| Definition | Burkholderia phymatum STM815 chromosome chromosome 1, complete sequence. |
|---|---|
| Accession | NC_010622 |
| Length | 3,479,187 |
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The map label for this gene is polS [H]
Identifier: 186475257
GI number: 186475257
Start: 557071
End: 557853
Strand: Direct
Name: polS [H]
Synonym: Bphy_0489
Alternate gene names: 186475257
Gene position: 557071-557853 (Clockwise)
Preceding gene: 186475252
Following gene: 186475258
Centisome position: 16.01
GC content: 64.37
Gene sequence:
>783_bases GTGACAGCCCGACTGCAAGGCAAGGTGGCGATTCTCACGGGCGCGGCGAGCGGTATCGGAGAGGCGGTGGCCCGGCGGTA TCTGGAAGAGGGCGCGCACTGCGTACTGGTGGACGTGAAGCCGGCGAGCGATTTCGCGCACGCGCTACGCGAATCGGACG GCGATCGCGTGCTGACCCTGAGCGCAGACGTGACGAAGCGTGACGACATCGGGCGCATCGTTGAGCAAACGGTGCAGCGT TTCGGCCAGATCGATATTCTCTTCAACAACGCGGCGCTGTTCGACATGCGGCCGCTCCTCGACGAATCCTGGGACATCTT CGACAAGCTCTTCGCGGTCAACGTGAAAGGCATGTTCTTTCTGATGCAGGCCGTCGCGCAGCGCATGGTCGAGCAGGGCC ACGGTGGCAAGATCGTCAACATGTCGTCGCAGGCGGGCCGCCGCGGCGAGGCGCTTGTGTCGCATTACTGCGCGACCAAG GCTGCCGTGCTCAGTTATACGCAGTCGGCCGCGCTCGCGCTCGCGCCGCACCAGATCAACGTGAACGGCATCGCACCGGG CGTCGTCGATACGCCAATGTGGGACCAGGTCGATGCGCTCTTCGCGCGTTACGAAAACCGGCCGCTCGGCGAGAAGAAGC GTCTCGTCGGTGAAGCGGTGCCGCTGGGCAGAATGGGACTGCCCGCGGATCTGACGGGGGCGGCGCTGTTCCTCGCATCG TCCGATGCGGATTACATCACCGCGCAAACCCTGAATGTCGACGGCGGCAACTGGATGAGCTGA
Upstream 100 bases:
>100_bases CGATCATTCGATCACAACGAGAGCAATTGCTCGATTACCGGGCGTTAGCTCGTGCTGATCGAAACGTCGATCGAAGAATC AAACGAATCGGAGACAGGTT
Downstream 100 bases:
>100_bases CGGGCATTCATTCGCCGCAACCGCTACCCGGCGCACACGCAACCGCCGGTCACGTACCAAAACGCAAGTACGAATAAAGG AGACAAACGATGAAGCCCAC
Product: sorbitol dehydrogenase
Products: NA
Alternate protein names: L-iditol 2-dehydrogenase; Polyol dehydrogenase [H]
Number of amino acids: Translated: 260; Mature: 259
Protein sequence:
>260_residues MTARLQGKVAILTGAASGIGEAVARRYLEEGAHCVLVDVKPASDFAHALRESDGDRVLTLSADVTKRDDIGRIVEQTVQR FGQIDILFNNAALFDMRPLLDESWDIFDKLFAVNVKGMFFLMQAVAQRMVEQGHGGKIVNMSSQAGRRGEALVSHYCATK AAVLSYTQSAALALAPHQINVNGIAPGVVDTPMWDQVDALFARYENRPLGEKKRLVGEAVPLGRMGLPADLTGAALFLAS SDADYITAQTLNVDGGNWMS
Sequences:
>Translated_260_residues MTARLQGKVAILTGAASGIGEAVARRYLEEGAHCVLVDVKPASDFAHALRESDGDRVLTLSADVTKRDDIGRIVEQTVQR FGQIDILFNNAALFDMRPLLDESWDIFDKLFAVNVKGMFFLMQAVAQRMVEQGHGGKIVNMSSQAGRRGEALVSHYCATK AAVLSYTQSAALALAPHQINVNGIAPGVVDTPMWDQVDALFARYENRPLGEKKRLVGEAVPLGRMGLPADLTGAALFLAS SDADYITAQTLNVDGGNWMS >Mature_259_residues TARLQGKVAILTGAASGIGEAVARRYLEEGAHCVLVDVKPASDFAHALRESDGDRVLTLSADVTKRDDIGRIVEQTVQRF GQIDILFNNAALFDMRPLLDESWDIFDKLFAVNVKGMFFLMQAVAQRMVEQGHGGKIVNMSSQAGRRGEALVSHYCATKA AVLSYTQSAALALAPHQINVNGIAPGVVDTPMWDQVDALFARYENRPLGEKKRLVGEAVPLGRMGLPADLTGAALFLASS DADYITAQTLNVDGGNWMS
Specific function: Catalyzes the oxidation of D-glucitol (sorbitol) to D- fructose, galactitol to D-tagatose and of L-iditol [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI32483357, Length=263, Percent_Identity=35.7414448669202, Blast_Score=127, Evalue=9e-30, Organism=Homo sapiens, GI15277342, Length=265, Percent_Identity=33.5849056603774, Blast_Score=126, Evalue=2e-29, Organism=Homo sapiens, GI10190704, Length=261, Percent_Identity=32.5670498084291, Blast_Score=119, Evalue=2e-27, Organism=Homo sapiens, GI19923817, Length=260, Percent_Identity=31.1538461538462, Blast_Score=118, Evalue=4e-27, Organism=Homo sapiens, GI7705925, Length=256, Percent_Identity=32.03125, Blast_Score=117, Evalue=9e-27, Organism=Homo sapiens, GI59889578, Length=237, Percent_Identity=33.7552742616034, Blast_Score=112, Evalue=2e-25, Organism=Homo sapiens, GI126723750, Length=269, Percent_Identity=31.9702602230483, Blast_Score=102, Evalue=4e-22, Organism=Homo sapiens, GI5031737, Length=259, Percent_Identity=30.5019305019305, Blast_Score=100, Evalue=9e-22, Organism=Homo sapiens, GI33667109, Length=248, Percent_Identity=31.8548387096774, Blast_Score=93, Evalue=3e-19, Organism=Homo sapiens, GI31542939, Length=204, Percent_Identity=32.3529411764706, Blast_Score=91, Evalue=8e-19, Organism=Homo sapiens, GI4758504, Length=267, Percent_Identity=27.3408239700375, Blast_Score=91, Evalue=1e-18, Organism=Homo sapiens, GI66933014, Length=257, Percent_Identity=32.295719844358, Blast_Score=90, Evalue=3e-18, Organism=Homo sapiens, GI40254992, Length=252, Percent_Identity=29.7619047619048, Blast_Score=88, Evalue=7e-18, Organism=Homo sapiens, GI126723191, Length=188, Percent_Identity=35.6382978723404, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI40807363, Length=194, Percent_Identity=26.8041237113402, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI310128830, Length=201, Percent_Identity=28.8557213930348, Blast_Score=82, Evalue=4e-16, Organism=Homo sapiens, GI310115468, Length=201, Percent_Identity=28.8557213930348, Blast_Score=82, Evalue=4e-16, Organism=Homo sapiens, GI4503817, Length=227, Percent_Identity=26.431718061674, Blast_Score=78, Evalue=6e-15, Organism=Homo sapiens, GI224922801, Length=172, Percent_Identity=33.1395348837209, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI83715985, Length=267, Percent_Identity=25.4681647940075, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI7706318, Length=222, Percent_Identity=30.6306306306306, Blast_Score=75, Evalue=7e-14, Organism=Homo sapiens, GI4504505, Length=197, Percent_Identity=28.9340101522843, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI4503301, Length=257, Percent_Identity=25.6809338521401, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI25282469, Length=217, Percent_Identity=26.7281105990783, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI142976729, Length=196, Percent_Identity=27.5510204081633, Blast_Score=72, Evalue=6e-13, Organism=Homo sapiens, GI20149619, Length=198, Percent_Identity=28.2828282828283, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI210032110, Length=189, Percent_Identity=27.5132275132275, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI109715829, Length=196, Percent_Identity=30.6122448979592, Blast_Score=67, Evalue=2e-11, Organism=Escherichia coli, GI1789208, Length=257, Percent_Identity=36.9649805447471, Blast_Score=157, Evalue=5e-40, Organism=Escherichia coli, GI87082100, Length=262, Percent_Identity=33.969465648855, Blast_Score=127, Evalue=7e-31, Organism=Escherichia coli, GI1788459, Length=252, Percent_Identity=34.1269841269841, Blast_Score=126, Evalue=2e-30, Organism=Escherichia coli, GI1787335, Length=259, Percent_Identity=32.046332046332, Blast_Score=123, Evalue=1e-29, Organism=Escherichia coli, GI1790717, Length=255, Percent_Identity=31.7647058823529, Blast_Score=120, Evalue=1e-28, Organism=Escherichia coli, GI87082160, Length=252, Percent_Identity=32.9365079365079, Blast_Score=117, Evalue=8e-28, Organism=Escherichia coli, GI1787905, Length=260, Percent_Identity=34.2307692307692, Blast_Score=110, Evalue=7e-26, Organism=Escherichia coli, GI1789378, Length=266, Percent_Identity=29.3233082706767, Blast_Score=99, Evalue=2e-22, Organism=Escherichia coli, GI1786812, Length=257, Percent_Identity=31.9066147859922, Blast_Score=97, Evalue=1e-21, Organism=Escherichia coli, GI1789057, Length=260, Percent_Identity=27.6923076923077, Blast_Score=90, Evalue=2e-19, Organism=Escherichia coli, GI2367365, Length=259, Percent_Identity=27.027027027027, Blast_Score=81, Evalue=6e-17, Organism=Escherichia coli, GI1787820, Length=182, Percent_Identity=30.2197802197802, Blast_Score=81, Evalue=8e-17, Organism=Escherichia coli, GI2367175, Length=257, Percent_Identity=27.6264591439689, Blast_Score=78, Evalue=7e-16, Organism=Escherichia coli, GI1788891, Length=239, Percent_Identity=27.6150627615063, Blast_Score=65, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17561402, Length=260, Percent_Identity=34.2307692307692, Blast_Score=137, Evalue=4e-33, Organism=Caenorhabditis elegans, GI25147288, Length=260, Percent_Identity=32.3076923076923, Blast_Score=129, Evalue=1e-30, Organism=Caenorhabditis elegans, GI71994600, Length=259, Percent_Identity=33.2046332046332, Blast_Score=123, Evalue=1e-28, Organism=Caenorhabditis elegans, GI17560220, Length=274, Percent_Identity=29.1970802919708, Blast_Score=122, Evalue=2e-28, Organism=Caenorhabditis elegans, GI17562906, Length=267, Percent_Identity=31.4606741573034, Blast_Score=117, Evalue=9e-27, Organism=Caenorhabditis elegans, GI17555706, Length=260, Percent_Identity=31.1538461538462, Blast_Score=116, Evalue=1e-26, Organism=Caenorhabditis elegans, GI71994604, Length=255, Percent_Identity=31.7647058823529, Blast_Score=115, Evalue=3e-26, Organism=Caenorhabditis elegans, GI17538480, Length=270, Percent_Identity=32.962962962963, Blast_Score=114, Evalue=4e-26, Organism=Caenorhabditis elegans, GI17560332, Length=279, Percent_Identity=30.4659498207885, Blast_Score=110, Evalue=5e-25, Organism=Caenorhabditis elegans, GI193204405, Length=273, Percent_Identity=28.9377289377289, Blast_Score=109, Evalue=1e-24, Organism=Caenorhabditis elegans, GI17531453, Length=274, Percent_Identity=29.5620437956204, Blast_Score=109, Evalue=1e-24, Organism=Caenorhabditis elegans, GI17562908, Length=270, Percent_Identity=30.3703703703704, Blast_Score=108, Evalue=3e-24, Organism=Caenorhabditis elegans, GI17560150, Length=274, Percent_Identity=28.4671532846715, Blast_Score=107, Evalue=5e-24, Organism=Caenorhabditis elegans, GI17562990, Length=273, Percent_Identity=28.5714285714286, Blast_Score=107, Evalue=6e-24, Organism=Caenorhabditis elegans, GI17562904, Length=274, Percent_Identity=30.6569343065693, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI17563726, Length=270, Percent_Identity=28.5185185185185, Blast_Score=104, Evalue=4e-23, Organism=Caenorhabditis elegans, GI72000259, Length=271, Percent_Identity=29.520295202952, Blast_Score=101, Evalue=4e-22, Organism=Caenorhabditis elegans, GI17551412, Length=274, Percent_Identity=30.6569343065693, Blast_Score=100, Evalue=7e-22, Organism=Caenorhabditis elegans, GI17560676, Length=261, Percent_Identity=31.4176245210728, Blast_Score=100, Evalue=8e-22, Organism=Caenorhabditis elegans, GI17544670, Length=273, Percent_Identity=28.2051282051282, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17562910, Length=270, Percent_Identity=28.5185185185185, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17559104, Length=269, Percent_Identity=30.4832713754647, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI115534694, Length=255, Percent_Identity=30.1960784313725, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17564282, Length=227, Percent_Identity=29.0748898678414, Blast_Score=91, Evalue=5e-19, Organism=Caenorhabditis elegans, GI17565030, Length=279, Percent_Identity=30.1075268817204, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17538486, Length=267, Percent_Identity=28.8389513108614, Blast_Score=87, Evalue=7e-18, Organism=Caenorhabditis elegans, GI17508895, Length=200, Percent_Identity=27, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI193203117, Length=198, Percent_Identity=27.2727272727273, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17508651, Length=262, Percent_Identity=28.2442748091603, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI193203115, Length=197, Percent_Identity=27.4111675126904, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17568967, Length=197, Percent_Identity=29.9492385786802, Blast_Score=75, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17561272, Length=257, Percent_Identity=25.6809338521401, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17536025, Length=255, Percent_Identity=21.9607843137255, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17538182, Length=267, Percent_Identity=27.7153558052434, Blast_Score=74, Evalue=5e-14, Organism=Caenorhabditis elegans, GI17536651, Length=257, Percent_Identity=22.568093385214, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17567345, Length=193, Percent_Identity=25.9067357512953, Blast_Score=70, Evalue=8e-13, Organism=Caenorhabditis elegans, GI71982365, Length=198, Percent_Identity=25.7575757575758, Blast_Score=67, Evalue=8e-12, Organism=Saccharomyces cerevisiae, GI6323882, Length=196, Percent_Identity=34.6938775510204, Blast_Score=82, Evalue=1e-16, Organism=Saccharomyces cerevisiae, GI6324126, Length=260, Percent_Identity=26.1538461538462, Blast_Score=76, Evalue=4e-15, Organism=Saccharomyces cerevisiae, GI6322227, Length=193, Percent_Identity=29.0155440414508, Blast_Score=69, Evalue=9e-13, Organism=Saccharomyces cerevisiae, GI6322861, Length=194, Percent_Identity=27.319587628866, Blast_Score=65, Evalue=1e-11, Organism=Drosophila melanogaster, GI23397609, Length=252, Percent_Identity=34.9206349206349, Blast_Score=129, Evalue=2e-30, Organism=Drosophila melanogaster, GI21355319, Length=258, Percent_Identity=34.8837209302326, Blast_Score=128, Evalue=4e-30, Organism=Drosophila melanogaster, GI24639444, Length=256, Percent_Identity=34.375, Blast_Score=127, Evalue=8e-30, Organism=Drosophila melanogaster, GI21357041, Length=256, Percent_Identity=31.640625, Blast_Score=111, Evalue=4e-25, Organism=Drosophila melanogaster, GI28571526, Length=259, Percent_Identity=32.4324324324324, Blast_Score=110, Evalue=7e-25, Organism=Drosophila melanogaster, GI24644339, Length=254, Percent_Identity=30.7086614173228, Blast_Score=103, Evalue=1e-22, Organism=Drosophila melanogaster, GI24643142, Length=260, Percent_Identity=30.3846153846154, Blast_Score=94, Evalue=1e-19, Organism=Drosophila melanogaster, GI17737361, Length=268, Percent_Identity=27.9850746268657, Blast_Score=90, Evalue=2e-18, Organism=Drosophila melanogaster, GI24644337, Length=263, Percent_Identity=31.9391634980989, Blast_Score=89, Evalue=4e-18, Organism=Drosophila melanogaster, GI24640492, Length=193, Percent_Identity=27.979274611399, Blast_Score=85, Evalue=6e-17, Organism=Drosophila melanogaster, GI281364892, Length=162, Percent_Identity=33.3333333333333, Blast_Score=84, Evalue=9e-17, Organism=Drosophila melanogaster, GI18859837, Length=194, Percent_Identity=28.8659793814433, Blast_Score=77, Evalue=9e-15, Organism=Drosophila melanogaster, GI21358495, Length=195, Percent_Identity=27.1794871794872, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI24641232, Length=200, Percent_Identity=26, Blast_Score=69, Evalue=4e-12, Organism=Drosophila melanogaster, GI116007236, Length=255, Percent_Identity=25.0980392156863, Blast_Score=67, Evalue=9e-12, Organism=Drosophila melanogaster, GI24665243, Length=170, Percent_Identity=28.2352941176471, Blast_Score=67, Evalue=2e-11, Organism=Drosophila melanogaster, GI221331218, Length=170, Percent_Identity=28.2352941176471, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI24649181, Length=192, Percent_Identity=26.0416666666667, Blast_Score=65, Evalue=6e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.14 [H]
Molecular weight: Translated: 28049; Mature: 27918
Theoretical pI: Translated: 5.66; Mature: 5.66
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 3.5 %Met (Translated Protein) 4.2 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 3.1 %Met (Mature Protein) 3.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTARLQGKVAILTGAASGIGEAVARRYLEEGAHCVLVDVKPASDFAHALRESDGDRVLTL CCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHCCCCCEEEEE SADVTKRDDIGRIVEQTVQRFGQIDILFNNAALFDMRPLLDESWDIFDKLFAVNVKGMFF ECCCCCCHHHHHHHHHHHHHHCCEEEEECCCEEECCHHHHCCHHHHHHHHHHHCHHHHHH LMQAVAQRMVEQGHGGKIVNMSSQAGRRGEALVSHYCATKAAVLSYTQSAALALAPHQIN HHHHHHHHHHHCCCCCEEEEECHHCCCCHHHHHHHHHHHHHHHHHHHHCCEEEECCCEEE VNGIAPGVVDTPMWDQVDALFARYENRPLGEKKRLVGEAVPLGRMGLPADLTGAALFLAS ECCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEEEC SDADYITAQTLNVDGGNWMS CCCCEEEEEEEECCCCCCCC >Mature Secondary Structure TARLQGKVAILTGAASGIGEAVARRYLEEGAHCVLVDVKPASDFAHALRESDGDRVLTL CCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHCCCCCEEEEE SADVTKRDDIGRIVEQTVQRFGQIDILFNNAALFDMRPLLDESWDIFDKLFAVNVKGMFF ECCCCCCHHHHHHHHHHHHHHCCEEEEECCCEEECCHHHHCCHHHHHHHHHHHCHHHHHH LMQAVAQRMVEQGHGGKIVNMSSQAGRRGEALVSHYCATKAAVLSYTQSAALALAPHQIN HHHHHHHHHHHCCCCCEEEEECHHCCCCHHHHHHHHHHHHHHHHHHHHCCEEEECCCEEE VNGIAPGVVDTPMWDQVDALFARYENRPLGEKKRLVGEAVPLGRMGLPADLTGAALFLAS ECCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEEEC SDADYITAQTLNVDGGNWMS CCCCEEEEEEEECCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 7551049 [H]