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The map label for this gene is degP [H]

Identifier: 186475602

GI number: 186475602

Start: 935266

End: 936774

Strand: Direct

Name: degP [H]

Synonym: Bphy_0837

Alternate gene names: 186475602

Gene position: 935266-936774 (Clockwise)

Preceding gene: 186475601

Following gene: 186475603

Centisome position: 26.88

GC content: 64.74

Gene sequence:

>1509_bases
ATGACGATTCTCTCGGTGCGCAAATTCTTCGCGGCCGCAGTACTGGTGGCTTGCCTGCCGCTCGCGCCGCACACGGCGTC
GGCGGCGCCTGCTGCCAATCTGCCCGATTTCACCGATCTGGTCGACAAGGTCGGGCCGGCCGTCGTCAACATTCGCACCA
CGGCGCGCGTCTCCAACAGCACGCGCGGGTTGCCGCCCGGCATGGACGACGGCGACATGTCTGAGTTCTTCCGGCGGTTC
TTCGGCATTCCGATGCCTAACTCGCCGCAGTCGCCGGGCACGCCGAATTCGCCGCGGGGCGGTAACAACGGCAACAACGA
CCAGGATCAATCGCCCGACAACGGTCCCGATACCGAGCAGAACAGCGGCGTCGGCTCGGGTTTCATCCTGTCGCCGGACG
GTTACGTGATGACTAACGCGCACGTGATCGACGACGCGGACACGATCTACGTGACGCTCACTGACAAACGCGAATTCAAG
GCCAAGCTGATTGGCGTCGACGAGCGCACGGACGTGGCCGTCGTCAAGATCAATGCAGCGAACCTGCCGACGGTACCGAT
CGGCGATTCCAACAAGGTGCGCGTCGGCGAGTGGGTTGTCGCGATCGGCTCGCCGTTCGGGCTCGAGAACACGGTGACGG
CGGGCATCGTCAGTGCGAAGGGGCGCGACACGGGCGACTATCTGCCGTTCATCCAGACGGATGTGGCCGTGAATCCAGGC
AATTCGGGCGGCCCGCTGATCAACATGCAGGGCGAGGTGATTGGCATCAACTCGCAGATCTACAGCCGGACGGGCGGCTT
CATGGGCATCTCGTTCGCGATTCCAATCGACGAAGCGATGCGCGTCGCCGATCAGCTGAAGGCGTCGGGCAAGGTCGTGC
GCGGACGGATTGCCGTCGCGATCGGAGAGGTGACGAAAGACGTTGCGGATTCGCTCGGCTTGCCGAAGGCGCAGGGTGCG
CTCGTCAGCAGCGTCGAGCCGGGCGGCCCGGCCGACAAGGCAGGCGTGCAACCTGGTGACATCATCCTCAAGTTCAACGG
TCACAACGTGGACACGGCGACGGATCTGCCGCGCATGGTCGGCGATACGAAGCCGGGCACGAAGGCGACGATCACGCTGT
GGCGCAAAGGCCAGACCCGCGAGGTGCCGGTGACCGTCGCCGAAATGCAGCCTGAGAAGGCCGCGAAGGCCGACCAGAAG
AAGGCGCCGACGCCCAAGCCGCGTGCATCGAACGCGTTGGGCGTGGCGGTCAGCGATATCCCCGCCGAACAGATGAAGTC
GCTGAAGCTGCATAACGGCGTGCAGGTCGATGCCGTCGACGGTCCGGCCGCGCGTGTGGGCTTGCAACGCGGGGACATCA
TCCTGCGCGTTGGCGACACGGATATCACGAGCGCGAAGCAGTTCGAAGAAGTCACCTCGCATCTCGACGCGTCGAAGATG
GTCGCGCTGCTGGTCCGCCGCGGGGAAAACACGCAGTTCGTGCCCGTTCGTCCGCGCGCGTCGAAGTGA

Upstream 100 bases:

>100_bases
TGGATCACCTTGCTCGGGGAAGTGCCTCAGACCACGTTGCAGCAATTTGCGGCTGCCATAGAATACAAGCCTTCCAGGTA
ATCCTTCGGTTCCCCACGAC

Downstream 100 bases:

>100_bases
CGAACGCGATCGGCCCGGGGGCATCGCTTACGCTCTACGGGCGTGCGTGGTGCCACCTGTGCGATGACATGCGTGCGGCG
CTGGGGCCCTTCCTGACCGA

Product: protease Do

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 502; Mature: 501

Protein sequence:

>502_residues
MTILSVRKFFAAAVLVACLPLAPHTASAAPAANLPDFTDLVDKVGPAVVNIRTTARVSNSTRGLPPGMDDGDMSEFFRRF
FGIPMPNSPQSPGTPNSPRGGNNGNNDQDQSPDNGPDTEQNSGVGSGFILSPDGYVMTNAHVIDDADTIYVTLTDKREFK
AKLIGVDERTDVAVVKINAANLPTVPIGDSNKVRVGEWVVAIGSPFGLENTVTAGIVSAKGRDTGDYLPFIQTDVAVNPG
NSGGPLINMQGEVIGINSQIYSRTGGFMGISFAIPIDEAMRVADQLKASGKVVRGRIAVAIGEVTKDVADSLGLPKAQGA
LVSSVEPGGPADKAGVQPGDIILKFNGHNVDTATDLPRMVGDTKPGTKATITLWRKGQTREVPVTVAEMQPEKAAKADQK
KAPTPKPRASNALGVAVSDIPAEQMKSLKLHNGVQVDAVDGPAARVGLQRGDIILRVGDTDITSAKQFEEVTSHLDASKM
VALLVRRGENTQFVPVRPRASK

Sequences:

>Translated_502_residues
MTILSVRKFFAAAVLVACLPLAPHTASAAPAANLPDFTDLVDKVGPAVVNIRTTARVSNSTRGLPPGMDDGDMSEFFRRF
FGIPMPNSPQSPGTPNSPRGGNNGNNDQDQSPDNGPDTEQNSGVGSGFILSPDGYVMTNAHVIDDADTIYVTLTDKREFK
AKLIGVDERTDVAVVKINAANLPTVPIGDSNKVRVGEWVVAIGSPFGLENTVTAGIVSAKGRDTGDYLPFIQTDVAVNPG
NSGGPLINMQGEVIGINSQIYSRTGGFMGISFAIPIDEAMRVADQLKASGKVVRGRIAVAIGEVTKDVADSLGLPKAQGA
LVSSVEPGGPADKAGVQPGDIILKFNGHNVDTATDLPRMVGDTKPGTKATITLWRKGQTREVPVTVAEMQPEKAAKADQK
KAPTPKPRASNALGVAVSDIPAEQMKSLKLHNGVQVDAVDGPAARVGLQRGDIILRVGDTDITSAKQFEEVTSHLDASKM
VALLVRRGENTQFVPVRPRASK
>Mature_501_residues
TILSVRKFFAAAVLVACLPLAPHTASAAPAANLPDFTDLVDKVGPAVVNIRTTARVSNSTRGLPPGMDDGDMSEFFRRFF
GIPMPNSPQSPGTPNSPRGGNNGNNDQDQSPDNGPDTEQNSGVGSGFILSPDGYVMTNAHVIDDADTIYVTLTDKREFKA
KLIGVDERTDVAVVKINAANLPTVPIGDSNKVRVGEWVVAIGSPFGLENTVTAGIVSAKGRDTGDYLPFIQTDVAVNPGN
SGGPLINMQGEVIGINSQIYSRTGGFMGISFAIPIDEAMRVADQLKASGKVVRGRIAVAIGEVTKDVADSLGLPKAQGAL
VSSVEPGGPADKAGVQPGDIILKFNGHNVDTATDLPRMVGDTKPGTKATITLWRKGQTREVPVTVAEMQPEKAAKADQKK
APTPKPRASNALGVAVSDIPAEQMKSLKLHNGVQVDAVDGPAARVGLQRGDIILRVGDTDITSAKQFEEVTSHLDASKMV
ALLVRRGENTQFVPVRPRASK

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=250, Percent_Identity=39.6, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI22129776, Length=262, Percent_Identity=37.7862595419847, Blast_Score=152, Evalue=9e-37,
Organism=Homo sapiens, GI24308541, Length=250, Percent_Identity=36.4, Blast_Score=149, Evalue=7e-36,
Organism=Homo sapiens, GI7019477, Length=251, Percent_Identity=40.2390438247012, Blast_Score=148, Evalue=9e-36,
Organism=Escherichia coli, GI1789629, Length=490, Percent_Identity=35.9183673469388, Blast_Score=251, Evalue=1e-67,
Organism=Escherichia coli, GI1786356, Length=484, Percent_Identity=34.297520661157, Blast_Score=241, Evalue=9e-65,
Organism=Escherichia coli, GI1789630, Length=273, Percent_Identity=39.9267399267399, Blast_Score=184, Evalue=1e-47,
Organism=Drosophila melanogaster, GI24646839, Length=262, Percent_Identity=37.0229007633588, Blast_Score=159, Evalue=5e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 52732; Mature: 52601

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTILSVRKFFAAAVLVACLPLAPHTASAAPAANLPDFTDLVDKVGPAVVNIRTTARVSNS
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHCCCEEEEEEEEEEECCC
TRGLPPGMDDGDMSEFFRRFFGIPMPNSPQSPGTPNSPRGGNNGNNDQDQSPDNGPDTEQ
CCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
NSGVGSGFILSPDGYVMTNAHVIDDADTIYVTLTDKREFKAKLIGVDERTDVAVVKINAA
CCCCCCCEEECCCCEEEECCEEECCCCEEEEEEECCCCEEEEEECCCCCCCEEEEEEECC
NLPTVPIGDSNKVRVGEWVVAIGSPFGLENTVTAGIVSAKGRDTGDYLPFIQTDVAVNPG
CCCEEECCCCCCEEECEEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCEEEECEEECCC
NSGGPLINMQGEVIGINSQIYSRTGGFMGISFAIPIDEAMRVADQLKASGKVVRGRIAVA
CCCCCEEEECCCEEEECHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHCCCEEEEEEEEE
IGEVTKDVADSLGLPKAQGALVSSVEPGGPADKAGVQPGDIILKFNGHNVDTATDLPRMV
EHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHH
GDTKPGTKATITLWRKGQTREVPVTVAEMQPEKAAKADQKKAPTPKPRASNALGVAVSDI
CCCCCCCEEEEEEEECCCCCCCCEEEECCCCHHHHHHHHHCCCCCCCCCCCCEEEEEECC
PAEQMKSLKLHNGVQVDAVDGPAARVGLQRGDIILRVGDTDITSAKQFEEVTSHLDASKM
CHHHHHHHHHHCCCEEEECCCCHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHCCHHHH
VALLVRRGENTQFVPVRPRASK
HHHHHHCCCCCEEEECCCCCCC
>Mature Secondary Structure 
TILSVRKFFAAAVLVACLPLAPHTASAAPAANLPDFTDLVDKVGPAVVNIRTTARVSNS
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHCCCEEEEEEEEEEECCC
TRGLPPGMDDGDMSEFFRRFFGIPMPNSPQSPGTPNSPRGGNNGNNDQDQSPDNGPDTEQ
CCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
NSGVGSGFILSPDGYVMTNAHVIDDADTIYVTLTDKREFKAKLIGVDERTDVAVVKINAA
CCCCCCCEEECCCCEEEECCEEECCCCEEEEEEECCCCEEEEEECCCCCCCEEEEEEECC
NLPTVPIGDSNKVRVGEWVVAIGSPFGLENTVTAGIVSAKGRDTGDYLPFIQTDVAVNPG
CCCEEECCCCCCEEECEEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCEEEECEEECCC
NSGGPLINMQGEVIGINSQIYSRTGGFMGISFAIPIDEAMRVADQLKASGKVVRGRIAVA
CCCCCEEEECCCEEEECHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHCCCEEEEEEEEE
IGEVTKDVADSLGLPKAQGALVSSVEPGGPADKAGVQPGDIILKFNGHNVDTATDLPRMV
EHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHH
GDTKPGTKATITLWRKGQTREVPVTVAEMQPEKAAKADQKKAPTPKPRASNALGVAVSDI
CCCCCCCEEEEEEEECCCCCCCCEEEECCCCHHHHHHHHHCCCCCCCCCCCCEEEEEECC
PAEQMKSLKLHNGVQVDAVDGPAARVGLQRGDIILRVGDTDITSAKQFEEVTSHLDASKM
CHHHHHHHHHHCCCEEEECCCCHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHCCHHHH
VALLVRRGENTQFVPVRPRASK
HHHHHHCCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7861951 [H]