGTCGATCGAATGGCTACCCGGCTGGCCTGCGTATCGCATGACGGATTCACATCCGCTCGCGAGTGCGCTGTATCACGCG
GCAAACGACGAACTGGGCGCGAAACGGGCGTGCGTCGTCGCCGGGCCGTCGAACATCGGCAACTACCTCGCGTCGCTGGG
CATTCCCGCGCTGTGCGGCTTCGGCGTGCAATGCGCCGGCATCCACGCGGCCGACGAACGCATCGAACTCGCTTCCATTG
CGCCCGTCTACCGCATTTACGAACGTGCGCTGCTCGCGTTGCTTGCCGCCGCGAACTGA

Upstream 100 bases:

>100_bases
TTCACGGTGCGCGTCGCGACCGTGAAGGAGACGCTGCGCGCGCTCGGCACACCGTCCAGGGGCGCCGCGGATCAGCGCGT
GGCGTCGTCGCGCTAGCGGC

Downstream 100 bases:

>100_bases
CGGCCCCTGCCGCTCACGTGCCGTTGCTGCATCGCGCAAAGCCCCGCCGTACGGGCGTCTGCCGCGATGAGCTTTGGCTG
GTCGAGCGGTTTTTGGGTAT

Product: peptidase dimerisation domain-containing protein

Products: NA

Alternate protein names: SDAP desuccinylase; N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase [H]

Number of amino acids: Translated: 392; Mature: 391

Protein sequence:

>392_residues
MTDAVDTASIVELLTALVRLPSRGGIDACTPVLECVEAWFAARGVGTRRLLCADGEPLALYAEIRGASPRPHYVLNATLD
TAGFGDESTWTWPPLSAQVVDGWLHGRGSADSKAAVAIFAHLAVAFARRADSFAGTLGVLFDLDEHTGRFGGARAFFDET
SAPKPDGVFIGYPGIDRIVVGARGFMRAKLVVRGVAAHSGASSTRGLNAATRGARLAAALSDTSLPFDHAFGRAAQLTVT
GIRAGDGTFTRVPERCELDIDCRLTPDFDAAHAQRVIEGMVREQDATYDASLATSIEWLPGWPAYRMTDSHPLASALYHA
ANDELGAKRACVVAGPSNIGNYLASLGIPALCGFGVQCAGIHAADERIELASIAPVYRIYERALLALLAAAN

Sequences:

>Translated_392_residues
MTDAVDTASIVELLTALVRLPSRGGIDACTPVLECVEAWFAARGVGTRRLLCADGEPLALYAEIRGASPRPHYVLNATLD
TAGFGDESTWTWPPLSAQVVDGWLHGRGSADSKAAVAIFAHLAVAFARRADSFAGTLGVLFDLDEHTGRFGGARAFFDET
SAPKPDGVFIGYPGIDRIVVGARGFMRAKLVVRGVAAHSGASSTRGLNAATRGARLAAALSDTSLPFDHAFGRAAQLTVT
GIRAGDGTFTRVPERCELDIDCRLTPDFDAAHAQRVIEGMVREQDATYDASLATSIEWLPGWPAYRMTDSHPLASALYHA
ANDELGAKRACVVAGPSNIGNYLASLGIPALCGFGVQCAGIHAADERIELASIAPVYRIYERALLALLAAAN
>Mature_391_residues
TDAVDTASIVELLTALVRLPSRGGIDACTPVLECVEAWFAARGVGTRRLLCADGEPLALYAEIRGASPRPHYVLNATLDT
AGFGDESTWTWPPLSAQVVDGWLHGRGSADSKAAVAIFAHLAVAFARRADSFAGTLGVLFDLDEHTGRFGGARAFFDETS
APKPDGVFIGYPGIDRIVVGARGFMRAKLVVRGVAAHSGASSTRGLNAATRGARLAAALSDTSLPFDHAFGRAAQLTVTG
IRAGDGTFTRVPERCELDIDCRLTPDFDAAHAQRVIEGMVREQDATYDASLATSIEWLPGWPAYRMTDSHPLASALYHAA
NDELGAKRACVVAGPSNIGNYLASLGIPALCGFGVQCAGIHAADERIELASIAPVYRIYERALLALLAAAN

Specific function: Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bact

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. DapE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788816, Length=388, Percent_Identity=23.7113402061856, Blast_Score=78, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005941
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.18 [H]

Molecular weight: Translated: 41349; Mature: 41218

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDAVDTASIVELLTALVRLPSRGGIDACTPVLECVEAWFAARGVGTRRLLCADGEPLAL
CCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEE
YAEIRGASPRPHYVLNATLDTAGFGDESTWTWPPLSAQVVDGWLHGRGSADSKAAVAIFA
EEEECCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHH
HLAVAFARRADSFAGTLGVLFDLDEHTGRFGGARAFFDETSAPKPDGVFIGYPGIDRIVV
HHHHHHHHHHHHHHCCEEEEEECCHHCCCCCCCHHECCCCCCCCCCCEEEECCCCCEEEE
GARGFMRAKLVVRGVAAHSGASSTRGLNAATRGARLAAALSDTSLPFDHAFGRAAQLTVT
CCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCHHEEEECCCCCCCHHHHCCCEEEEEEE
GIRAGDGTFTRVPERCELDIDCRLTPDFDAAHAQRVIEGMVREQDATYDASLATSIEWLP
EEECCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCHHHHEECCCC
GWPAYRMTDSHPLASALYHAANDELGAKRACVVAGPSNIGNYLASLGIPALCGFGVQCAG
CCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHCCCHHHHCCCCEEEC
IHAADERIELASIAPVYRIYERALLALLAAAN
CCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TDAVDTASIVELLTALVRLPSRGGIDACTPVLECVEAWFAARGVGTRRLLCADGEPLAL
CCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEE
YAEIRGASPRPHYVLNATLDTAGFGDESTWTWPPLSAQVVDGWLHGRGSADSKAAVAIFA
EEEECCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHH
HLAVAFARRADSFAGTLGVLFDLDEHTGRFGGARAFFDETSAPKPDGVFIGYPGIDRIVV
HHHHHHHHHHHHHHCCEEEEEECCHHCCCCCCCHHECCCCCCCCCCCEEEECCCCCEEEE
GARGFMRAKLVVRGVAAHSGASSTRGLNAATRGARLAAALSDTSLPFDHAFGRAAQLTVT
CCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCHHEEEECCCCCCCHHHHCCCEEEEEEE
GIRAGDGTFTRVPERCELDIDCRLTPDFDAAHAQRVIEGMVREQDATYDASLATSIEWLP
EEECCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCHHHHEECCCC
GWPAYRMTDSHPLASALYHAANDELGAKRACVVAGPSNIGNYLASLGIPALCGFGVQCAG
CCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHCCCHHHHCCCCEEEC
IHAADERIELASIAPVYRIYERALLALLAAAN
CCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA