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The map label for this gene is udg [H]

Identifier: 186475515

GI number: 186475515

Start: 846253

End: 847665

Strand: Direct

Name: udg [H]

Synonym: Bphy_0750

Alternate gene names: 186475515

Gene position: 846253-847665 (Clockwise)

Preceding gene: 186475514

Following gene: 186475516

Centisome position: 24.32

GC content: 62.92

Gene sequence:

>1413_bases
ATGAAAATCACCATTATCGGGACGGGTTACGTAGGTCTTGTCACGGGCGCATGTCTTGCCGAAGTCGGCAACGACGTGTT
CTGTCTGGATGTCGATCCGCGCAAGATTGATATTCTCAACAACGGCGGCATGCCGATTCACGAGCCGGGCTTGCAGGAAA
TCATCGCGCGTTCACGCGCGGCCGGCCGCATCACGTTTTCGACGGATGTCGCGGCGAGCGTCGCGCATGGTGAGGTCCAG
TTCATCGCCGTCGGCACACCGCCCGATGAAGACGGTTCCGCCGACCTGCAGTACGTGCTCGAAGCGGCCCGCAACATCGG
CCGCACGATGAACGGGTTCAAGGTGGTGGTCGACAAGTCGACGGTGCCCGTCGGCACCGCGCAACGCGTGCGCGCGGTAA
TCGAGGAAGAACTGGCGAAGCGCGGCTTGAACGGCAGCGCACAGCATGGCTTCTCGATCGTATCGAACCCAGAGTTCCTG
AAGGAAGGCGCGGCCGTCGAAGACTTCATGCGGCCGGACCGCATCGTCGTCGGCGTCGACAACGACGAGCAAGGCGACAA
GGCGCGCGAGAAGATCCGCCGTCTGTACGCGCCGTTCAACCGCAACCACGAACGCACGTTGTACATGGATGTGCGCTCGG
CCGAGTTCACGAAATACGCCGCGAACGCGATGCTCGCGACGCGCATCTCGTTCATGAACGAGATGGCGAATCTGGCCGAT
ACCGTCGGCGCGGACATCGAGGCCGTGCGCCGCGGTATCGGCTCGGATCCGCGCATCGGCTATCACTTCCTTTACGCGGG
CGTCGGCTATGGCGGCTCGTGTTTTCCGAAGGACGTGCAGGCGCTGATCCGCACGGGCGCGGAGCAGGGTCACAACCTGC
GCATTCTCGAGGCCGTCGAAGACGTCAATCACGAGCAGAAGGAAGTGCTGGTGCGCAAGATCACGGGCTCGCTCGGCGAA
GACCTGAGCGGCCGCACGTTCGCCGTGTGGGGGCTGTCGTTCAAGCCGAACACCGACGACATGCGCGAAGCGCCGAGCCG
CCGCGTGATCGGGCAATTGCTTGCGCGCGGTGCGACGGTGCGGGCCTACGATCCCGTCGCGACGACGGAAGCGAAGCGGG
TGTTCGCGCTCGATCTGGCCGGGTTGCCGGAGCAGCAAGCGCGTCTGCATTTCGAGAGCACGCAGGACGAAACGCTTGGC
GGTGCGGACGCGCTCGTGATCGTCACGGAATGGAAGGAATTCAAGAGCCCGGACTTCACGCATCTGAAGTCGCAGCTCAA
GGCGCCGTTGATTTTCGACGGCCGCAATCTGTATGAACCCGAGGCGATGTCGGAGCTCGGGATTGACTATCACTCGATTG
GACGTCCCTATGCAAGACCCGCTGAAACTTCATCCGACTCCGGCCGTGCCTGA

Upstream 100 bases:

>100_bases
GTCGAGTTGACGCGAGGCGCGCGCAGGAGCGTGTTTTGCAACGTAGTCGCGCCGCATCGAAGCGTGGAACTTTGAACCCG
CATCAATTACTGGGAAGCGT

Downstream 100 bases:

>100_bases
AGGCGCGACGCTCGCGCCCGAGGTGGGCGTCATCGCGCGCGAGCGGCTTGCTGCCGCCCGCGTGCTGGTGGTTGGGGACG
TGATGCTCGATCGCTACTGG

Product: nucleotide sugar dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 470; Mature: 470

Protein sequence:

>470_residues
MKITIIGTGYVGLVTGACLAEVGNDVFCLDVDPRKIDILNNGGMPIHEPGLQEIIARSRAAGRITFSTDVAASVAHGEVQ
FIAVGTPPDEDGSADLQYVLEAARNIGRTMNGFKVVVDKSTVPVGTAQRVRAVIEEELAKRGLNGSAQHGFSIVSNPEFL
KEGAAVEDFMRPDRIVVGVDNDEQGDKAREKIRRLYAPFNRNHERTLYMDVRSAEFTKYAANAMLATRISFMNEMANLAD
TVGADIEAVRRGIGSDPRIGYHFLYAGVGYGGSCFPKDVQALIRTGAEQGHNLRILEAVEDVNHEQKEVLVRKITGSLGE
DLSGRTFAVWGLSFKPNTDDMREAPSRRVIGQLLARGATVRAYDPVATTEAKRVFALDLAGLPEQQARLHFESTQDETLG
GADALVIVTEWKEFKSPDFTHLKSQLKAPLIFDGRNLYEPEAMSELGIDYHSIGRPYARPAETSSDSGRA

Sequences:

>Translated_470_residues
MKITIIGTGYVGLVTGACLAEVGNDVFCLDVDPRKIDILNNGGMPIHEPGLQEIIARSRAAGRITFSTDVAASVAHGEVQ
FIAVGTPPDEDGSADLQYVLEAARNIGRTMNGFKVVVDKSTVPVGTAQRVRAVIEEELAKRGLNGSAQHGFSIVSNPEFL
KEGAAVEDFMRPDRIVVGVDNDEQGDKAREKIRRLYAPFNRNHERTLYMDVRSAEFTKYAANAMLATRISFMNEMANLAD
TVGADIEAVRRGIGSDPRIGYHFLYAGVGYGGSCFPKDVQALIRTGAEQGHNLRILEAVEDVNHEQKEVLVRKITGSLGE
DLSGRTFAVWGLSFKPNTDDMREAPSRRVIGQLLARGATVRAYDPVATTEAKRVFALDLAGLPEQQARLHFESTQDETLG
GADALVIVTEWKEFKSPDFTHLKSQLKAPLIFDGRNLYEPEAMSELGIDYHSIGRPYARPAETSSDSGRA
>Mature_470_residues
MKITIIGTGYVGLVTGACLAEVGNDVFCLDVDPRKIDILNNGGMPIHEPGLQEIIARSRAAGRITFSTDVAASVAHGEVQ
FIAVGTPPDEDGSADLQYVLEAARNIGRTMNGFKVVVDKSTVPVGTAQRVRAVIEEELAKRGLNGSAQHGFSIVSNPEFL
KEGAAVEDFMRPDRIVVGVDNDEQGDKAREKIRRLYAPFNRNHERTLYMDVRSAEFTKYAANAMLATRISFMNEMANLAD
TVGADIEAVRRGIGSDPRIGYHFLYAGVGYGGSCFPKDVQALIRTGAEQGHNLRILEAVEDVNHEQKEVLVRKITGSLGE
DLSGRTFAVWGLSFKPNTDDMREAPSRRVIGQLLARGATVRAYDPVATTEAKRVFALDLAGLPEQQARLHFESTQDETLG
GADALVIVTEWKEFKSPDFTHLKSQLKAPLIFDGRNLYEPEAMSELGIDYHSIGRPYARPAETSSDSGRA

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=485, Percent_Identity=35.8762886597938, Blast_Score=261, Evalue=9e-70,
Organism=Homo sapiens, GI296040438, Length=387, Percent_Identity=36.6925064599483, Blast_Score=212, Evalue=5e-55,
Organism=Homo sapiens, GI296040443, Length=329, Percent_Identity=36.7781155015198, Blast_Score=181, Evalue=1e-45,
Organism=Escherichia coli, GI1788340, Length=393, Percent_Identity=28.2442748091603, Blast_Score=156, Evalue=3e-39,
Organism=Escherichia coli, GI48994968, Length=424, Percent_Identity=25.4716981132075, Blast_Score=132, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI17560350, Length=470, Percent_Identity=34.2553191489362, Blast_Score=249, Evalue=2e-66,
Organism=Drosophila melanogaster, GI17136908, Length=476, Percent_Identity=35.7142857142857, Blast_Score=265, Evalue=5e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 51296; Mature: 51296

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITIIGTGYVGLVTGACLAEVGNDVFCLDVDPRKIDILNNGGMPIHEPGLQEIIARSRA
CEEEEEECCHHHHHHHHHHHHHCCCEEEEECCCCEEEEECCCCCCCCCCCHHHHHHHCCC
AGRITFSTDVAASVAHGEVQFIAVGTPPDEDGSADLQYVLEAARNIGRTMNGFKVVVDKS
CCEEEEECCHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECC
TVPVGTAQRVRAVIEEELAKRGLNGSAQHGFSIVSNPEFLKEGAAVEDFMRPDRIVVGVD
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCHHHHHCCCCHHHHCCCCEEEEECC
NDEQGDKAREKIRRLYAPFNRNHERTLYMDVRSAEFTKYAANAMLATRISFMNEMANLAD
CCCCCHHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TVGADIEAVRRGIGSDPRIGYHFLYAGVGYGGSCFPKDVQALIRTGAEQGHNLRILEAVE
HHCCCHHHHHHCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEHHHH
DVNHEQKEVLVRKITGSLGEDLSGRTFAVWGLSFKPNTDDMREAPSRRVIGQLLARGATV
HCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCHHHHCCHHHHHHHHHHCCCEE
RAYDPVATTEAKRVFALDLAGLPEQQARLHFESTQDETLGGADALVIVTEWKEFKSPDFT
EECCCCCCCCCCEEEEEECCCCCHHHHHEEECCCCCCCCCCCCEEEEEEECHHHCCCCHH
HLKSQLKAPLIFDGRNLYEPEAMSELGIDYHSIGRPYARPAETSSDSGRA
HHHHHCCCCEEECCCCCCCCHHHHHHCCCHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKITIIGTGYVGLVTGACLAEVGNDVFCLDVDPRKIDILNNGGMPIHEPGLQEIIARSRA
CEEEEEECCHHHHHHHHHHHHHCCCEEEEECCCCEEEEECCCCCCCCCCCHHHHHHHCCC
AGRITFSTDVAASVAHGEVQFIAVGTPPDEDGSADLQYVLEAARNIGRTMNGFKVVVDKS
CCEEEEECCHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECC
TVPVGTAQRVRAVIEEELAKRGLNGSAQHGFSIVSNPEFLKEGAAVEDFMRPDRIVVGVD
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCHHHHHCCCCHHHHCCCCEEEEECC
NDEQGDKAREKIRRLYAPFNRNHERTLYMDVRSAEFTKYAANAMLATRISFMNEMANLAD
CCCCCHHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TVGADIEAVRRGIGSDPRIGYHFLYAGVGYGGSCFPKDVQALIRTGAEQGHNLRILEAVE
HHCCCHHHHHHCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEHHHH
DVNHEQKEVLVRKITGSLGEDLSGRTFAVWGLSFKPNTDDMREAPSRRVIGQLLARGATV
HCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCHHHHCCHHHHHHHHHHCCCEE
RAYDPVATTEAKRVFALDLAGLPEQQARLHFESTQDETLGGADALVIVTEWKEFKSPDFT
EECCCCCCCCCCEEEEEECCCCCHHHHHEEECCCCCCCCCCCCEEEEEEECHHHCCCCHH
HLKSQLKAPLIFDGRNLYEPEAMSELGIDYHSIGRPYARPAETSSDSGRA
HHHHHCCCCEEECCCCCCCCHHHHHHCCCHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]