Click here to switch to the map view.

The map label for this gene is nagA [H]

Identifier: 186475062

GI number: 186475062

Start: 333493

End: 334596

Strand: Direct

Name: nagA [H]

Synonym: Bphy_0293

Alternate gene names: 186475062

Gene position: 333493-334596 (Clockwise)

Preceding gene: 186475061

Following gene: 186475063

Centisome position: 9.59

GC content: 65.13

Gene sequence:

>1104_bases
ATGCTGACCGGAAACATACTCACCCCAGAAGGCTGGATCCACGGCACGATCGAATTCGAAAGCGGCCGCATATCGGCTAT
CAAGGGCGACGCCGTCGATCCGTCGAAGAACGATGCTCCATACATCCTGCCTGGCTTCATCGATCTGCACGTGCACGGTG
GCGGCGGCGCCGACGTGATGGAGGCGGGCAACGCGATCGAAGCGATCACGCGCACGCATGCACGCTTCGGCACGACTAGT
CTGCTGGCCACCACGATGACGGCGCCGCGCGACGAGCTGATGAGCGTCGTCGCGGGCCTCGGCGACGTAGCGAAGAACCG
CGTGCCTGGCGGCGCGCGCGTGCTCGGTGTGCACCTCGAGGGTCCCTACATCAATCCCGGCAAGCTCGGCGCGCAGCCTG
ACGCAGCCGTGTCGGCCGTGCTCGACGAAGTGCTGAAGTATCTGTCAATCGCGCCGATCCGCGTTGTCACGATCGCGCCG
GAAATTTCCGGCCACATGGACATCATTTCGGAGATCAACGCGCGCGGCGTGCGCGTGCAACTCGGCCACTCGCTCGGCAC
GTACGACGACGCCGTAGCCGCGATGAAGCACGGCGCGCGCAGCTTCACGCACCTGTTCAACGCGATGTCGGCGCTGCATC
ACCGTAATCCAGGGATGGTGGGCGCGGCGCTCGCGCACGCTGAATACGCGGAAATCATTCCCGACCTGCTGCACGTGCAT
CCGGGCGCGATCCGCGCCGCGATGCGCGCGATCCCACGTCTCTACGTGGTGACGGACAGCACGTCGGCGACGGGCATGCC
CGATGGCGAATACCGCCTCGGCAGCCAGCACGTGACGAAGTGCCTCGGCGGCGTACGACTCGCCGATGGCACGCTTGCGG
GCAGCACGCTGACGATGGATCAGGCGCTGCGCAATCTGGTATCGCTCGGCCTGCCGGTGGCCGATGTTTCAAACCGTATG
TCCCGTTATGCCGCCGACTACCTCGGCATCGAAGACCGTGGCCGCCTCGCGCGCGGCGCGTGGGCCGATGTCGTGGTGTT
CGACCGCGAACTGGCGCTGACGGCGACTTACGTCGAAGGAGAATCGATTGTCGAATATGCTTAA

Upstream 100 bases:

>100_bases
GTCGCTGAATTGCGGCTTTGATCCTGCGTGCAACGAATACATTGAACGCAGACGGCAAAGAATCAGTAACGCACTGCATA
ACGCAACATCAGAGAGACTC

Downstream 100 bases:

>100_bases
AGAGGCGCTAGCGTCCGCTGACGTGGTCGCCGCGCAACTCAACGATACGTCGCGTGTGGAAGCGCTCGCGGCCCGCCTTG
CGCTGGAGCCGCGGCATGTC

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MLTGNILTPEGWIHGTIEFESGRISAIKGDAVDPSKNDAPYILPGFIDLHVHGGGGADVMEAGNAIEAITRTHARFGTTS
LLATTMTAPRDELMSVVAGLGDVAKNRVPGGARVLGVHLEGPYINPGKLGAQPDAAVSAVLDEVLKYLSIAPIRVVTIAP
EISGHMDIISEINARGVRVQLGHSLGTYDDAVAAMKHGARSFTHLFNAMSALHHRNPGMVGAALAHAEYAEIIPDLLHVH
PGAIRAAMRAIPRLYVVTDSTSATGMPDGEYRLGSQHVTKCLGGVRLADGTLAGSTLTMDQALRNLVSLGLPVADVSNRM
SRYAADYLGIEDRGRLARGAWADVVVFDRELALTATYVEGESIVEYA

Sequences:

>Translated_367_residues
MLTGNILTPEGWIHGTIEFESGRISAIKGDAVDPSKNDAPYILPGFIDLHVHGGGGADVMEAGNAIEAITRTHARFGTTS
LLATTMTAPRDELMSVVAGLGDVAKNRVPGGARVLGVHLEGPYINPGKLGAQPDAAVSAVLDEVLKYLSIAPIRVVTIAP
EISGHMDIISEINARGVRVQLGHSLGTYDDAVAAMKHGARSFTHLFNAMSALHHRNPGMVGAALAHAEYAEIIPDLLHVH
PGAIRAAMRAIPRLYVVTDSTSATGMPDGEYRLGSQHVTKCLGGVRLADGTLAGSTLTMDQALRNLVSLGLPVADVSNRM
SRYAADYLGIEDRGRLARGAWADVVVFDRELALTATYVEGESIVEYA
>Mature_367_residues
MLTGNILTPEGWIHGTIEFESGRISAIKGDAVDPSKNDAPYILPGFIDLHVHGGGGADVMEAGNAIEAITRTHARFGTTS
LLATTMTAPRDELMSVVAGLGDVAKNRVPGGARVLGVHLEGPYINPGKLGAQPDAAVSAVLDEVLKYLSIAPIRVVTIAP
EISGHMDIISEINARGVRVQLGHSLGTYDDAVAAMKHGARSFTHLFNAMSALHHRNPGMVGAALAHAEYAEIIPDLLHVH
PGAIRAAMRAIPRLYVVTDSTSATGMPDGEYRLGSQHVTKCLGGVRLADGTLAGSTLTMDQALRNLVSLGLPVADVSNRM
SRYAADYLGIEDRGRLARGAWADVVVFDRELALTATYVEGESIVEYA

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=412, Percent_Identity=32.7669902912621, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI224922791, Length=407, Percent_Identity=32.9238329238329, Blast_Score=162, Evalue=3e-40,
Organism=Escherichia coli, GI1786892, Length=337, Percent_Identity=33.8278931750742, Blast_Score=142, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI17553768, Length=371, Percent_Identity=31.266846361186, Blast_Score=150, Evalue=8e-37,
Organism=Drosophila melanogaster, GI19920392, Length=341, Percent_Identity=34.8973607038123, Blast_Score=174, Evalue=7e-44,
Organism=Drosophila melanogaster, GI281361140, Length=354, Percent_Identity=33.6158192090396, Blast_Score=169, Evalue=4e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 38750; Mature: 38750

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTGNILTPEGWIHGTIEFESGRISAIKGDAVDPSKNDAPYILPGFIDLHVHGGGGADVM
CCCCCEECCCCCEEEEEEECCCEEEEEECCCCCCCCCCCCEEECCEEEEEEECCCCCHHH
EAGNAIEAITRTHARFGTTSLLATTMTAPRDELMSVVAGLGDVAKNRVPGGARVLGVHLE
HCCCHHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEC
GPYINPGKLGAQPDAAVSAVLDEVLKYLSIAPIRVVTIAPEISGHMDIISEINARGVRVQ
CCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHCCCCCEEEE
LGHSLGTYDDAVAAMKHGARSFTHLFNAMSALHHRNPGMVGAALAHAEYAEIIPDLLHVH
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCC
PGAIRAAMRAIPRLYVVTDSTSATGMPDGEYRLGSQHVTKCLGGVRLADGTLAGSTLTMD
CHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCEEECCCCCCCEEEHH
QALRNLVSLGLPVADVSNRMSRYAADYLGIEDRGRLARGAWADVVVFDRELALTATYVEG
HHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCEEEEEEEECC
ESIVEYA
CHHCCCC
>Mature Secondary Structure
MLTGNILTPEGWIHGTIEFESGRISAIKGDAVDPSKNDAPYILPGFIDLHVHGGGGADVM
CCCCCEECCCCCEEEEEEECCCEEEEEECCCCCCCCCCCCEEECCEEEEEEECCCCCHHH
EAGNAIEAITRTHARFGTTSLLATTMTAPRDELMSVVAGLGDVAKNRVPGGARVLGVHLE
HCCCHHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEC
GPYINPGKLGAQPDAAVSAVLDEVLKYLSIAPIRVVTIAPEISGHMDIISEINARGVRVQ
CCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHCCCCCEEEE
LGHSLGTYDDAVAAMKHGARSFTHLFNAMSALHHRNPGMVGAALAHAEYAEIIPDLLHVH
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCC
PGAIRAAMRAIPRLYVVTDSTSATGMPDGEYRLGSQHVTKCLGGVRLADGTLAGSTLTMD
CHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCEEECCCCCCCEEEHH
QALRNLVSLGLPVADVSNRMSRYAADYLGIEDRGRLARGAWADVVVFDRELALTATYVEG
HHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCEEEEEEEECC
ESIVEYA
CHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA