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The map label for this gene is argE [H]

Identifier: 186475760

GI number: 186475760

Start: 1114435

End: 1115694

Strand: Reverse

Name: argE [H]

Synonym: Bphy_0995

Alternate gene names: 186475760

Gene position: 1115694-1114435 (Counterclockwise)

Preceding gene: 186475761

Following gene: 186475759

Centisome position: 32.07

GC content: 63.17

Gene sequence:

>1260_bases
ATGTCACTGGTCGCTGACAAAGCGCTGTCCGCACAAACGTCCCCGCCTTCCGCCGATTCCGCCCGCGCTTCGTCTCCCGC
TTCGCTTCCCTGGGTCACGCGTCTCGTGTCGATGGACACGGTCAGCCGCAATCCGAATCTCGGACTGATTGAAACAGTGC
GCGATTCGCTGCGCGAGCGCGGTATCGAAGCGACGCTCACGCACGACGAAAGCGGCAAGTGGGCGAACCTGTTCGCGACC
ATTCCGGCGCATGACGGCGAGACCCAGGGCGGGATCGTGCTATCGGGCCATACGGACGTCGTGCCCGTCGACGGCCAGAA
GTGGGACAGCGATCCCTTCAAGCCGGAAGTGCGCGGCGACAAGCTTTATGGGCGTGGCACGTGCGACATGAAAGGCTTTA
TCGGCGCAGCATTGACGCTCGTGCCGCGGATGCAGCAGACGAAGCTCGCCAAGCCGATCCACCTCGCGTTCTCGTTCGAC
GAAGAAGTAGGCTGCGTAGGCGCGCCGCTGATGATCGCCGATCTGATGAAACGCGGCATCAAGCCGGACGGCTGCATTGT
CGGCGAGCCGACCAGCATGCGCCCCATCATCGCGCACAAGGGCATCAATGCGTACCAGTGCTGCGTGCGCGGCTTCGCGG
CGCATTCGTCGCTGACGCCGAAGGGCTTGAACGCGATCGAATATGCGGCGCGCCTGATCTGCTTCATCCGCGACATGGCC
GACCAGTTCCGCGATCAAGGTCCGTTCGATCAACTCTACGACGTCCCGTTTACGACGGCGCAGACCAGCACGATCAAGGG
CGGCAACGCGATCAACACGGTCCCGGCCGAATGCAGCTTCGAGTTCGAGTTCCGCAATCTGCCCACGCTGGACCCCGAGC
CGATCTTCGCGCGCATCGATCAATACGCGCGCGAAACCCTGCTGCCCAAAATGAAGCGCGAGCACGAAGCGGCCGCGATC
GAGTTCACGAAAATCGCTGCGGCGCCTGGGCTCGACGCAACGGAGCAGGCGGCCATCACGCAACTGGTGCGCGCGCTCAC
CGCCGATCAGGACAAGCGCAAGGTCGCGTACGGCACGGAAGCGGGCCTGTTCTCGCTGGCGGGCATTCCGAGCATCGTAT
GCGGTCCCGGCGACATCCAGCAGGCGCACAAGGCAAATGAGTTCGTCACGCTGGACCAACTCGCGCAGTGCGAACGGTTC
CTCGAGAAGTTCATTCACAGCATGTCGGTCGATGCGGCGCACATTGACCCAAGCAGTTGA

Upstream 100 bases:

>100_bases
CGCGCAAAGCCCCGCCGTACGGGCGTCTGCCGCGATGAGCTTTGGCTGGTCGAGCGGTTTTTGGGTATCATCGAAACACA
CTCAAGCTGGAGTTCATGTC

Downstream 100 bases:

>100_bases
GAAGGCAACAAGCACAACAACACGGCACAAGAACGCGGACCTCACCCACTTGCGAGTACGCACGCCATGTCCACTGCCAC
GCCGCACCACACCGACCGCA

Product: acetylornithine deacetylase

Products: NA

Alternate protein names: AO; Acetylornithinase; N-acetylornithinase; NAO [H]

Number of amino acids: Translated: 419; Mature: 418

Protein sequence:

>419_residues
MSLVADKALSAQTSPPSADSARASSPASLPWVTRLVSMDTVSRNPNLGLIETVRDSLRERGIEATLTHDESGKWANLFAT
IPAHDGETQGGIVLSGHTDVVPVDGQKWDSDPFKPEVRGDKLYGRGTCDMKGFIGAALTLVPRMQQTKLAKPIHLAFSFD
EEVGCVGAPLMIADLMKRGIKPDGCIVGEPTSMRPIIAHKGINAYQCCVRGFAAHSSLTPKGLNAIEYAARLICFIRDMA
DQFRDQGPFDQLYDVPFTTAQTSTIKGGNAINTVPAECSFEFEFRNLPTLDPEPIFARIDQYARETLLPKMKREHEAAAI
EFTKIAAAPGLDATEQAAITQLVRALTADQDKRKVAYGTEAGLFSLAGIPSIVCGPGDIQQAHKANEFVTLDQLAQCERF
LEKFIHSMSVDAAHIDPSS

Sequences:

>Translated_419_residues
MSLVADKALSAQTSPPSADSARASSPASLPWVTRLVSMDTVSRNPNLGLIETVRDSLRERGIEATLTHDESGKWANLFAT
IPAHDGETQGGIVLSGHTDVVPVDGQKWDSDPFKPEVRGDKLYGRGTCDMKGFIGAALTLVPRMQQTKLAKPIHLAFSFD
EEVGCVGAPLMIADLMKRGIKPDGCIVGEPTSMRPIIAHKGINAYQCCVRGFAAHSSLTPKGLNAIEYAARLICFIRDMA
DQFRDQGPFDQLYDVPFTTAQTSTIKGGNAINTVPAECSFEFEFRNLPTLDPEPIFARIDQYARETLLPKMKREHEAAAI
EFTKIAAAPGLDATEQAAITQLVRALTADQDKRKVAYGTEAGLFSLAGIPSIVCGPGDIQQAHKANEFVTLDQLAQCERF
LEKFIHSMSVDAAHIDPSS
>Mature_418_residues
SLVADKALSAQTSPPSADSARASSPASLPWVTRLVSMDTVSRNPNLGLIETVRDSLRERGIEATLTHDESGKWANLFATI
PAHDGETQGGIVLSGHTDVVPVDGQKWDSDPFKPEVRGDKLYGRGTCDMKGFIGAALTLVPRMQQTKLAKPIHLAFSFDE
EVGCVGAPLMIADLMKRGIKPDGCIVGEPTSMRPIIAHKGINAYQCCVRGFAAHSSLTPKGLNAIEYAARLICFIRDMAD
QFRDQGPFDQLYDVPFTTAQTSTIKGGNAINTVPAECSFEFEFRNLPTLDPEPIFARIDQYARETLLPKMKREHEAAAIE
FTKIAAAPGLDATEQAAITQLVRALTADQDKRKVAYGTEAGLFSLAGIPSIVCGPGDIQQAHKANEFVTLDQLAQCERFL
EKFIHSMSVDAAHIDPSS

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. ArgE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790395, Length=333, Percent_Identity=30.9309309309309, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1788816, Length=336, Percent_Identity=26.4880952380952, Blast_Score=86, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17551016, Length=341, Percent_Identity=25.2199413489736, Blast_Score=75, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010169
- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.16 [H]

Molecular weight: Translated: 45385; Mature: 45254

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLVADKALSAQTSPPSADSARASSPASLPWVTRLVSMDTVSRNPNLGLIETVRDSLRER
CCCCHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHC
GIEATLTHDESGKWANLFATIPAHDGETQGGIVLSGHTDVVPVDGQKWDSDPFKPEVRGD
CCEEEEEECCCCCEEEEEEEECCCCCCCCCCEEEECCCCEEECCCCCCCCCCCCCCCCCC
KLYGRGTCDMKGFIGAALTLVPRMQQTKLAKPIHLAFSFDEEVGCVGAPLMIADLMKRGI
EEECCCCCCHHHHHHHHHHHHCCHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCC
KPDGCIVGEPTSMRPIIAHKGINAYQCCVRGFAAHSSLTPKGLNAIEYAARLICFIRDMA
CCCCEEECCCCCCCCHHHHCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
DQFRDQGPFDQLYDVPFTTAQTSTIKGGNAINTVPAECSFEFEFRNLPTLDPEPIFARID
HHHHCCCCHHHHHCCCCCCCCCCEECCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHH
QYARETLLPKMKREHEAAAIEFTKIAAAPGLDATEQAAITQLVRALTADQDKRKVAYGTE
HHHHHHHHHHHHHHHHHHHEEHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCEEECCCC
AGLFSLAGIPSIVCGPGDIQQAHKANEFVTLDQLAQCERFLEKFIHSMSVDAAHIDPSS
CCHHHHCCCCEEEECCCHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SLVADKALSAQTSPPSADSARASSPASLPWVTRLVSMDTVSRNPNLGLIETVRDSLRER
CCCHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHC
GIEATLTHDESGKWANLFATIPAHDGETQGGIVLSGHTDVVPVDGQKWDSDPFKPEVRGD
CCEEEEEECCCCCEEEEEEEECCCCCCCCCCEEEECCCCEEECCCCCCCCCCCCCCCCCC
KLYGRGTCDMKGFIGAALTLVPRMQQTKLAKPIHLAFSFDEEVGCVGAPLMIADLMKRGI
EEECCCCCCHHHHHHHHHHHHCCHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCC
KPDGCIVGEPTSMRPIIAHKGINAYQCCVRGFAAHSSLTPKGLNAIEYAARLICFIRDMA
CCCCEEECCCCCCCCHHHHCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
DQFRDQGPFDQLYDVPFTTAQTSTIKGGNAINTVPAECSFEFEFRNLPTLDPEPIFARID
HHHHCCCCHHHHHCCCCCCCCCCEECCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHH
QYARETLLPKMKREHEAAAIEFTKIAAAPGLDATEQAAITQLVRALTADQDKRKVAYGTE
HHHHHHHHHHHHHHHHHHHEEHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCEEECCCC
AGLFSLAGIPSIVCGPGDIQQAHKANEFVTLDQLAQCERFLEKFIHSMSVDAAHIDPSS
CCHHHHCCCCEEEECCCHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]