Click here to switch to the map view.

The map label for this gene is yfbQ [H]

Identifier: 186475695

GI number: 186475695

Start: 1033030

End: 1034277

Strand: Direct

Name: yfbQ [H]

Synonym: Bphy_0930

Alternate gene names: 186475695

Gene position: 1033030-1034277 (Clockwise)

Preceding gene: 186475682

Following gene: 186475696

Centisome position: 29.69

GC content: 63.22

Gene sequence:

>1248_bases
GTGCCCGTCGTGAAACCGATACTCAAATCCAACAAGCTGTTGAACGTCTGCTACGACATTCGCGGGCCCGTCCTCGAACA
CGCGAAGCGCCTCGAAGAGGAAGGCCACCGCATCATCAAGCTGAACATCGGCAATCTGGCGCCGTTTGGTTTCGATGCGC
CGGACGAAATCATTCAGGACATGATCCGCAATCTGCCCGTTTCGTCGGGTTATTCGGATTCGAAGGGCGTGTTCGCCGCG
CGCAAGGCGATCATGCACTACGCGCAGCACAAAGGCGTCGTGGGCGTCGAACTGGACGACATCTACATCGGCAACGGCGC
GTCCGAGCTGATCGTGATGGCGCTGCAGGCGCTGCTGAACGACGGCGACGAGGTACTGCTGCCCGCGCCGGACTATCCGC
TGTGGACGGCGGGCGTGAGCCTGTCGGGCGGTACGCCCGTGCATTACGTCTGCGACGAGTCGAACGCGTGGATGCCCGAC
CTCGACGACATCCGCGCGAAGATCACGCCGAACACGAAAGCGCTCGTCGTGATCAACCCGAACAACCCGACGGGCGCGCT
GTATTCGGACGAACTGCTGCTCGGCCTGATCGAGATCGCGCGCCAGCACGGCCTCGTGATCTTCGCGGACGAGGTCTACG
ACAAGATCGTCTACGACGGCAAGGCGCACACGTCGATGGCCGCGCTGTCGGAAGACGTGCTCACCGTCACGTTCAACAGC
CTGTCGAAGAGCTACCGCTCGTGCGGCTATCGCGCGGGCTGGATGTGGGTGTCCGGCCTGACGGGCGAGAACCGCCGCCG
CGCGAAGGACTACTTCGAAGGCCTCGGCATTCTCGCTTCGATGCGCCTGTGCCCCAACGTGCCGGGCCAGTACGCGATCC
AGACGGCGCTCGGCGGCTATCAGAGCATCAACGAGCTGATCATGCCGGGCGGGCGCCTGCACAAGCAGCGTGAGCTCGCG
TACGACATGCTGACCGCGATTCCAGGCGTGACGTGCGTGAAGCCCGAGGCGGCGTTGTACATGTTCCCGCGTCTCGACCC
GAATCTGTACCCGATCGAGAACGACCAGCAGTTCATTCTCGATCTGCTGCTGGAAGAGCGCGTGCTGCTCGTGCAGGGCA
GCGGCTTCAACTGGAAGACGCCGGATCACTTCCGCGTCGTGTTCCTGCCGAACGTCGACGATCTCGCCGATTCGATCCAC
CGGATCGGGCGTTTCCTCGACGGCTATCGCAAACGCCACGCGGCCTGA

Upstream 100 bases:

>100_bases
CGCCTGCCCGCGCCGCGCGGCTGCCGCAGTTCCCGTTCTCATGGCCTGCCCGCCGCGTGGGGCGAGAGCTCCGTTGTTCC
GCTCATTAATCCAGGATGAA

Downstream 100 bases:

>100_bases
GCGCATTGCATCCGCGCCCGAACCAATTTACCAATCTCTCACTCGAAATACACGCTGCATGGAACCGATCAAAGTTGGAC
TGCTGGGCTTCGGCACGGTA

Product: aminotransferase AlaT

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 415; Mature: 414

Protein sequence:

>415_residues
MPVVKPILKSNKLLNVCYDIRGPVLEHAKRLEEEGHRIIKLNIGNLAPFGFDAPDEIIQDMIRNLPVSSGYSDSKGVFAA
RKAIMHYAQHKGVVGVELDDIYIGNGASELIVMALQALLNDGDEVLLPAPDYPLWTAGVSLSGGTPVHYVCDESNAWMPD
LDDIRAKITPNTKALVVINPNNPTGALYSDELLLGLIEIARQHGLVIFADEVYDKIVYDGKAHTSMAALSEDVLTVTFNS
LSKSYRSCGYRAGWMWVSGLTGENRRRAKDYFEGLGILASMRLCPNVPGQYAIQTALGGYQSINELIMPGGRLHKQRELA
YDMLTAIPGVTCVKPEAALYMFPRLDPNLYPIENDQQFILDLLLEERVLLVQGSGFNWKTPDHFRVVFLPNVDDLADSIH
RIGRFLDGYRKRHAA

Sequences:

>Translated_415_residues
MPVVKPILKSNKLLNVCYDIRGPVLEHAKRLEEEGHRIIKLNIGNLAPFGFDAPDEIIQDMIRNLPVSSGYSDSKGVFAA
RKAIMHYAQHKGVVGVELDDIYIGNGASELIVMALQALLNDGDEVLLPAPDYPLWTAGVSLSGGTPVHYVCDESNAWMPD
LDDIRAKITPNTKALVVINPNNPTGALYSDELLLGLIEIARQHGLVIFADEVYDKIVYDGKAHTSMAALSEDVLTVTFNS
LSKSYRSCGYRAGWMWVSGLTGENRRRAKDYFEGLGILASMRLCPNVPGQYAIQTALGGYQSINELIMPGGRLHKQRELA
YDMLTAIPGVTCVKPEAALYMFPRLDPNLYPIENDQQFILDLLLEERVLLVQGSGFNWKTPDHFRVVFLPNVDDLADSIH
RIGRFLDGYRKRHAA
>Mature_414_residues
PVVKPILKSNKLLNVCYDIRGPVLEHAKRLEEEGHRIIKLNIGNLAPFGFDAPDEIIQDMIRNLPVSSGYSDSKGVFAAR
KAIMHYAQHKGVVGVELDDIYIGNGASELIVMALQALLNDGDEVLLPAPDYPLWTAGVSLSGGTPVHYVCDESNAWMPDL
DDIRAKITPNTKALVVINPNNPTGALYSDELLLGLIEIARQHGLVIFADEVYDKIVYDGKAHTSMAALSEDVLTVTFNSL
SKSYRSCGYRAGWMWVSGLTGENRRRAKDYFEGLGILASMRLCPNVPGQYAIQTALGGYQSINELIMPGGRLHKQRELAY
DMLTAIPGVTCVKPEAALYMFPRLDPNLYPIENDQQFILDLLLEERVLLVQGSGFNWKTPDHFRVVFLPNVDDLADSIHR
IGRFLDGYRKRHAA

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI19263340, Length=469, Percent_Identity=29.4243070362473, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI215599424, Length=381, Percent_Identity=31.2335958005249, Blast_Score=162, Evalue=5e-40,
Organism=Homo sapiens, GI4885351, Length=450, Percent_Identity=26.6666666666667, Blast_Score=142, Evalue=4e-34,
Organism=Homo sapiens, GI4507369, Length=415, Percent_Identity=27.4698795180723, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI95147551, Length=267, Percent_Identity=28.8389513108614, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI169881279, Length=267, Percent_Identity=28.8389513108614, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI56713254, Length=165, Percent_Identity=29.0909090909091, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI56713256, Length=165, Percent_Identity=29.0909090909091, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI187936925, Length=372, Percent_Identity=23.9247311827957, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI14211921, Length=372, Percent_Identity=23.9247311827957, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI169881281, Length=157, Percent_Identity=31.2101910828025, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI149944424, Length=367, Percent_Identity=21.7983651226158, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1788627, Length=408, Percent_Identity=64.4607843137255, Blast_Score=566, Evalue=1e-163,
Organism=Escherichia coli, GI1788722, Length=398, Percent_Identity=25.3768844221106, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1786816, Length=267, Percent_Identity=24.3445692883895, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17567663, Length=383, Percent_Identity=28.4595300261097, Blast_Score=144, Evalue=6e-35,
Organism=Caenorhabditis elegans, GI71981209, Length=490, Percent_Identity=25.7142857142857, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI71981215, Length=329, Percent_Identity=27.355623100304, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71994476, Length=164, Percent_Identity=33.5365853658537, Blast_Score=95, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI71994472, Length=164, Percent_Identity=33.5365853658537, Blast_Score=95, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17567369, Length=175, Percent_Identity=31.4285714285714, Blast_Score=91, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6323118, Length=384, Percent_Identity=29.1666666666667, Blast_Score=144, Evalue=3e-35,
Organism=Saccharomyces cerevisiae, GI6320317, Length=381, Percent_Identity=29.3963254593176, Blast_Score=139, Evalue=7e-34,
Organism=Saccharomyces cerevisiae, GI6322401, Length=236, Percent_Identity=28.3898305084746, Blast_Score=100, Evalue=6e-22,
Organism=Drosophila melanogaster, GI18859735, Length=417, Percent_Identity=28.2973621103118, Blast_Score=151, Evalue=7e-37,
Organism=Drosophila melanogaster, GI45551451, Length=470, Percent_Identity=26.5957446808511, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24641770, Length=470, Percent_Identity=26.5957446808511, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24641760, Length=470, Percent_Identity=26.5957446808511, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24641768, Length=470, Percent_Identity=26.5957446808511, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24641766, Length=470, Percent_Identity=26.5957446808511, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24641764, Length=470, Percent_Identity=26.5957446808511, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI28573069, Length=179, Percent_Identity=26.8156424581006, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24646114, Length=179, Percent_Identity=26.8156424581006, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI28573067, Length=179, Percent_Identity=26.8156424581006, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI28573065, Length=179, Percent_Identity=26.8156424581006, Blast_Score=79, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 46051; Mature: 45919

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVVKPILKSNKLLNVCYDIRGPVLEHAKRLEEEGHRIIKLNIGNLAPFGFDAPDEIIQD
CCCCHHHHHCCCCEEHHHHCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHH
MIRNLPVSSGYSDSKGVFAARKAIMHYAQHKGVVGVELDDIYIGNGASELIVMALQALLN
HHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEECCEEECCCHHHHHHHHHHHHHC
DGDEVLLPAPDYPLWTAGVSLSGGTPVHYVCDESNAWMPDLDDIRAKITPNTKALVVINP
CCCEEEEECCCCCEEECCEECCCCCCEEEEECCCCCCCCCHHHCEEEECCCCEEEEEECC
NNPTGALYSDELLLGLIEIARQHGLVIFADEVYDKIVYDGKAHTSMAALSEDVLTVTFNS
CCCCCCEEHHHHHHHHHHHHHHCCEEEEEHHHHHHHHCCCCCHHHHHHHHCCCEEEEHHH
LSKSYRSCGYRAGWMWVSGLTGENRRRAKDYFEGLGILASMRLCPNVPGQYAIQTALGGY
HHHHHHHCCCEECEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCH
QSINELIMPGGRLHKQRELAYDMLTAIPGVTCVKPEAALYMFPRLDPNLYPIENDQQFIL
HHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEECCCCEEEEEECCCCCCCCCCCCHHHHH
DLLLEERVLLVQGSGFNWKTPDHFRVVFLPNVDDLADSIHRIGRFLDGYRKRHAA
HHHHHCCEEEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PVVKPILKSNKLLNVCYDIRGPVLEHAKRLEEEGHRIIKLNIGNLAPFGFDAPDEIIQD
CCCHHHHHCCCCEEHHHHCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHH
MIRNLPVSSGYSDSKGVFAARKAIMHYAQHKGVVGVELDDIYIGNGASELIVMALQALLN
HHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEECCEEECCCHHHHHHHHHHHHHC
DGDEVLLPAPDYPLWTAGVSLSGGTPVHYVCDESNAWMPDLDDIRAKITPNTKALVVINP
CCCEEEEECCCCCEEECCEECCCCCCEEEEECCCCCCCCCHHHCEEEECCCCEEEEEECC
NNPTGALYSDELLLGLIEIARQHGLVIFADEVYDKIVYDGKAHTSMAALSEDVLTVTFNS
CCCCCCEEHHHHHHHHHHHHHHCCEEEEEHHHHHHHHCCCCCHHHHHHHHCCCEEEEHHH
LSKSYRSCGYRAGWMWVSGLTGENRRRAKDYFEGLGILASMRLCPNVPGQYAIQTALGGY
HHHHHHHCCCEECEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCH
QSINELIMPGGRLHKQRELAYDMLTAIPGVTCVKPEAALYMFPRLDPNLYPIENDQQFIL
HHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEECCCCEEEEEECCCCCCCCCCCCHHHHH
DLLLEERVLLVQGSGFNWKTPDHFRVVFLPNVDDLADSIHRIGRFLDGYRKRHAA
HHHHHCCEEEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]