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The map label for this gene is lolA [H]

Identifier: 186475402

GI number: 186475402

Start: 716618

End: 717313

Strand: Direct

Name: lolA [H]

Synonym: Bphy_0636

Alternate gene names: 186475402

Gene position: 716618-717313 (Clockwise)

Preceding gene: 186475401

Following gene: 186475404

Centisome position: 20.6

GC content: 60.06

Gene sequence:

>696_bases
ATGCTGCAAACCATTGGGTCTAAGACCCGTCTTGGCAATCTGATGCGCGCGCTCGCTTTCGGCGCATCGATGCTCATCAC
TTCGCATGCGTTCGCGAGCGGCACTGAGCAACTCAAGCAATTCGTGTCGCAAGTGCGTTCCGCGCGCGGCGAGTTCGTGC
AGACGGAAGTGCGGGCGCCGAGTAACGCGCAGCAACAGGCGAGCGGCGTGCTATCGACGCAAAACGCGTCGCAGAACAAG
GTGTCGAGTGGCTCGTTTACGTTCGCGCGGCCGGGCAAGTTCATCTGGGCGTACGAAAAGCCGTATGCACAGCTGCTACA
GGCCGACGGCGACAAGCTCTACGTGTACGACAAGGATCTGAACCAGGTGACGGTGCGCAAGCTTGGCGGCGCGCTCGGCG
CGAGCCCGGCCGCAATCCTGTTCGGCAGCAACGATCTCGACAAGAATTTCACGCTGAAGGACGCGGGCGTGAAGGCGGGC
ATCGACTGGCTCGAACTCATTCCGAAGTCGAAGGACACGCAGTTTCAGCGCGTCGGCATCGGCTTCAAGGAGGGCAACCT
CGAAGCAATGGAACTTCACGATGTGTTCGGCAACGTGACGTTGCTGAAATTCTCCAACATCCAGAAGAATCCGTCGCTGC
CCGCCGACGCGTTCAAGTTCACGGTGCCGAAGGGCGCCGATGTGATCAACGGCTAA

Upstream 100 bases:

>100_bases
GGTGTCCGCAATGTCGTCGAACGGCAACCGCGAGATTTTGGTGCCGGCGCGCGAGACGGATTGACGTTCGCTGCCCGAGC
GCTACAAGGGAGAAAACCAC

Downstream 100 bases:

>100_bases
ATGCCTGTCACGCCTGAAGGCCGGGCGACGGATGCGCGGCCTTCATATCGTCGATAAACGCATCGACGATTTCCGTCCGA
TGCTGCCGCGTGCGCGTGAC

Product: outer-membrane lipoprotein carrier protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MLQTIGSKTRLGNLMRALAFGASMLITSHAFASGTEQLKQFVSQVRSARGEFVQTEVRAPSNAQQQASGVLSTQNASQNK
VSSGSFTFARPGKFIWAYEKPYAQLLQADGDKLYVYDKDLNQVTVRKLGGALGASPAAILFGSNDLDKNFTLKDAGVKAG
IDWLELIPKSKDTQFQRVGIGFKEGNLEAMELHDVFGNVTLLKFSNIQKNPSLPADAFKFTVPKGADVING

Sequences:

>Translated_231_residues
MLQTIGSKTRLGNLMRALAFGASMLITSHAFASGTEQLKQFVSQVRSARGEFVQTEVRAPSNAQQQASGVLSTQNASQNK
VSSGSFTFARPGKFIWAYEKPYAQLLQADGDKLYVYDKDLNQVTVRKLGGALGASPAAILFGSNDLDKNFTLKDAGVKAG
IDWLELIPKSKDTQFQRVGIGFKEGNLEAMELHDVFGNVTLLKFSNIQKNPSLPADAFKFTVPKGADVING
>Mature_231_residues
MLQTIGSKTRLGNLMRALAFGASMLITSHAFASGTEQLKQFVSQVRSARGEFVQTEVRAPSNAQQQASGVLSTQNASQNK
VSSGSFTFARPGKFIWAYEKPYAQLLQADGDKLYVYDKDLNQVTVRKLGGALGASPAAILFGSNDLDKNFTLKDAGVKAG
IDWLELIPKSKDTQFQRVGIGFKEGNLEAMELHDVFGNVTLLKFSNIQKNPSLPADAFKFTVPKGADVING

Specific function: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the l

COG id: COG2834

COG function: function code M; Outer membrane lipoprotein-sorting protein

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lolA family [H]

Homologues:

None

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004564
- InterPro:   IPR018323 [H]

Pfam domain/function: PF03548 LolA [H]

EC number: NA

Molecular weight: Translated: 25010; Mature: 25010

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQTIGSKTRLGNLMRALAFGASMLITSHAFASGTEQLKQFVSQVRSARGEFVQTEVRAP
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEHHCCCC
SNAQQQASGVLSTQNASQNKVSSGSFTFARPGKFIWAYEKPYAQLLQADGDKLYVYDKDL
CCHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCEEEEECCHHHHHHHCCCCEEEEEECCC
NQVTVRKLGGALGASPAAILFGSNDLDKNFTLKDAGVKAGIDWLELIPKSKDTQFQRVGI
CHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEECCCCCCCCHHHHHCCCCCCCCCHHCCC
GFKEGNLEAMELHDVFGNVTLLKFSNIQKNPSLPADAFKFTVPKGADVING
CCCCCCEEHEEHHHHHCCEEEEEECCCCCCCCCCCCCEEEECCCCCCCCCC
>Mature Secondary Structure
MLQTIGSKTRLGNLMRALAFGASMLITSHAFASGTEQLKQFVSQVRSARGEFVQTEVRAP
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEHHCCCC
SNAQQQASGVLSTQNASQNKVSSGSFTFARPGKFIWAYEKPYAQLLQADGDKLYVYDKDL
CCHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCEEEEECCHHHHHHHCCCCEEEEEECCC
NQVTVRKLGGALGASPAAILFGSNDLDKNFTLKDAGVKAGIDWLELIPKSKDTQFQRVGI
CHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEECCCCCCCCHHHHHCCCCCCCCCHHCCC
GFKEGNLEAMELHDVFGNVTLLKFSNIQKNPSLPADAFKFTVPKGADVING
CCCCCCEEHEEHHHHHCCEEEEEECCCCCCCCCCCCCEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA