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The map label for this gene is hldE [H]

Identifier: 186475516

GI number: 186475516

Start: 847658

End: 848620

Strand: Direct

Name: hldE [H]

Synonym: Bphy_0751

Alternate gene names: 186475516

Gene position: 847658-848620 (Clockwise)

Preceding gene: 186475515

Following gene: 186475517

Centisome position: 24.36

GC content: 68.33

Gene sequence:

>963_bases
GTGCCTGAAGGCGCGACGCTCGCGCCCGAGGTGGGCGTCATCGCGCGCGAGCGGCTTGCTGCCGCCCGCGTGCTGGTGGT
TGGGGACGTGATGCTCGATCGCTACTGGTTCGGCGATGTGAACCGGATATCGCCGGAAGCGCCCGTTCCCGTTGTGCTCG
TGCAGCGCCAGGAAGACCGGCTGGGCGGCGCGGCGAACGTCGCGCGCAACGCGGCGGCGCTCGGTGCGCAGGCCGGCTTG
CTGTGTGTAGTCGGCCACGACGAGCCCGGCGAGCGCGTCGTCCAACTGCTCGGCGATAGTGGCGTCGCGTCCCATCTCGA
GCGTGATCCCGAACTGCCGACGACCATCAAGCTACGCGTGTTGTCGCGTCAGCAGCAGCTGCTGCGCGTCGATTTCGAGA
AGGCGCCCGCGCACGAGGCGCTGCTCGCAGGCCTCGCGCGCTATGACGCGCTGCTGCCCGCTCACGACGTAATCCTGATG
TCGGACTATGCGAAGGGTGGCCTCACGCACGTCACGCAGATGATCGCGAAGGCGCGTGCGGCGGGCAAGCCGGTGCTGGT
CGATCCGAAGGGCGACGACTGGGAGCGCTACCGCGGCGCCACGCTGATCACGCCAAACCGCGCGGAGCTGCGCGAGGTGA
TCGGGCATTGGAAGTCCGAGGCCGATCTGCTCGCGCGCGTGACCAGGCTGCGCGCCGAACTCGATCTGACAGCGCTGCTG
CTCACGCGCTCGGAAGAAGGCATGACGTTGTTCTCGGACGAGGGCGTCCTGCACGCGGCTGCCGTAGCGCGTGAAGTGTA
TGATGTGTCCGGCGCGGGCGATACCGTGATCGCGACGCTCGCCGTCATGCTCGGCGCGGGCCTGCCGCTGGACGAAGCCG
TGTCGCTTGCGAATCGCGCCGCAGGCATTGTGGTCGCCAAGCTCGGCACGGCCACTGTCGACTACGACGAACTCTTTCAC
TGA

Upstream 100 bases:

>100_bases
AATCTGTATGAACCCGAGGCGATGTCGGAGCTCGGGATTGACTATCACTCGATTGGACGTCCCTATGCAAGACCCGCTGA
AACTTCATCCGACTCCGGCC

Downstream 100 bases:

>100_bases
TGCCCGCGCGCGCCCGTTTCATCGCGTGGCGCGCGGCGGTTCATCTGCGCATCCGTTGACTCACATCACTGCAGGACGAC
CATGACCCTCATCGTCACCG

Product: rfaE bifunctional protein

Products: NA

Alternate protein names: D-beta-D-heptose 7-phosphate kinase; D-beta-D-heptose 7-phosphotransferase; D-beta-D-heptose 1-phosphate adenosyltransferase [H]

Number of amino acids: Translated: 320; Mature: 319

Protein sequence:

>320_residues
MPEGATLAPEVGVIARERLAAARVLVVGDVMLDRYWFGDVNRISPEAPVPVVLVQRQEDRLGGAANVARNAAALGAQAGL
LCVVGHDEPGERVVQLLGDSGVASHLERDPELPTTIKLRVLSRQQQLLRVDFEKAPAHEALLAGLARYDALLPAHDVILM
SDYAKGGLTHVTQMIAKARAAGKPVLVDPKGDDWERYRGATLITPNRAELREVIGHWKSEADLLARVTRLRAELDLTALL
LTRSEEGMTLFSDEGVLHAAAVAREVYDVSGAGDTVIATLAVMLGAGLPLDEAVSLANRAAGIVVAKLGTATVDYDELFH

Sequences:

>Translated_320_residues
MPEGATLAPEVGVIARERLAAARVLVVGDVMLDRYWFGDVNRISPEAPVPVVLVQRQEDRLGGAANVARNAAALGAQAGL
LCVVGHDEPGERVVQLLGDSGVASHLERDPELPTTIKLRVLSRQQQLLRVDFEKAPAHEALLAGLARYDALLPAHDVILM
SDYAKGGLTHVTQMIAKARAAGKPVLVDPKGDDWERYRGATLITPNRAELREVIGHWKSEADLLARVTRLRAELDLTALL
LTRSEEGMTLFSDEGVLHAAAVAREVYDVSGAGDTVIATLAVMLGAGLPLDEAVSLANRAAGIVVAKLGTATVDYDELFH
>Mature_319_residues
PEGATLAPEVGVIARERLAAARVLVVGDVMLDRYWFGDVNRISPEAPVPVVLVQRQEDRLGGAANVARNAAALGAQAGLL
CVVGHDEPGERVVQLLGDSGVASHLERDPELPTTIKLRVLSRQQQLLRVDFEKAPAHEALLAGLARYDALLPAHDVILMS
DYAKGGLTHVTQMIAKARAAGKPVLVDPKGDDWERYRGATLITPNRAELREVIGHWKSEADLLARVTRLRAELDLTALLL
TRSEEGMTLFSDEGVLHAAAVAREVYDVSGAGDTVIATLAVMLGAGLPLDEAVSLANRAAGIVVAKLGTATVDYDELFH

Specific function: Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose [H]

COG id: COG2870

COG function: function code M; ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the cytidylyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1789432, Length=305, Percent_Identity=52.7868852459016, Blast_Score=285, Evalue=3e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023030
- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR011913
- InterPro:   IPR011914
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2; PF00294 PfkB [H]

EC number: 2.7.-.- [C]

Molecular weight: Translated: 34197; Mature: 34065

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEGATLAPEVGVIARERLAAARVLVVGDVMLDRYWFGDVNRISPEAPVPVVLVQRQEDR
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCHHH
LGGAANVARNAAALGAQAGLLCVVGHDEPGERVVQLLGDSGVASHLERDPELPTTIKLRV
CCCHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCCHHHHHHCCCCCCCEEEHHH
LSRQQQLLRVDFEKAPAHEALLAGLARYDALLPAHDVILMSDYAKGGLTHVTQMIAKARA
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHH
AGKPVLVDPKGDDWERYRGATLITPNRAELREVIGHWKSEADLLARVTRLRAELDLTALL
CCCCEEECCCCCCHHHHCCCEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEEEE
LTRSEEGMTLFSDEGVLHAAAVAREVYDVSGAGDTVIATLAVMLGAGLPLDEAVSLANRA
EECCCCCCEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
AGIVVAKLGTATVDYDELFH
CCEEEEECCCCEECHHHHCC
>Mature Secondary Structure 
PEGATLAPEVGVIARERLAAARVLVVGDVMLDRYWFGDVNRISPEAPVPVVLVQRQEDR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCHHH
LGGAANVARNAAALGAQAGLLCVVGHDEPGERVVQLLGDSGVASHLERDPELPTTIKLRV
CCCHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCCHHHHHHCCCCCCCEEEHHH
LSRQQQLLRVDFEKAPAHEALLAGLARYDALLPAHDVILMSDYAKGGLTHVTQMIAKARA
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHH
AGKPVLVDPKGDDWERYRGATLITPNRAELREVIGHWKSEADLLARVTRLRAELDLTALL
CCCCEEECCCCCCHHHHCCCEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEEEE
LTRSEEGMTLFSDEGVLHAAAVAREVYDVSGAGDTVIATLAVMLGAGLPLDEAVSLANRA
EECCCCCCEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
AGIVVAKLGTATVDYDELFH
CCEEEEECCCCEECHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA