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The map label for this gene is ywlC [H]

Identifier: 186475233

GI number: 186475233

Start: 527737

End: 528780

Strand: Direct

Name: ywlC [H]

Synonym: Bphy_0465

Alternate gene names: 186475233

Gene position: 527737-528780 (Clockwise)

Preceding gene: 186475232

Following gene: 186475237

Centisome position: 15.17

GC content: 66.28

Gene sequence:

>1044_bases
ATGCCGGATCAAACGAAACCTGGCGACGTGGCGTCGAGCGTCGGCGCCGACGAGATCGCGCATGCAGCGGCGATGCTCGA
TGCGGGCCAACTCGTCGCGTTTCCTACAGAGACCGTGTACGGACTCGGCGGCGATGCCGAAAGTCCCGATGCCATCGCGC
GTATATATGCCGCTAAGGGAAGGCCGTCGAATCACCCTGTGATCGTCCATCTGGCGCCGAACGGTGATCCGAACTATTGG
GTCGCGCAGTTGCCCTCCGATGCACAGCGCCTGATCGACGCGTTCTGGCCGGGTCCGCTTACGCTCATTCTCAAACGTGC
CGCGCATATTCCGGCAGCAGTGAGCGGTGGCCAGGATTCCGTTGGATTGCGTTGTCCGTCGCATCCTGTTGCGCAGTCGC
TGCTGACGGCGTTCAGCGCGTTGCGCAACGGACATGGCGGCGTGGCGGCACCGTCGGCGAACCGCTTCGGCCACGTCAGC
CCGACCACGGCGCAACACGTGCGCGAGGAGTTCGGCGATGCAATCCACGTGCTCGACGGCGGGCCGTCGGACGTGGGGAT
CGAGTCGACTATCGTCGATCTGTCGCGTGGGTTCCCGGCGCTGTTGCGGCCGGGGCATGTCACGCCGCAAGACATCGCCG
ACGTGCTCGGCGAAATGCCGCGTTTGCCCGATGGTTCGGATGCGAGCGCACCGCGCGCATCCGGCACGCTGAAGGCGCAC
TATGCGCCGCGCACACCGCTCGCGTTGCTGCCTTTCGACGTGCTCGAGCCGCTGCTGGCCGCGCGCGCTCCCGGCGAGCG
CGTGGCGCTGGTCGCGCGTGCGTCGCGCGCCGGGCGGTGGGCGGAAGCGCAGGGCGTGCATTTCGTCGCCGCGCCGGAAG
ATCCGCATCTGTATGCGCGCGATCTCTATGGTTTGCTGCGCGCGCTGGATAGAGCGAATGTGTCGCGCATCCTGATCGAG
AAGCTGCCCGACACCATCGAATGGATTGCCGTCAACGACAGACTGGGACGTGCAGCGGCGGCGTTCGAGGCGAATGAAGC
GTGA

Upstream 100 bases:

>100_bases
GCACGTGAACTTCACGGCCGCGACGCTCGAGCATGCGCGTTCCGCGGCGCGCGATTGCGCGCGACTGCTGCATATTCCGA
CGAACTGAGCACGAGCCCCG

Downstream 100 bases:

>100_bases
CGCGGTCGTAGTGGAACGAACCTTCCAAAAACAAAGAGCCCGGCTCGCGAGAGCCGGGCTCTTTTGCATCGCAGGAAGCA
GGTAATTCGCTTACTTGCCG

Product: Sua5/YciO/YrdC/YwlC family protein

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 347; Mature: 346

Protein sequence:

>347_residues
MPDQTKPGDVASSVGADEIAHAAAMLDAGQLVAFPTETVYGLGGDAESPDAIARIYAAKGRPSNHPVIVHLAPNGDPNYW
VAQLPSDAQRLIDAFWPGPLTLILKRAAHIPAAVSGGQDSVGLRCPSHPVAQSLLTAFSALRNGHGGVAAPSANRFGHVS
PTTAQHVREEFGDAIHVLDGGPSDVGIESTIVDLSRGFPALLRPGHVTPQDIADVLGEMPRLPDGSDASAPRASGTLKAH
YAPRTPLALLPFDVLEPLLAARAPGERVALVARASRAGRWAEAQGVHFVAAPEDPHLYARDLYGLLRALDRANVSRILIE
KLPDTIEWIAVNDRLGRAAAAFEANEA

Sequences:

>Translated_347_residues
MPDQTKPGDVASSVGADEIAHAAAMLDAGQLVAFPTETVYGLGGDAESPDAIARIYAAKGRPSNHPVIVHLAPNGDPNYW
VAQLPSDAQRLIDAFWPGPLTLILKRAAHIPAAVSGGQDSVGLRCPSHPVAQSLLTAFSALRNGHGGVAAPSANRFGHVS
PTTAQHVREEFGDAIHVLDGGPSDVGIESTIVDLSRGFPALLRPGHVTPQDIADVLGEMPRLPDGSDASAPRASGTLKAH
YAPRTPLALLPFDVLEPLLAARAPGERVALVARASRAGRWAEAQGVHFVAAPEDPHLYARDLYGLLRALDRANVSRILIE
KLPDTIEWIAVNDRLGRAAAAFEANEA
>Mature_346_residues
PDQTKPGDVASSVGADEIAHAAAMLDAGQLVAFPTETVYGLGGDAESPDAIARIYAAKGRPSNHPVIVHLAPNGDPNYWV
AQLPSDAQRLIDAFWPGPLTLILKRAAHIPAAVSGGQDSVGLRCPSHPVAQSLLTAFSALRNGHGGVAAPSANRFGHVSP
TTAQHVREEFGDAIHVLDGGPSDVGIESTIVDLSRGFPALLRPGHVTPQDIADVLGEMPRLPDGSDASAPRASGTLKAHY
APRTPLALLPFDVLEPLLAARAPGERVALVARASRAGRWAEAQGVHFVAAPEDPHLYARDLYGLLRALDRANVSRILIEK
LPDTIEWIAVNDRLGRAAAAFEANEA

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Homo sapiens, GI58761510, Length=192, Percent_Identity=31.7708333333333, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI2367210, Length=172, Percent_Identity=31.3953488372093, Blast_Score=76, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6321269, Length=398, Percent_Identity=30.9045226130653, Blast_Score=132, Evalue=6e-32,
Organism=Drosophila melanogaster, GI78707274, Length=190, Percent_Identity=27.8947368421053, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 36436; Mature: 36305

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDQTKPGDVASSVGADEIAHAAAMLDAGQLVAFPTETVYGLGGDAESPDAIARIYAAKG
CCCCCCCCHHHHHCCHHHHHHHHHHHCCCCEEEECCHHEEECCCCCCCHHHHHHHHHHCC
RPSNHPVIVHLAPNGDPNYWVAQLPSDAQRLIDAFWPGPLTLILKRAAHIPAAVSGGQDS
CCCCCCEEEEECCCCCCCEEEEECCHHHHHHHHHHCCCHHHHHHHHHHCCCCEECCCCCC
VGLRCPSHPVAQSLLTAFSALRNGHGGVAAPSANRFGHVSPTTAQHVREEFGDAIHVLDG
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEECC
GPSDVGIESTIVDLSRGFPALLRPGHVTPQDIADVLGEMPRLPDGSDASAPRASGTLKAH
CCCCCCHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEE
YAPRTPLALLPFDVLEPLLAARAPGERVALVARASRAGRWAEAQGVHFVAAPEDPHLYAR
CCCCCCCEECCHHHHHHHHHHCCCCCEEEEEEEHHHCCCCHHHCCEEEEECCCCCCHHHH
DLYGLLRALDRANVSRILIEKLPDTIEWIAVNDRLGRAAAAFEANEA
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHCCCCCCC
>Mature Secondary Structure 
PDQTKPGDVASSVGADEIAHAAAMLDAGQLVAFPTETVYGLGGDAESPDAIARIYAAKG
CCCCCCCHHHHHCCHHHHHHHHHHHCCCCEEEECCHHEEECCCCCCCHHHHHHHHHHCC
RPSNHPVIVHLAPNGDPNYWVAQLPSDAQRLIDAFWPGPLTLILKRAAHIPAAVSGGQDS
CCCCCCEEEEECCCCCCCEEEEECCHHHHHHHHHHCCCHHHHHHHHHHCCCCEECCCCCC
VGLRCPSHPVAQSLLTAFSALRNGHGGVAAPSANRFGHVSPTTAQHVREEFGDAIHVLDG
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEECC
GPSDVGIESTIVDLSRGFPALLRPGHVTPQDIADVLGEMPRLPDGSDASAPRASGTLKAH
CCCCCCHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEE
YAPRTPLALLPFDVLEPLLAARAPGERVALVARASRAGRWAEAQGVHFVAAPEDPHLYAR
CCCCCCCEECCHHHHHHHHHHCCCCCEEEEEEEHHHCCCCHHHCCEEEEECCCCCCHHHH
DLYGLLRALDRANVSRILIEKLPDTIEWIAVNDRLGRAAAAFEANEA
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]