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The map label for this gene is pdxA [H]

Identifier: 186475167

GI number: 186475167

Start: 456029

End: 457030

Strand: Direct

Name: pdxA [H]

Synonym: Bphy_0398

Alternate gene names: 186475167

Gene position: 456029-457030 (Clockwise)

Preceding gene: 186475166

Following gene: 186475168

Centisome position: 13.11

GC content: 67.56

Gene sequence:

>1002_bases
ATGATCGCTGCCCAGCCCTCGAACGACCCGCTTCACATCGCGATCACCACGGGCGAGCCGGCTGGCGTCGGTCCTGAACT
GACGGCACAGGCGCTCGCAGCGGCGGGCGCACATTGGCCGGACGCGCGCTTCTCGGTGCTCGGCGACAGCGCTCTGATGG
ACGAGCGTGCGAAGGCCGTCGGCGTCGACTGGGCCGCGCAGCAGGGCCGTCGCATTGCCATGCAGCATCATGCGCTTGCC
GTGCCGGCGCTGGCCGGGAAGCTGGATGCACAGAACGGCCCGTATGTGCTCGGGCTGCTCGATGCGGCTATCGATGGCGC
GCTGGCGGGTACGTTCGACGCTATCGTCACCGCGCCGCTGCAGAAGAGCACGATCAACGATGCCGGCGTGCCGTTCACCG
GCCACACCGAATATCTGGCGGAGCGCACGGGGACGCCGCATGTCGTGATGATGCTGGCGGGCACAGGCGCAAGGCCGCTG
CGCGTCGCGCTGGCGACTACGCATCTGCCGCTGAAGGACGTGTCGGCGGCGTTGACGGTCGACGGCATCGCCGACACGCT
GCGCATCATCGATCACGACTTGCGTCGCCATTTTGGCCTGCCCGCGCCGCGCATTCTCGTCACGGGTCTGAATCCTCACG
CGGGCGAGAACGGCTATCTCGGGCGCGAGGAAATCGATGTGATCTCGCCCGCGCTGCGACTGGCGAACGGGCAGGGCATC
GACGCGCGCGGTCCGTATCCGGCGGATACTCTGTTCCAGCCGCGTTATCTGAACGAAGCCGATTGCGTGCTCGCGATGTT
CCACGATCAGGGCCTGCCCGTGCTCAAATATGCGACGTTCGGCGAAGGCATCAACGTGACCTTGGGCCTGCCGATCATCC
GCACGTCCGTCGACCACGGCACGGCGCTCGATCTTGCCGGTACGGGCCGCGCGGATGCGGGCAGCCTGATCGCCGCGATC
GACACCGCTGTTTTCATGGCGCGCAACCGGCGCGCCGCGTGA

Upstream 100 bases:

>100_bases
GGCTGCGTGAACTGCGTGACACCGCATATGTCGATTACAAGGTAGGCCCGGTCACGGGCACATCCGCGGACAACACCGCG
CAATAACCTCTGGAATCGTC

Downstream 100 bases:

>100_bases
TTTTTTCGTAGCTTCTTTCGATGTCCAACAGTTCAAGCAGACAGCACCAGGGCCACTTCGCGCGCAAGCGCTTCGGACAG
AATTTTCTGGTCGACCTGGG

Product: 4-hydroxythreonine-4-phosphate dehydrogenase

Products: NA

Alternate protein names: 4-(phosphohydroxy)-L-threonine dehydrogenase [H]

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MIAAQPSNDPLHIAITTGEPAGVGPELTAQALAAAGAHWPDARFSVLGDSALMDERAKAVGVDWAAQQGRRIAMQHHALA
VPALAGKLDAQNGPYVLGLLDAAIDGALAGTFDAIVTAPLQKSTINDAGVPFTGHTEYLAERTGTPHVVMMLAGTGARPL
RVALATTHLPLKDVSAALTVDGIADTLRIIDHDLRRHFGLPAPRILVTGLNPHAGENGYLGREEIDVISPALRLANGQGI
DARGPYPADTLFQPRYLNEADCVLAMFHDQGLPVLKYATFGEGINVTLGLPIIRTSVDHGTALDLAGTGRADAGSLIAAI
DTAVFMARNRRAA

Sequences:

>Translated_333_residues
MIAAQPSNDPLHIAITTGEPAGVGPELTAQALAAAGAHWPDARFSVLGDSALMDERAKAVGVDWAAQQGRRIAMQHHALA
VPALAGKLDAQNGPYVLGLLDAAIDGALAGTFDAIVTAPLQKSTINDAGVPFTGHTEYLAERTGTPHVVMMLAGTGARPL
RVALATTHLPLKDVSAALTVDGIADTLRIIDHDLRRHFGLPAPRILVTGLNPHAGENGYLGREEIDVISPALRLANGQGI
DARGPYPADTLFQPRYLNEADCVLAMFHDQGLPVLKYATFGEGINVTLGLPIIRTSVDHGTALDLAGTGRADAGSLIAAI
DTAVFMARNRRAA
>Mature_333_residues
MIAAQPSNDPLHIAITTGEPAGVGPELTAQALAAAGAHWPDARFSVLGDSALMDERAKAVGVDWAAQQGRRIAMQHHALA
VPALAGKLDAQNGPYVLGLLDAAIDGALAGTFDAIVTAPLQKSTINDAGVPFTGHTEYLAERTGTPHVVMMLAGTGARPL
RVALATTHLPLKDVSAALTVDGIADTLRIIDHDLRRHFGLPAPRILVTGLNPHAGENGYLGREEIDVISPALRLANGQGI
DARGPYPADTLFQPRYLNEADCVLAMFHDQGLPVLKYATFGEGINVTLGLPIIRTSVDHGTALDLAGTGRADAGSLIAAI
DTAVFMARNRRAA

Specific function: Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) [H]

COG id: COG1995

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxA family [H]

Homologues:

Organism=Escherichia coli, GI1786237, Length=330, Percent_Identity=51.2121212121212, Blast_Score=317, Evalue=5e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005255 [H]

Pfam domain/function: PF04166 PdxA [H]

EC number: =1.1.1.262 [H]

Molecular weight: Translated: 34755; Mature: 34755

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAAQPSNDPLHIAITTGEPAGVGPELTAQALAAAGAHWPDARFSVLGDSALMDERAKAV
CCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCEEEECCHHHHHHHHHHC
GVDWAAQQGRRIAMQHHALAVPALAGKLDAQNGPYVLGLLDAAIDGALAGTFDAIVTAPL
CCCHHHHCCCEEEHHHHHEEHHHHHCCCCCCCCCEEEEEEHHHHCCHHHHHHHHHHCCCC
QKSTINDAGVPFTGHTEYLAERTGTPHVVMMLAGTGARPLRVALATTHLPLKDVSAALTV
CCCCCCCCCCCCCCCHHHHHHCCCCCEEEEEEECCCCCCEEEEEEECCCCHHHHHHEEEE
DGIADTLRIIDHDLRRHFGLPAPRILVTGLNPHAGENGYLGREEIDVISPALRLANGQGI
HHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCC
DARGPYPADTLFQPRYLNEADCVLAMFHDQGLPVLKYATFGEGINVTLGLPIIRTSVDHG
CCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEEECCCCEEEEECCEEEEECCCCC
TALDLAGTGRADAGSLIAAIDTAVFMARNRRAA
CEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MIAAQPSNDPLHIAITTGEPAGVGPELTAQALAAAGAHWPDARFSVLGDSALMDERAKAV
CCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCEEEECCHHHHHHHHHHC
GVDWAAQQGRRIAMQHHALAVPALAGKLDAQNGPYVLGLLDAAIDGALAGTFDAIVTAPL
CCCHHHHCCCEEEHHHHHEEHHHHHCCCCCCCCCEEEEEEHHHHCCHHHHHHHHHHCCCC
QKSTINDAGVPFTGHTEYLAERTGTPHVVMMLAGTGARPLRVALATTHLPLKDVSAALTV
CCCCCCCCCCCCCCCHHHHHHCCCCCEEEEEEECCCCCCEEEEEEECCCCHHHHHHEEEE
DGIADTLRIIDHDLRRHFGLPAPRILVTGLNPHAGENGYLGREEIDVISPALRLANGQGI
HHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCC
DARGPYPADTLFQPRYLNEADCVLAMFHDQGLPVLKYATFGEGINVTLGLPIIRTSVDHG
CCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEEECCCCEEEEECCEEEEECCCCC
TALDLAGTGRADAGSLIAAIDTAVFMARNRRAA
CEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA