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The map label for this gene is rsbS [H]

Identifier: 186474900

GI number: 186474900

Start: 138874

End: 139230

Strand: Direct

Name: rsbS [H]

Synonym: Bphy_0130

Alternate gene names: 186474900

Gene position: 138874-139230 (Clockwise)

Preceding gene: 186474899

Following gene: 186474901

Centisome position: 3.99

GC content: 59.94

Gene sequence:

>357_bases
ATGGATCGCATTCCAATCCTGCGGATGGGCGATTGCCTGATCGTCGCGATTCAGGTCGATATGCACGACCGTCTCGCCAT
CGCGCTTCAGGACGATCTGACCGCGCGCATCGTGAAGGACAAGGCGAAAGGCGTGCTGATCGACATTTCGGCGCTCGATA
TCGTCGACTCTTTCATTGGCCGCATGATCAGCAACACGGCGGCGATGGCGACCGTGCTCGATGCGCAAACAGTCGTGGTC
GGCATGCAGCCGTCCGTGGCGATCACGCTGGTAGAACTGGGGCTCACGCTGACAGGTGTGCGTACGGCGCTTAATGTCGA
ACGAGGCATGGCGCTGCTCAAGCAGCGACAGCGTTGA

Upstream 100 bases:

>100_bases
GAACGTGATCACGAAGTCGACGCTCGCCGACGCTTTCATCGTCGCGCTGCAAAAAAGCGGTTCGAGCATTTCGACTCGCA
TCGCGAGCTAAGGTGATCAC

Downstream 100 bases:

>100_bases
CCAACCGGGGCGCTCACACATGAACTCATTCGGCGTAGTAGTGACATCGACTGTCGAAGTCGGTCTGCGCTCGGATCAGG
AGATCGTCAAGCTTCGCCAG

Product: anti-sigma-factor antagonist

Products: NA

Alternate protein names: Stressosome protein rsbS [H]

Number of amino acids: Translated: 118; Mature: 118

Protein sequence:

>118_residues
MDRIPILRMGDCLIVAIQVDMHDRLAIALQDDLTARIVKDKAKGVLIDISALDIVDSFIGRMISNTAAMATVLDAQTVVV
GMQPSVAITLVELGLTLTGVRTALNVERGMALLKQRQR

Sequences:

>Translated_118_residues
MDRIPILRMGDCLIVAIQVDMHDRLAIALQDDLTARIVKDKAKGVLIDISALDIVDSFIGRMISNTAAMATVLDAQTVVV
GMQPSVAITLVELGLTLTGVRTALNVERGMALLKQRQR
>Mature_118_residues
MDRIPILRMGDCLIVAIQVDMHDRLAIALQDDLTARIVKDKAKGVLIDISALDIVDSFIGRMISNTAAMATVLDAQTVVV
GMQPSVAITLVELGLTLTGVRTALNVERGMALLKQRQR

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645 [H]

Pfam domain/function: PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 12782; Mature: 12782

Theoretical pI: Translated: 7.36; Mature: 7.36

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
5.9 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
5.9 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRIPILRMGDCLIVAIQVDMHDRLAIALQDDLTARIVKDKAKGVLIDISALDIVDSFIG
CCCCCEEEECCEEEEEEEECCCCEEEEEECCCCHHHHHHHCCCEEEEEHHHHHHHHHHHH
RMISNTAAMATVLDAQTVVVGMQPSVAITLVELGLTLTGVRTALNVERGMALLKQRQR
HHHHCHHHHHHHHCCEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDRIPILRMGDCLIVAIQVDMHDRLAIALQDDLTARIVKDKAKGVLIDISALDIVDSFIG
CCCCCEEEECCEEEEEEEECCCCEEEEEECCCCHHHHHHHCCCEEEEEHHHHHHHHHHHH
RMISNTAAMATVLDAQTVVVGMQPSVAITLVELGLTLTGVRTALNVERGMALLKQRQR
HHHHCHHHHHHHHCCEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 8824586; 8682789 [H]