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The map label for this gene is qseB [H]

Identifier: 186475237

GI number: 186475237

Start: 532855

End: 533517

Strand: Direct

Name: qseB [H]

Synonym: Bphy_0469

Alternate gene names: 186475237

Gene position: 532855-533517 (Clockwise)

Preceding gene: 186475233

Following gene: 186475238

Centisome position: 15.32

GC content: 65.16

Gene sequence:

>663_bases
ATGCGCATACTTCTCGTTGAAGACGACCGGATGATTGCCGAAGGCGTGCGCAAGGCGCTGCGCGGCGAAGGCTTCGCGGT
CGACTGGGTGCAGGACGGCGAGTCCGCGTTGAACGCGGCAGACGGTCAGCCGTACGATCTCGTGCTGCTCGATCTCGGTC
TGCCGAAGCGCGACGGCCTCGACGTGCTGCGCACGCTGCGCACGCGCGGTCATCAGTTGCCCGTGCTGATCGTGACCGCG
CGCGACGCCGTCGCGGATCGTGTAAAAGGACTCGACGCGGGCGCCGACGATTACCTCGTCAAACCGTTCGATCTCGACGA
ACTCGGCGCGCGGATGCGCGCGCTGATCCGCCGTCAGTCGGGGCGCAGCGAATCGACCATTCGCCACGGCAATCTCACGC
TCGATCCCGCTTCGCACCAGGTGACGCTCGACGGCGCGCCCGTCGCACTGTCCGCCCGCGAGTTCGCGCTGCTCGCCGCA
TTGCTCGCGCGGCCGGGCGCTGTGCTGTCGAAGAGTCAGCTCGAAGAAAAGATGTACGGCTGGGGCGAGGAGATCGGCAG
CAATACCGTCGAAGTCTATATTCACGCGCTTCGCAAGAAGCTTGGCGCGGAATTGATCCGCAACGTGCGCGGTCTCGGTT
ACATGATCGCGAAGGAAGCCTGA

Upstream 100 bases:

>100_bases
GCGCGCCTCATATGCAGCGGGCATGTATGAAAGATCGAACGAGGGCTCGGGCGCTAGAATGCTGGCATCTGAAACACACG
GCCGGAACGGCTAGATAGCG

Downstream 100 bases:

>100_bases
CACGATGCGTTCGATTCGCCGTCAACTGCTTTTCTGGCTGCTCGCCATCGTGTTGCTCGGCGTCGGCATCGCGGGCTGGC
TGATCTACCGCCAGGCGCTC

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MRILLVEDDRMIAEGVRKALRGEGFAVDWVQDGESALNAADGQPYDLVLLDLGLPKRDGLDVLRTLRTRGHQLPVLIVTA
RDAVADRVKGLDAGADDYLVKPFDLDELGARMRALIRRQSGRSESTIRHGNLTLDPASHQVTLDGAPVALSAREFALLAA
LLARPGAVLSKSQLEEKMYGWGEEIGSNTVEVYIHALRKKLGAELIRNVRGLGYMIAKEA

Sequences:

>Translated_220_residues
MRILLVEDDRMIAEGVRKALRGEGFAVDWVQDGESALNAADGQPYDLVLLDLGLPKRDGLDVLRTLRTRGHQLPVLIVTA
RDAVADRVKGLDAGADDYLVKPFDLDELGARMRALIRRQSGRSESTIRHGNLTLDPASHQVTLDGAPVALSAREFALLAA
LLARPGAVLSKSQLEEKMYGWGEEIGSNTVEVYIHALRKKLGAELIRNVRGLGYMIAKEA
>Mature_220_residues
MRILLVEDDRMIAEGVRKALRGEGFAVDWVQDGESALNAADGQPYDLVLLDLGLPKRDGLDVLRTLRTRGHQLPVLIVTA
RDAVADRVKGLDAGADDYLVKPFDLDELGARMRALIRRQSGRSESTIRHGNLTLDPASHQVTLDGAPVALSAREFALLAA
LLARPGAVLSKSQLEEKMYGWGEEIGSNTVEVYIHALRKKLGAELIRNVRGLGYMIAKEA

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=219, Percent_Identity=51.1415525114155, Blast_Score=230, Evalue=5e-62,
Organism=Escherichia coli, GI1790552, Length=217, Percent_Identity=46.5437788018433, Blast_Score=198, Evalue=2e-52,
Organism=Escherichia coli, GI87082012, Length=218, Percent_Identity=41.2844036697248, Blast_Score=160, Evalue=5e-41,
Organism=Escherichia coli, GI1786784, Length=221, Percent_Identity=38.0090497737557, Blast_Score=148, Evalue=3e-37,
Organism=Escherichia coli, GI1787375, Length=220, Percent_Identity=35.4545454545455, Blast_Score=141, Evalue=4e-35,
Organism=Escherichia coli, GI1790860, Length=219, Percent_Identity=38.8127853881278, Blast_Score=137, Evalue=6e-34,
Organism=Escherichia coli, GI1786599, Length=223, Percent_Identity=37.6681614349776, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1786911, Length=222, Percent_Identity=37.3873873873874, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1789809, Length=230, Percent_Identity=32.6086956521739, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI2367329, Length=230, Percent_Identity=38.695652173913, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1788394, Length=220, Percent_Identity=34.5454545454545, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1787229, Length=226, Percent_Identity=32.3008849557522, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=29.6943231441048, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI1788550, Length=163, Percent_Identity=34.9693251533742, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI145693140, Length=235, Percent_Identity=28.5106382978723, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1790437, Length=124, Percent_Identity=37.0967741935484, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790299, Length=134, Percent_Identity=32.8358208955224, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788191, Length=121, Percent_Identity=33.8842975206612, Blast_Score=66, Evalue=1e-12,
Organism=Escherichia coli, GI1787487, Length=108, Percent_Identity=35.1851851851852, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1788713, Length=92, Percent_Identity=36.9565217391304, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI48994928, Length=129, Percent_Identity=35.6589147286822, Blast_Score=65, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6322000, Length=176, Percent_Identity=27.8409090909091, Blast_Score=73, Evalue=3e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 24046; Mature: 24046

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILLVEDDRMIAEGVRKALRGEGFAVDWVQDGESALNAADGQPYDLVLLDLGLPKRDGL
CEEEEECCCHHHHHHHHHHHCCCCCEEEEECCCHHHHHCCCCCCEEEEEEECCCCCCCCH
DVLRTLRTRGHQLPVLIVTARDAVADRVKGLDAGADDYLVKPFDLDELGARMRALIRRQS
HHHHHHHHCCCCCCEEEEECCHHHHHHHHCCCCCCCCCEECCCCHHHHHHHHHHHHHHHC
GRSESTIRHGNLTLDPASHQVTLDGAPVALSAREFALLAALLARPGAVLSKSQLEEKMYG
CCCCCEEECCCEEECCCCCEEEECCCCEEECHHHHHHHHHHHHCCCHHHHHHHHHHHHHC
WGEEIGSNTVEVYIHALRKKLGAELIRNVRGLGYMIAKEA
CHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECC
>Mature Secondary Structure
MRILLVEDDRMIAEGVRKALRGEGFAVDWVQDGESALNAADGQPYDLVLLDLGLPKRDGL
CEEEEECCCHHHHHHHHHHHCCCCCEEEEECCCHHHHHCCCCCCEEEEEEECCCCCCCCH
DVLRTLRTRGHQLPVLIVTARDAVADRVKGLDAGADDYLVKPFDLDELGARMRALIRRQS
HHHHHHHHCCCCCCEEEEECCHHHHHHHHCCCCCCCCCEECCCCHHHHHHHHHHHHHHHC
GRSESTIRHGNLTLDPASHQVTLDGAPVALSAREFALLAALLARPGAVLSKSQLEEKMYG
CCCCCEEECCCEEECCCCCEEEECCCCEEECHHHHHHHHHHHHCCCHHHHHHHHHHHHHC
WGEEIGSNTVEVYIHALRKKLGAELIRNVRGLGYMIAKEA
CHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]