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The map label for this gene is yegW [H]

Identifier: 186475061

GI number: 186475061

Start: 332679

End: 333413

Strand: Direct

Name: yegW [H]

Synonym: Bphy_0292

Alternate gene names: 186475061

Gene position: 332679-333413 (Clockwise)

Preceding gene: 186475059

Following gene: 186475062

Centisome position: 9.56

GC content: 66.26

Gene sequence:

>735_bases
ATGGAAACCCGTTGGTCCGCACTGACACCCGACGTCCACAACGTCACCCCGCTATACCTGCAGCTCGCCCGCAATCTCGC
GACGGCGATCCATTGCGGCGTGTGGTCGGCGGGTGAGGCGTTGCCGTCGGAGCGCACGTTGTCCGACGCGATCGGCGTGT
CGCGGATCACGGCGCGCAAGGCAATTGCCTTGCTGGTCGAACAGGGTTTGATCCGGCGCGCGCGTGGCGCGGGTAGTTTC
ATCACGCCCCGCGTCGAAGATCCGCTGTCGCGTCTCACCGGGTTCACTAAGAAGATGGAGCAGCGCGGGTTCCGGCCGGA
TTCGGTATGGCTGGAGCGCGGGCTGCGCAACGCGAGCCGCGACGAGATCGTGCATCTGGGTCTGTCGCCGGGCGCGTCAG
TGGCAAGCCTGCGGCGTTTGCGCCGCGCGGACGGCATCGTGATGGCCGTCGAGCATTCGTCGCTGCCCGCGTCGATCGTG
CCCGATCCGCAGGCGATCGGCGGCTCGCTTTATAGCTATCTCGAACAGCGCGGCGCGCCCGTCGTGCGCGCGCTGCAGCA
CTTCCGAGCCGTCAACGCGTCGAGCGAGATCGCCACGCTGATGGACCTCGTACCGGGCAGCGCGCTGCTGCTGATCACGC
GCGTCGGCTACAGCGCCGACCAACGCGCCATTGAACTCACGGACACTTATTGCCGCGACGACTACTACGATTTCGTCGCT
GAATTGCGGCTTTGA

Upstream 100 bases:

>100_bases
TCGATACCACTTCATTGACTGGTATTATGGTGGTTATATAATGGGCTCCGATTTCGTAGGTTAGAGCAGTCCCGACTCCT
CACGATCCCGACCGAGCCAT

Downstream 100 bases:

>100_bases
TCCTGCGTGCAACGAATACATTGAACGCAGACGGCAAAGAATCAGTAACGCACTGCATAACGCAACATCAGAGAGACTCA
TGCTGACCGGAAACATACTC

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
METRWSALTPDVHNVTPLYLQLARNLATAIHCGVWSAGEALPSERTLSDAIGVSRITARKAIALLVEQGLIRRARGAGSF
ITPRVEDPLSRLTGFTKKMEQRGFRPDSVWLERGLRNASRDEIVHLGLSPGASVASLRRLRRADGIVMAVEHSSLPASIV
PDPQAIGGSLYSYLEQRGAPVVRALQHFRAVNASSEIATLMDLVPGSALLLITRVGYSADQRAIELTDTYCRDDYYDFVA
ELRL

Sequences:

>Translated_244_residues
METRWSALTPDVHNVTPLYLQLARNLATAIHCGVWSAGEALPSERTLSDAIGVSRITARKAIALLVEQGLIRRARGAGSF
ITPRVEDPLSRLTGFTKKMEQRGFRPDSVWLERGLRNASRDEIVHLGLSPGASVASLRRLRRADGIVMAVEHSSLPASIV
PDPQAIGGSLYSYLEQRGAPVVRALQHFRAVNASSEIATLMDLVPGSALLLITRVGYSADQRAIELTDTYCRDDYYDFVA
ELRL
>Mature_244_residues
METRWSALTPDVHNVTPLYLQLARNLATAIHCGVWSAGEALPSERTLSDAIGVSRITARKAIALLVEQGLIRRARGAGSF
ITPRVEDPLSRLTGFTKKMEQRGFRPDSVWLERGLRNASRDEIVHLGLSPGASVASLRRLRRADGIVMAVEHSSLPASIV
PDPQAIGGSLYSYLEQRGAPVVRALQHFRAVNASSEIATLMDLVPGSALLLITRVGYSADQRAIELTDTYCRDDYYDFVA
ELRL

Specific function: Unknown

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788418, Length=226, Percent_Identity=34.5132743362832, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1786950, Length=224, Percent_Identity=29.0178571428571, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI87082252, Length=220, Percent_Identity=27.2727272727273, Blast_Score=77, Evalue=8e-16,
Organism=Escherichia coli, GI1790540, Length=212, Percent_Identity=29.2452830188679, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1790118, Length=230, Percent_Identity=25.6521739130435, Blast_Score=64, Evalue=7e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 26764; Mature: 26764

Theoretical pI: Translated: 9.08; Mature: 9.08

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METRWSALTPDVHNVTPLYLQLARNLATAIHCGVWSAGEALPSERTLSDAIGVSRITARK
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
AIALLVEQGLIRRARGAGSFITPRVEDPLSRLTGFTKKMEQRGFRPDSVWLERGLRNASR
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCC
DEIVHLGLSPGASVASLRRLRRADGIVMAVEHSSLPASIVPDPQAIGGSLYSYLEQRGAP
CCEEEECCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCH
VVRALQHFRAVNASSEIATLMDLVPGSALLLITRVGYSADQRAIELTDTYCRDDYYDFVA
HHHHHHHHHHCCCCHHHHHHHHHCCCCCEEHHHHCCCCCCCCEEEHHHHHHHHHHHHHHH
ELRL
HHCC
>Mature Secondary Structure
METRWSALTPDVHNVTPLYLQLARNLATAIHCGVWSAGEALPSERTLSDAIGVSRITARK
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
AIALLVEQGLIRRARGAGSFITPRVEDPLSRLTGFTKKMEQRGFRPDSVWLERGLRNASR
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCC
DEIVHLGLSPGASVASLRRLRRADGIVMAVEHSSLPASIVPDPQAIGGSLYSYLEQRGAP
CCEEEECCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCH
VVRALQHFRAVNASSEIATLMDLVPGSALLLITRVGYSADQRAIELTDTYCRDDYYDFVA
HHHHHHHHHHCCCCHHHHHHHHHCCCCCEEHHHHCCCCCCCCEEEHHHHHHHHHHHHHHH
ELRL
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]