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The map label for this gene is pgsA [H]

Identifier: 186475617

GI number: 186475617

Start: 952283

End: 952873

Strand: Direct

Name: pgsA [H]

Synonym: Bphy_0852

Alternate gene names: 186475617

Gene position: 952283-952873 (Clockwise)

Preceding gene: 186475616

Following gene: 186475619

Centisome position: 27.37

GC content: 59.9

Gene sequence:

>591_bases
ATGCCGTTTAATTTTCCGATCTTCCTGACGTGGCTGCGGATAGTATTGATTCCGCTCGTGGTGGGCGTGTTCTATCTGCC
GGACATGATGCTGAGTCCGATGCACCGTAATCTGGCGGCAGCGACGATCTTCATCCTCGCTGCGCTGACCGACTGGTTCG
ACGGCTTTCTCGCGCGTAAATGGAACCAGACGTCGGCTTTCGGCGCGTTCCTCGACCCCGTCGCCGACAAGCTGATGGTG
ACGGCCGCGCTGCTGGTGCTCGTGCAACTGTCCCGGCTGGACTCGGCGATCGCGCTGGTGATCGTCGGTCGCGAGATCGC
GATTTCCGCGCTGCGCGAATGGATGGCGCAAATAGGCGCATCGAAGAGCGTTGCCGTGAATTCGCTCGGCAAGTTCAAAA
CGGCCTGCCAGATGACGGCCATTCCGATGCTGCTGTTTTATGGGCCGCTGTCGTTCGGCGCGTTTTCGATTGACACGCGC
GTATGGGGTTTGTGGCTCATCTATCTCGCTGCGTTCCTGACGATCTGGTCGATGCTGTACTACATGAAGCTCGCCTGGCC
GCAGATCCGCGAGCGCGGCGGCATGGCGTAA

Upstream 100 bases:

>100_bases
GCCCCACAGCCGCGATGCGCGCGCGCCGGGGCGTTGCTTGTGGCGCGCCGGGTGAACCGGCACAATTGCATCTCTTATCT
CAGAACGTAGCGCCAGCCCC

Downstream 100 bases:

>100_bases
TCGAAGCGCGGCGAGGGGCCTCACTAAAATTTTCAATCGCTCGTACAAAAAGAGTTGACACGATTCCGTGCCTTCTACAT
AATCTCGTTTCTCCGGTGCA

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 196; Mature: 195

Protein sequence:

>196_residues
MPFNFPIFLTWLRIVLIPLVVGVFYLPDMMLSPMHRNLAAATIFILAALTDWFDGFLARKWNQTSAFGAFLDPVADKLMV
TAALLVLVQLSRLDSAIALVIVGREIAISALREWMAQIGASKSVAVNSLGKFKTACQMTAIPMLLFYGPLSFGAFSIDTR
VWGLWLIYLAAFLTIWSMLYYMKLAWPQIRERGGMA

Sequences:

>Translated_196_residues
MPFNFPIFLTWLRIVLIPLVVGVFYLPDMMLSPMHRNLAAATIFILAALTDWFDGFLARKWNQTSAFGAFLDPVADKLMV
TAALLVLVQLSRLDSAIALVIVGREIAISALREWMAQIGASKSVAVNSLGKFKTACQMTAIPMLLFYGPLSFGAFSIDTR
VWGLWLIYLAAFLTIWSMLYYMKLAWPQIRERGGMA
>Mature_195_residues
PFNFPIFLTWLRIVLIPLVVGVFYLPDMMLSPMHRNLAAATIFILAALTDWFDGFLARKWNQTSAFGAFLDPVADKLMVT
AALLVLVQLSRLDSAIALVIVGREIAISALREWMAQIGASKSVAVNSLGKFKTACQMTAIPMLLFYGPLSFGAFSIDTRV
WGLWLIYLAAFLTIWSMLYYMKLAWPQIRERGGMA

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=187, Percent_Identity=49.1978609625668, Blast_Score=152, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 21947; Mature: 21815

Theoretical pI: Translated: 10.00; Mature: 10.00

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFNFPIFLTWLRIVLIPLVVGVFYLPDMMLSPMHRNLAAATIFILAALTDWFDGFLARK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WNQTSAFGAFLDPVADKLMVTAALLVLVQLSRLDSAIALVIVGREIAISALREWMAQIGA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SKSVAVNSLGKFKTACQMTAIPMLLFYGPLSFGAFSIDTRVWGLWLIYLAAFLTIWSMLY
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
YMKLAWPQIRERGGMA
HHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PFNFPIFLTWLRIVLIPLVVGVFYLPDMMLSPMHRNLAAATIFILAALTDWFDGFLARK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WNQTSAFGAFLDPVADKLMVTAALLVLVQLSRLDSAIALVIVGREIAISALREWMAQIGA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SKSVAVNSLGKFKTACQMTAIPMLLFYGPLSFGAFSIDTRVWGLWLIYLAAFLTIWSMLY
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
YMKLAWPQIRERGGMA
HHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]