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The map label for this gene is czrA [H]

Identifier: 186475488

GI number: 186475488

Start: 815960

End: 816340

Strand: Direct

Name: czrA [H]

Synonym: Bphy_0723

Alternate gene names: 186475488

Gene position: 815960-816340 (Clockwise)

Preceding gene: 186475486

Following gene: 186475489

Centisome position: 23.45

GC content: 63.52

Gene sequence:

>381_bases
ATGTCAATATCGGTCTCGCCGATCGACGTGCCCGAAATGTCAGCCGTTACATCCCTGAATACCGACGTCCGTGTCGTCCA
GCTCGCCGATCTGTTCCGCCTGCTTGGCGATCCGACGCGCCTGCGCATCGTGCTCGCCTGTGTTGACGAACGGCGTGCGG
TCGGCGCGATCGCGGAGTCGCTCAACTTATCGCCGTCGCTCGTGAGCCACCATCTGCGCTTGCTGCGGGCCGCGCGCATC
GTGCGCGCGGAGCGGCAAGGCAAGCAGGTCTTCTACGTCGCCGCCGACGGACACATCAGCGGCATGCTGACCGACATGCT
CGAACACGTCGATGAACCTGTCAGCGACGCTTCCGCCGAATTCACGCAGGATCACGCATGA

Upstream 100 bases:

>100_bases
AGGTGTGATACAGGAAAACCCGCATTTTCCCATACTCGGCGAATCCTTCCCGTGATTGACGTCGGGCGTGTTGTGCAATA
ACATGTGAACACATGTACAT

Downstream 100 bases:

>100_bases
AATACACCGCTCATCAGACGGACAGCGCCTCCGTGACGCATCAACCGAAGGCGCACGTGCACACCGATGCTTGCGACCAC
GCGGGTCACGACGACGCAGA

Product: ArsR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 126; Mature: 125

Protein sequence:

>126_residues
MSISVSPIDVPEMSAVTSLNTDVRVVQLADLFRLLGDPTRLRIVLACVDERRAVGAIAESLNLSPSLVSHHLRLLRAARI
VRAERQGKQVFYVAADGHISGMLTDMLEHVDEPVSDASAEFTQDHA

Sequences:

>Translated_126_residues
MSISVSPIDVPEMSAVTSLNTDVRVVQLADLFRLLGDPTRLRIVLACVDERRAVGAIAESLNLSPSLVSHHLRLLRAARI
VRAERQGKQVFYVAADGHISGMLTDMLEHVDEPVSDASAEFTQDHA
>Mature_125_residues
SISVSPIDVPEMSAVTSLNTDVRVVQLADLFRLLGDPTRLRIVLACVDERRAVGAIAESLNLSPSLVSHHLRLLRAARIV
RAERQGKQVFYVAADGHISGMLTDMLEHVDEPVSDASAEFTQDHA

Specific function: Metal-responsive transcriptional regulator that represses transcription of cadA and the czcD-trkA operon by binding specifically to their promoter. Binding of zinc causes the repressor to dissociate from the DNA [H]

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 13758; Mature: 13627

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSISVSPIDVPEMSAVTSLNTDVRVVQLADLFRLLGDPTRLRIVLACVDERRAVGAIAES
CCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHCCCHHHEEHEEEHHHHHHHHHHHHH
LNLSPSLVSHHLRLLRAARIVRAERQGKQVFYVAADGHISGMLTDMLEHVDEPVSDASAE
CCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHCCCCCCCCCH
FTQDHA
HHCCCC
>Mature Secondary Structure 
SISVSPIDVPEMSAVTSLNTDVRVVQLADLFRLLGDPTRLRIVLACVDERRAVGAIAES
CCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHCCCHHHEEHEEEHHHHHHHHHHHHH
LNLSPSLVSHHLRLLRAARIVRAERQGKQVFYVAADGHISGMLTDMLEHVDEPVSDASAE
CCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHCCCCCCCCCH
FTQDHA
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]