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The map label for this gene is gltC [H]

Identifier: 186475447

GI number: 186475447

Start: 766231

End: 767175

Strand: Reverse

Name: gltC [H]

Synonym: Bphy_0682

Alternate gene names: 186475447

Gene position: 767175-766231 (Counterclockwise)

Preceding gene: 186475450

Following gene: 186475445

Centisome position: 22.05

GC content: 65.5

Gene sequence:

>945_bases
ATGCGCATCTCGTTGCGGCTTCTGCGTTACTTCACGGCGGCGGCCGAAACGGGGAGCACGACGGCGGCGGCAAGACAGCT
GAACGTGTCGCAGCCGTCCATATCCGTCGCCATTCGCGAACTCGAAGCACTGTTCGATGACACGCTGTTCACTCGCGAGT
CGGGCGCGAAGATGACCTTGACGCGTTTCGGCGTTCGCAAGCTCGCGGAGGCGCATCAATTGCTGAGGGCAGCCGCATCG
TTCGAAGCCGATGACGGCGGCGACGCCGCCGCCGGCGAAGTGCAGATCGGCGTGTTCAGCACCATTGCGCCCGTCTATCT
GCCCGTGCTGCTGCGCATCGCGAGCGAGCGCTTCTGCGATCTGTCGGTCCGCTTCATCGAAGGCGACCTGATGCAGCTCG
AAGACGCGCTGCGCAGCAGCCGCATCGAACTCGCGCTGATGTACGACGTCGGCCTGCCCGCCGATATCGAGCGCGAATGT
CTCGCGGAACTCCGCCCCTACGCGCTGGTGCCTGCGGCGTCGAAGCTCGCGAAGAAGACGGGCAAGCTGTCGCTGCATGA
TCTCGCGAAAGAGCCGCTGATCCTGATCGATCTGCCGCATAGCCGCGAGTTTCTGATGGCGCCGTTCTGGCAATGCGGAC
TCGCGCCCGAGGTGCGTTATCGAGCGACTTCGCTAGAACTCGTGCGCGGCATGGTGGCGAACGGTCTCGGCGTGTCGCTG
CTGATCACGCAGGGTAAAGCGGGCGCGGAGCCAGCTGCGATCGAGCGCCCCATTCGTGAAGAGACCATCCGCCAGCCGCT
GGTAATTGCACGTCCCGCGCGCGCGTCCCGCACCAAAGCGGCGGAACTCGTCGCGCAGTGCATGCGCGACGCCGTCAATG
AAGCGATGGCGAAAGGCGCCGGCAGAGCCGCTCGCACGCGCCGTCGTGGGACGCGGACCGACTAG

Upstream 100 bases:

>100_bases
CTTGCATCGAACACTCCTTTCATCAGGGATGCGCCGATTCTGGGCGCCACAGCCTATCAAGTAAAATATGGAATTTAGTT
ACCACCTATAGGTTTTTCTG

Downstream 100 bases:

>100_bases
CGCGCGTTAGCGATGCCACCCATCGAGCGTCGTGGGCTGCAAGCAGGTTCGACAGCAGCAGGCCATCGGCATAGACGAGA
CCGCGTGCACTCTGCAGTTC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MRISLRLLRYFTAAAETGSTTAAARQLNVSQPSISVAIRELEALFDDTLFTRESGAKMTLTRFGVRKLAEAHQLLRAAAS
FEADDGGDAAAGEVQIGVFSTIAPVYLPVLLRIASERFCDLSVRFIEGDLMQLEDALRSSRIELALMYDVGLPADIEREC
LAELRPYALVPAASKLAKKTGKLSLHDLAKEPLILIDLPHSREFLMAPFWQCGLAPEVRYRATSLELVRGMVANGLGVSL
LITQGKAGAEPAAIERPIREETIRQPLVIARPARASRTKAAELVAQCMRDAVNEAMAKGAGRAARTRRRGTRTD

Sequences:

>Translated_314_residues
MRISLRLLRYFTAAAETGSTTAAARQLNVSQPSISVAIRELEALFDDTLFTRESGAKMTLTRFGVRKLAEAHQLLRAAAS
FEADDGGDAAAGEVQIGVFSTIAPVYLPVLLRIASERFCDLSVRFIEGDLMQLEDALRSSRIELALMYDVGLPADIEREC
LAELRPYALVPAASKLAKKTGKLSLHDLAKEPLILIDLPHSREFLMAPFWQCGLAPEVRYRATSLELVRGMVANGLGVSL
LITQGKAGAEPAAIERPIREETIRQPLVIARPARASRTKAAELVAQCMRDAVNEAMAKGAGRAARTRRRGTRTD
>Mature_314_residues
MRISLRLLRYFTAAAETGSTTAAARQLNVSQPSISVAIRELEALFDDTLFTRESGAKMTLTRFGVRKLAEAHQLLRAAAS
FEADDGGDAAAGEVQIGVFSTIAPVYLPVLLRIASERFCDLSVRFIEGDLMQLEDALRSSRIELALMYDVGLPADIEREC
LAELRPYALVPAASKLAKKTGKLSLHDLAKEPLILIDLPHSREFLMAPFWQCGLAPEVRYRATSLELVRGMVANGLGVSL
LITQGKAGAEPAAIERPIREETIRQPLVIARPARASRTKAAELVAQCMRDAVNEAMAKGAGRAARTRRRGTRTD

Specific function: Positive regulator of glutamate biosynthesis (gltAB genes). Negatively regulates its own expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=246, Percent_Identity=28.8617886178862, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787879, Length=300, Percent_Identity=28.6666666666667, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI145693105, Length=291, Percent_Identity=25.4295532646048, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34242; Mature: 34242

Theoretical pI: Translated: 9.22; Mature: 9.22

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRISLRLLRYFTAAAETGSTTAAARQLNVSQPSISVAIRELEALFDDTLFTRESGAKMTL
CCHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEHH
TRFGVRKLAEAHQLLRAAASFEADDGGDAAAGEVQIGVFSTIAPVYLPVLLRIASERFCD
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHC
LSVRFIEGDLMQLEDALRSSRIELALMYDVGLPADIERECLAELRPYALVPAASKLAKKT
CEEEEHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCHHHHHHCCCCEECHHHHHHHHHH
GKLSLHDLAKEPLILIDLPHSREFLMAPFWQCGLAPEVRYRATSLELVRGMVANGLGVSL
CCCCHHHHCCCCEEEEECCCCCCHHHCCHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEE
LITQGKAGAEPAAIERPIREETIRQPLVIARPARASRTKAAELVAQCMRDAVNEAMAKGA
EEECCCCCCCCHHHHCCHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
GRAARTRRRGTRTD
CHHHHHHCCCCCCC
>Mature Secondary Structure
MRISLRLLRYFTAAAETGSTTAAARQLNVSQPSISVAIRELEALFDDTLFTRESGAKMTL
CCHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEHH
TRFGVRKLAEAHQLLRAAASFEADDGGDAAAGEVQIGVFSTIAPVYLPVLLRIASERFCD
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHC
LSVRFIEGDLMQLEDALRSSRIELALMYDVGLPADIERECLAELRPYALVPAASKLAKKT
CEEEEHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCHHHHHHCCCCEECHHHHHHHHHH
GKLSLHDLAKEPLILIDLPHSREFLMAPFWQCGLAPEVRYRATSLELVRGMVANGLGVSL
CCCCHHHHCCCCEEEEECCCCCCHHHCCHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEE
LITQGKAGAEPAAIERPIREETIRQPLVIARPARASRTKAAELVAQCMRDAVNEAMAKGA
EEECCCCCCCCHHHHCCHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
GRAARTRRRGTRTD
CHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2548995; 9384377 [H]