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The map label for this gene is surA [H]

Identifier: 186475166

GI number: 186475166

Start: 454623

End: 456014

Strand: Direct

Name: surA [H]

Synonym: Bphy_0397

Alternate gene names: 186475166

Gene position: 454623-456014 (Clockwise)

Preceding gene: 186475165

Following gene: 186475167

Centisome position: 13.07

GC content: 63.94

Gene sequence:

>1392_bases
GTGGCAATCATGAAAAAGCTTCGCCTGGCAACGTTCGCGACCGGCTTCGCTGCGGCCGCTTCCATTCTGCTGGCCGGACC
CGCGCACGCGCAGGCACTGAACGGCAGCGGCAGTGCCCAAACAGTCGATACGATCGCGGCTGTCGTCAATAACGGCGTGA
TTACGCAGCGCGAGCTGGACATGCGCGTTGGCCTGATCACGAAGCGGTTGAATCAGCAGCACGCGCCGATTCCGCCCGCC
GACCAGTTGCGCCAGCAGGTGCTCAACCAGATGGTGCTTGAGCGCATCCAGTTGCAAAAGGCGCGCGAAGACGGCATCAC
CGTCGACGACGCGACGGTGCAGCGCACACTCGAACGTCTCGCCCAGGCGAACAACTTGCAGCTCGACATGTACCGCGCAC
GTATCGAGGCGCAAGGCGTGCCCTGGACGACCTTCATGGGCGACGCGAAGACGGAGCTGATCCTGTCGCGTCTGCGCGAA
AAGGAAGTGGACAGCAAGGTCACGGTTTCGGACGCGGAAGTGGCGAACTACATCGCCAGCCAGCGCGGCCCGACGGCAGG
CCTCGCGAGCGATCTGCACCTCGAGCACATTTTCCTGAAAGCGCCGCTCAATGCGTCCCAGACGGATATCGAAGCAGCCC
AGGCCAAGGCGAACGCGCTGCTTCAGGAAGCCTTGAAGGGCGATAACTTCGGCAAGCTCGCGAAGTCGAATTCGCAGGCT
CCCGATGCGTCGAAGGGCGGCGATCTGGGCTTTCAGGCACCGTCCAGGCTACCGGCTGAATTCGTGACGGCGGCTGCGAC
GCTGCGTCCGGGCCAGGTCAACCCGTCCGTGATCCGCACCAACGACGGCTTCGAGATTGTGCGTCTCGTCGAGCGCCGCT
CGGGTCAGGGCTCGGCTTCCGCCGACTCGACGAAGCTCGTGCAGACGCACGTGCGCCACATCTTGCTGCGTGTCGGTGAC
GGCATGTCGGAGCCGCAAGCACGCCAGAAGCTGTTGGAAATCCGCCAGGAAATCGAAGCGGGCCAAGGCGACTTCGACAA
GTTCGCGCGCACGTATTCGCAGGACGGCTCGGCGTCGCAGGGTGGCGATCTGGGCTGGATCAGCCCGGGCGAAACGGTCC
CGGAGTTCGAGCGGGCGATGAATTCGCTGCAGGACAACCAGATCAGCCAGCCTGTGCGAAGCGAGTACGGCTACCACCTG
ATCCAGGTGCTCGGCCGCCGGGAAGCGGAGGGCTCGGTCTCTCAGCAGATGGATCTGGCGCGTCAGGCGATCGGCCAGCG
CAAGGCGGAACAGGCCTATGCCGACTGGCTGCGTGAACTGCGTGACACCGCATATGTCGATTACAAGGTAGGCCCGGTCA
CGGGCACATCCGCGGACAACACCGCGCAATAA

Upstream 100 bases:

>100_bases
AGAACGGAAACGCAACTTGTTGCATGGGATCCGGGGGCGCGCCAAAACGCATCCGGATCGAAAAGACGGGCCGAGCGTGC
CCGACATCTTTGGAGTATCT

Downstream 100 bases:

>100_bases
CCTCTGGAATCGTCATGATCGCTGCCCAGCCCTCGAACGACCCGCTTCACATCGCGATCACCACGGGCGAGCCGGCTGGC
GTCGGTCCTGAACTGACGGC

Product: SurA domain-containing protein

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase surA; PPIase surA; Rotamase surA [H]

Number of amino acids: Translated: 463; Mature: 462

Protein sequence:

>463_residues
MAIMKKLRLATFATGFAAAASILLAGPAHAQALNGSGSAQTVDTIAAVVNNGVITQRELDMRVGLITKRLNQQHAPIPPA
DQLRQQVLNQMVLERIQLQKAREDGITVDDATVQRTLERLAQANNLQLDMYRARIEAQGVPWTTFMGDAKTELILSRLRE
KEVDSKVTVSDAEVANYIASQRGPTAGLASDLHLEHIFLKAPLNASQTDIEAAQAKANALLQEALKGDNFGKLAKSNSQA
PDASKGGDLGFQAPSRLPAEFVTAAATLRPGQVNPSVIRTNDGFEIVRLVERRSGQGSASADSTKLVQTHVRHILLRVGD
GMSEPQARQKLLEIRQEIEAGQGDFDKFARTYSQDGSASQGGDLGWISPGETVPEFERAMNSLQDNQISQPVRSEYGYHL
IQVLGRREAEGSVSQQMDLARQAIGQRKAEQAYADWLRELRDTAYVDYKVGPVTGTSADNTAQ

Sequences:

>Translated_463_residues
MAIMKKLRLATFATGFAAAASILLAGPAHAQALNGSGSAQTVDTIAAVVNNGVITQRELDMRVGLITKRLNQQHAPIPPA
DQLRQQVLNQMVLERIQLQKAREDGITVDDATVQRTLERLAQANNLQLDMYRARIEAQGVPWTTFMGDAKTELILSRLRE
KEVDSKVTVSDAEVANYIASQRGPTAGLASDLHLEHIFLKAPLNASQTDIEAAQAKANALLQEALKGDNFGKLAKSNSQA
PDASKGGDLGFQAPSRLPAEFVTAAATLRPGQVNPSVIRTNDGFEIVRLVERRSGQGSASADSTKLVQTHVRHILLRVGD
GMSEPQARQKLLEIRQEIEAGQGDFDKFARTYSQDGSASQGGDLGWISPGETVPEFERAMNSLQDNQISQPVRSEYGYHL
IQVLGRREAEGSVSQQMDLARQAIGQRKAEQAYADWLRELRDTAYVDYKVGPVTGTSADNTAQ
>Mature_462_residues
AIMKKLRLATFATGFAAAASILLAGPAHAQALNGSGSAQTVDTIAAVVNNGVITQRELDMRVGLITKRLNQQHAPIPPAD
QLRQQVLNQMVLERIQLQKAREDGITVDDATVQRTLERLAQANNLQLDMYRARIEAQGVPWTTFMGDAKTELILSRLREK
EVDSKVTVSDAEVANYIASQRGPTAGLASDLHLEHIFLKAPLNASQTDIEAAQAKANALLQEALKGDNFGKLAKSNSQAP
DASKGGDLGFQAPSRLPAEFVTAAATLRPGQVNPSVIRTNDGFEIVRLVERRSGQGSASADSTKLVQTHVRHILLRVGDG
MSEPQARQKLLEIRQEIEAGQGDFDKFARTYSQDGSASQGGDLGWISPGETVPEFERAMNSLQDNQISQPVRSEYGYHLI
QVLGRREAEGSVSQQMDLARQAIGQRKAEQAYADWLRELRDTAYVDYKVGPVTGTSADNTAQ

Specific function: Chaperone involved in the correct folding and assembly of outer membrane proteins. It recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasm. Note=Is capable of associating with the outer membrane (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PpiC domains [H]

Homologues:

Organism=Escherichia coli, GI1786238, Length=441, Percent_Identity=33.1065759637188, Blast_Score=214, Evalue=1e-56,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023034
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 50287; Mature: 50156

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIMKKLRLATFATGFAAAASILLAGPAHAQALNGSGSAQTVDTIAAVVNNGVITQRELD
CHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHH
MRVGLITKRLNQQHAPIPPADQLRQQVLNQMVLERIQLQKAREDGITVDDATVQRTLERL
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
AQANNLQLDMYRARIEAQGVPWTTFMGDAKTELILSRLREKEVDSKVTVSDAEVANYIAS
HHCCCCCHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHH
QRGPTAGLASDLHLEHIFLKAPLNASQTDIEAAQAKANALLQEALKGDNFGKLAKSNSQA
CCCCCCCCHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCC
PDASKGGDLGFQAPSRLPAEFVTAAATLRPGQVNPSVIRTNDGFEIVRLVERRSGQGSAS
CCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHHCCCCCCCC
ADSTKLVQTHVRHILLRVGDGMSEPQARQKLLEIRQEIEAGQGDFDKFARTYSQDGSASQ
CCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCC
GGDLGWISPGETVPEFERAMNSLQDNQISQPVRSEYGYHLIQVLGRREAEGSVSQQMDLA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
RQAIGQRKAEQAYADWLRELRDTAYVDYKVGPVTGTSADNTAQ
HHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCC
>Mature Secondary Structure 
AIMKKLRLATFATGFAAAASILLAGPAHAQALNGSGSAQTVDTIAAVVNNGVITQRELD
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHH
MRVGLITKRLNQQHAPIPPADQLRQQVLNQMVLERIQLQKAREDGITVDDATVQRTLERL
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
AQANNLQLDMYRARIEAQGVPWTTFMGDAKTELILSRLREKEVDSKVTVSDAEVANYIAS
HHCCCCCHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHH
QRGPTAGLASDLHLEHIFLKAPLNASQTDIEAAQAKANALLQEALKGDNFGKLAKSNSQA
CCCCCCCCHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCC
PDASKGGDLGFQAPSRLPAEFVTAAATLRPGQVNPSVIRTNDGFEIVRLVERRSGQGSAS
CCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHHCCCCCCCC
ADSTKLVQTHVRHILLRVGDGMSEPQARQKLLEIRQEIEAGQGDFDKFARTYSQDGSASQ
CCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCC
GGDLGWISPGETVPEFERAMNSLQDNQISQPVRSEYGYHLIQVLGRREAEGSVSQQMDLA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
RQAIGQRKAEQAYADWLRELRDTAYVDYKVGPVTGTSADNTAQ
HHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA