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The map label for this gene is ftsK2 [H]

Identifier: 186475401

GI number: 186475401

Start: 714314

End: 716581

Strand: Direct

Name: ftsK2 [H]

Synonym: Bphy_0635

Alternate gene names: 186475401

Gene position: 714314-716581 (Clockwise)

Preceding gene: 186475397

Following gene: 186475402

Centisome position: 20.53

GC content: 63.76

Gene sequence:

>2268_bases
ATGTCGCGCCTTTTCACCGAAATCCGCTGGATTCTCCAGGTGGCGTTAGGCGTCTTCCTCGTGATGGCGCTGATCAGCTA
CAGCCGCCGCGACCCAAGCTGGACGCACGCGGCGGCCGTCGATCACATCTCGAACTGGGCCGGACGCGTCGGCGCCTGGA
CCTCGGACATCCTCCTTCTGCTCTTCGGCCTGTCCGCCTGGTGGTGGATCGTGCTGCTCGCGCGCCGCATTTCTGCGAAC
TACAGGCGCATCACGCGTCAGGAAGAGCCCGCCGAAGACACGCCGCGCGACAATAGCTGGCTCGCCGACGTGTTCGCGTT
CGTGCTGGTGCTGCTCGCATGCGACGGCATCGAGGCGCTGCGCATGTGGTCGCTGAAAGTGCAGTTGCCGCGCGCGCCGG
GCGGCGTGATCGGCGAGGCGGTGGCGAAGGGCGTCTCGCACGCGCTCGGTTTCACGGGCGGCACGCTGGCGCTGCTGATC
GCGCTTGGCATCGGGCTGTCGCTTTATTTCCGTTTCTCGTGGCTCTCGGTGTGCGAGAGGGTCGGCGATTCGATCATCAA
TGCCGTTACGCTCGCCAAGCTGCGCCGCGAGGCAGGCCGCGACCGCAAGCTCGGCGAAGCCGCCGCCGTGAAGCGCGAAG
GCAAGGTTGAACAGAACCGCGTGAAGATCGAGGAGCACGAGCCGGTGATAATCGTCCCGCCCGTGACGAAGCCGGAGAAG
TCCGAACGCGTCGAGAAAGAACGCCAGGTGCCGCTGTTCGAGAGCCTGCCCGGCGATTCCACGTTGCCCGCGATCTCGCT
GCTCGATGCCGCCCCCGCCACCCAGGAAACCATCTCCGCCGATACGCTCGAATTCACCTCGCGACTCATTGAGAAGAAGC
TGAAGGATTTCGGCGTCGATGTGAGCGTAGTTGCAGCGTATCCTGGTCCGGTCGTCACGCGTTACGAAATCGAACCGGCG
GTCGGCGTGAAGGGCAGTCAGATCGTGAACCTGGCGAAGGACCTGGCGCGCTCGCTGTCGCTGACGTCGATCCGCGTCGT
CGAAACGATTCCGGGCAAGAATTTCATGGCGCTCGAACTGCCGAACCAACGTCGTCAGACGGTGCGGCTGTCGGAGATTC
TCGGCTCGGCCGTCTACGCCGACGCCGGGTCGCCGCTGACGATGGGTCTCGGCAAGGACATCGGCGGCAAGCCGGTGTGC
GCGGACCTCGCAAAAATGCCGCACTTGCTGGTTGCGGGCACGACGGGCTCGGGCAAGTCGGTCGGTATCAACGCGATGAT
TCTCTCGCTCTTGTACAAGGCGAGCGCGGACCAGGTGCGAATGATCCTGATCGATCCGAAGATGCTCGAAATGAGCGTCT
ACGAGGGCATTCCGCATCTGCTGTGTCCTGTCGTCACGGACATGCGCCAGGCCGGTCACGCGCTGAACTGGACCGTCGCC
GAAATGGAGCGCCGCTACAAGCTGATGAGCAAGCTTGGCGTGCGGAACCTCGCGGGTTTCAACAATAAGATCGACGAAGC
GGCGAAGCGCGAAGAGAAGCTTCCGAATCCGTTCAGCCTGACACCGGACGATCCTGAACCGCTGTCGCGTCTTCCGAATA
TCGTCGTCGTGATCGACGAATTGGCCGACCTGATGATGGTGGTCGGCAAGAAGGTTGAAGAACTGATCGCACGAATCGCA
CAGAAGGCGCGCGCGGCGGGCATCCATCTGATTCTCGCGACGCAGCGTCCGTCGGTCGACGTGATCACCGGCCTCATCAA
GGCCAACGTGCCGACGCGGATGGCGTTCCAGGTGTCGTCGAAGATCGACTCGCGCACTATCCTCGACCAGCAAGGCGCGG
AATCGCTGCTCGGCATGGGCGACATGCTGTATCTGCCGCCTGGTTCGGGTCTGCCCGTCCGGGTGCACGGCGCGTTCGTG
TCCGACGACGAGGTGCATCGCGTGGTCGAGAAGCTCAAGGAGCAGGGCGAGCCGAACTACATCGAAGGGCTGCTGGAAGG
CGGCGTATCGGGTGAAGGCGACGAAGGTTCCGCAGAGGGGGCGGGAACCGGAGCGGGCGGCACCGAGTCCGACCCTCTAT
ACGATCAGGCCGTCGAAATCGTCGTCAAGAATCGCCGCGCGTCGATCTCGCTCGTGCAGCGGCATCTGCGCATCGGCTAC
AACCGCGCCGCACGTCTGCTCGAACAGATGGAGCAGTCGGGGCTGGTGTCCGCAATGTCGTCGAACGGCAACCGCGAGAT
TTTGGTGCCGGCGCGCGAGACGGATTGA

Upstream 100 bases:

>100_bases
AACAGAAGCCGGCACCCCAAACCGCTGCAGGCCGCCACACGCAACAGGCTCAATGGCAAAAGCTCCATACTCCGCGAACG
CGCAGGCATTGCCTCACCGC

Downstream 100 bases:

>100_bases
CGTTCGCTGCCCGAGCGCTACAAGGGAGAAAACCACATGCTGCAAACCATTGGGTCTAAGACCCGTCTTGGCAATCTGAT
GCGCGCGCTCGCTTTCGGCG

Product: cell division FtsK/SpoIIIE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 755; Mature: 754

Protein sequence:

>755_residues
MSRLFTEIRWILQVALGVFLVMALISYSRRDPSWTHAAAVDHISNWAGRVGAWTSDILLLLFGLSAWWWIVLLARRISAN
YRRITRQEEPAEDTPRDNSWLADVFAFVLVLLACDGIEALRMWSLKVQLPRAPGGVIGEAVAKGVSHALGFTGGTLALLI
ALGIGLSLYFRFSWLSVCERVGDSIINAVTLAKLRREAGRDRKLGEAAAVKREGKVEQNRVKIEEHEPVIIVPPVTKPEK
SERVEKERQVPLFESLPGDSTLPAISLLDAAPATQETISADTLEFTSRLIEKKLKDFGVDVSVVAAYPGPVVTRYEIEPA
VGVKGSQIVNLAKDLARSLSLTSIRVVETIPGKNFMALELPNQRRQTVRLSEILGSAVYADAGSPLTMGLGKDIGGKPVC
ADLAKMPHLLVAGTTGSGKSVGINAMILSLLYKASADQVRMILIDPKMLEMSVYEGIPHLLCPVVTDMRQAGHALNWTVA
EMERRYKLMSKLGVRNLAGFNNKIDEAAKREEKLPNPFSLTPDDPEPLSRLPNIVVVIDELADLMMVVGKKVEELIARIA
QKARAAGIHLILATQRPSVDVITGLIKANVPTRMAFQVSSKIDSRTILDQQGAESLLGMGDMLYLPPGSGLPVRVHGAFV
SDDEVHRVVEKLKEQGEPNYIEGLLEGGVSGEGDEGSAEGAGTGAGGTESDPLYDQAVEIVVKNRRASISLVQRHLRIGY
NRAARLLEQMEQSGLVSAMSSNGNREILVPARETD

Sequences:

>Translated_755_residues
MSRLFTEIRWILQVALGVFLVMALISYSRRDPSWTHAAAVDHISNWAGRVGAWTSDILLLLFGLSAWWWIVLLARRISAN
YRRITRQEEPAEDTPRDNSWLADVFAFVLVLLACDGIEALRMWSLKVQLPRAPGGVIGEAVAKGVSHALGFTGGTLALLI
ALGIGLSLYFRFSWLSVCERVGDSIINAVTLAKLRREAGRDRKLGEAAAVKREGKVEQNRVKIEEHEPVIIVPPVTKPEK
SERVEKERQVPLFESLPGDSTLPAISLLDAAPATQETISADTLEFTSRLIEKKLKDFGVDVSVVAAYPGPVVTRYEIEPA
VGVKGSQIVNLAKDLARSLSLTSIRVVETIPGKNFMALELPNQRRQTVRLSEILGSAVYADAGSPLTMGLGKDIGGKPVC
ADLAKMPHLLVAGTTGSGKSVGINAMILSLLYKASADQVRMILIDPKMLEMSVYEGIPHLLCPVVTDMRQAGHALNWTVA
EMERRYKLMSKLGVRNLAGFNNKIDEAAKREEKLPNPFSLTPDDPEPLSRLPNIVVVIDELADLMMVVGKKVEELIARIA
QKARAAGIHLILATQRPSVDVITGLIKANVPTRMAFQVSSKIDSRTILDQQGAESLLGMGDMLYLPPGSGLPVRVHGAFV
SDDEVHRVVEKLKEQGEPNYIEGLLEGGVSGEGDEGSAEGAGTGAGGTESDPLYDQAVEIVVKNRRASISLVQRHLRIGY
NRAARLLEQMEQSGLVSAMSSNGNREILVPARETD
>Mature_754_residues
SRLFTEIRWILQVALGVFLVMALISYSRRDPSWTHAAAVDHISNWAGRVGAWTSDILLLLFGLSAWWWIVLLARRISANY
RRITRQEEPAEDTPRDNSWLADVFAFVLVLLACDGIEALRMWSLKVQLPRAPGGVIGEAVAKGVSHALGFTGGTLALLIA
LGIGLSLYFRFSWLSVCERVGDSIINAVTLAKLRREAGRDRKLGEAAAVKREGKVEQNRVKIEEHEPVIIVPPVTKPEKS
ERVEKERQVPLFESLPGDSTLPAISLLDAAPATQETISADTLEFTSRLIEKKLKDFGVDVSVVAAYPGPVVTRYEIEPAV
GVKGSQIVNLAKDLARSLSLTSIRVVETIPGKNFMALELPNQRRQTVRLSEILGSAVYADAGSPLTMGLGKDIGGKPVCA
DLAKMPHLLVAGTTGSGKSVGINAMILSLLYKASADQVRMILIDPKMLEMSVYEGIPHLLCPVVTDMRQAGHALNWTVAE
MERRYKLMSKLGVRNLAGFNNKIDEAAKREEKLPNPFSLTPDDPEPLSRLPNIVVVIDELADLMMVVGKKVEELIARIAQ
KARAAGIHLILATQRPSVDVITGLIKANVPTRMAFQVSSKIDSRTILDQQGAESLLGMGDMLYLPPGSGLPVRVHGAFVS
DDEVHRVVEKLKEQGEPNYIEGLLEGGVSGEGDEGSAEGAGTGAGGTESDPLYDQAVEIVVKNRRASISLVQRHLRIGYN
RAARLLEQMEQSGLVSAMSSNGNREILVPARETD

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=496, Percent_Identity=62.9032258064516, Blast_Score=607, Evalue=1e-175,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 82181; Mature: 82050

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRLFTEIRWILQVALGVFLVMALISYSRRDPSWTHAAAVDHISNWAGRVGAWTSDILLL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHH
LFGLSAWWWIVLLARRISANYRRITRQEEPAEDTPRDNSWLADVFAFVLVLLACDGIEAL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHH
RMWSLKVQLPRAPGGVIGEAVAKGVSHALGFTGGTLALLIALGIGLSLYFRFSWLSVCER
HHEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGDSIINAVTLAKLRREAGRDRKLGEAAAVKREGKVEQNRVKIEEHEPVIIVPPVTKPEK
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHCEEEECCCCEEEECCCCCCCH
SERVEKERQVPLFESLPGDSTLPAISLLDAAPATQETISADTLEFTSRLIEKKLKDFGVD
HHHHHHHHCCCHHHCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
VSVVAAYPGPVVTRYEIEPAVGVKGSQIVNLAKDLARSLSLTSIRVVETIPGKNFMALEL
EEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCHHEEEEEEECCCCCEEEEEC
PNQRRQTVRLSEILGSAVYADAGSPLTMGLGKDIGGKPVCADLAKMPHLLVAGTTGSGKS
CCHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCHHHHHHHCCCEEEEECCCCCCC
VGINAMILSLLYKASADQVRMILIDPKMLEMSVYEGIPHLLCPVVTDMRQAGHALNWTVA
CHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHH
EMERRYKLMSKLGVRNLAGFNNKIDEAAKREEKLPNPFSLTPDDPEPLSRLPNIVVVIDE
HHHHHHHHHHHHCHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCCEEEEHHH
LADLMMVVGKKVEELIARIAQKARAAGIHLILATQRPSVDVITGLIKANVPTRMAFQVSS
HHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHH
KIDSRTILDQQGAESLLGMGDMLYLPPGSGLPVRVHGAFVSDDEVHRVVEKLKEQGEPNY
CCCHHHHHHHCCHHHHHCCCCEEEECCCCCCEEEEEEEECCCHHHHHHHHHHHHCCCCHH
IEGLLEGGVSGEGDEGSAEGAGTGAGGTESDPLYDQAVEIVVKNRRASISLVQRHLRIGY
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCH
NRAARLLEQMEQSGLVSAMSSNGNREILVPARETD
HHHHHHHHHHHHCCHHHHHHCCCCEEEEECCCCCC
>Mature Secondary Structure 
SRLFTEIRWILQVALGVFLVMALISYSRRDPSWTHAAAVDHISNWAGRVGAWTSDILLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHH
LFGLSAWWWIVLLARRISANYRRITRQEEPAEDTPRDNSWLADVFAFVLVLLACDGIEAL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHH
RMWSLKVQLPRAPGGVIGEAVAKGVSHALGFTGGTLALLIALGIGLSLYFRFSWLSVCER
HHEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGDSIINAVTLAKLRREAGRDRKLGEAAAVKREGKVEQNRVKIEEHEPVIIVPPVTKPEK
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHCEEEECCCCEEEECCCCCCCH
SERVEKERQVPLFESLPGDSTLPAISLLDAAPATQETISADTLEFTSRLIEKKLKDFGVD
HHHHHHHHCCCHHHCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
VSVVAAYPGPVVTRYEIEPAVGVKGSQIVNLAKDLARSLSLTSIRVVETIPGKNFMALEL
EEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCHHEEEEEEECCCCCEEEEEC
PNQRRQTVRLSEILGSAVYADAGSPLTMGLGKDIGGKPVCADLAKMPHLLVAGTTGSGKS
CCHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCHHHHHHHCCCEEEEECCCCCCC
VGINAMILSLLYKASADQVRMILIDPKMLEMSVYEGIPHLLCPVVTDMRQAGHALNWTVA
CHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHH
EMERRYKLMSKLGVRNLAGFNNKIDEAAKREEKLPNPFSLTPDDPEPLSRLPNIVVVIDE
HHHHHHHHHHHHCHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCCEEEEHHH
LADLMMVVGKKVEELIARIAQKARAAGIHLILATQRPSVDVITGLIKANVPTRMAFQVSS
HHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHH
KIDSRTILDQQGAESLLGMGDMLYLPPGSGLPVRVHGAFVSDDEVHRVVEKLKEQGEPNY
CCCHHHHHHHCCHHHHHCCCCEEEECCCCCCEEEEEEEECCCHHHHHHHHHHHHCCCCHH
IEGLLEGGVSGEGDEGSAEGAGTGAGGTESDPLYDQAVEIVVKNRRASISLVQRHLRIGY
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCH
NRAARLLEQMEQSGLVSAMSSNGNREILVPARETD
HHHHHHHHHHHHCCHHHHHHCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]