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The map label for this gene is add [H]

Identifier: 186475475

GI number: 186475475

Start: 796999

End: 798039

Strand: Reverse

Name: add [H]

Synonym: Bphy_0710

Alternate gene names: 186475475

Gene position: 798039-796999 (Counterclockwise)

Preceding gene: 186475476

Following gene: 186475474

Centisome position: 22.94

GC content: 62.73

Gene sequence:

>1041_bases
ATGACGACAACCACACTGTCCCCGCTAGCTCGCAAAACCAGCCTCGCACCGAAGGCCGAGTTGCACATTCATATCGAAGG
TTCGCTGGAACCCGAGCTGATCTTCAAGCTTGCCGAACGCAACGGCGTGAAACTCGCGTACGAATCGATCGATGCGCTGC
GTGCCGCGTATGCGTTCACCGATCTGCAGTCGTTCCTCGACATCTACTACGCGGGCGCCAGCGTGCTGCTGAAGGAAGAG
GACTTCTACGACATGACGATGGCTTACGTCGAGCGCGCGCTCGCGGACAACGTCGTGCATACGGAAATCTTCTTCGATCC
GCAGACGCATACGGAGCGCGGCGTGCCGATTGCGACCGTGGTCGCGGGCATCGAGCGCGCACTTGCCGAAGCGCAAACGC
GCGGTCTCACGAGCAAACTGATCTTGTGTTTCCTGCGGCATCTGTCCGAAGACGATGCACTCGCGACGTTCGACGCGGCG
CTGCCGCTGTTCGATCAGTACAGGCACCGGCTGATCGGTGTCGGGCTCGATTCGTCGGAGCACGGCCATCCGCCGTCCAA
GTTCGAGCGCGTGTTCGCGAAGGCACGCGCCAAAGGTCTGAAGCTCGTCGCACATGCCGGCGAAGAAGGCCCGCCGTCGT
ACATCTACGAAGCGCTCGATCTGCTGAAGGTCGACCGCGTCGACCACGGCGTGCGCAGCATCGAAGACCCGGCGCTCGTC
ACGCGCCTTGCCGATTCGCGTGTCGCTCTGACGGTCTGCCCGCTGTCGAACCTGAAGCTGTGCGTGTTCGACGATCTGAC
GAGGCATACGCTGAAGGCGCTGCTCGACGCGGGCGTCGCCGTCACCGTGAACTCCGACGACCCCGCGTACTTCGGCGGCT
ACGTCAACGAAAACTACCTCGCGACGATCGACGCCCTCAAGCTCGACGACGCCGAGGTGTACACGATCATCCGCAACGGC
TTCGAGGCGTCGTTCGTCACGCCCGCGCAGCGCGATGCGATGATCGCGAAACTCGATGCGCACTGGCGCGCATCTGCCTG
A

Upstream 100 bases:

>100_bases
CAAACCAGTATCGAGCATGTATTGCAATCACATTGGGGACGACCGACCCAGCCATCGGACGTCGAATCAATCCATCGATA
ACCCGAATCACTGACCGACC

Downstream 100 bases:

>100_bases
TTCTTACCCGTTCGGAGACGGTTTCACTCATGACTCAAACAGCTTTTCGCGCGCACCTGCTGACGTTCAACGGCGATCCT
GCGCAATCGTCCAACGCTGC

Product: adenosine deaminase

Products: NA

Alternate protein names: Adenosine aminohydrolase [H]

Number of amino acids: Translated: 346; Mature: 345

Protein sequence:

>346_residues
MTTTTLSPLARKTSLAPKAELHIHIEGSLEPELIFKLAERNGVKLAYESIDALRAAYAFTDLQSFLDIYYAGASVLLKEE
DFYDMTMAYVERALADNVVHTEIFFDPQTHTERGVPIATVVAGIERALAEAQTRGLTSKLILCFLRHLSEDDALATFDAA
LPLFDQYRHRLIGVGLDSSEHGHPPSKFERVFAKARAKGLKLVAHAGEEGPPSYIYEALDLLKVDRVDHGVRSIEDPALV
TRLADSRVALTVCPLSNLKLCVFDDLTRHTLKALLDAGVAVTVNSDDPAYFGGYVNENYLATIDALKLDDAEVYTIIRNG
FEASFVTPAQRDAMIAKLDAHWRASA

Sequences:

>Translated_346_residues
MTTTTLSPLARKTSLAPKAELHIHIEGSLEPELIFKLAERNGVKLAYESIDALRAAYAFTDLQSFLDIYYAGASVLLKEE
DFYDMTMAYVERALADNVVHTEIFFDPQTHTERGVPIATVVAGIERALAEAQTRGLTSKLILCFLRHLSEDDALATFDAA
LPLFDQYRHRLIGVGLDSSEHGHPPSKFERVFAKARAKGLKLVAHAGEEGPPSYIYEALDLLKVDRVDHGVRSIEDPALV
TRLADSRVALTVCPLSNLKLCVFDDLTRHTLKALLDAGVAVTVNSDDPAYFGGYVNENYLATIDALKLDDAEVYTIIRNG
FEASFVTPAQRDAMIAKLDAHWRASA
>Mature_345_residues
TTTTLSPLARKTSLAPKAELHIHIEGSLEPELIFKLAERNGVKLAYESIDALRAAYAFTDLQSFLDIYYAGASVLLKEED
FYDMTMAYVERALADNVVHTEIFFDPQTHTERGVPIATVVAGIERALAEAQTRGLTSKLILCFLRHLSEDDALATFDAAL
PLFDQYRHRLIGVGLDSSEHGHPPSKFERVFAKARAKGLKLVAHAGEEGPPSYIYEALDLLKVDRVDHGVRSIEDPALVT
RLADSRVALTVCPLSNLKLCVFDDLTRHTLKALLDAGVAVTVNSDDPAYFGGYVNENYLATIDALKLDDAEVYTIIRNGF
EASFVTPAQRDAMIAKLDAHWRASA

Specific function: Unknown

COG id: COG1816

COG function: function code F; Adenosine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenosine and AMP deaminases family [H]

Homologues:

Organism=Homo sapiens, GI47078295, Length=342, Percent_Identity=24.5614035087719, Blast_Score=103, Evalue=3e-22,
Organism=Escherichia coli, GI1787910, Length=330, Percent_Identity=27.8787878787879, Blast_Score=131, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI32565969, Length=349, Percent_Identity=21.4899713467049, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17538512, Length=349, Percent_Identity=21.4899713467049, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6324188, Length=331, Percent_Identity=41.9939577039275, Blast_Score=270, Evalue=2e-73,
Organism=Drosophila melanogaster, GI24645260, Length=324, Percent_Identity=24.0740740740741, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001365
- InterPro:   IPR006330 [H]

Pfam domain/function: PF00962 A_deaminase [H]

EC number: =3.5.4.4 [H]

Molecular weight: Translated: 38136; Mature: 38005

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTTLSPLARKTSLAPKAELHIHIEGSLEPELIFKLAERNGVKLAYESIDALRAAYAFT
CCCCCCCHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHCCCCEEHHHHHHHHHHHHHHH
DLQSFLDIYYAGASVLLKEEDFYDMTMAYVERALADNVVHTEIFFDPQTHTERGVPIATV
HHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCHHHHH
VAGIERALAEAQTRGLTSKLILCFLRHLSEDDALATFDAALPLFDQYRHRLIGVGLDSSE
HHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHEEECCCCCCC
HGHPPSKFERVFAKARAKGLKLVAHAGEEGPPSYIYEALDLLKVDRVDHGVRSIEDPALV
CCCCHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
TRLADSRVALTVCPLSNLKLCVFDDLTRHTLKALLDAGVAVTVNSDDPAYFGGYVNENYL
HHHCCCCEEEEEECCCCCEEEEEHHHHHHHHHHHHHCCEEEEECCCCCCEECCCCCCCEE
ATIDALKLDDAEVYTIIRNGFEASFVTPAQRDAMIAKLDAHWRASA
EEEEEEECCCHHHHHHHHCCCCCCCCCCCHHCHHEEEECCCCCCCC
>Mature Secondary Structure 
TTTTLSPLARKTSLAPKAELHIHIEGSLEPELIFKLAERNGVKLAYESIDALRAAYAFT
CCCCCCHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHCCCCEEHHHHHHHHHHHHHHH
DLQSFLDIYYAGASVLLKEEDFYDMTMAYVERALADNVVHTEIFFDPQTHTERGVPIATV
HHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCHHHHH
VAGIERALAEAQTRGLTSKLILCFLRHLSEDDALATFDAALPLFDQYRHRLIGVGLDSSE
HHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHEEECCCCCCC
HGHPPSKFERVFAKARAKGLKLVAHAGEEGPPSYIYEALDLLKVDRVDHGVRSIEDPALV
CCCCHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
TRLADSRVALTVCPLSNLKLCVFDDLTRHTLKALLDAGVAVTVNSDDPAYFGGYVNENYL
HHHCCCCEEEEEECCCCCEEEEEHHHHHHHHHHHHHCCEEEEECCCCCCEECCCCCCCEE
ATIDALKLDDAEVYTIIRNGFEASFVTPAQRDAMIAKLDAHWRASA
EEEEEEECCCHHHHHHHHCCCCCCCCCCCHHCHHEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA